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Leukemia & Lymphoma Volume 18, 1995 - Issue 3-4
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Original Article

BCR-ABL: An Anti-Apoptosis Gene in Chronic Myelogenous Leukemia

Thomas G. Cotter Department of Biochemistry, University College, Cork, Ireland
Pages 231-236 | Received 27 Aug 1994, Published online: 01 Jul 2009

Citations (28)

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Carmine Selleri & Jaroslaw P. Maciejewski. (2000) The Role of FAS-Mediated Apoptosis in Chronic Myelogenous Leukemia. Leukemia & Lymphoma 37:3-4, pages 283-297.
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Articles from other publishers (27)

Qiaoli Zheng, Jiang Cao, Nada Hamad, Hyeoung-Joon Kim, Joon Ho Moon, Sang Kyun Sohn, Chul Won Jung, Jeffrey H. Lipton & Dennis Dong Hwan Kim. (2016) Single nucleotide polymorphisms in apoptosis pathway are associated with response to imatinib therapy in chronic myeloid leukemia. Journal of Translational Medicine 14:1.
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Sitapriya Moorthi & Chiara Luberto. 2015. Bioactive Sphingolipids in Cancer Biology and Therapy. Bioactive Sphingolipids in Cancer Biology and Therapy 53 79 .
Timothy S. PardeeEvan GomesJamie Jennings-Gee, David Caudell & William H. Gmeiner. (2012) Unique dual targeting of thymidylate synthase and topoisomerase1 by FdUMP[10] results in high efficacy against AML and low toxicity. Blood 119:15, pages 3561-3570.
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Edward Kavalerchik, Daniel Goff & Catriona H.M. Jamieson. (2008) Chronic Myeloid Leukemia Stem Cells. Journal of Clinical Oncology 26:17, pages 2911-2915.
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Lisa M. Greene, Liam Kelly, Valeria Onnis, Giuseppe Campiani, Mark Lawler, D. Clive Williams & Daniela M. Zisterer. (2007) STI-571 (Imatinib Mesylate) Enhances the Apoptotic Efficacy of Pyrrolo-1,5-Benzoxazepine-6, a Novel Microtubule-Targeting Agent, in Both STI-571-Sensitive and -Resistant Bcr-Abl-Positive Human Chronic Myeloid Leukemia Cells. Journal of Pharmacology and Experimental Therapeutics 321:1, pages 288-297.
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D.V. Raghuvar Gopal, Archana A. Narkar, Y. Badrinath, K.P. Mishra & D.S. Joshi. (2005) Betulinic acid induces apoptosis in human chronic myelogenous leukemia (CML) cell line K-562 without altering the levels of Bcr-Abl. Toxicology Letters 155:3, pages 343-351.
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Ireneusz Majsterek, Artur Slupianek & Janusz Blasiak. (2003) TEL-fusion oncogenic tyrosine kinases determine leukemic cells response to idarubicin. Anti-Cancer Drugs 14:8, pages 625-631.
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Qi Feng, Kai Sun, Yong-tong Zhao, Tao Zhang, Zhen-chuan Shang, Sha Wang, Wei Wang, Ning Zhao, Zhen Yan, Wei Han, Ying-qi Zhang & Bing-zhong Sun. (2003) Gene therapy using retro viral vector of bcr-abl specific multi-unit ribozymes could inhibit CML cell growth and induce apoptosis. Chinese Journal of Cancer Research 15:3, pages 167-171.
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M. DrostenT. StieweB.M. Pützer. (2003) Antitumor Capacity of a Dominant-Negative RET Proto-Oncogene Mutant in a Medullary Thyroid Carcinoma Model . Human Gene Therapy 14:10, pages 971-982.
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Stephanie Salesse & Catherine M Verfaillie. (2002) BCR/ABL: from molecular mechanisms of leukemia induction to treatment of chronic myelogenous leukemia. Oncogene 21:56, pages 8547-8559.
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Colm Power, Noel Fanning & H. Paul Redmond. (2002) Cellular Apoptosis and Organ Injury in Sepsis: A Review. Shock 18:3, pages 197-211.
