1,033
Views
89
CrossRef citations to date
0
Altmetric
Original Articles: Research

Sensitive quantitation of minimal residual disease in chronic myeloid leukemia using nanofluidic digital polymerase chain reaction assay

, , , , , , , , , & show all
Pages 896-904 | Received 12 Oct 2010, Accepted 12 Jan 2011, Published online: 21 Feb 2011

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (14)

Li Ling Tan, Nitin Loganathan, Sushama Agarwalla, Chun Yang, Weiyong Yuan, Jasmine Zeng, Ruige Wu, Wei Wang & Suhanya Duraiswamy. (2023) Current commercial dPCR platforms: technology and market review. Critical Reviews in Biotechnology 43:3, pages 433-464.
Read now
Cosimo Cumbo, Luisa Anelli, Giorgina Specchia & Francesco Albano. (2020) Monitoring of Minimal Residual Disease (MRD) in Chronic Myeloid Leukemia: Recent Advances. Cancer Management and Research 12, pages 3175-3189.
Read now
Jesus G. Berdeja, Michael C. Heinrich, Shaker R. Dakhil, Stuart L. Goldberg, Martha Wadleigh, Philip Kuriakose, Jorge Cortes, Jerald Radich, Bret Helton, David Rizzieri, Carole Paley, Ilva Dautaj & Michael J. Mauro. (2019) Rates of deep molecular response by digital and conventional PCR with frontline nilotinib in newly diagnosed chronic myeloid leukemia: a landmark analysis. Leukemia & Lymphoma 60:10, pages 2384-2393.
Read now
Vincent Camus, Elodie Bohers, Sydney Dubois, Hervé Tilly & Fabrice Jardin. (2018) Circulating tumor DNA: an important tool in precision medicine for lymphoma. Expert Review of Precision Medicine and Drug Development 3:1, pages 11-21.
Read now
Raquel Vinhas, Milton Cordeiro, Pedro Pedrosa, Alexandra R. Fernandes & Pedro V. Baptista. (2017) Current trends in molecular diagnostics of chronic myeloid leukemia. Leukemia & Lymphoma 58:8, pages 1791-1804.
Read now
Vincent Camus, Fabrice Jardin & Herve Tilly. (2017) The value of liquid biopsy in diagnosis and monitoring of diffuse large b-cell lymphoma: recent developments and future potential. Expert Review of Molecular Diagnostics 17:6, pages 557-566.
Read now
Y. K. Wong, H. F. Tsang, V. W. Xue, C. M. Chan, T. C. Au, W. C. Cho, L. W. Chan & S. C. Wong. (2017) Applications of digital PCR in precision medicine. Expert Review of Precision Medicine and Drug Development 2:3, pages 177-186.
Read now
Cecilia Ching Sze Yeung, Daniel Egan & Jerald P Radich. (2016) Molecular monitoring of chronic myeloid leukemia: present and future. Expert Review of Molecular Diagnostics 16:10, pages 1083-1091.
Read now
Vincent Camus, Nasrin Sarafan-Vasseur, Elodie Bohers, Sydney Dubois, Sylvain Mareschal, Philippe Bertrand, Pierre-Julien Viailly, Philippe Ruminy, Catherine Maingonnat, Emilie Lemasle, Aspasia Stamatoullas, Jean-Michel Picquenot, Marie Cornic, Ludivine Beaussire, Christian Bastard, Thierry Frebourg, Hervé Tilly & Fabrice Jardin. (2016) Digital PCR for quantification of recurrent and potentially actionable somatic mutations in circulating free DNA from patients with diffuse large B-cell lymphoma. Leukemia & Lymphoma 57:9, pages 2171-2179.
Read now
Yanjing Tang, Xiaoyuan Wei, Jing Chen, Yunzhi Du, Huiling Chu, Louise Mao, Jun Chen, Qing Xu, Jingyan Tang, Shuhong Shen & Mao Mao. (2016) Absolute quantification of BCR-ABL1 fusion transcripts in pediatric chronic myeloid leukemia. Leukemia & Lymphoma 57:9, pages 2216-2218.
