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Original Article: Research

Activation of p53-dependent/-independent pathways of apoptotic cell death by chelerythrine in a murine T cell lymphoma

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Pages 1846-1855 | Received 24 Apr 2014, Accepted 28 Sep 2014, Published online: 08 Jan 2015

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Munendra Singh Tomar, Sanjay Kumar, Sanjay Kumar, Pramod Kumar Gautam, Rishi Kant Singh, Praveen Kumar Verma, Surya Pratap Singh & Arbind Acharya. (2018) NK Cell Effector Functions Regulation by Modulating nTreg Cell Population During Progressive Growth of Dalton’s Lymphoma in Mice. Immunological Investigations 47:1, pages 40-56.
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Yuxin Shi, Lei Li, Chuansen Wang, Jing Huang, Lixin Feng, Xiqiang Chen, Attila Gabor SIK, Kechun Liu, Meng Jin & Rongchun Wang. (2023) Developmental toxicity induced by chelerythrine in zebrafish embryos via activating oxidative stress and apoptosis pathways. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology 273, pages 109719.
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Xin Yang, Limin Ma, Hongwei Shao, Zikai Zhou, Xia Ling, Mengyu Yao, Guowen Luo, Stefano Scoditti, Emilia Sicilia, Gloria Mazzone, Meng Gao & Ben Zhong Tang. (2022) Riboflavin-Promoted In Situ Photoactivation of Dihydroalkaloid Prodrugs for Cancer Therapy. Journal of Medicinal Chemistry 65:23, pages 15738-15748.
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Nianzhi Chen, Yulin Qi, Xiao Ma, Xiaolin Xiao, Qingsong Liu, Ting Xia, Juyi Xiang, Jinhao Zeng & Jianyuan Tang. (2022) Rediscovery of Traditional Plant Medicine: An Underestimated Anticancer Drug of Chelerythrine. Frontiers in Pharmacology 13.
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Kai Kang, Hanbing Jiang, Shujun Zhang & Binglin Cheng. (2022) Antitumor Effects of Chelerythrine: A Literature Review. Natural Product Communications 17:6, pages 1934578X2211030.
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Mingwei Zhu, Jiamei Niu, Jian Jiang, Tianxiu Dong, Yaodong Chen, Xiuhua Yang & Pengfei Liu. (2022) Chelerythrine inhibits the progression of glioblastoma by suppressing the TGFB1-ERK1/2/Smad2/3-Snail/ZEB1 signaling pathway. Life Sciences 293, pages 120358.
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Sidhali U. Parsekar, Priyanka Velankanni, Shruti Sridhar, Paramita Haldar, Nayan A. Mate, Arnab Banerjee, P. K. Sudhadevi Antharjanam, Aditya P. Koley & Manjuri Kumar. (2020) Protein binding studies with human serum albumin, molecular docking and in vitro cytotoxicity studies using HeLa cervical carcinoma cells of Cu( ii )/Zn( ii ) complexes containing a carbohydrazone ligand . Dalton Transactions 49:9, pages 2947-2965.
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Po‐Hsiang Chen, Yi‐Tung Chen, Tai‐Ying Chu, Tian‐Hsiang Ma, Mei‐Hsuan Wu, Hsi‐Hsien Lin, Yu‐Sun Chang, Bertrand Chin‐Ming Tan & Szecheng J. Lo. (2019) Nucleolar control by a non‐apoptotic p53‐caspases‐deubiquitinylase axis promotes resistance to bacterial infection. The FASEB Journal 34:1, pages 1107-1121.
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Alaa El-Din H. Sayed, Ahmed M. Kotb, Shoji Oda, Shosaku Kashiwada & Hiroshi Mitani. (2019) Protective effect of p53 knockout on 4-nonylphenol-induced nephrotoxicity in medaka (Oryzias latipes). Chemosphere 236, pages 124314.
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E Eluka-Okoludoh, AJ Ewunkem, S Thorpe, A Blanchard & P Muganda. (2018) Diepoxybutane-induced apoptosis is mediated through the ERK1/2 pathway. Human & Experimental Toxicology 37:10, pages 1080-1091.
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Wanjun Lin, Jiajun Huang, Zhongwen Yuan, Senling Feng, Ying Xie & Wenzhe Ma. (2017) Protein kinase C inhibitor chelerythrine selectively inhibits proliferation of triple-negative breast cancer cells. Scientific Reports 7:1.
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