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Original Article

Phase II Clinical Trial of Fludarabine in Chronic Lymphocytic Leukemia on a Weekly Low-Dose Schedule

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Pages 187-193 | Received 24 Oct 1992, Published online: 01 Jul 2009

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Nathan R. Wall, Frances W.J. Beck, Ayad M. Al-Katib & Ramzi M. Mohammad. (2001) Treatment-induced Expression of Anti-apoptotic Proteins in WSU-CLL, a Human Chronic Lymphocytic Leukemia Cell Line. Journal of Drug Targeting 9:5, pages 329-339.
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M. J. Keating, T. L. Smith, S. Lerner, S. O'brien, L. E. Robertson, H. Kantarjian & E. J. Freireich. (2000) Prediction of Prognosis Following Fludarabine Used as Secondary Therapy for Chronic Lymphocytic Leukemia. Leukemia & Lymphoma 37:1-2, pages 71-85.
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John F. Seymour, L. E. Robertson, Susan O'brien, Susan Lerner & Michael J. Keating. (1995) Survival of Young Patients with Chronic Lymphocytic Leukemia Failing Fludarabine Therapy: A Basis for the Use of Myeloablative Therapies. Leukemia & Lymphoma 18:5-6, pages 493-496.
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Francesco Di Raimondo, GIUSEPPE Albero Palumbo, Maria Anna Romeo, Emma Cacciola, Giuseppe Milone, Stefana Impera, Rosario Giustoliis & ELI0 Cacciola. (1995) In Vitro Sensitivity of B-CLL Cells to Fludarabine and Interferons. Leukemia & Lymphoma 17:5-6, pages 449-453.
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Michael J. Keating, Susan O'brien, Lester E. Robertson, Hagop Kantarjian, Meletios Dimopoulos, Peter McLaughlin, Fernando Cabanillas, Vincent Gregoire, Li Ying-Yang, Varsha Gandhi, Elihu Estey & William Plunkett. (1994) The Expanding Role of Fludarabine in Hematologic Malignancies. Leukemia & Lymphoma 14:sup2, pages 11-16.
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M. J. Keating, S. O'brien, L. Robertson, Y. Huh, H. Kantarjian & W. Plunkett. (1993) Chronic Lymphocytic Leukemia—Correlation of Response and Survival. Leukemia & Lymphoma 11:sup2, pages 167-175.
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V. Gandhi. (1993) Fludarabine for Treatment of Adult Acute Myelogenous Leukemia. Leukemia & Lymphoma 11:sup2, pages 7-13.
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Articles from other publishers (25)