Read now
Sung-Eun Lee, Soo Young Choi, Soo-Hyun Kim, Eun-Jung Jang, Ju-Hee Bang, Ji-Young Byeun, Jin Eok Park, Hye-Rim Jeon, Yun Jeong Oh, Seung-Ah Yahng, Byung-Sik Cho, Ki-Sung Eom, Yoo-Jin Kim, Seok Lee, Chang-Ki Min, Hee-Je Kim, Jong-Wook Lee, Woo-Sung Min, Chong-Won Park & Dong-Wook Kim. (2014) Prognostic factors for outcomes of allogeneic stem cell transplantation in chronic phase chronic myeloid leukemia in the era of tyrosine kinase inhibitors. Hematology 19:2, pages 63-72.
Read now
Elias J. Jabbour & Alfonso Quintás-Cardama. (2012) Molecular monitoring 101: helping your patients with chronic myeloid leukemia to understand the meaning of molecular response. Leukemia & Lymphoma 53:8, pages 1452-1460.
Read now
Joanne Mason & Michael Griffiths. (2012) Molecular diagnosis of leukemia. Expert Review of Molecular Diagnostics 12:5, pages 511-526.
Read now
David M. Ross & Susan Branford. (2011) Minimal residual disease: the advantages of digital over analog polymerase chain reaction. Leukemia & Lymphoma 52:7, pages 1161-1163.
Read now

Articles from other publishers (75)

Deepak Kumar Mishra, Indranil Dey, Rakesh Demde, Sushant Vinarkar & Mayur Parihar. (2023) Disease Response Assessment Modalities in Chronic Myeloid Leukemia: Past, Present, and Future. Indian Journal of Medical and Paediatric Oncology 44:06, pages 592-601.
Crossref
Maroun Bou Zerdan, Joseph Kassab, Ludovic Saba, Elio Haroun, Morgan Bou Zerdan, Sabine Allam, Lewis Nasr, Walid Macaron, Mahinbanu Mammadli, Sarah Abou Moussa & Chakra P. Chaulagain. (2023) Liquid biopsies and minimal residual disease in lymphoid malignancies. Frontiers in Oncology 13.
Crossref
Irene Della Starza, Lucia Anna De Novi, Loredana Elia, Vittorio Bellomarino, Marco Beldinanzi, Roberta Soscia, Deborah Cardinali, Sabina Chiaretti, Anna Guarini & Robin Foà. (2023) Optimizing Molecular Minimal Residual Disease Analysis in Adult Acute Lymphoblastic Leukemia. Cancers 15:2, pages 374.
Crossref
Nora Chokr & Alexandra Gomez-Arteaga. (2023) Measurable residual disease after CAR T-cell therapy. Seminars in Hematology 60:1, pages 34-41.
Crossref
Simona Bernardi, Michele Malagola, Mirko Farina, Nicola Polverelli, Federica Re & Domenico Russo. (2022) Digital PCR as a New Method for Minimal Residual Disease Monitoring and Treatment Free Remission Management in Chronic Myeloid Leukemia Patients: Is It Reliable?. Hemato 4:1, pages 1-11.
Crossref
Susan Branford & Jane F. Apperley. (2022) Measurable residual disease in chronic myeloid leukemia. Haematologica 107:12, pages 2794-2809.
Crossref
Dawne N. Shelton, Prasanthi Bhagavatula, Nathan Sepulveda, Lan Beppu, Shital Gandhi, Dahui Qin, Scott Hauenstein & Jerald Radich. (2022) Performance characteristics of the first Food and Drug Administration (FDA)-cleared digital droplet PCR (ddPCR) assay for BCR::ABL1 monitoring in chronic myelogenous leukemia. PLOS ONE 17:3, pages e0265278.
Crossref
Helong ZhaoAnthony D. Pomicter, Anna M. Eiring, Anca Franzini, Jonathan AhmannJae-Yeon HwangAnna SeninaBret HeltonSiddharth IyerDongqing YanJamshid S. KhorashadMatthew S. Zabriskie, Anupriya AgarwalHannah M. RedwineAmber D. Bowler, Phillip M. ClairShannon K. McWeeneyBrian J. Druker, Jeffrey W. TynerDerek L. Stirewalt, Vivian G. Oehler, Sooryanarayana Varambally, Kristofer C. BerrettJeffery M. VahrenkampJason GertzKatherine E. VarleyJerald P. Radich & Michael W. Deininger. (2022) MS4A3 promotes differentiation in chronic myeloid leukemia by enhancing common β-chain cytokine receptor endocytosis. Blood 139:5, pages 761-778.
