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Leukemia & Lymphoma Volume 42, 2001 - Issue 1-2
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Original Article

Leukapheresis Reduces Early Mortality in Patients with Acute Myeloid Leukemia with High White Cell Counts But Does Not Improve Long Term Survival

Francis J. Giles From the Departments of Leukemia, Biostatistics, and Blood and Marrow Transplantation, University of Texas M.D. Anderson Cancer Center, Houston, TX, USACorrespondence[email protected]
,
Yu Shen From the Departments of Leukemia, Biostatistics, and Blood and Marrow Transplantation, University of Texas M.D. Anderson Cancer Center, Houston, TX, USA
,
Hagop M. Kantarjian From the Departments of Leukemia, Biostatistics, and Blood and Marrow Transplantation, University of Texas M.D. Anderson Cancer Center, Houston, TX, USA
,
Martin J. Korbling From the Departments of Leukemia, Biostatistics, and Blood and Marrow Transplantation, University of Texas M.D. Anderson Cancer Center, Houston, TX, USA
,
Susan O'brien From the Departments of Leukemia, Biostatistics, and Blood and Marrow Transplantation, University of Texas M.D. Anderson Cancer Center, Houston, TX, USA
,
Paolo Anderlini From the Departments of Leukemia, Biostatistics, and Blood and Marrow Transplantation, University of Texas M.D. Anderson Cancer Center, Houston, TX, USA
,
Michele Donato From the Departments of Leukemia, Biostatistics, and Blood and Marrow Transplantation, University of Texas M.D. Anderson Cancer Center, Houston, TX, USA
,
Sherry Pierce From the Departments of Leukemia, Biostatistics, and Blood and Marrow Transplantation, University of Texas M.D. Anderson Cancer Center, Houston, TX, USA
,
Michael J. Keating From the Departments of Leukemia, Biostatistics, and Blood and Marrow Transplantation, University of Texas M.D. Anderson Cancer Center, Houston, TX, USA
,
Emil J. Freireich From the Departments of Leukemia, Biostatistics, and Blood and Marrow Transplantation, University of Texas M.D. Anderson Cancer Center, Houston, TX, USA
&
Elihu Estey From the Departments of Leukemia, Biostatistics, and Blood and Marrow Transplantation, University of Texas M.D. Anderson Cancer Center, Houston, TX, USA
 show all
Pages 67-73 | Published online: 01 Jul 2009

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Robert W. Maitta. (2018) Current state of apheresis technology and its applications. Transfusion and Apheresis Science 57:5, pages 606-613.
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Nicole Aqui & Una O'Doherty. (2014) Leukocytapheresis for the treatment of hyperleukocytosis secondary to acute leukemia. Hematology 2014:1, pages 457-460.
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P. Schellongowski & T. Staudinger. (2013) Leukostase und TumorlyseLeukostasis and tumor lysis. Der Internist 54:9, pages 1051-1060.
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Claire L. Barrett, Vernon J. Louw & Michael J. Webb. (2013) WITHDRAWN: Exchange transfusion as a life-saving intervention in three patients with different haematological malignancies with severe hyperleukocytosis where leukapheresis was not available. Transfusion and Apheresis Science.
Crossref
Joseph Schwartz, Jeffrey L. Winters, Anand Padmanabhan, Rasheed A. Balogun, Meghan Delaney, Michael L. Linenberger, Zbigniew M. Szczepiorkowski, Mark E. Williams, Yanyun Wu & Beth H. Shaz. (2013) Guidelines on the Use of Therapeutic Apheresis in Clinical Practice—Evidence‐Based Approach from the Writing Committee of the American Society for Apheresis: The Sixth Special Issue. Journal of Clinical Apheresis 28:3, pages 145-284.
Crossref
Huy P. Pham & Joseph Schwartz. 2013. Transfusion Medicine and Hemostasis. Transfusion Medicine and Hemostasis 511 514 .
Janice P. Dutcher. 2013. Neoplastic Diseases of the Blood. Neoplastic Diseases of the Blood 1241 1249 .
Gurhan Kadikoylu, Irfan Yavasoglu, Ayca Ozkul, Ali Akyol, Vahit Yukselen, Engin Guney & Zahit Bolaman. (2012) The single center registry for therapeutic apheresis in Turkey: 11-year activity. Transfusion and Apheresis Science 47:1, pages 61-65.
Crossref
Marieke H. van der Linden, Sara Creemers & Rob Pieters. (2012) Diagnosis and management of neonatal leukaemia. Seminars in Fetal and Neonatal Medicine 17:4, pages 192-195.
