Advanced search
Publication Cover
Leukemia & Lymphoma Volume 57, 2016 - Issue 11
Submit an article Journal homepage
669
Views
11
CrossRef citations to date
0
Altmetric
Original Articles: Research

Characteristics of BCR-ABL kinase domain mutations in chronic myeloid leukemia from India: not just missense mutations but insertions and deletions are also associated with TKI resistance

Nikhil PatkarHematopathology Laboratory, Tata Memorial Centre, Ernest Borges Marg, Parel, Mumbai, Maharashtra, India;
,
Kiran GhodkeHematopathology Laboratory, Tata Memorial Centre, Ernest Borges Marg, Parel, Mumbai, Maharashtra, India;
,
Swapnali JoshiHematopathology Laboratory, Tata Memorial Centre, Ernest Borges Marg, Parel, Mumbai, Maharashtra, India;
,
Shruti ChaudharyHematopathology Laboratory, Tata Memorial Centre, Ernest Borges Marg, Parel, Mumbai, Maharashtra, India;
,
Russel MascerhenasHematopathology Laboratory, Tata Memorial Centre, Ernest Borges Marg, Parel, Mumbai, Maharashtra, India;
,
Sona DussejaHematopathology Laboratory, Tata Memorial Centre, Ernest Borges Marg, Parel, Mumbai, Maharashtra, India;
,
Shashikant MahadikHematopathology Laboratory, Tata Memorial Centre, Ernest Borges Marg, Parel, Mumbai, Maharashtra, India;
,
Sheetal GawareHematopathology Laboratory, Tata Memorial Centre, Ernest Borges Marg, Parel, Mumbai, Maharashtra, India;
,
Prashant TembhareHematopathology Laboratory, Tata Memorial Centre, Ernest Borges Marg, Parel, Mumbai, Maharashtra, India;
,
Sumeet GujralHematopathology Laboratory, Tata Memorial Centre, Ernest Borges Marg, Parel, Mumbai, Maharashtra, India;
,
Sharayu KabreDepartment of Cancer Cytogenetics, Tata Memorial Centre, Ernest Borges Marg, Parel, Mumbai, Maharashtra, India;
,
Pratibha Kadam-AmareDepartment of Cancer Cytogenetics, Tata Memorial Centre, Ernest Borges Marg, Parel, Mumbai, Maharashtra, India;
,
Hasmukh JainAdult Haemato-lymphoid Disease Management Group, Tata Memorial Centre, Ernest Borges Marg, Parel, Mumbai, Maharashtra, India;
,
Uma DangiAdult Haemato-lymphoid Disease Management Group, Tata Memorial Centre, Ernest Borges Marg, Parel, Mumbai, Maharashtra, India;
,
Bhausaheb BagalAdult Haemato-lymphoid Disease Management Group, Tata Memorial Centre, Ernest Borges Marg, Parel, Mumbai, Maharashtra, India;
,
Navin KhattryAdult Haemato-lymphoid Disease Management Group, Tata Memorial Centre, Ernest Borges Marg, Parel, Mumbai, Maharashtra, India;
,
Manju SengarAdult Haemato-lymphoid Disease Management Group, Tata Memorial Centre, Ernest Borges Marg, Parel, Mumbai, Maharashtra, India;
,
Brijesh AroraPediatric Haemato-lymphoid Disease Management Group, Tata Memorial Centre, Ernest Borges Marg, Parel, Mumbai, Maharashtra, India
,
Gaurav NarulaPediatric Haemato-lymphoid Disease Management Group, Tata Memorial Centre, Ernest Borges Marg, Parel, Mumbai, Maharashtra, India
,
Shripad BanavaliPediatric Haemato-lymphoid Disease Management Group, Tata Memorial Centre, Ernest Borges Marg, Parel, Mumbai, Maharashtra, India
,
Hari MenonAdult Haemato-lymphoid Disease Management Group, Tata Memorial Centre, Ernest Borges Marg, Parel, Mumbai, Maharashtra, India;
&
Papagudi Ganesan SubramanianHematopathology Laboratory, Tata Memorial Centre, Ernest Borges Marg, Parel, Mumbai, Maharashtra, India; Correspondence[email protected]
 show all
Pages 2653-2660 | Received 16 Sep 2015, Accepted 14 Feb 2016, Published online: 21 Mar 2016

Citations (11)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (1)