Crossref
Maria Teresa Bochicchio, Jessica Petiti, Paola Berchialla, Barbara Izzo, Emilia Giugliano, Emanuela Ottaviani, Santa Errichiello, Giovanna Rege-Cambrin, Claudia Venturi, Luigiana Luciano, Filomena Daraio, Daniele Calistri, Gianantonio Rosti, Giuseppe Saglio, Giovanni Martinelli, Fabrizio Pane, Daniela Cilloni, Enrico M. Gottardi & Carmen Fava. (2021) Droplet Digital PCR for BCR–ABL1 Monitoring in Diagnostic Routine: Ready to Start?. Cancers 13:21, pages 5470.
Crossref
Jerry Radich. (2021) Building a better mousetrap for accurate and sensitive polymerase chain reaction. British Journal of Haematology 194:1, pages 11-13.
Crossref
Carmen Fava, Simona Bernardi, Enrico Marco Gottardi, Roberta Lorenzatti, Laura Galeotti, Francesco Ceccherini, Francesco Cordoni, Filomena Daraio, Emilia Giugliano, Aleksandar Jovanovski, Jessica Petiti, Marta Varotto, Davide Barberio, Giovanna Rege-Cambrin, Paola Berchialla, Veronica Sciannameo, Michele Malagola, Giuseppe Saglio & Domenico Russo. (2021) Alignment of Qx100/Qx200 Droplet Digital (Bio-Rad) and QuantStudio 3D (Thermofisher) Digital PCR for Quantification of BCR-ABL1 in Ph+ Chronic Myeloid Leukemia. Diseases 9:2, pages 35.
Crossref
Gioia Colafigli, Emilia Scalzulli, Alessio Di Prima, Sara Pepe, Maria Giovanna Loglisci, Daniela Diverio, Maurizio Martelli, Robin Foà & Massimo Breccia. (2021) Digital droplet PCR as a predictive tool for successful discontinuation outcome in chronic myeloid leukemia: Is it time to introduce it in the clinical practice?. Critical Reviews in Oncology/Hematology 157, pages 103163.
Crossref
Camille C.B. Kockerols, Peter J.M. Valk, Mark-David Levin, Niels PallisgaardJan J. Cornelissen & Peter E. Westerweel. (2020) Digital PCR for BCR-ABL1 Quantification in CML: Current Applications in Clinical Practice. HemaSphere 4:6, pages e496.
Crossref
Simona Soverini, Simona Bernardi & Sara Galimberti. (2020) Molecular Testing in CML between Old and New Methods: Are We at a Turning Point?. Journal of Clinical Medicine 9:12, pages 3865.
Crossref
Aleksandar Jovanovski, Jessica Petiti, Emilia Giugliano, Enrico Marco Gottardi, Giuseppe Saglio, Daniela Cilloni & Carmen Fava. (2020) Standardization of BCR-ABL1 p210 Monitoring: From Nested to Digital PCR. Cancers 12:11, pages 3287.
Crossref
Susan Branford. (2020) Why is it critical to achieve a deep molecular response in chronic myeloid leukemia?. Haematologica 105:12, pages 2730-2737.
Crossref
Giuseppe Saglio & Robert P. Gale. (2020) Prospects for achieving treatment‐free remission in chronic myeloid leukaemia. British Journal of Haematology 190:3, pages 318-327.
Crossref
Avyakta Kallam, Jayanth Adusumalli, Kai Fu & James O. Armitage. (2020) Circulating tumor DNA in lymphomas: Era of precision medicine. ADVANCES IN CELL AND GENE THERAPY 3:3.
Crossref
Nicoletta Coccaro, Giuseppina Tota, Luisa Anelli, Antonella Zagaria, Giorgina Specchia & Francesco Albano. (2020) Digital PCR: A Reliable Tool for Analyzing and Monitoring Hematologic Malignancies. International Journal of Molecular Sciences 21:9, pages 3141.
