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Leukemia & Lymphoma Volume 20, 1995 - Issue 1-2
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Original Article

BCL6 Gene Rearrangement and Other Cytogenetic Abnormalities in Diffuse Large Cell Lymphoma

Kenneth Offit Department of Human Genetics, Memorial Sloan-Kettering Cancer Center, New York, NY; Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY
,
Diane C. Louie Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, NY
,
Nasser Z. Parsa Departments of the Cell Biology and Genetics Program, Memorial Sloan-Kettering Cancer Center, New York, NY
,
Pampa Roy Departments of the Cell Biology and Genetics Program, Memorial Sloan-Kettering Cancer Center, New York, NY
,
Denis Leung Department of Epidemiology and Biostatistics, Memorial Sloan-Kettering Cancer Center, New York, NY
,
Francesco Lo Coco Sezione di Ematologia, Dipartimento di Biopatologia Umana, Universita “La Sapienza,”, Rome, Italy
,
Andrew Zelenetz Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY
,
Riccardo Dalla-Favera Department of Pathology, College of Physicians and Surgeons, Columbia University, New York, NY, USA
&
R. S. K. Chaganti Department of Human Genetics, Memorial Sloan-Kettering Cancer Center, New York, NY; Departments of the Cell Biology and Genetics Program, Memorial Sloan-Kettering Cancer Center, New York, NY
 show all
Pages 85-89 | Received 20 Jan 1995, Published online: 01 Jul 2009

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B. Hilda Ye. (2000) BCL-6 in the Pathogenesis of Non-Hodgkin's Lymphoma. Cancer Investigation 18:4, pages 356-365.
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Louis M. Staudt, Alexander L. Dent, A. L. Shaffer & Xin Yu. (1999) Regulation of Lymphocyte Cell Fate Decisions and Lymphomagenesis by BCL-6. International Reviews of Immunology 18:4, pages 381-403.
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Hitoshi Ohno & Shirou Fukuhara. (1997) Significance of Rearrangement of the BCL6 Gene in B-Cell Lymphoid Neoplasms. Leukemia & Lymphoma 27:1-2, pages 53-63.
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Ginette Y. Michaud, Randy D. Gascoyne, B. Kelly McNeil, Michelle E. Anderson & Douglas E. Horsman. (1997) Bcl-6 and Lymphoproliferative Disorders. Leukemia & Lymphoma 26:5-6, pages 515-525.
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Articles from other publishers (22)

