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Original Article

TP53 Mutations in Myelodysplastic Syndrome

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Pages 417-422 | Received 02 Feb 1996, Published online: 01 Jul 2009

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Joyce J Ou & Adam Bagg. (2009) Diagnostic challenges in the myelodysplastic syndromes: the current and future role of genetic and immunophenotypic studies. Expert Opinion on Medical Diagnostics 3:3, pages 275-291.
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Articles from other publishers (26)

Iwona Kwiecień, Elżbieta Rutkowska, Krzysztof Gawroński, Katarzyna Kulik, Alicja Dudzik, Agata Zakrzewska, Agata Raniszewska, Waldemar Sawicki & Piotr Rzepecki. (2023) Usefulness of New Neutrophil-Related Hematologic Parameters in Patients with Myelodysplastic Syndrome. Cancers 15:9, pages 2488.
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Heba Alkhatabi, Elrashed B. Yasin, Zeenat Mirza, Raed Alserihi, Raed Felimban, Aisha Elaimi, Manal Shaabad, Lina Alharbi, Hameeda Ahmed, Abdulrahman M. Alameer, Abdullah Ebraheem Mathkoor & Ahmed Salleh Barefah. (2022) TP53 Expression and Mutational Analysis in Hematological Malignancy in Jeddah, Saudi Arabia. Diagnostics 12:3, pages 724.
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Satoshi Nishiwaki, Masafumi Ito, Rie Watarai, Shingo Okuno, Yasuhiko Harada, Satomi Yamamoto, Kotaro Suzuki, Shingo Kurahashi, Toshihiro Iwasaki & Isamu Sugiura. (2016) A new prognostic index to make short-term prognoses in MDS patients treated with azacitidine: A combination of p53 expression and cytogenetics. Leukemia Research 41, pages 21-26.
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Marcus M. Schittenhelm, Barbara Illing, Figen Ahmut, Katharina Henriette Rasp, Gunnar Blumenstock, Konstanze Döhner, Charles D. Lopez & Kerstin M. Kampa-Schittenhelm. (2013) Attenuated Expression of Apoptosis Stimulating Protein of p53-2 (ASPP2) in Human Acute Leukemia Is Associated with Therapy Failure. PLoS ONE 8:11, pages e80193.
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H. Joachim Deeg, David T. Bowen, Steven D. Gore, Torsten Haferlach, Michelle M. Le Beau & Charlotte NiemeyerHarold J. Olney & Michelle M. Le Beau. 2013. Myelodysplastic Syndromes. Myelodysplastic Syndromes 41 72 .
Martin JäderstenLeonie SaftAlexander SmithAustin KulasekararajSabine PomplunGudrun GöhringAnette HedlundRobert HastBrigitte SchlegelbergerAnna PorwitEva Hellström-LindbergGhulam J. Mufti. (2011) TP53 Mutations in Low-Risk Myelodysplastic Syndromes With del(5q) Predict Disease Progression . Journal of Clinical Oncology 29:15, pages 1971-1979.
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David R. Head & Katherine S. Hamilton. 2011. Hematopathology. Hematopathology 656 671 .
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Petra A. Link, Maria R. Baer, Smitha R. James, David A. Jones & Adam R. Karpf. (2008) p53-Inducible Ribonucleotide Reductase ( p53R2/RRM2B ) Is a DNA Hypomethylation–Independent Decitabine Gene Target That Correlates with Clinical Response in Myelodysplastic Syndrome/Acute Myelogenous Leukemia . Cancer Research 68:22, pages 9358-9366.
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Takashi Iwasaki, Masashi Murakami, Chiho Sugisaki, Sayaka Sobue, Haruhiko Ohashi, Haruhiko Asano, Motoshi Suzuki, Shigeo Nakamura, Masafumi Ito & Takashi Murate. (2008) Characterization of myelodysplastic syndrome and aplastic anemia by immunostaining of p53 and hemoglobin F and karyotype analysis: Differential diagnosis between refractory anemia and aplastic anemia. Pathology International 58:6, pages 353-360.
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Anna D. Panani & Charis Roussos. (2006) Cytogenetic aspects of adult primary myelodysplastic syndromes: Clinical implications. Cancer Letters 235:2, pages 177-190.
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H. J. Deeg, D. T. Bowen, S. D. Gore, T. Haferlach, M. M. Le Beau & C. NiemeyerHarold J. Olney & Michelle M. Le Beau. 2006. Hematologic Malignancies: Myelodysplastic Syndromes. Hematologic Malignancies: Myelodysplastic Syndromes 55 79 .