Crossref
Gioia Colafigli, Emilia Scalzulli, Marika Porrazzo, Daniela Diverio, Maria Giovanna Loglisci, Roberto Latagliata, Anna Guarini, Robin Foà & Massimo Breccia. (2019) Digital droplet PCR at the time of TKI discontinuation in chronic‐phase chronic myeloid leukemia patients is predictive of treatment‐free remission outcome. Hematological Oncology 37:5, pages 652-654.
Crossref
Jerald Radich, Cecilia Yeung & David Wu. (2019) New approaches to molecular monitoring in CML (and other diseases). Blood 134:19, pages 1578-1584.
Crossref
Zhiling Yan, Qian Sun, Huanxin Zhang, Yahui Han, Jianlin Qiao, Mingshan Niu, Shengyun Zhu, Kai Zhao, Qingyun Wu, Hai Cheng, Jiang Cao, Lingyu Zeng, Zhenyu Li & Kailin Xu. (2019) Advantages of digital PCR in the detection of low abundance BCR‑ABL1 gene in patients with chronic myeloid leukemia. Oncology Letters.
Crossref
Barbara Izzo, Enrico Marco Gottardi, Santa Errichiello, Filomena Daraio, Claudia Baratè & Sara Galimberti. (2019) Monitoring Chronic Myeloid Leukemia: How Molecular Tools May Drive Therapeutic Approaches. Frontiers in Oncology 9.
Crossref
Christine M. O’Keefe, Aniruddha M. Kaushik & Tza-Huei Wang. (2019) Highly Efficient Real-Time Droplet Analysis Platform for High-Throughput Interrogation of DNA Sequences by Melt. Analytical Chemistry 91:17, pages 11275-11282.
Crossref
Mohammad Houshmand, Giorgia Simonetti, Paola Circosta, Valentina Gaidano, Alessandro Cignetti, Giovanni Martinelli, Giuseppe Saglio & Robert Peter Gale. (2019) Chronic myeloid leukemia stem cells. Leukemia 33:7, pages 1543-1556.
Crossref
Daisuke Furuya, Mikako Moriai, Yuki Koizumi, Teruo Endo, Kouichi Asanuma, Nozomi Yanagihara & Satoshi Takahashi. (2019) Analysis of major BCR-ABL1 mRNA by digital polymerase chain reaction is useful for prediction of international scale. International Journal of Clinical Oncology 24:7, pages 871-875.
Crossref
Jung Min Kim, Won Jin Kim, Mi Yeon Kim, Kwang Pyo Kim, Sang Jun Sim & Sang Kyung Kim. (2019) Development of Hydrogel Microparticle based RT-qPCR for Advanced Detection of BCR-ABL1 Transcripts. BioChip Journal 13:2, pages 182-190.
Crossref
Daniela Cilloni, Jessica Petiti, Valentina Rosso, Giacomo Andreani, Matteo Dragani, Carmen Fava & Giuseppe Saglio. (2019) Digital PCR in Myeloid Malignancies: Ready to Replace Quantitative PCR?. International Journal of Molecular Sciences 20:9, pages 2249.
Crossref
Tamara Jamaspishvili & Jeremy A. Squire. 2019. Genomic Applications in Pathology. Genomic Applications in Pathology 149 162 .
Jorge Cortes, Delphine Rea & Jeffrey H. Lipton. (2018) Treatment‐free remission with first‐ and second‐generation tyrosine kinase inhibitors. American Journal of Hematology.
Crossref
Irene Dogliotti, Daniela Drandi, Elisa Genuardi & Simone Ferrero. (2018) New Molecular Technologies for Minimal Residual Disease Evaluation in B-Cell Lymphoid Malignancies. Journal of Clinical Medicine 7:9, pages 288.
Crossref
Phenix-Lan Quan, Martin Sauzade & Eric Brouzes. (2018) dPCR: A Technology Review. Sensors 18:4, pages 1271.
Crossref
Yinlei Bai, Alberto Orfao & Chor Sang Chim. (2018) Molecular detection of minimal residual disease in multiple myeloma. British Journal of Haematology 181:1, pages 11-26.
Crossref
Yuki Koizumi, Daisuke Furuya, Teruo Endo, Kouichi Asanuma, Nozomi Yanagihara & Satoshi Takahashi. (2017) Quantification of Wilms’ tumor 1 mRNA by digital polymerase chain reaction. International Journal of Hematology 107:2, pages 230-234.