Crossref
F. Vincent, M.-A. Hospital, V. Lemiale, F. Bruneel, M. Darmon, F. Gonzalez, A. Kouatchet, D. Mokart, F. Pène, A. Rabbat, Y. Cohen & E. Azoulay. (2012) Prise en charge thérapeutique des manifestations pulmonaires à la phase aiguë des leucémies aiguës myéloblastiques. Revue des Maladies Respiratoires 29:6, pages 743-755.
Crossref
Chezi Ganzel, Joanne Becker, Paul D. Mintz, Hillard M. Lazarus & Jacob M. Rowe. (2012) Hyperleukocytosis, leukostasis and leukapheresis: Practice management. Blood Reviews 26:3, pages 117-122.
Crossref
Elihu H. Estey, Elihu H. Estey & Elihu H. Estey. 2012. Leukemia and Related Disorders. Leukemia and Related Disorders 1 36 .
Elihu H. Estey. (2011) Acute myeloid leukemia: 2012 update on diagnosis, risk stratification, and management. American Journal of Hematology 87:1, pages 89-99.
Crossref
Ratti Ram Sharma, Karan Saluja, Ashish Jain, Hari Krishan Dhawan, Beenu Thakral & Neelam Marwaha. (2011) Scope and application of therapeutic apheresis: Experience from a tertiary care hospital in North India. Transfusion and Apheresis Science 45:3, pages 239-245.
Crossref
Eugenio Piro, Guido Carillio, Luciano Levato, Mariagrazia Kropp & Stefano Molica. (2011) Reversal of Leukostasis-Related Pulmonary Distress Syndrome After Leukapheresis and Low-Dose Chemotherapy in Acute Myeloid Leukemia. Journal of Clinical Oncology 29:26, pages e725-e726.
Crossref
Jeffrey L. Winters. 2011. Henry's Clinical Diagnosis and Management by Laboratory Methods. Henry's Clinical Diagnosis and Management by Laboratory Methods 746 773 .
François Vincent. 2011. Pulmonary Involvement in Patients with Hematological Malignancies. Pulmonary Involvement in Patients with Hematological Malignancies 509 520 .
Gil Cunha De Santis, Luciana Correa Oliveira de Oliveira, Lucas Gabriel Maltoni Romano, Benedito de Pina Almeida PradoJr.Jr., Belinda Pinto Simoes, Eduardo Magalhaes Rego, Dimas Tadeu Covas & Roberto Passetto Falcao. (2011) Therapeutic leukapheresis in patients with leukostasis secondary to acute myelogenous leukemia. Journal of Clinical Apheresis 26:4, pages 181-185.
Crossref
L. C. O. Oliveira, L. G. M. Romano, B. P. A. Prado-Junior, D. T. Covas, E. M. Rego & G. C. De Santis. (2009) Outcome of acute myeloid leukemia patients with hyperleukocytosis in Brazil. Medical Oncology 27:4, pages 1254-1259.
Crossref
Hartmut DöhnerElihu H. EsteySergio AmadoriFrederick R. AppelbaumThomas BüchnerAlan K. BurnettHervé DombretPierre FenauxDavid GrimwadeRichard A. LarsonFrancesco Lo-CocoTomoki NaoeDietger NiederwieserGert J. OssenkoppeleMiguel A. SanzJorge SierraMartin S. TallmanBob Löwenberg & Clara D. Bloomfield. (2010) Diagnosis and management of acute myeloid leukemia in adults: recommendations from an international expert panel, on behalf of the European LeukemiaNet. Blood 115:3, pages 453-474.
Crossref
B. Mansouri Taleghani. 2011. Transfusionsmedizin und Immunhämatologie. Transfusionsmedizin und Immunhämatologie 457 478 .
Zbigniew M. Szczepiorkowski, Jeffrey L. Winters, Nicholas Bandarenko, Haewon C. Kim, Michael L. Linenberger, Marisa B. Marques, Ravindra Sarode, Joseph Schwartz, Robert Weinstein & Beth H. Shaz. (2010) Guidelines on the use of therapeutic apheresis in clinical practice—Evidence‐based approach from the apheresis applications committee of the American Society for Apheresis. Journal of Clinical Apheresis 25:3, pages 83-177.
Crossref
Elizabeth Mullen, Jennifer Whangbo & Lynda M. Vrooman. 2009. Oncology of Infancy and Childhood. Oncology of Infancy and Childhood 1121 1143 .
Jennifer J. Clark, Jason N. Berman & A. Thomas Look. 2009. Oncology of Infancy and Childhood. Oncology of Infancy and Childhood 331 402 .
Raul C. Ribeiro, Carlos Rodriguez-Galindo & Guillermo Chantada. 2009. Pulmonary Manifestations of Pediatric Diseases. Pulmonary Manifestations of Pediatric Diseases 135 169 .
