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Hima V. Vangapandu, Huiqin Chen, William G. Wierda, Michael J. Keating, Anil Korkut & Varsha Gandhi. (2018) Proteomics profiling identifies induction of caveolin-1 in chronic lymphocytic leukemia cells by bone marrow stromal cells. Leukemia & Lymphoma 59:6, pages 1427-1438.
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Andrew Aw & Jennifer R. Brown. (2017) The potential combination of BCL-2 inhibitors and ibrutinib as frontline therapy in chronic lymphocytic leukemia. Leukemia & Lymphoma 58:10, pages 2287-2297.
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Ying Wu, Patricia M. A. Zehnle, Jovana Rajak, Naile Koleci, Geoffroy Andrieux, Lorena Gallego-Villar, Konrad Aumann, Melanie Boerries, Charlotte M. Niemeyer, Christian Flotho, Sheila Bohler & Miriam Erlacher. (2023) BH3 mimetics and azacitidine show synergistic effects on juvenile myelomonocytic leukemia. Leukemia.
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Nathan Dubois, Emerence Crompot, Nathalie Meuleman, Dominique Bron, Laurence Lagneaux & Basile Stamatopoulos. (2020) Importance of Crosstalk Between Chronic Lymphocytic Leukemia Cells and the Stromal Microenvironment: Direct Contact, Soluble Factors, and Extracellular Vesicles. Frontiers in Oncology 10.
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Xue Yi, Aloke Sarkar, Gorkem Kismali, Burcu Aslan, Mary Ayres, LaKesla R. Iles, Michael J. Keating, William G. Wierda, James P. Long, Maria Teresa Sabrina Bertilaccio & Varsha Gandhi. (2020) AMG-176, an Mcl-1 Antagonist, Shows Preclinical Efficacy in Chronic Lymphocytic Leukemia. Clinical Cancer Research 26:14, pages 3856-3867.
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Maurizio Mangolini & Ingo Ringshausen. (2020) Bone Marrow Stromal Cells Drive Key Hallmarks of B Cell Malignancies. International Journal of Molecular Sciences 21:4, pages 1466.
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Marilena Ciciarello, Giulia Corradi, Federica Loscocco, Giuseppe Visani, Federica Monaco, Michele Cavo, Antonio Curti & Alessandro Isidori. (2019) The Yin and Yang of the Bone Marrow Microenvironment: Pros and Cons of Mesenchymal Stromal Cells in Acute Myeloid Leukemia. Frontiers in Oncology 9.
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Fabiola Cervantes-Gomez, Christine M. Stellrecht, Mary L. Ayres, Michael J. Keating, William G. Wierda & Varsha Gandhi. (2019) PIM kinase inhibitor, AZD1208, inhibits protein translation and induces autophagy in primary chronic lymphocytic leukemia cells. Oncotarget 10:29, pages 2793-2809.
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Alessio Montresor, Lara Toffali, Antonella Rigo, Isacco Ferrarini, Fabrizio Vinante & Carlo Laudanna. (2018) CXCR4- and BCR-triggered integrin activation in B-cell chronic lymphocytic leukemia cells depends on JAK2-activated Bruton’s tyrosine kinase. Oncotarget 9:80, pages 35123-35140.
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Maurizio Mangolini, Frederik Götte, Andrew Moore, Tim Ammon, Madlen Oelsner, Gloria Lutzny-Geier, Ludger Klein-Hitpass, James C. Williamson, Paul J. Lehner, Jan Dürig, Michael Möllmann, Lívia Rásó-Barnett, Katherine Hughes, Antonella Santoro, Simón Méndez-Ferrer, Robert A. J. Oostendorp, Ursula Zimber-Strobl, Christian Peschel, Daniel J. Hodson, Marc Schmidt-Supprian & Ingo Ringshausen. (2018) Notch2 controls non-autonomous Wnt-signalling in chronic lymphocytic leukaemia. Nature Communications 9:1.
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Hima V. Vangapandu, Mary L. Ayres, Christopher A. Bristow, William G. Wierda, Michael J. Keating, Kumudha Balakrishnan, Christine M. Stellrecht & Varsha Gandhi. (2017) The Stromal Microenvironment Modulates Mitochondrial Oxidative Phosphorylation in Chronic Lymphocytic Leukemia Cells. Neoplasia 19:10, pages 762-771.
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V M Patel, K Balakrishnan, M Douglas, T Tibbitts, E Y Xu, J L Kutok, M Ayers, A Sarkar, R Guerrieri, W G Wierda, S O'Brien, N Jain, H M Stern & V Gandhi. (2017) Duvelisib treatment is associated with altered expression of apoptotic regulators that helps in sensitization of chronic lymphocytic leukemia cells to venetoclax (ABT-199). Leukemia 31:9, pages 1872-1881.
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Betty Lamothe, William G. Wierda, Michael J. Keating & Varsha Gandhi. (2016) Carfilzomib Triggers Cell Death in Chronic Lymphocytic Leukemia by Inducing Proapoptotic and Endoplasmic Reticulum Stress Responses. Clinical Cancer Research 22:18, pages 4712-4726.
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Michael Y. Choi, Manoj Kumar Kashyap & Deepak Kumar. (2016) The chronic lymphocytic leukemia microenvironment: Beyond the B-cell receptor. Best Practice & Research Clinical Haematology 29:1, pages 40-53.
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Viralkumar Patel, Kumudha BalakrishnanMichael J. Keating, William G. Wierda & Varsha Gandhi. (2015) Expression of executioner procaspases and their activation by a procaspase-activating compound in chronic lymphocytic leukemia cells. Blood 125:7, pages 1126-1136.
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Betty Lamothe, Fabiola Cervantes-Gomez, Mariela Sivina, William G. Wierda, Michael J. Keating & Varsha Gandhi. (2015) Proteasome inhibitor carfilzomib complements ibrutinib’s action in chronic lymphocytic leukemia. Blood 125:2, pages 407-410.
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Viralkumar Patel, Kumudha Balakrishnan & Varsha Gandhi. 2015. Multi-Targeted Approach to Treatment of Cancer. Multi-Targeted Approach to Treatment of Cancer
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Kumudha Balakrishnan, Jan A. Burger, Min Fu, Tejaswini Doifode, William G. Wierda & Varsha Gandhi. (2014) Regulation of Mcl-1 Expression in Context to Bone Marrow Stromal Microenvironment in Chronic Lymphocytic Leukemia. Neoplasia 16:12, pages 1036-1046.
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