Advanced search
Publication Cover
Leukemia & Lymphoma Volume 11, 1993 - Issue 5-6
Submit an article Journal homepage
28
Views
28
CrossRef citations to date
0
Altmetric
Original Article

Phase I Trial of the Diphtheria Toxin/Interleukin-2 Fusion Protein DAB486IL-2: Efficacy in Mycosis Fungoides and Other Non-Hodgkin's Lymphomas

Timothy M. Kuzel Department of Medicine, Division of Hematology/Oncology Robert H. Lurie Cancer Center and the VA Lakeside Medical Center, Chicago, Illinois
,
Steven T. Rosen Department of Medicine, Division of Hematology/Oncology Robert H. Lurie Cancer Center and the VA Lakeside Medical Center, Chicago, Illinois
,
Leo I. Gordon Department of Medicine, Division of Hematology/Oncology Robert H. Lurie Cancer Center and the VA Lakeside Medical Center, Chicago, Illinois
,
Jane Winter Department of Medicine, Division of Hematology/Oncology Robert H. Lurie Cancer Center and the VA Lakeside Medical Center, Chicago, Illinois
,
Ellen Samuelson Department of Medicine, Division of Hematology/Oncology Robert H. Lurie Cancer Center and the VA Lakeside Medical Center, Chicago, Illinois
,
Karen Kaul Department of Pathology, Robert H. Lurie Cancer Center and the VA Lakeside Medical Center, Chicago, Illinois
,
Henry H. Roenigk Department of Dermatology, Northwestern University Medical School, Robert H. Lurie Cancer Center and the VA Lakeside Medical Center, Chicago, Illinois
,
Pamela Nylen Seragen, Inc., Hopkinton, Massachusetts, USA
&
Thasia Woodworth Seragen, Inc., Hopkinton, Massachusetts, USA
 show all
Pages 369-377 | Received 28 Feb 1993, Published online: 01 Jul 2009

Citations (28)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (6)

Bahman Akbari, Safar Farajnia, Shiva Ahdi Khosroshahi, Fatemeh Safari, Mohammadreza Yousefi, Hassan Dariushnejad & Leila Rahbarnia. (2017) Immunotoxins in cancer therapy: Review and update. International Reviews of Immunology 36:4, pages 207-219.
Read now
David Kaminetzky & Kenneth B Hymes. (2008) Denileukin diftitox for the treatment of cutaneous T-cell lymphoma. Biologics: Targets and Therapy 2:4, pages 717-724.
Read now
Francesco Turturro. (2007) Denileukin diftitox: a biotherapeutic paradigm shift in the treatment of lymphoid-derived disorders. Expert Review of Anticancer Therapy 7:1, pages 11-17.
Read now
Bryan Y. Wong, Stephanie A. Gregory & Nam H. Dang. (2007) Denileukin Diftitox as Novel Targeted Therapy for Lymphoid Malignancies. Cancer Investigation 25:6, pages 495-501.
Read now
John W Eklund & Timothy M Kuzel. (2005) Denileukin diftitox: a concise clinical review. Expert Review of Anticancer Therapy 5:1, pages 33-38.
Read now
Robert J Kreitman. (1998) Recombinant toxins in haematologic malignancies and solid tumours. Expert Opinion on Investigational Drugs 7:9, pages 1405-1427.
Read now

Articles from other publishers (22)

