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Leukemia & Lymphoma Volume 51, 2010 - Issue 5
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Original Articles: Clinical

Methylenetetrahydrofolate reductase gene polymorphisms: association with risk for pediatric acute lymphoblastic leukemia in north Indians

Swati SoodDepartments of Hematology
,
Reena DasDepartments of HematologyCorrespondence[email protected]
,
Amita TrehanDepartments of Paediatrics, Postgraduate Institute of Medical Education and Research, Chandigarh, India
,
Jasmina AhluwaliaDepartments of Hematology
,
Man Updesh SachdevaDepartments of Hematology
,
Neelam VarmaDepartments of Hematology
,
Deepak BansalDepartments of Paediatrics, Postgraduate Institute of Medical Education and Research, Chandigarh, India
&
Ram Kumar MarwahaDepartments of Paediatrics, Postgraduate Institute of Medical Education and Research, Chandigarh, India
 show all
Pages 928-932 | Received 19 Dec 2009, Accepted 20 Feb 2009, Published online: 06 Apr 2010

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Xiaojun Xia, Yun Duan, Jie Cui, Junfeng Jiang, Li Lin, Xiaojuan Peng, YuHong Wang, Bingtao Guo, Shouhai Liu & Xudong Lei. (2017) Association of methylenetetrahydrofolate reductase gene–gene interaction and haplotype with susceptibility to acute lymphoblastic leukemia in Chinese children. Leukemia & Lymphoma 58:8, pages 1887-1892.
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Ravishankara Bellampalli, Nagaraja M. Phani, Kamalakshi G. Bhat, Krishna Prasad, Nalini Bhaskaranand, Kanive P. Guruprasad, Padmalatha S. Rai & Kapaettu Satyamoorthy. (2015) Significance of 5,10-methylenetetrahydrofolate reductase gene variants in acute lymphoblastic leukemia in Indian population: an experimental, computational and meta-analysis. Leukemia & Lymphoma 56:5, pages 1450-1459.
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Articles from other publishers (19)

