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Leukemia & Lymphoma Volume 56, 2015 - Issue 6
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Original Article: Clinical

Lenalidomide monotherapy in heavily pretreated patients with non-Hodgkin lymphoma: an Italian observational multicenter retrospective study in daily clinical practice

Pier Luigi ZinzaniInstitute of Haematology “L. e A. Seràgnoli”, University of Bologna, ItalyCorrespondence[email protected]
,
Luigi RigacciDepartment of Hematology, “Careggi” Hospital, Firenze, Italy
,
Maria Cristina CoxHematology Unit, AO Sant’Andrea, Department of Clinical and Experimental Medicine, La Sapienza University, Roma, Italy
,
Liliana DevizziMedical Oncology 2, National Cancer Institute, Milano, Italy
,
Alberto FabbriDivision of Hematology, “S.Maria alle Scotte” Hospital, Siena, Italy
,
Alfonso ZaccariaUO Haematology, S.Maria delle Croci Hospital, Ravenna, Italy
,
Francesco ZajaHematology, DISM, AOUD S. M. Misericordia, Udine, Italy
,
Alice Di RoccoDepartment of Cellular Biotechnologies and Hematology, “Sapienza” University, Roma, Italy
,
Giuseppe RossiDepartment of Hematology, Spedali Civili, Brescia, Italy
,
Sergio StortiCenter for High Technology Research and Education in Biomedical Sciences, University “Cattolica del Sacro Cuore”, Campobasso, Italy
,
Pier Paolo FattoriIstituto Scientifico Romagnolo per lo studio e la Cura dei Tumori (IRST) S.r.l. IRCCS, Meldola, Italy
,
Lisa ArgnaniInstitute of Haematology “L. e A. Seràgnoli”, University of Bologna, Italy
,
Sante TuraInstitute of Haematology “L. e A. Seràgnoli”, University of Bologna, Italy
&
Umberto VitoloAO Città della Salute e della Scienza di Torino, Torino, Italy
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Pages 1671-1676 | Received 17 Mar 2014, Accepted 07 Sep 2014, Published online: 19 Nov 2014