Laura Marbello, Francesca Ricci, Anna Maria Nosari, Mauro Turrini, Guido Nador, Michele Nichelatti, Alessandra Tedeschi, Eleonora Vismara & Enrica Morra. (2008) Outcome of hyperleukocytic adult acute myeloid leukaemia: A single-center retrospective study and review of literature. Leukemia Research 32:8, pages 1221-1227.
Crossref
Ming‐Chih Chang, Tsai‐Yun Chen, Jih‐Luh Tang, Yii‐Jenq Lan, Tsu‐Yi Chao, Chang‐Fang Chiu & Hsin‐Tsung Ho. (2007) Leukapheresis and cranial irradiation in patients with hyperleukocytic acute myeloid leukemia: No impact on early mortality and intracranial hemorrhage. American Journal of Hematology 82:11, pages 976-980.
Crossref
Gesine Bug, Konstantinos Anargyrou, Torsten Tonn, Heike Bialleck, Erhard Seifried, Dieter Hoelzer & Oliver G. Ottmann. (2007) Impact of leukapheresis on early death rate in adult acute myeloid leukemia presenting with hyperleukocytosis. Transfusion 47:10, pages 1843-1850.
Crossref
Irfan Yavasoglu, Gurhan Kadikoylu, Ali Akyol & Zahit Bolaman. (2007) Therapeutic apheresis: Results from a single center in Turkey. Transfusion and Apheresis Science 36:3, pages 249-253.
Crossref
Zbigniew M. Szczepiorkowski, Nicholas Bandarenko, Haewon C. Kim, Michael L. Linenberger, Marisa B. Marques, Ravindra Sarode, Joseph Schwartz, Beth H. Shaz, Robert Weinstein, Ashka Wirk & Jeffrey L. Winters. (2007) Guidelines on the use of therapeutic apheresis in clinical practice—Evidence‐based approach from the apheresis applications committee of the American society for apheresis. Journal of Clinical Apheresis 22:3, pages 106-175.
Crossref
Chelsea A. Sheppard & Christopher D. Hillyer. 2007. Consultative Hemostasis and Thrombosis. Consultative Hemostasis and Thrombosis 509 529 .
Bruce C. McLeod. 2007. Blood Banking and Transfusion Medicine. Blood Banking and Transfusion Medicine 765 779 .
Eve Rodler & Ted Wun. 2010. Medical Management of the Surgical Patient. Medical Management of the Surgical Patient 230 247 .
Thorvardur R. Halfdanarson, William J. Hogan & Timothy J. Moynihan. (2006) Oncologic Emergencies: Diagnosis and Treatment. Mayo Clinic Proceedings 81:6, pages 835-848.
Crossref
SK Magu & AK Malviya. (2006) Fatal Cerebral Leucostasis in Acute Leukaemia with Hyperleucocytosis. Medical Journal Armed Forces India 62:2, pages 192-193.
Crossref
Elias J. Jabbour, Elihu Estey & Hagop M. Kantarjian. (2006) Adult Acute Myeloid Leukemia. Mayo Clinic Proceedings 81:2, pages 247-260.
Crossref
. 2005. Mollison's Blood Transfusion in Clinical Medicine. Mollison's Blood Transfusion in Clinical Medicine 774 809 .
Eric J. Lowe, Ching-Hon Pui, Michael L. Hancock, Terrence L. Geiger, Raja B. Khan & John T. Sandlund. (2005) Early complications in children with acute lymphoblastic leukemia presenting with hyperleukocytosis. Pediatric Blood & Cancer 45:1, pages 10-15.
Crossref
D Tan, W Hwang & YT Goh. (2005) Therapeutic Leukapheresis in Hyperleukocytic Leukaemias—The Experience of a Tertiary Institution in Singapore. Annals of the Academy of Medicine, Singapore 34:3, pages 229-234.
Crossref
A M Slats, R M Egeler, A van der Does-van den Berg, C Korbijn, K Hählen, W A Kamps, A J P Veerman & C M Zwaan. (2005) Causes of death – other than progressive leukemia – in childhood acute lymphoblastic (ALL) and myeloid leukemia (AML): the Dutch Childhood Oncology Group experience. Leukemia 19:4, pages 537-544.
Crossref
Michael L. LinenbergerThomas H. Price. (2016) Use of Cellular and Plasma Apheresis in the Critically Ill Patient: Part II: Clinical Indications and Applications. Journal of Intensive Care Medicine 20:2, pages 88-103.
Crossref
Francis J. Giles & Elihu Estey. (2002) Letter to the Editor Leukapheresis in Patients with Previously Untreated Acute Myeloid Leukemia. Therapeutic Apheresis 6:5, pages 399-400.
Crossref
Elihu Estey. (2001) Reducing mortality associated with immediate treatment complications of adult leukemias. Seminars in Hematology 38, pages 32-37.
Crossref

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