Crossref
Mary Alikian, Robert Peter Gale, Jane F Apperley & Letizia Foroni. (2017) Molecular techniques for the personalised management of patients with chronic myeloid leukaemia. Biomolecular Detection and Quantification 11, pages 4-20.
Crossref
Shuping Yu, Ming Cui, Xiao He, Rongrong Jing & Huimin Wang. (2017) A review of the challenge in measuring and standardizing BCR-ABL1. Clinical Chemistry and Laboratory Medicine (CCLM) 55:10.
Crossref
Letizia Foroni, Alistair G. Reid, Gareth Gerrard, Sarmad Toma & Sandra Hing. 2017. Dacie and Lewis Practical Haematology. Dacie and Lewis Practical Haematology 126 164 .
Justine Ellen Marum & Susan Branford. (2016) Current developments in molecular monitoring in chronic myeloid leukemia. Therapeutic Advances in Hematology 7:5, pages 237-251.
Crossref
Daniel Egan & Jerald Radich. (2016) Making the diagnosis, the tools, and risk stratification: More than just BCR-ABL. Best Practice & Research Clinical Haematology 29:3, pages 252-263.
Crossref
Daniel Egan & Jerald Radich. (2016) Monitoring disease burden in chronic myeloid leukemia: Past, present, and future. American Journal of Hematology 91:7, pages 742-746.
Crossref
Simona Soverini, Caterina De Benedittis, Manuela Mancini & Giovanni Martinelli. (2016) Present and future of molecular monitoring in chronic myeloid leukaemia. British Journal of Haematology 173:3, pages 337-349.
Crossref
Cecilia C. S. Yeung, Daniel Egan & Jerald Radich. (2016) New Methodologies in the Molecular Monitoring of CML. Current Hematologic Malignancy Reports 11:2, pages 94-101.
Crossref
Philippa C. May, Jamshid S. Khorashad, Mary Alikian, Danilo Perrotti & Alistair G. Reid. 2016. The Genetic Basis of Haematological Cancers. The Genetic Basis of Haematological Cancers 312 358 .
Aasthaa Bansal & Jerald Radich. (2016) Is cure for chronic myeloid leukemia possible in the tyrosine kinase inhibitors era?. Current Opinion in Hematology 23:2, pages 115-120.
Crossref
Mary Alikian, Peter Ellery, Martin Forbes, Gareth Gerrard, Dalia Kasperaviciute, Alona Sosinsky, Michael Mueller, Alexandra S. Whale, Dragana Milojkovic, Jane Apperley, Jim F. Huggett, Letizia Foroni & Alistair G. Reid. (2016) Next-Generation Sequencing-Assisted DNA-Based Digital PCR for a Personalized Approach to the Detection and Quantification of Residual Disease in Chronic Myeloid Leukemia Patients. The Journal of Molecular Diagnostics 18:2, pages 176-189.
Crossref
David T. Yeung & Susan Branford. 2016. Molecular Pathogenesis and Treatment of Chronic Myelogenous Leukemia. Molecular Pathogenesis and Treatment of Chronic Myelogenous Leukemia 101 129 .
Jerald Radich & Daniel Egan. 2016. Molecular Pathogenesis and Treatment of Chronic Myelogenous Leukemia. Molecular Pathogenesis and Treatment of Chronic Myelogenous Leukemia 53 67 .
Nicholas C. P. Cross & Andreas Hochhaus. 2016. Chronic Myeloid Leukemia. Chronic Myeloid Leukemia 89 98 .
Altaf Khetani, Ali Momenpour, Emilio I. Alarcon & Hanan Anis. (2015) Hollow core photonic crystal fiber for monitoring leukemia cells using surface enhanced Raman scattering (SERS). Biomedical Optics Express 6:11, pages 4599.
Crossref
Maya Koren-Michowitz, Avichai Shimoni, Filomena Daraio, Francesca Crasto, Roberta Lorenzatti, Yulia Volchek, Ninette Amariglio, Enrico Gottardi, Giuseppe Saglio & Arnon Nagler. (2015) Sensitive Replicate Real-Time Quantitative PCR of BCR-ABL Shows Deep Molecular Responses in Long-Term Post–Allogeneic Stem Cell Transplantation Chronic Myeloid Leukemia Patients. Biology of Blood and Marrow Transplantation 21:10, pages 1852-1855.