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Pier Luigi Zinzani, Luigi Rigacci, Maria Cristina Cox, Liliana Devizzi, Alberto Fabbri, Francesco Zaja, Alice Di Rocco, Giuseppe Rossi, Sergio Storti, Pier Paolo Fattori, Lisa Argnani & Umberto Vitolo. (2017) The efficacy of lenalidomide combination therapy in heavily pretreated non-Hodgkin lymphoma patients: an Italian observational, multicenter, retrospective study. Leukemia & Lymphoma 58:1, pages 226-229.
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Sylvain Garciaz, Diane Coso, Jean-Marc Schiano de Colella & Réda Bouabdallah. (2016) Lenalidomide for the treatment of B-cell lymphoma. Expert Opinion on Investigational Drugs 25:9, pages 1103-1116.
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Ayse Salihoglu, Muhlis Cem Ar & Teoman Soysal. (2015) Novelties in the management of B-cell malignancies: B-cell receptor signaling inhibitors and lenalidomide. Expert Review of Hematology 8:6, pages 765-783.
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David Belada, Katerina Kopeckova, Juan Miguel Bergua Burgues, Don Stevens, Marc André, Ernesto Perez Persona, Petra Pichler, Philipp B. Staber, Marek Trneny, Johannes Duell, Maeve Waldron-Lynch, Steve Wagner, Amitava Mukhopadhyay, Maren Dirnberger-Hertweck, John M. Burke & Grzegorz S. Nowakowski. (2023) Safety and efficacy of tafasitamab with or without lenalidomide added to first-line R-CHOP for DLBCL: the phase 1b First-MIND study. Blood 142:16, pages 1348-1358.
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Reyad Dada. (2023) Redefining Precision Management of r/r Large B-Cell Lymphoma: Novel Antibodies Take on CART and BMT in the Quest for Future Treatment Strategies. Cells 12:14, pages 1858.
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Jia Li, Jianpeng Zhou, Wei Guo, Xingtong Wang, Yangzhi Zhao & Ou Bai. (2021) Efficacy and Safety of Lenalidomide Monotherapy for Relapsed/Refractory Diffuse Large B Cell Lymphoma: Systematic Review and Meta-Analysis. Frontiers in Oncology 11.
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Johannes Duell, Kami J. Maddocks, Eva González-Barca, Wojciech Jurczak, Anna Marina Liberati, Sven De Vos, Zsolt Nagy, Aleš Obr, Gianluca Gaidano, Pau Abrisqueta, Nagesh Kalakonda, Marc André, Martin Dreyling, Tobias Menne, Olivier Tournilhac, Marinela Augustin, Andreas Rosenwald, Maren Dirnberger-Hertweck, Johannes Weirather, Sumeet Ambarkhane & Gilles Salles. (2021) Long-term outcomes from the Phase II L-MIND study of tafasitamab (MOR208) plus lenalidomide in patients with relapsed or refractory diffuse large B-cell lymphoma. Haematologica 106:9, pages 2417-2426.
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Chenggong Li, Yan Sun, Jing Wang, Lu Tang, Huiwen Jiang, Tao Guo, Lin Liu, Yaohui Wu, Lisha Ai, Linghui Xia, Jianjun Wu, Zhicai Lin, Qijun Qian, Yu Hu & Heng Mei. (2021) PiggyBac-Generated CAR19-T Cells Plus Lenalidomide Cause Durable Complete Remission of Triple-Hit Refractory/Relapsed DLBCL: A Case Report. Frontiers in Immunology 12.
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Emily C. Ayers, David Margolis & Daniel J. Landsburg. (2020) Real World Outcomes in Patients With Relapsed/Refractory Diffuse Large B-cell Lymphoma Receiving Palliative Intent Therapies. Clinical Lymphoma Myeloma and Leukemia 20:10, pages 661-667.
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Alessandro Broccoli, Beatrice Casadei, Annalisa Chiappella, Carlo Visco, Monica Tani, Nicola Cascavilla, Annarita Conconi, Monica Balzarotti, Maria Christina Cox, Dario Marino, Maria Cecilia Goldaniga, Roberto Marasca, Cristina Tecchio, Caterina Patti, Gerardo Musuraca, Liliana Devizzi, Federico Monaco, Alessandra Romano, Angelo Fama, Michelle Zancanella, Rossella Paolini, Luigi Rigacci, Claudia Castellino, Francesco Gaudio, Lisa Argnani & Pier Luigi Zinzani. (2019) Lenalidomide in Pretreated Patients with Diffuse Large B-Cell Lymphoma: An Italian Observational Multicenter Retrospective Study in Daily Clinical Practice. The Oncologist 24:9, pages 1246-1252.
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Li-Yangxue Ma & Li Su. (2018) Application of Lenalidomide on Diffused Large B-cell Lymphoma. Chinese Medical Journal 131:20, pages 2510-2513.
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Vittorio Stefoni, Cinzia Pellegrini, Alessandro Broccoli, Luca Baldini, Monica Tani, Emanuele Cencini, Amalia Figuera, Michela Ansuinelli, Elisa Bernocco, Maria Cantonetti, Maria Christina Cox, Filippo Ballerini, Chiara Rusconi, Carlo Visco, Luca Arcaini, Angelo Fama, Roberto Marasca, Stefano Volpetti, Alessia Castellino, Catello Califano, Marina Cavaliere, Guido Gini, Anna Marina Liberati, Gerardo Musuraca, Anna Lucania, Giuseppina Ricciuti, Lisa Argnani & Pier Luigi Zinzani. (2018) Lenalidomide in Pretreated Mantle Cell Lymphoma Patients: An Italian Observational Multicenter Retrospective Study in Daily Clinical Practice (the Lenamant Study). The Oncologist 23:9, pages 1033-1038.
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Christian Gisselbrecht & Eric Van Den Neste. (2018) How I manage patients with relapsed/refractory diffuse large B cell lymphoma. British Journal of Haematology 182:5, pages 633-643.
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Marie Beylot-Barry, Diane Mermin, Aline Maillard, Reda Bouabdallah, Nathalie Bonnet, Anne-Bénédicte Duval-Modeste, Laurent Mortier, Saskia Ingen-Housz-Oro, Caroline Ram-Wolff, Stéphane Barete, Stéphane Dalle, Eve Maubec, Gaelle Quereux, Isabelle Templier, Martine Bagot, Florent Grange, Pascal Joly, Béatrice Vergier, Pierre-Julien Vially, Audrey Gros, Anne Pham-Ledard, Eric Frison & Jean-Philippe Merlio. (2018) A Single-Arm Phase II Trial of Lenalidomide in Relapsing or Refractory Primary Cutaneous Large B-Cell Lymphoma, Leg Type. Journal of Investigative Dermatology 138:9, pages 1982-1989.
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G. Iacoboni, E. Zucca, M. Ghielmini & A. Stathis. (2018) Methodology of clinical trials evaluating the incorporation of new drugs in the first-line treatment of patients with diffuse large B-cell lymphoma (DLBCL): a critical review. Annals of Oncology 29:5, pages 1120-1129.
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Massimiliano Salati, Vittoria Tarantino, Antonino Maiorana, Stefania Bettelli & Stefano Luminari. (2017) Durable remission in a patient with leptomeningeal relapse of a MYC/BCL6-positive double-hit DLBCL treated with lenalidomide monotherapy. Hematological Oncology 35:4, pages 861-863.
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Lisa Argnani & Pier Luigi Zinzani. (2017) Reporting real-life experience with drugs in lymphoma patients. Hematological Oncology 35:4, pages 909-910.
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Patrizia Mondello, Normann Steiner, Wolfgang Willenbacher, Simone Ferrero, Paola Ghione, Alessandra Marabese, Vincenzo Pitini, Salvatore Cuzzocrea & Michael Mian. (2016) Lenalidomide in Relapsed or Refractory Diffuse Large B-Cell Lymphoma: Is It a Valid Treatment Option?. The Oncologist 21:9, pages 1107-1112.
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