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Research Article

Effect of phosphatase and tensin homology deleted on chromosome 10 (PTEN) gene transfection on reversal of multidrug resistance in K562/ADM cells

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Pages 1383-1389 | Received 27 Jun 2011, Accepted 14 Dec 2011, Published online: 31 Jan 2012

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Weipeng Zhang, Xiaowei Zheng, Ti Meng, Haisheng You, Yalin Dong, Jianfeng Xing & Siying Chen. (2017) SET protein overexpression contributes to paclitaxel resistance in MCF-7/S cells through PI3K/Akt pathway. Journal of Drug Targeting 25:3, pages 255-263.
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Annalisa Lonetti, Alessandra Cappellini, Alice Bertaina, Franco Locatelli, Andrea Pession, Francesca Buontempo, Camilla Evangelisti, Cecilia Evangelisti, Ester Orsini, Laura Zambonin, Luca Maria Neri, Alberto Maria Martelli & Francesca Chiarini. (2016) Improving nelarabine efficacy in T cell acute lymphoblastic leukemia by targeting aberrant PI3K/AKT/mTOR signaling pathway. Journal of Hematology & Oncology 9:1.
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Hong Wang, Xiu-Hong Jia, Jie-Ru Chen, Ying-Jie Yi, Jian-Yong Wang, You-Jie Li & Shu-Yang Xie. (2016) HOXB4 knockdown reverses multidrug resistance of human myelogenous leukemia K562/ADM cells by downregulating P-gp, MRP1 and BCRP expression via PI3K/Akt signaling pathway. International Journal of Oncology.
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JIE-RU CHEN, XIU-HONG JIA, HONG WANG, YING-JIE YI, JIAN-YONG WANG & YOU-JIE LI. (2016) Timosaponin A-III reverses multi-drug resistance in human chronic myelogenous leukemia K562/ADM cells via downregulation of MDR1 and MRP1 expression by inhibiting PI3K/Akt signaling pathway. International Journal of Oncology 48:5, pages 2063-2070.
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Jiangxia Cai, Siying Chen, Weipeng Zhang, Xiaowei Zheng, Sasa Hu, Chengsen Pang, Jun Lu, Jianfeng Xing & Yalin Dong. (2014) Salvianolic acid A reverses paclitaxel resistance in human breast cancer MCF-7 cells via targeting the expression of transgelin 2 and attenuating PI3 K/Akt pathway. Phytomedicine 21:12, pages 1725-1732.
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Kenneth K W To & Brian Tomlinson. (2013) Targeting the ABCG2-overexpressing multidrug resistant (MDR) cancer cells by PPARγ agonists. British Journal of Pharmacology 170:5, pages 1137-1151.
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