Fatemeh Shafiee, Marc G. Aucoin & Ali Jahanian-Najafabadi. (2019) Targeted Diphtheria Toxin-Based Therapy: A Review Article. Frontiers in Microbiology 10.
Crossref
Katja Spiess, Mette Høy Jakobsen, Thomas N Kledal & Mette M Rosenkilde. (2016) The future of antiviral immunotoxins. Journal of Leukocyte Biology 99:6, pages 911-925.
Crossref
Larisa J. Geskin. (2015) Monoclonal Antibodies. Dermatologic Clinics 33:4, pages 777-786.
Crossref
Nurit Becker & Itai Benhar. (2012) Antibody-Based Immunotoxins for the Treatment of Cancer. Antibodies 1:1, pages 39-69.
Crossref
Assaf Shapira & Itai Benhar. (2010) Toxin-Based Therapeutic Approaches. Toxins 2:11, pages 2519-2583.
Crossref
Z Wang, Z Tang, Y Zheng, D Yu, M Spear, S R Iyer, B Bishop & Y Wu. (2010) Development of a nonintegrating Rev-dependent lentiviral vector carrying diphtheria toxin A chain and human TRAF6 to target HIV reservoirs. Gene Therapy 17:9, pages 1063-1076.
Crossref
Lin‐Chi Chen & Nam H. Dang. 2010. Emerging Cancer Therapy. Emerging Cancer Therapy 289 307 .
Apostolia-Maria Tsimberidou, Francis J Giles, Madeleine Duvic & Razelle Kurzrock. (2004) Pilot study of etanercept in patients with relapsed cutaneous T-cell lymphomas. Journal of the American Academy of Dermatology 51:2, pages 200-204.
Crossref
Robert V. House. 2003. Biotechnology and Safety Assessment. Biotechnology and Safety Assessment 191 231 .
Narin Apisarnthanarax, Rakshandra Talpur & Madeleine Duvic. (2002) Treatment of Cutaneous T Cell Lymphoma. American Journal of Clinical Dermatology 3:3, pages 193-215.
Crossref
Narin Apisarnthanarax & Madeleine Duvic. (2001) CUTANEOUS T-CELL LYMPHOMA. Dermatologic Clinics 19:4, pages 737-748.
Crossref
FRANCINE M. FOSS. (2006) Interleukin-2 Fusion Toxin: Targeted Therapy for Cutaneous T Cell Lymphoma. Annals of the New York Academy of Sciences 941:1, pages 166-176.
Crossref
Timothy M. Kuzel. (2000) DAB389IL-2 (Denileukin Diftitox, ONTAK): Review of Clinical Trials to Date. Clinical Lymphoma 1, pages S33-S36.
Crossref
Francine M. Foss. (2000) DAB389IL-2 (Denileukin Diftitox, ONTAK): A New Fusion Protein Technology. Clinical Lymphoma 1, pages S27-S31.
Crossref
Francine M. Foss. (2000) DAB389IL-2 (ONTAK): A Novel Fusion Toxin Therapy for Lymphoma. Clinical Lymphoma 1:2, pages 110-116.
Crossref
Robert J. KreitmanWyndham H. WilsonJeffrey D. WhiteMaryalice Stetler-StevensonElaine S. JaffeSteven GiardinaThomas A. WaldmannIra Pastan. (2000) Phase I Trial of Recombinant Immunotoxin Anti-Tac(Fv)-PE38 (LMB-2) in Patients With Hematologic Malignancies. Journal of Clinical Oncology 18:8, pages 1622-1636.
Crossref
RK Burt, J Guitart, A Traynor, C Link, S Rosen, T Pandolfino & TM Kuzel. (2000) Allogeneic hematopoietic stem cell transplantation for advanced mycosis fungoides: evidence of a graft-versus-tumor effect. Bone Marrow Transplantation 25:1, pages 111-113.
Crossref
Christina Rogalski, Reinhard Dummer & Günter Burg. (2006) Immunomodulators in the treatment of cutaneous lymphoma. Journal of the European Academy of Dermatology and Venereology 13:2, pages 83-90.
Crossref
Francine M. Foss & Timothy M. Kuzel. 1999. Diagnostic and Therapeutic Advances in Hematologic Malignancies. Diagnostic and Therapeutic Advances in Hematologic Malignancies 227 240 .
Robert J Kreitman & Ira Pastan. (1998) Immunotoxins for targeted cancer therapy. Advanced Drug Delivery Reviews 31:1-2, pages 53-88.
Crossref
G. Burg, R. Dummer & F. Nestle. 1997. Strategies for Immunointerventions in Dermatology. Strategies for Immunointerventions in Dermatology 321 335 .
H.M. Lazarus & J.M. Rowe. (1995) New and experimental therapies for treating graft-versus-host disease. Blood Reviews 9:2, pages 117-133.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.