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Research Article

Decreased 5-hydroxymethylcytosine levels are associated with TET2 mutation and unfavorable overall survival in myelodysplastic syndromes

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Pages 2466-2473 | Received 19 Dec 2012, Accepted 16 Feb 2013, Published online: 27 Mar 2013

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Xiaoli Wang, Tao Guo, Shanshan Wang, Xiangfeng Chen, Yue Chen, Jinpeng Yuan & Rusong Zhao. (2017) Determination of 5-hydroxymethyl-2′-deoxycytidine in Rice by High-performance Liquid Chromatography–Tandem Mass Spectrometry with Isotope Dilution. Analytical Letters 50:15, pages 2351-2358.
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Jianming Shao, Shilpan Shah, Siddhartha Ganguly, Youli Zu, Chuan He & Zejuan Li. (2023) Classification of Acute Myeloid Leukemia by Cell-Free DNA 5-Hydroxymethylcytosine. Genes 14:6, pages 1180.
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Ryujiro Hara, Toshihiko Kitahara, Hiroki Numata, Masako Toyosaki, Shigeki Watanabe, Eri Kikkawa, Yoshiaki Ogawa, Hiroshi Kawada & Kiyoshi Ando. (2022) Fetal hemoglobin level predicts lower-risk myelodysplastic syndrome. International Journal of Hematology 117:5, pages 684-693.
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Lingxu Jiang, Yingwan Luo, Shuanghong Zhu, Lu Wang, Liya Ma, Hua Zhang, Chuying Shen, Wenli Yang, Yanling Ren, Xinping Zhou, Chen Mei, Li Ye, Weilai Xu, Haiyang Yang, Chenxi Lu, Jie Jin & Hongyan Tong. (2019) Mutation status and burden can improve prognostic prediction of patients with lower‐risk myelodysplastic syndromes. Cancer Science 111:2, pages 580-591.
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Ping Zhang, Wen‐Wen Weng, Ping Chen, Yao Zhang, Jin‐Fei Ruan, Dian‐Dian Ba, Wei‐Qun Xu & Yong‐Min Tang. (2019) Low expression of TET2 gene in pediatric acute lymphoblastic leukemia is associated with poor clinical outcome . International Journal of Laboratory Hematology 41:5, pages 702-709.
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Mengying Tong, Shuhang Gao, Wenjing Qi, Chang Shi, Meng Qiu, Fang Yang, Shanshan Bai, Husha Li, Zhizhou Wang, Zhigang Sun, Lina Wang & Ying Che. (2019) 5‑Hydroxymethylcytosine as a potential epigenetic biomarker in papillary thyroid carcinoma. Oncology Letters.
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Fang Ye & Ningning Li. (2019) Role of p15(INK4B) Methylation in Patients With Myelodysplastic Syndromes: A Systematic Meta-Analysis. Clinical Lymphoma Myeloma and Leukemia 19:6, pages e259-e265.
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Maki Ohya, Koh Nakazawa & Hiroyuki Kanno. (2019) Lower number of 5-hydroxymethylcytosine-expressing cells in plasma cell myeloma than in reactive plasma cell hyperplasia: a useful immunohistochemical approach for identification of neoplastic plasma cells. Pathology 51:1, pages 81-85.
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Fabrizio Simeoni & Tim C.P. Somervaille. (2018) Revert the SIRT: Normalizing SIRT1 Activity in Myelodysplastic Stem Cells. Cell Stem Cell 23:3, pages 315-317.
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Zhen Guo, Shao-kai Zhang, Zhe Zou, Rui-hua Fan & Xiao-dong Lyu. (2017) Prognostic significance of TET2 mutations in myelodysplastic syndromes: A meta-analysis. Leukemia Research 58, pages 102-107.
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Yun Lin, Zhijuan Lin, Kun Cheng, Zhihong Fang, Zhifeng Li, Yiming Luo & Bing Xu. (2017) Prognostic role of TET2 deficiency in myelodysplastic syndromes: A meta-analysis . Oncotarget 8:26, pages 43295-43305.
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Olesya Pavlova, Sylvie Fraitag & Daniel Hohl. (2016) 5-Hydroxymethylcytosine Expression in Proliferative Nodules Arising within Congenital Nevi Allows Differentiation from Malignant Melanoma. Journal of Investigative Dermatology 136:12, pages 2453-2461.
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Manuel Buscarlet, Alain Tessier, Sylvie Provost, Luigina Mollica & Lambert Busque. (2016) Human blood cell levels of 5-hydroxymethylcytosine (5hmC) decline with age, partly related to acquired mutations in TET2. Experimental Hematology 44:11, pages 1072-1084.
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T. Gambichler, K. Mamali, N. Patsinakidis, R. Moritz, M. Mucke, M. Skrygan, E. Stockfleth & M. Stücker. (2016) Decreased expression of ten-eleven translocation 2 protein is associated with progressive disease and death in patients with mycosis fungoides. British Journal of Dermatology 174:3, pages 652-653.
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