Crossref
Silvia Mori, Elisabetta Vagge, Philipp le Coutre, Elisabetta Abruzzese, Bruno Martino, Ester Pungolino, Chiara Elena, Ivana Pierri, Sarit Assouline, Anna D'Emilio, Antonella Gozzini, Pilar Giraldo, Fabio Stagno, Alessandra Iurlo, Michela Luciani, Giulia De Riso, Sara Redaelli, Dong‐Wook Kim, Alessandra Pirola, Caterina Mezzatesta, Anna Petroccione, Agnese Lodolo D'Oria, Patrizia Crivori, Rocco Piazza & Carlo Gambacorti‐Passerini. (2015) Age and d PCR can predict relapse in CML patients who discontinued imatinib: The ISAV study . American Journal of Hematology 90:10, pages 910-914.
Crossref
Xueping Chen, Li Wang, Shangchun Sheng, Teng Wang, Juan Yang, Guoming Xie & Wenli Feng. (2015) Coupling a universal DNA circuit with graphene sheets/polyaniline/AuNPs nanocomposites for the detection of BCR/ABL fusion gene. Analytica Chimica Acta 889, pages 90-97.
Crossref
Anna Grazia Recchia, Nadia Caruso, Sabrina Bossio, Mariavaleria Pellicanò, Laura De Stefano, Stefania Franzese, Angela Palummo, Vincenzo Abbadessa, Eugenio Lucia, Massimo Gentile, Ernesto Vigna, Clementina Caracciolo, Antolino Agostino, Sara Galimberti, Luciano Levato, Fabio Stagno, Stefano Molica, Bruno Martino, Paolo Vigneri, Francesco Di Raimondo & Fortunato Morabito. (2015) Flow Cytometric Immunobead Assay for Detection of BCR-ABL1 Fusion Proteins in Chronic Myleoid Leukemia: Comparison with FISH and PCR Techniques. PLOS ONE 10:6, pages e0130360.
Crossref
Daniel Egan & Jerald Radich. (2015) Prognosis and Molecular Monitoring in Chronic Myeloid Leukemia. Clinical Lymphoma Myeloma and Leukemia 15, pages S109-S113.
Crossref
N C P Cross, H E White, D Colomer, H Ehrencrona, L Foroni, E Gottardi, T Lange, T Lion, K Machova Polakova, S Dulucq, G Martinelli, E Oppliger Leibundgut, N Pallisgaard, G Barbany, T Sacha, R Talmaci, B Izzo, G Saglio, F Pane, M C Müller & A Hochhaus. (2015) Laboratory recommendations for scoring deep molecular responses following treatment for chronic myeloid leukemia. Leukemia 29:5, pages 999-1003.
Crossref
Nicholas C. P. Cross, Andreas Hochhaus & Martin C. Müller. (2015) Molecular monitoring of chronic myeloid leukemia: principles and interlaboratory standardization. Annals of Hematology 94:S2, pages 219-225.
Crossref
Paul A. Bartley, Susan Latham, Bradley Budgen, David M. Ross, Elizabeth Hughes, Susan Branford, Deborah White, Timothy P. Hughes & Alexander A. Morley. (2015) A DNA Real-Time Quantitative PCR Method Suitable for Routine Monitoring of Low Levels of Minimal Residual Disease in Chronic Myeloid Leukemia. The Journal of Molecular Diagnostics 17:2, pages 185-192.
Crossref
Fangfei Gao, Ester Pfeifer, Hassan Farah, Elena Karampini, Divyanshu Dua, Nahid Kamal, Paul Cane, Khalid Tobal, Tariq Sethi, James Spicer & Frank McCaughan. (2015) Microdroplet Digital PCR: Detection and Quantitation of Biomarkers in Archived Tissue and Serial Plasma Samples in Patients with Lung Cancer. Journal of Thoracic Oncology 10:1, pages 212-217.
Crossref
Tamara Jamaspishvili & Jeremy A. Squire. 2015. Genomic Applications in Pathology. Genomic Applications in Pathology 159 175 .
