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Leukemia & Lymphoma Volume 23, 1996 - Issue 1-2

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Original Article

The Involvement of the Candidate Proto-Oncogene NFKB2/lyt-10 in Lymphoid Malignancies

Antonino Neri Laboratorio di Ematologia Sperimentale e Genetica Molecolare, Servizio di Ematologia, Istituto di Scienze Mediche, Università di Milano, Ospedale Maggiore IRCCS, Milan, Italy

Nicola S. Fracchiolla Laboratorio di Ematologia Sperimentale e Genetica Molecolare, Servizio di Ematologia, Istituto di Scienze Mediche, Università di Milano, Ospedale Maggiore IRCCS, Milan, Italy

Anna Migliazza Laboratorio di Ematologia Sperimentale e Genetica Molecolare, Servizio di Ematologia, Istituto di Scienze Mediche, Università di Milano, Ospedale Maggiore IRCCS, Milan, Italy

Dino Trecca Laboratorio di Ematologia Sperimentale e Genetica Molecolare, Servizio di Ematologia, Istituto di Scienze Mediche, Università di Milano, Ospedale Maggiore IRCCS, Milan, Italy

Luigia Lombardi Laboratorio di Ematologia Sperimentale e Genetica Molecolare, Servizio di Ematologia, Istituto di Scienze Mediche, Università di Milano, Ospedale Maggiore IRCCS, Milan, Italy

Pages 43-48 | Received 12 Dec 1995, Published online: 01 Jul 2009

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https://doi.org/10.3109/10428199609054800

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Maria Letizia Giardino Torchia, Dietrich B. Conze, Dragana Jankovic & Jonathan D. Ashwell. (2013) Balance between NF-κB p100 and p52 Regulates T Cell Costimulation Dependence. The Journal of Immunology 190:2, pages 549-555.
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Véronique Baud & Emilie Jacque. (2008) Voie alternative d’activation de NF-κB et cancer. médecine/sciences 24:12, pages 1083-1088.
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Graham Packham. (2008) The role of NF-κB in lymphoid malignancies. British Journal of Haematology 143:1, pages 3-15.
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Masato Isogawa, Masaya Higuchi, Masahiko Takahashi, Masayasu Oie, Naoki Mori, Yuetsu Tanaka, Yutaka Aoyagi & Masahiro Fujii. (2008) Rearranged NF-κB2 gene in an adult T-cell leukemia cell line. Cancer Science 99:4, pages 792-798.
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María Cortés Sempere, Vanesa Rodríguez Fanjul, Isabel Sánchez Pérez & Rosario Perona. (2008) The role of the NFκB signalling pathway in cancer. Clinical and Translational Oncology 10:3, pages 143-147.
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Feng Guo, Debra Weih, Elke Meier & Falk Weih. (2007) Constitutive alternative NF-κB signaling promotes marginal zone B-cell development but disrupts the marginal sinus and induces HEV-like structures in the spleen. Blood 110:7, pages 2381-2389.
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Il-Rae Cho, Sunam Jeong, Byung Hak Jhun, Won G. An, BokSoo Lee, Youn-Tae Kwak, Sun-Hwa Lee, Jae U. Jung & Young-Hwa Chung. (2007) Activation of non-canonical NF-κB pathway mediated by STP-A11, an oncoprotein of Herpesvirus saimiri. Virology 359:1, pages 37-45.
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G Courtois & T D Gilmore. (2006) Mutations in the NF-κB signaling pathway: implications for human disease. Oncogene 25:51, pages 6831-6843.
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Emmanuel Dejardin. (2006) The alternative NF-κB pathway from biochemistry to biology: Pitfalls and promises for future drug development. Biochemical Pharmacology 72:9, pages 1161-1179.
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Shao-Cong Sun & Shoji Yamaoka. (2005) Activation of NF-κB by HTLV-I and implications for cell transformation. Oncogene 24:39, pages 5952-5964.
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Ruthie E Amir, Hans Haecker, Michael Karin & Aaron Ciechanover. (2003) Mechanism of processing of the NF-κB2 p100 precursor: identification of the specific polyubiquitin chain-anchoring lysine residue and analysis of the role of NEDD8-modification on the SCFβ-TrCP ubiquitin ligase. Oncogene 23:14, pages 2540-2547.
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Junghan Suh & Arnold B. Rabson. (2003) NF‐κB activation in human prostate cancer: Important mediator or epiphenomenon?. Journal of Cellular Biochemistry 91:1, pages 100-117.
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Sheryl M Gough, Margaret McDonald, Xiao-Ning Chen, Julie R Korenberg, Antonino Neri, Tomas Kahn, Michael R Eccles & Christine M Morris. (2003) Refined physical map of the human PAX2/HOX11/NFKB2 cancer gene region at 10q24 and relocalization of the HPV6AI1 viral integration site to 14q13.3-q21.1. BMC Genomics 4:1.
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Gongxian Liao & Shao-Cong Sun. (2003) Regulation of NF-κB2/p100 processing by its nuclear shuttling. Oncogene 22:31, pages 4868-4874.
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Abraham Fong, Minying Zhang, John Neely & Shao-Cong Sun. (2002) S9, a 19 S Proteasome Subunit Interacting with Ubiquitinated NF-κB2/p100. Journal of Biological Chemistry 277:43, pages 40697-40702.
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Takeshi Suzuki, Haifa Shen, Keiko Akagi, Herbert C Morse, James D Malley, Daniel Q Naiman, Nancy A Jenkins & Neal G Copeland. (2002) New genes involved in cancer identified by retroviral tagging. Nature Genetics 32:1, pages 166-174.
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Henry Pitot & Daniel Loeb. 2002. Fundamentals of Oncology, Revised and Expanded. Fundamentals of Oncology, Revised and Expanded 643 695 .