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AS Shet, BN Jahagirdar & CM Verfaillie. (2002) Chronic myelogenous leukemia: mechanisms underlying disease progression. Leukemia 16:8, pages 1402-1411.
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Anjali S. Advani & Ann Marie Pendergast. (2002) Bcr–Abl variants: biological and clinical aspects. Leukemia Research 26:8, pages 713-720.
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Farhad Ravandi, Hagop M. Kantarjian, Moshe Talpaz, Susan O'Brien, Stefan Faderl, Francis J. Giles, Debbie Thomas, Jorge Cortes, Michael Andreeff, Zeev Estrov, Mary-Beth Rios & Maher Albitar. (2001) Expression of apoptosis proteins in chronic myelogenous leukemia. Cancer 91:11, pages 1964-1972.
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Balkrishna N Jahagirdar, Jeffrey S Miller, Arun Shet & Catherine M Verfaillie. (2001) Novel therapies for chronic myelogenous leukemia. Experimental Hematology 29:5, pages 543-556.
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Patricia A. Zipfel, Matthew Grove, Kevin Blackburn, Manabu Fujimoto, Thomas F. Tedder & Ann Marie Pendergast. (2000) The c-Abl Tyrosine Kinase Is Regulated Downstream of the B Cell Antigen Receptor and Interacts with CD19. The Journal of Immunology 165:12, pages 6872-6879.
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H. Sedlacek. (2000) Kinase Inhibitors in Cancer Therapy. Drugs 59:3, pages 435-476.
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Catherine M. Verfaillie, R.Scott McIvor & Robert C.H. Zhao. (1999) Gene therapy for chronic myelogenous leukemia. Molecular Medicine Today 5:8, pages 359-366.
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Catherine M. Verfaillie. (1999) Chronic Myelogenous Leukemia: From Pathogenesis to Therapy. Journal of Hematotherapy 8:1, pages 3-13.
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Carmine SelleriJaroslaw P. MaciejewskiFabrizio PaneLuigia LucianoAnna Maria RaiolaIlaria MostardaFrancesco SalvatoreBruno Rotoli. (1998) Fas-Mediated Modulation of Bcr/Abl in Chronic Myelogenous Leukemia Results in Differential Effects on Apoptosis. Blood 92:3, pages 981-989.
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Catherine M. Verfaillie. (1998) BIOLOGY OF CHRONIC MYELOGENOUS LEUKEMIA. Hematology/Oncology Clinics of North America 12:1, pages 1-29.
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Catherine M. Verfaillie. (1997) STEM CELLS IN CHRONIC MYELOGENOUS LEUKEMIA. Hematology/Oncology Clinics of North America 11:6, pages 1079-1114.
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A. J. O'Neill, T. G. Cotter, J. M. Russell & E. F. Gaffney. (1997) Abl expression in human fetal and adult tissues, tumours and tumour microvessels. The Journal of Pathology 183:3, pages 325-329.
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Ana Maria Tari, Ralph Arlinghaus & Gabriel Lopez-Berestein. (1997) Inhibition of Grb2 and Crkl Proteins Results in Growth Inhibition of Philadelphia Chromosome Positive Leukemic Cells. Biochemical and Biophysical Research Communications 235:2, pages 383-388.
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Carmine SelleriTadatsugu SatoLuigi Del VecchioLuigia LucianoA. John BarrettBruno RotoliNeal S. YoungJaroslaw P. Maciejewski. (1997) Involvement of Fas-Mediated Apoptosis in the Inhibitory Effects of Interferon-α in Chronic Myelogenous Leukemia. Blood 89:3, pages 957-964.
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George Klein. 1997. 1 23 .
JUERGEN THIELE, THOMAS KARL ZIRBES, HANS MICHAEL KVASNICKA, JOHANN LORENZEN, NORBERT NIEDERLE, LUTZ-DIETRICH LEDER & ROBERT FISCHER. (1996) Effect of Interferon Therapy on Bone Marrow Morphology in Chronic Myeloid Leukemia: A Cytochemical and Immunohistochemical Study of Trephine Biopsies. Journal of Interferon & Cytokine Research 16:3, pages 217-224.
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