Karen W. L. Yee & Susan M. O'Brien. 2011. Management of Hematologic Malignancies. Management of Hematologic Malignancies 81 102 .
Lev ShvidelMirel CohnErica Sigler. (2009) Pharmacotherapy Update: Fludarabine in the Treatment of Non-Hodgkin's Lymphoma. Clinical Medicine. Therapeutics 1, pages CMT.S2553.
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Karen Yee, Michael Keating & Susan O’Brien. 2008. Chronic Lymphocytic Leukemia. Chronic Lymphocytic Leukemia 141 164 .
Karen W.L. Yee & Susan M. O'Brien. (2006) Chronic Lymphocytic Leukemia: Diagnosis and Treatment. Mayo Clinic Proceedings 81:8, pages 1105-1129.
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William G Wierda, Michael J Keating & Susan O??Brien. (2004) Refractory Chronic Lymphocytic Leukemia. American Journal of Cancer 3:3, pages 163-178.
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Alessandra Ferrajoli, Michael J. Keating & Susan M. O’Brien. 2004. Chronic Lymphocytic Leukemia. Chronic Lymphocytic Leukemia 241 254 .
Gerassimos A. Pangalis, Theodoros P. Vassilakopoulos, Maria N. Dimopoulou, Marina P. Siakantaris, Flora N. Kontopidou & Maria K. Angelopoulou. (2002) B‐chronic lymphocytic leukemia: practical aspects. Hematological Oncology 20:3, pages 103-146.
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Varsha Gandhi & William Plunkett. (2002) Cellular and Clinical Pharmacology of Fludarabine. Clinical Pharmacokinetics 41:2, pages 93-103.
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M. A. BoogaertsA. Van HoofD. CatovskyM. KovacsM. MontilloP. L. ZinzaniJ. L. BinetW. FeremansR. MarcusF. BoschG. VerhoefM. Klein. (2001) Activity of Oral Fludarabine Phosphate in Previously Treated Chronic Lymphocytic Leukemia. Journal of Clinical Oncology 19:22, pages 4252-4258.
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Vicki A. MorrisonKanti R. RaiBercedis L. PetersonJonathan E. KolitzLaurence EliasFrederick R. AppelbaumJohn D. HinesLois ShepherdRobert E. MartellRichard A. LarsonCharles A. Schiffer. (2001) Impact of Therapy With Chlorambucil, Fludarabine, or Fludarabine Plus Chlorambucil on Infections in Patients With Chronic Lymphocytic Leukemia: Intergroup Study Cancer and Leukemia Group B 9011. Journal of Clinical Oncology 19:16, pages 3611-3621.
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F. Di Raimondo, R. Giustolisi, S. Lerner, E. Cacciola, S. O’Brien, H. Kantarjian & M.J. Keating. (2001) Retrospective study of the prognostic role of serum thymidine kinase level in CLL patients with active disease treated with fludarabine. Annals of Oncology 12:5, pages 621-625.
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Stephen A. Johnson. (2000) Clinical Pharmacokinetics of Nucleoside Analogues. Clinical Pharmacokinetics 39:1, pages 5-26.
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Michael J. Keating & Susan O’Brien. (2001) Conventional Management of Chronic Lymphocytic Leukemia. Reviews in Clinical and Experimental Hematology 4:2, pages 118-133.
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Nelson Kalil & Bruce D. Cheson. (2000) Management of Chronic Lymphocytic Leukaemia. Drugs & Aging 16:1, pages 9-27.
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M. Freund & P. Heußner. 1998. Therapiekonzepte Onkologie. Therapiekonzepte Onkologie 257 332 .
M. J. Keating. 1997. Acute Leukemias VI. Acute Leukemias VI 380 387 .
Alessandra Fraternale, Luigia Rossi & Mauro Magnani. (1996) Encapsulation, metabolism and release of 2-fluoro-ara-AMP from human erythrocytes. Biochimica et Biophysica Acta (BBA) - General Subjects 1291:2, pages 149-154.
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Jill M. Kolesar, Ashley K. Morris & John G. Kuhn. (2016) Review : Purine nucleoside analogues: Fludarabine, pentostatin, and cladribine. Journal of Oncology Pharmacy Practice 2:3, pages 160-181.
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Panos Fidias, Bruce A. Chabner & Michael L. Grossbard. (1996) Purine Analogs for the Treatment of Low-Grade Lymphoproliferative Disorders. The Oncologist 1:3, pages 125-139.
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S. O'Brien, H. Kantarjian & M.J. Keating. (1996) Purine analogs in chronic lymphocytic leukemia and Waldenström's macroglobulinemia. Annals of Oncology 7, pages S27-S33.
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Michael J. Keating. 1996. Acute Leukemias V. Acute Leukemias V 572 577 .
D. Catovsky & R.L.W. Murphy. (1995) Key issues in the treatment of chronic lymphocytic leukaemia (CLL). European Journal of Cancer 31:13-14, pages 2146-2154.
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M. Freund & P. Heußner. 1995. Therapiekonzepte Onkologie. Therapiekonzepte Onkologie 189 268 .
Gerassimos A. Pangalis, Maria K. Angelopoulou, Christos Poziopoulos, Aaron Polliack & Shamuel Gillis. 1995. Malignant Lymphomas: Biology and Treatment. Malignant Lymphomas: Biology and Treatment 151 161 .
M.J. Keating, P. McLaughlin, W. Plunkett, L.E. Robertson, S. O'Brien, V. Gandhi, V. Gregoire, L. Yang & F. Cabanillas. (1994) Original article: Fludarabine – present status and future developments in chronic lymphocytic leukemia and lymphoma. Annals of Oncology 5, pages S79-S83.
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