Nancie J. Solan, Hiroko Miyoshi, Eva M. Carmona, Gary D. Bren & Carlos V. Paya. (2002) RelB Cellular Regulation and Transcriptional Activity Are Regulated by p100. Journal of Biological Chemistry 277:2, pages 1405-1418.
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Reinhard Dummer, Jorg Willers, Jivko Kamarashev, Mirjana Urosevic, Udo Dobbeling & Gunter Burg. (2000) Pathogenesis of Cutaneous Lymphomas. Seminars in Cutaneous Medicine and Surgery 19:2, pages 78-86.
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Kyoung-Eun Kim, Chunyan Gu, Sanjay Thakur, Eric Vieira, Jennifer C Lin & Arnold B Rabson. (2000) Transcriptional regulatory effects of lymphoma-associated NFKB2/lyt10 protooncogenes. Oncogene 19:10, pages 1334-1345.
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Marina Heusch, Li Lin, Romas Geleziunas & Warner C Greene. (1999) The generation of nfkb2 p52: mechanism and efficiency. Oncogene 18:46, pages 6201-6208.
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P.M. Watt, P.R. Ranford & U.R. Kees. (1999) Sequence of 10q24 locus surrounding the HOX11 oncogene reveals a new gene HUG1 expressed in a T-ALL cell line. Gene 234:1, pages 169-176.
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Guido Franzoso, Louise Carlson, Ljiljana Poljak, Elizabeth W. Shores, Suzanne Epstein, Antonio Leonardi, Alex Grinberg, Tom Tran, Tanya Scharton-Kersten, Miriam Anver, Paul Love, Keith Brown & Ulrich Siebenlist. (1998) Mice Deficient in Nuclear Factor (NF)-κB/p52 Present with Defects in Humoral Responses, Germinal Center Reactions, and Splenic Microarchitecture. The Journal of Experimental Medicine 187:2, pages 147-159.
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The Involvement of the Candidate Proto-Oncogene NFKB2/lyt-10 in Lymphoid Malignancies

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The Involvement of the Candidate Proto-Oncogene NFKB2/lyt-10 in Lymphoid Malignancies

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