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Original Article

Addition of Etoposide to Initial Therapy of Adult Acute Lymphoblastic Leukemia: A Combined Clinicaland Laboratory Study

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Pages 71-83 | Received 20 Dec 1995, Published online: 01 Jul 2009

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Scott H. Kaufmann, Steven D. Gore, Carole B. Miller, Richard J. Jones, Leonard A. Zwelling, Erasmus Schneider, Philip J. Burke & Judith E. Karp. (1998) Topoisomerase II and the Response to Antileukemic Therapy. Leukemia & Lymphoma 29:3-4, pages 217-237.
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Vandana Singh, Pegah Johansson, Elina Ekedahl, Yii-Lih Lin, Ola Hammarsten & Fredrik Westerlund. (2022) Quantification of single-strand DNA lesions caused by the topoisomerase II poison etoposide using single DNA molecule imaging. Biochemical and Biophysical Research Communications 594, pages 57-62.
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Xavier Thomas. 2010. Leukemias: Principles and Practice of Therapy. Leukemias: Principles and Practice of Therapy 193 216 .
Wolfgang Hiddemann, Heinz Huber & Claus R. BartramD. Hoelzer, N. Gökbuget & M. Schrappe. 2004. Die Onkologie. Die Onkologie 1917 1952 .
Xue Wei Meng, Joya Chandra, David Loegering, Keri Van Becelaere, Timothy J. Kottke, Steven D. Gore, Judith E. Karp, Judy Sebolt-Leopold & Scott H. Kaufmann. (2003) Central Role of Fas-associated Death Domain Protein in Apoptosis Induction by the Mitogen-activated Protein Kinase Kinase Inhibitor CI-1040 (PD184352) in Acute Lymphocytic Leukemia Cells in Vitro. Journal of Biological Chemistry 278:47, pages 47326-47339.
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E.M. Sotomayor, S. Piantadosi, C.B. Miller, J.E. Karp, R.J. Jones, S.D. Rowley, S.H. Kaufmann, H. Braine, P.J. Burke & S.D. Gore. (2002) Long-term follow-up of intensive ara-C-based chemotherapy followed by bone marrow transplantation for adult acute lymphoblastic leukemia: impact of induction Ara-C dose and post-remission therapy. Leukemia Research 26:5, pages 461-471.
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Phyllis A. SvingenJudith E. KarpStan KrajewskiPeter W. MesnerJrJrSteven D. GorePhilip J. BurkeJohn C. ReedYuri A. LazebnikScott H. Kaufmann. (2000) Evaluation of Apaf-1 and procaspases-2, -3, -7, -8, and -9 as potential prognostic markers in acute leukemia. Blood 96:12, pages 3922-3931.
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K Padget, ADJ Pearson & CA Austin. (2000) Quantitation of DNA topoisomerase IIα and β in human leukaemia cells by immunoblotting. Leukemia 14:11, pages 1997-2005.
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Anne-Marie C. Dingemans, Herbert M. Pinedo & Giuseppe Giaccone. (1998) Clinical resistance to topoisomerase-targeted drugs. Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression 1400:1-3, pages 275-288.
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Scott H. KaufmannJudith E. KarpPhyllis A. SvingenStan KrajewskiPhilip J. BurkeSteven D. GoreJohn C. Reed. (1998) Elevated Expression of the Apoptotic Regulator Mcl-1 at the Time of Leukemic Relapse. Blood 91:3, pages 991-1000.
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Scott H. KaufmannPhyllis A. SvingenSteven D. GoreDeborah K. ArmstrongYung-Chi ChengEric K. Rowinsky. (1997) Altered Formation of Topotecan-Stabilized Topoisomerase I-DNA Adducts in Human Leukemia Cells. Blood 89:6, pages 2098-2104.
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