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A phase II study of AT9283, an aurora kinase inhibitor, in patients with relapsed or refractory multiple myeloma: NCIC clinical trials group IND.191

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Xue-Li Jing & Shi-Wu Chen. (2021) Aurora kinase inhibitors: a patent review (2014-2020). Expert Opinion on Therapeutic Patents 31:7, pages 625-643.
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Wenxiang Bai, Honghua Wang & Hua Bai. (2019) Identification of Candidate Genes and Therapeutic Agents for Light Chain Amyloidosis Based on Bioinformatics Approach. Pharmacogenomics and Personalized Medicine 12, pages 387-396.
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Judith Lind, Felix Czernilofsky, Sonia Vallet & Klaus Podar. (2019) Emerging protein kinase inhibitors for the treatment of multiple myeloma. Expert Opinion on Emerging Drugs 24:3, pages 133-152.
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Konstantinos Mintzas & Michael Heuser. (2019) Emerging strategies to target the dysfunctional cohesin complex in cancer. Expert Opinion on Therapeutic Targets 23:6, pages 525-537.
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Articles from other publishers (16)

Antal H. Kovacs, Dong Zhao & Jinqiang Hou. (2023) Aurora B Inhibitors as Cancer Therapeutics. Molecules 28:8, pages 3385.
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Su Jeong Kim, Min Yeong Choi, Keun Young Min, Min Geun Jo, Jie Min Kim, Hyung Sik Kim & Young Mi Kim. (2022) AT9283, 1-Cyclopropyl-3-(3-(5-(Morpholinomethyl)-1H-Benzo[d]Imidazole-2-yl)-1H-Pyrazol-4-yl) Urea, Inhibits Syk to Suppress Mast Cell-Mediated Allergic Response. Biomolecules & Therapeutics 30:6, pages 520-528.
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Hongmei Jiang, Yixuan Wang, Jingjing Wang, Yafei Wang, Sheng Wang, Enyang He, Jing Guo, Ying Xie, Jingya Wang, Xin Li, Ziyi Peng, Mengqi Wang, Jian Hou & Zhiqiang Liu. (2022) Posttranslational modification of Aurora A‐NSD2 loop contributes to drug resistance in t(4;14) multiple myeloma. Clinical and Translational Medicine 12:4.
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Ruijuan Du, Chuntian Huang, Kangdong Liu, Xiang Li & Zigang Dong. (2021) Targeting AURKA in Cancer: molecular mechanisms and opportunities for Cancer therapy. Molecular Cancer 20:1.
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Azaj Ahmed, Anas Shamsi, Taj Mohammad, Gulam Mustafa Hasan, Asimul Islam & Md. Imtaiyaz Hassan. (2021) Aurora B kinase: a potential drug target for cancer therapy. Journal of Cancer Research and Clinical Oncology 147:8, pages 2187-2198.
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Kaksha Sankhe, Arati Prabhu & Tabassum Khan. (2021) Design strategies, SAR, and mechanistic insight of Aurora kinase inhibitors in cancer. Chemical Biology & Drug Design 98:1, pages 73-93.
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Naheed Arfin Borah & Mamatha M. Reddy. (2021) Aurora Kinase B Inhibition: A Potential Therapeutic Strategy for Cancer. Molecules 26:7, pages 1981.
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Laura Torrente, Gunjit Maan, Asma Oumkaltoum Rezig, Jean Quinn, Angus Jackson, Andrea Grilli, Laura Casares, Ying Zhang, Evgeny Kulesskiy, Jani Saarela, Silvio Bicciato, Joanne Edwards, Albena T. Dinkova-Kostova & Laureano de la Vega. (2020) High NRF2 Levels Correlate with Poor Prognosis in Colorectal Cancer Patients and with Sensitivity to the Kinase Inhibitor AT9283 In Vitro. Biomolecules 10:10, pages 1365.
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Justus M. Huelse, Diana M. Fridlyand, Shelton Earp, Deborah DeRyckere & Douglas K. Graham. (2020) MERTK in cancer therapy: Targeting the receptor tyrosine kinase in tumor cells and the immune system. Pharmacology & Therapeutics 213, pages 107577.
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Hemant Arya & Mohane Selvaraj Coumar. (2020) Design of novel ROCK inhibitors using fragment-based de novo drug design approach. Journal of Molecular Modeling 26:9.
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Meral Beksac, Sevinc Balli & Dilara Akcora Yildiz. (2020) Drug Targeting of Genomic Instability in Multiple Myeloma. Frontiers in Genetics 11.
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Xinran Liu, Yuchen Chen, Yangkai Li, Robert B. Petersen & Kun Huang. (2019) Targeting mitosis exit: A brake for cancer cell proliferation. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 1871:1, pages 179-191.
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Emira Bousoik & Hamidreza Montazeri Aliabadi. (2018) “Do We Know Jack” About JAK? A Closer Look at JAK/STAT Signaling Pathway. Frontiers in Oncology 8.
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Cornelis J. Korbee, Matthias T. Heemskerk, Dragi Kocev, Elisabeth van Strijen, Omid Rabiee, Kees L. M. C. Franken, Louis Wilson, Nigel D. L. Savage, Sašo Džeroski, Mariëlle C. Haks & Tom H. M. Ottenhoff. (2018) Combined chemical genetics and data-driven bioinformatics approach identifies receptor tyrosine kinase inhibitors as host-directed antimicrobials. Nature Communications 9:1.
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Anke Maes, Eline Menu, Kim De Veirman, Ken Maes, Karin Vanderkerken & Elke De Bruyne. (2017) The therapeutic potential of cell cycle targeting in multiple myeloma. Oncotarget 8:52, pages 90501-90520.
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Jonas Cicenas & Erikas Cicenas. (2016) Multi-kinase inhibitors, AURKs and cancer. Medical Oncology 33:5.
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