Claudio Ortolani. 2021. Flow Cytometry of Hematological Malignancies. Flow Cytometry of Hematological Malignancies 301 427 .
Wenjun Wu, Zhihui Xiao, Deon Buritis & Vladimir Poltoratsky. 2020. Immune Mediators in Cancer. Immune Mediators in Cancer 167 179 .
Alexei G. BakhirevMohammad A. VasefQian-Yun ZhangKaaren K. ReichardDavid R. Czuchlewski. (2014) Fluorescence Immunophenotyping and Interphase Cytogenetics (FICTION) Detects BCL6 Abnormalities, Including Gene Amplification, in Most Cases of Nodular Lymphocyte-Predominant Hodgkin Lymphoma. Archives of Pathology & Laboratory Medicine 138:4, pages 538-542.
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Claudio Ortolani. 2011. Flow Cytometry of Hematological Malignancies. Flow Cytometry of Hematological Malignancies 160 300 .
Ana Mozos, Hongtao Ye, Wen-Yu Chuang, Jan-Show Chu, Wan-Ting Huang, Han-Ku Chen, Yung-Hsiang Hsu, Chris M Bacon, Ming-Qing Du, Elias Campo & Shih-Sung Chuang. (2009) Most primary adrenal lymphomas are diffuse large B-cell lymphomas with non-germinal center B-cell phenotype, BCL6 gene rearrangement and poor prognosis. Modern Pathology 22:9, pages 1210-1217.
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Maria Grazia Tibiletti, Vittoria Martin, Barbara Bernasconi, Barbara Del Curto, Lorenza Pecciarini, Silvia Uccella, Giancarlo Pruneri, Maurillio Ponzoni, Luca Mazzucchelli, Giovanni Martinelli, Andrés J. Ferreri, Graziella Pinotti, Andrea Assanelli, Marta Scandurra, Claudio Doglioni, Emanuele Zucca, Carlo Capella & Francesco Bertoni. (2009) BCL2, BCL6, MYC, MALT 1, and BCL10 rearrangements in nodal diffuse large B-cell lymphomas: a multicenter evaluation of a new set of fluorescent in situ hybridization probes and correlation with clinical outcome. Human Pathology 40:5, pages 645-652.
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Jahan-Yar Parsa, Wajiha Basit, Clifford L. Wang, Jennifer L. Gommerman, James R. Carlyle & Alberto Martin. (2007) AID mutates a non-immunoglobulin transgene independent of chromosomal position. Molecular Immunology 44:4, pages 567-575.
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Doug Horsman. 2006. The Lymphomas. The Lymphomas 39 62 .
Ryan T Phan, Masumichi Saito, Katia Basso, Huifeng Niu & Riccardo Dalla-Favera. (2005) BCL6 interacts with the transcription factor Miz-1 to suppress the cyclin-dependent kinase inhibitor p21 and cell cycle arrest in germinal center B cells. Nature Immunology 6:10, pages 1054-1060.
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Cyrus V Hedvat, Julie Teruya-Feldstein, Pere Puig, Paola Capodieci, Maria Dudas, Natalie Pica, Jing Qin, Carlos Cordon-Cardo & Charles J Di Como. (2005) Expression of p63 in Diffuse Large B-Cell Lymphoma. Applied Immunohistochemistry & Molecular Morphology 13:3, pages 237-242.
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Ryan T. Phan & Riccardo Dalla-Favera. (2004) The BCL6 proto-oncogene suppresses p53 expression in germinal-centre B cells. Nature 432:7017, pages 635-639.
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M Bai, N J Agnantis, A Skyrlas, E Tsanou, S Kamina, V Galani & P Kanavaros. (2003) Increased Expression of the bcl6 and CD10 Proteins Is Associated with Increased Apoptosis and Proliferation in Diffuse Large B-Cell Lymphomas. Modern Pathology 16:5, pages 471-480.
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F Jardin, P Gaulard, G Buchonnet, N Contentin, S Leprêtre, P Lenain, A Stamatoullas, JM Picquenot, C Duval, F Parmentier, H Tilly & C Bastard. (2002) Follicular lymphoma without t(14;18) and with BCL-6 rearrangement: a lymphoma subtype with distinct pathological, molecular and clinical characteristics. Leukemia 16:11, pages 2309-2317.
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F Jardin, G Buchonnet, F Parmentier, N Contentin, S Leprêtre, P Lenain, JM Picquenot, S Laberge, P Bertrand, A Stamatoullas, J d'Anjou, H Tilly & C Bastard. (2002) Follicle center lymphoma is associated with significantly elevated levels of BCL-6 expression among lymphoma subtypes, independent of chromosome 3q27 rearrangements. Leukemia 16:11, pages 2318-2325.
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Alexander L. Dent, Farha H Vasanwala & Lisa M Toney. (2002) Regulation of gene expression by the proto-oncogene BCL-6. Critical Reviews in Oncology/Hematology 41:1, pages 1-9.
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G. B. Mann & K. C. Conlon. 2002. Staging Laparoscopy. Staging Laparoscopy 169 178 .
Brian F Skinnider, Douglas E Horsman, Beverley Dupuis & Randy D Gascoyne. (1999) Bcl-6 and Bcl-2 protein expression in diffuse large B-cell lymphoma and follicular lymphoma: Correlation with 3q27 and 18q21 chromosomal abnormalities. Human Pathology 30:7, pages 803-808.
Crossref
M.H.H. KramerJ. HermansE. WijburgK. PhilippoE. GeelenJ.H.J.M. van KriekenD. de JongE. MaartenseE. SchuuringP.M. Kluin. (1998) Clinical Relevance of BCL2, BCL6, and MYC Rearrangements in Diffuse Large B-Cell Lymphoma. Blood 92:9, pages 3152-3162.
Crossref
M.H.H. KramerJ. HermansE. WijburgK. PhilippoE. GeelenJ.H.J.M. van KriekenD. de JongE. MaartenseE. SchuuringP.M. Kluin. (1998) Clinical Relevance of BCL2, BCL6, and MYC Rearrangements in Diffuse Large B-Cell Lymphoma. Blood 92:9, pages 3152-3162.
Crossref
Mamta V. Manglani, Curt G. DeGroff, Peter P. Dukes & Lawrence J. Ettinger. (1998) Congenital Erythrocytosis With Elevated Erythropoietin Level. Journal of Pediatric Hematology/Oncology 20:6, pages 560-562.
Crossref
Norihiko Kawamata, Yuichi Nakamura, Toru Miki, Eriko Sato, Yasushi Isobe, Sinpei Furusawa, Shinsaku Hirosawa & Kazuo Oshimi. (1998) Detection of chimaeric transcripts of the immunoglobulin heavy chain and BCL6 genes by reverse-transcriptase polymerase chain reaction in B-cell non-Hodgkin's lymphomas. British Journal of Haematology 100:3, pages 484-489.
Crossref
Soumaya El Rouby, P.H. Rao & Elizabeth W. Newcomb. (1997) Assignment of the Human B-Cell-Derived (BCD1) Proto-oncogene to 10p14–p15. Genomics 43:3, pages 395-397.
Crossref

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