Harold J. Olney & Michelle M. Le Beau. 2009. Myelodysplastic Syndromes. Myelodysplastic Syndromes 95 128 .
David P. Steensma & Alan F. List. (2005) Genetic Testing in the Myelodysplastic Syndromes: Molecular Insights Into Hematologic Diversity. Mayo Clinic Proceedings 80:5, pages 681-698.
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Kageaki KURIBAYASHI, Takuya MATSUNAGA, Toshio SAKAI, Yuko WADA, Kumiko TATENO, Kazuyuki MURASE, Akihito FUJIMI, Rishu TAKIMOTO, Takeshi TERUI, Junji KATO, Aya SASAKI, Masaaki SATOH & Yoshiro NIITSU. (2005) A Patient with TP53 Germline Mutation Developed Bowen’s Disease and Myelodysplastic Syndrome with Myelofibrosis after Chemotherapy against Ovarian Cancer. Internal Medicine 44:5, pages 490-495.
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Mitsushige Nakao, Shigeo Horiike, Yoko Fukushima-Nakase, Motohiro Nishimura, Yasuko Fujita, Masafumi Taniwaki & Tsukasa Okuda. (2004) Novel loss-of-function mutations of the haematopoiesis-related transcription factor, acute myeloid leukaemia 1/runt-related transcription factor 1, detected in acute myeloblastic leukaemia and myelodysplastic syndrome. British Journal of Haematology 125:6, pages 709-719.
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David P Steensma & Ayalew Tefferi. (2003) The myelodysplastic syndrome(s): a perspective and review highlighting current controversies. Leukemia Research 27:2, pages 95-120.
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Naofumi Fukuda, Kenji Shinohara, Ituro Ota, Kazuhiko Muraki & Yoko Shimohakamada. (2018) Therapy-Related Myelodysplastic Syndrome in a Case of Cutaneous Adult T-Cell Lymphoma. International Journal of Hematology 75:1, pages 67-71.
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Patricia D. CastroJan C. LiangLalitha Nagarajan. (2000) Deletions of chromosome 5q13.3 and 17p loci cooperate in myeloid neoplasms. Blood 95:6, pages 2138-2143.
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Yuri Sasai, Shigeo Horiike, Shinichi Misawa, Hiroto Kaneko, Miyako Kobayashi, Hiroshi Fujii, Kei Kashima & Masafumi Taniwaki. (1999) Genotype of glutathione S-transferase and other genetic configurations in myelodysplasia. Leukemia Research 23:11, pages 975-981.
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Hisashi Kawabata, Atae Utsunomiya, Shuichi Hanada, Torahiko Makino, Yoshifusa Takatsuka, Shogo Takeuchi, Shinsuke Suzuki, Junji Suzumiya, Kouichi Ohshima & Shigeo Horiike. (2002) Myelodysplastic syndrome in a patient with adult T‐cell leukaemia. British Journal of Haematology 106:3, pages 702-705.
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Masayuki Kikukawa, Naoto Aoki, Yoshimitu Sakamoto & Mayumi Mori. (1999) Study of p53 in Elderly Patients with Myelodysplastic Syndromes by Immunohistochemistry and DNA Analysis. The American Journal of Pathology 155:3, pages 717-721.
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Thoas FioretosBodil StrömbeckTherese SandbergBertil JohanssonRolf BillströmÅke BorgPer-Gunnar NilssonHerman Van Den BergheAnne HagemeijerFelix MitelmanMattias Höglund. (1999) Isochromosome 17q in Blast Crisis of Chronic Myeloid Leukemia and in Other Hematologic Malignancies Is the Result of Clustered Breakpoints in 17p11 and Is Not Associated With Coding TP53 Mutations. Blood 94:1, pages 225-232.
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Shinichi Misawa, Shigeo Horiike, Hiroto Kaneko, Yuri Sasai, Yutaka Ueda, Makoto Nakao, Shouhei Yokota, Masafumi Taniwaki, Hiroshi Fujii, Hitoshi Nakagawa, Shouichirou Tsuda & Kei Kashima. (1998) Significance of chromosomal alterations and mutations of the N-RAS and TP53 genes in relation to leukemogenesis of acute myeloid leukemia. Leukemia Research 22:7, pages 631-637.
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Cristina Mecucci. (1998) Molecular features of primary MDS with cytogenetic changes. Leukemia Research 22:4, pages 293-302.
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Paul G. Ekert & David L. Vaux. (1997) 8 Apoptosis, haemopoiesis and leukaemogenesis. Baillière's Clinical Haematology 10:3, pages 561-576.
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