Shana O. Kelley, Chad A. Mirkin, David R. Walt, Rustem F. Ismagilov, Mehmet Toner & Edward H. Sargent. (2014) Advancing the speed, sensitivity and accuracy of biomolecular detection using multi-length-scale engineering. Nature Nanotechnology 9:12, pages 969-980.
Crossref
Luca Agnelli & Antonino Neri. (2014) Next-generation sequencing in multiple myeloma: insights into the molecular heterogeneity of the disease. International Journal of Hematologic Oncology 3:5, pages 367-376.
Crossref
David M. Ross & Timothy P. Hughes. (2014) How I determine if and when to recommend stopping tyrosine kinase inhibitor treatment for chronic myeloid leukaemia. British Journal of Haematology 166:1, pages 3-11.
Crossref
Michele BaccaraniSimona SoveriniCaterina De Benedittis. (2014) Molecular Monitoring and Mutations in Chronic Myeloid Leukemia: How to Get the Most out of Your Tyrosine Kinase Inhibitor. American Society of Clinical Oncology Educational Book:34, pages 167-175.
Crossref
Massimo Breccia & Giuliana Alimena. (2014) Discontinuation of tyrosine kinase inhibitors and new approaches to target leukemic stem cells: Treatment-free remission as a new goal in chronic myeloid leukemia. Cancer Letters 347:1, pages 22-28.
Crossref
Lawrence J. Jennings, David George, Juliann Czech, Min Yu & Loren Joseph. (2014) Detection and Quantification of BCR-ABL1 Fusion Transcripts by Droplet Digital PCR. The Journal of Molecular Diagnostics 16:2, pages 174-179.
Crossref
Simona Soverini, Gianantonio Rosti, Michele Baccarani & Giovanni Martinelli. (2014) Molecular Monitoring. Current Hematologic Malignancy Reports 9:1, pages 1-8.
Crossref
David M. RossSusan BranfordJohn F. SeymourAnthony P. SchwarerChristopher ArthurDavid T. YeungPhuong DangJarrad M. GoyneCassandra SladerRobin J. FilshieAnthony K. Mills, Junia V. MeloDeborah L. WhiteAndrew P. Grigg & Timothy P. Hughes. (2013) Safety and efficacy of imatinib cessation for CML patients with stable undetectable minimal residual disease: results from the TWISTER study. Blood 122:4, pages 515-522.
Crossref
Giuseppe Saglio & Carmen FavaManuel Sobrinho-Simões, David M Ross & Junia V Melo. 2013. The Treatment of Chronic Myeloid Leukemia. The Treatment of Chronic Myeloid Leukemia 114 128 .
Ehsan Ghayoor Karimiani & Philip Day. (2013) Personalised treatment of haematological malignancies through systems medicine based on single molecules in single cells. Integrative Biology 5:5, pages 759-767.
Crossref
Elizabeth Day, Paul H. Dear & Frank McCaughan. (2013) Digital PCR strategies in the development and analysis of molecular biomarkers for personalized medicine. Methods 59:1, pages 101-107.
Crossref
Susan Branford. (2012) Monitoring after successful therapy for chronic myeloid leukemia. Hematology 2012:1, pages 105-110.
Crossref
Junia V. Melo & David M. Ross. (2011) Minimal Residual Disease and Discontinuation of Therapy in Chronic Myeloid Leukemia: Can We Aim at a Cure?. Hematology 2011:1, pages 136-142.
Crossref
Jason E. Kreutz, Todd Munson, Toan Huynh, Feng Shen, Wenbin Du & Rustem F. Ismagilov. (2011) Theoretical Design and Analysis of Multivolume Digital Assays with Wide Dynamic Range Validated Experimentally with Microfluidic Digital PCR. Analytical Chemistry 83:21, pages 8158-8168.
Crossref
David T. Yeung, Wendy T. Parker & Susan Branford. (2011) Molecular methods in diagnosis and monitoring of haematological malignancies. Pathology 43:6, pages 566-579.
Crossref
Dong-Wook Kim. (2011) Recent advances in the path toward the cure for chronic myeloid leukemia. The Korean Journal of Hematology 46:3, pages 169.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.