Advanced search
Publication Cover
Leukemia & Lymphoma Volume 57, 2016 - Issue 12
Submit an article Journal homepage
436
Views
8
CrossRef citations to date
0
Altmetric
Letter to the Editor

Next-generation sequencing identifies a novel ELAVL1–TYK2 fusion gene in MOLM-16, an AML cell line highly sensitive to the PIM kinase inhibitor AZD1208

Adriana E. TronOncology iMed, AstraZeneca, Waltham, MA, USA; Correspondence[email protected]
,
Erika K. KeetonOncology iMed, AstraZeneca, Waltham, MA, USA; ;N-of-One, Inc, Lexington, MA, USA;
,
Minwei YeOncology iMed, AstraZeneca, Waltham, MA, USA;
,
Matias Casas-SelvesOncology iMed, AstraZeneca, Waltham, MA, USA; ;Drug Discovery Program, Ontario Institute for Cancer Research, Toronto, Canada;
,
Huawei ChenOncology iMed, AstraZeneca, Waltham, MA, USA;
,
Keith S. DillmanOncology iMed, AstraZeneca, Waltham, MA, USA;
,
Rosemary E. GaleDepartment of Haematology, University College London Cancer Institute, London, UK;
,
Chloe StengelDepartment of Haematology, University College London Cancer Institute, London, UK;
,
Michael ZindaOncology iMed, AstraZeneca, Waltham, MA, USA;
,
David C. LinchDepartment of Haematology, University College London Cancer Institute, London, UK;
,
Zhongwu LaiOncology iMed, AstraZeneca, Waltham, MA, USA;
,
Asim KhwajaDepartment of Haematology, University College London Cancer Institute, London, UK;
&
Dennis HuszarOncology iMed, AstraZeneca, Waltham, MA, USA; ;Oncology Drug Discover Unit, Takeda Pharmaceuticals International Co, Cambridge, MA, USA
 show all
Pages 2927-2929 | Received 20 Jan 2016, Accepted 24 Mar 2016, Published online: 17 May 2016

Citations (8)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (1)

Stefan Moritsch, Bernadette Mödl, Irene Scharf, Lukas Janker, Daniela Zwolanek, Gerald Timelthaler, Emilio Casanova, Maria Sibilia, Thomas Mohr, Lukas Kenner, Dietmar Herndler-Brandstetter, Christopher Gerner, Mathias Müller, Birgit Strobl & Robert Eferl. (2022) Tyk2 is a tumor suppressor in colorectal cancer. OncoImmunology 11:1.
Read now

Articles from other publishers (7)

Paniz Tavakoli Shirazi, Laura N. Eadie, Susan L. Heatley, Elyse C. Page, Maxime François, Timothy P. Hughes, David Yeung & Deborah L. White. (2022) Exploring the oncogenic and therapeutic target potential of the MYB-TYK2 fusion gene in B-cell acute lymphoblastic leukemia. Cancer Gene Therapy 29:8-9, pages 1140-1152.
Crossref
Juuli Raivola, Teemu Haikarainen, Bobin George Abraham & Olli Silvennoinen. (2021) Janus Kinases in Leukemia. Cancers 13:4, pages 800.
Crossref
Katharina Wöss, Natalija Simonović, Birgit Strobl, Sabine Macho-Maschler & Mathias Müller. (2019) TYK2: An Upstream Kinase of STATs in Cancer. Cancers 11:11, pages 1728.
Crossref
Natalija Simonović, Agnieszka Witalisz-Siepracka, Katrin Meissl, Caroline Lassnig, Ursula Reichart, Thomas Kolbe, Matthias Farlik, Christoph Bock, Veronika Sexl, Mathias Müller & Birgit Strobl. (2019) NK Cells Require Cell-Extrinsic and -Intrinsic TYK2 for Full Functionality in Tumor Surveillance and Antibacterial Immunity. The Journal of Immunology 202:6, pages 1724-1734.
Crossref
Nicole Prutsch, Elisabeth Gurnhofer, Tobias Suske, Huan Chang Liang, Michaela Schlederer, Simone Roos, Lawren C. Wu, Ingrid Simonitsch-Klupp, Andrea Alvarez-Hernandez, Christoph Kornauth, Dario A. Leone, Jasmin Svinka, Robert Eferl, Tanja Limberger, Astrid Aufinger, Nitesh Shirsath, Peter Wolf, Thomas Hielscher, Christina Sternberg, Fritz Aberger, Johannes Schmoellerl, Dagmar Stoiber, Birgit Strobl, Ulrich Jäger, Philipp B. Staber, Florian Grebien, Richard Moriggl, Mathias Müller, Giorgio G. Inghirami, Takaomi Sanda, A. Thomas Look, Suzanne D. Turner, Lukas Kenner & Olaf Merkel. (2018) Dependency on the TYK2/STAT1/MCL1 axis in anaplastic large cell lymphoma. Leukemia 33:3, pages 696-709.
Crossref
Keigo Okada, Ayako Nogami, Shinya Ishida, Hiroki Akiyama, Cheng Chen, Yoshihiro Umezawa & Osamu Miura. (2017) FLT3-ITD induces expression of Pim kinases through STAT5 to confer resistance to the PI3K/Akt pathway inhibitors on leukemic cells by enhancing the mTORC1/Mcl-1 pathway. Oncotarget 9:10, pages 8870-8886.
Crossref
Shivani Kapoor, Karthika Natarajan, Patrick R. Baldwin, Kshama A. Doshi, Rena G. Lapidus, Trevor J. Mathias, Mario Scarpa, Rossana Trotta, Eduardo Davila, Manfred Kraus, Dennis Huszar, Adriana E. Tron, Danilo Perrotti & Maria R. Baer. (2018) Concurrent Inhibition of Pim and FLT3 Kinases Enhances Apoptosis of FLT3-ITD Acute Myeloid Leukemia Cells through Increased Mcl-1 Proteasomal Degradation. Clinical Cancer Research 24:1, pages 234-247.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.