Sushma Devi, Jyotdeep Kour Raina, Pawan Kumar, Amrit Sudershan, Ravi Sharma, Rakesh K. Panjalyia, Sanjeev K. Digra & Parvinder Kumar. (2023) Genetic association study of rs1801133 of MTHFR, rs4646903 of CYP1A1, null mutation of GSTM1&GSTT1 with leukemia in the Jammu region of north Indian population. The Nucleus.
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Rim Frikha. (2021) Lack of Impact of the A1298C MTHFR on the Risk of Childhood Acute Lymphoblastic Leukemia: Evidence from a Meta-analysis. Indian Journal of Hematology and Blood Transfusion 38:2, pages 255-263.
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Rim Frikha. (2020) Assessment of the relationship between methylenetetrahydrofolate reductase polymorphism and acute lymphoblastic leukemia: Evidence from an updated meta-analysis. Journal of Oncology Pharmacy Practice 26:7, pages 1598-1610.
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Xiaolei Li, Shunguo Zhang & Feng Yu. (2019) Rs4846049 Polymorphism at the 3′-UTR of MTHFR Gene: Association with Susceptibility to Childhood Acute Lymphoblastic Leukemia. BioMed Research International 2019, pages 1-12.
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Yazmín Gómez-Gómez, Jorge Organista-Nava, Fernando Villanueva-Flores, José Silvestre Estrada-Brito, Ana Bertha Rivera-Ramírez, Mónica Virginia Saavedra-Herrera, Marco Antonio Jiménez-López, Berenice Illades-Aguiar & Marco Antonio Leyva-Vázquez. (2019) Association Between the 5,10-MTHFR 677C>T and RFC1 80G>A Polymorphisms and Acute Lymphoblastic Leukemia. Archives of Medical Research 50:4, pages 175-180.
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Beibei Zhang, Weiming Zhang, Liang Yan & Daogang Wang. (2017) The association between MTHFR gene C677T polymorphism and ALL risk based on a meta-analysis involving 17,469 subjects. Clinica Chimica Acta 466, pages 85-92.
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Claudia Bănescu, Mihaela Iancu, Adrian P. Trifa, Ioan Macarie, Delia Dima & Minodora Dobreanu. (2014) The methylenetetrahydrofolate reductase (MTHFR) 677 C>T polymorphism increases the risk of developing chronic myeloid leukemia—a case-control study. Tumor Biology 36:4, pages 3101-3107.
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Jen-Sheng Pei, Chin-Mu Hsu, Chia-Wen Tsai, Wen-Shin Chang, Hong-Xue Ji, Chieh-Lun Hsiao, Chia-En Miao, Yuan-Nian Hsu & Da-Tian Bau. (2015) The Association of Methylenetetrahydrofolate Reductase Genotypes with the Risk of Childhood Leukemia in Taiwan. PLOS ONE 10:3, pages e0119776.
Crossref
Mo Yang. (2015) Association between MTHFR C677T Polymorphism and Risk of Acute Lymphoblastic Leukemia: A Meta-Analysis Based on 51 Case-Control Studies. Medical Science Monitor 21, pages 740-748.
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Sudha Sazawal, Rekha Chaubey, Pawandeep Kaur, Sunita Chikkara, Bijender Kumar, Sameer Bakshi, L. S. Arya, Vinod Raina, Alakananda Das Gupta & Renu Saxena. (2013) MTHFR Gene Polymorphisms and the Risk of Acute Lymphoblastic Leukemia in Adults and Children: A Case Control Study in India. Indian Journal of Hematology and Blood Transfusion 30:4, pages 219-225.
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Nirmalya Roy Moulik, Farah Parveen, Archana Kumar, Shally Awasthi & Suraksha Agrawal. (2014) MTHFR gene polymorphism in acute lymphoblastic leukemia among North Indian children: a case–control study and meta-analysis updated from 2011. Journal of Human Genetics 59:7, pages 397-404.
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Yuan Jiang, Jing Hou, Qiang Zhang, Shu-Ting Jia, Bo-Yuan Wang, Ji-Hong Zhang, Wen-Ru Tang & Ying Luo. (2013) The MTHFR C677T Polymorphism and Risk of Acute Lymphoblastic Leukemia: an Updated Meta-analysis Based on 37 Case-control Studies. Asian Pacific Journal of Cancer Prevention 14:11, pages 6357-6362.
Crossref
Muzeyyen Izmirli. (2012) A literature review of MTHFR (C677T and A1298C polymorphisms) and cancer risk. Molecular Biology Reports 40:1, pages 625-637.
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Haigang Wang, Jiali Wang, Lixia Zhao, Xinchun Liu & Wenjie Mi. (2012) Methylenetetrahydrofolate Reductase Polymorphisms and Risk of Acute Lymphoblastic Leukemia-Evidence from an updated meta-analysis including 35 studies. BMC Medical Genetics 13:1.
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Valentina Djordjevic, Marija Stankovic, Vesna Brankovic-Sreckovic, Ljiljana Rakicevic, Tatjana Damnjanovic, Nebojsa Antonijevic & Dragica Radojkovic. (2012) Prothrombotic Genetic Risk Factors in Stroke. Clinical and Applied Thrombosis/Hemostasis 18:6, pages 658-661.
Crossref
Piotr Pawlik, Adrianna Mostowska, Margarita Lianeri, Stefan Sajdak, Helena K?dzia & Pawe? P. Jagodzinski. (2011) Folate and choline metabolism gene variants in relation to ovarian cancer risk in the Polish population. Molecular Biology Reports 39:5, pages 5553-5560.
Crossref
Elias Zintzaras, Chrysoula Doxani, Paraskevi Rodopoulou, Georgios Bakalos, Dimitris C. Ziogas, Panayiotis Ziakas & Michael Voulgarelis. (2012) Variants of the MTHFR gene and susceptibility to acute lymphoblastic leukemia in children: A synthesis of genetic association studies. Cancer Epidemiology 36:2, pages 169-176.
Crossref
Jingrong Yan, Ming Yin, ZoAnn E. Dreyer, Michael E. Scheurer, Kala Kamdar, Qingyi Wei & M. Fatih Okcu. (2011) A meta‐analysis of MTHFR C677T and A1298C polymorphisms and risk of acute lymphoblastic leukemia in children . Pediatric Blood & Cancer 58:4, pages 513-518.
Crossref
Radoslav Židek, Jozef Golian & Jozef Bulla. (2011) Nutrigenomic analysis of C677T mutation of MTHFR gene in Slovak population. Potravinarstvo Slovak Journal of Food Sciences 5:2, pages 73-76.
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