Priyavadhana Balasubramanian, Anita Chopra, Deepak Verma, Indresh K. Singh, Akash Kumar, Atul Sharma & Rajive Kumar. (2017) Imatinib resistance in chronic myeloid leukemia due to a rare mutation. Leukemia & Lymphoma 58:7, pages 1750-1752.
Read now

Articles from other publishers (10)

Deepak Kumar Mishra, Indranil Dey, Rakesh Demde, Sushant Vinarkar & Mayur Parihar. (2023) Disease Response Assessment Modalities in Chronic Myeloid Leukemia: Past, Present, and Future. Indian Journal of Medical and Paediatric Oncology 44:06, pages 592-601.
Crossref
Caryn Benjamin, Stephanie Murugan, Siddeeq Hoosen & Nadine Rapiti. (2023) Chronic myeloid leukemia kinase domain mutations: A retrospective descriptive study on the therapeutic and prognostic significance in patients at King Edward VIII Hospital, KwaZulu‐Natal, South Africa. Health Science Reports 6:7.
Crossref
Atreye Majumdar, Rahul Katara, Avshesh Mishra, Aastha Gupta, Deepak K. Sharma, Aman K. Srivastava, Shivani Sharma, Ankita Jaiswal, Mallika Dixit, Vipin Kumar, Sachin Kumar, Varun Kumar, Rahul Sharma & Sambit K. Mohanty. (2022) A Retrospective Analysis of BCR-ABL1 Kinase Domain Mutations in the Frontline Drug Intolerant or Resistant Chronic Myeloid Leukemia Patients: An Indian Experience from a High-End Referral Laboratory. South Asian Journal of Cancer.
Crossref
K Ghosh. (2022) Tyrosine kinase domain mutations in chronic myelogenous leukemia patients: Indian perspective. Journal of Postgraduate Medicine 68:2, pages 70.
Crossref
Fisihatsion Tadesse, Getahun Asres, Abdulaziz Abubeker, Amha Gebremedhin & Jerald Radich. (2021) Spectrum of BCR-ABL Mutations and Treatment Outcomes in Ethiopian Imatinib-Resistant Patients With Chronic Myeloid Leukemia. JCO Global Oncology:7, pages 1187-1193.
Crossref
Sheng‐Hsuan Chien, Hsueng‐Mei Liu, Po‐Ming Chen, Po‐Shen Ko, Jeong‐Shi Lin, Ying‐Ju Chen, Li‐Hsuan Lee, Liang‐Tsai Hsiao, Tzeon‐Jye Chiou, Jyh‐Pyng Gau, Muh‐Hwa Yang & Chun‐Yu Liu. (2020) The landscape of BCR‐ABL mutations in patients with Philadelphia chromosome‐positive leukaemias in the era of second‐generation tyrosine kinase inhibitors . Hematological Oncology 38:3, pages 390-398.
Crossref
Irina Cezara Vacarean-Trandafir, Iuliu Cristian Ivanov, Loredana Mihaiela Dragos, Angela Smaranda Dascalescu, Amalia Andrea Titieanu & Dumitru Cojocaru. (2019) ABL1 tyrosine kinase domain mutations in chronic myeloid leukemia treatment resistance. Molecular Biology Reports 46:4, pages 3747-3754.
Crossref
Prashant Ajit Deshpande, Gajanan Bhanudas Padmawar & Venkatesh S Ekbote. (2021) A novel in-frame 231bp deletion mutation in ABL1 kinase activation loop. Indian Journal of Medical and Paediatric Oncology 40:01, pages 141-143.
Crossref
Ilya Mikhailov. (2018) BCR-ABL exon 7 deletion and novel point mutation in patient with chronic myelogenous leukemia and TKI resistance. Clinical Case Reports 6:11, pages 2057-2060.
Crossref
Vera Vyacheslavovna Tikhonova, M.A. Isakov, V.A. Misyurin, Yu.P. Finashutina, L.A. Kesaeva, N.A. Lyzhko, I.N. Soldatova, N.N. Kasatkina, E.N. Misyurina & A.V. Misyurin. (2018) Tyrosine Kinase Inhibitor Resistance in Patients with Chronic Myeloid Leukemia: A 10-Year Study of BCR-ABL Gene Mutation Profile in Russia (2006-2016). Clinical oncohematology 11:3, pages 227-233.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.