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Leukemia & Lymphoma Volume 24, 1997 - Issue 3-4
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Original Article

Bcl-2 Expression in Acute Myeloblastic Leukaemia: Relationship with Autonomous Growth and CD34 Antigen Expression

D. A. Bradbury Department of Haematology, Medical Research Centre, City Hospital, Nottingham and the University of Nottingham, Nottingham, England, UK
,
Y. M. Zhu Department of Haematology, Medical Research Centre, City Hospital, Nottingham and the University of Nottingham, Nottingham, England, UK
&
N. H. Russell Department of Haematology, Medical Research Centre, City Hospital, Nottingham and the University of Nottingham, Nottingham, England, UK
Pages 221-228 | Received 29 Apr 1996, Published online: 01 Jul 2009

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Maria Ilaria Del Principe, Giovanni Del Poeta, Adriano Venditti, Francesco Buccisano, Luca Maurillo, Carla Mazzone, Antonio Bruno, Benedetta Neri, Maria Irno Consalvo, Francesco Lo Coco & Sergio Amadori. (2005) Apoptosis and immaturity in acute myeloid leukemia. Hematology 10:1, pages 25-34.
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Rosangela Invernizzi, Alessandro Pecci, Laura Bellotti & Edoardo Ascari. (2001) Expression of p53, Bcl-2 and Ras Oncoproteins and Apoptosis Levels in Acute Leukaemias and Myelodysplastic Syndromes. Leukemia & Lymphoma 42:3, pages 481-489.
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Kaishan Liu, Karl-Anton Kreuzer, Ulrich Lass & Christian Andreas Schmidt. (2005) Assessment of chemosensitivity by monitoring bcl-2 transcript kinetics in acute myeloid leukemias. Hematological Oncology 23:2, pages 68-72.
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Pier Luigi Tazzari, Alessandra Cappellini, Tiziana Grafone, Irina Mantovani, Francesca Ricci, Anna Maria Billi, Emanuela Ottaviani, Roberto Conte, Giovanni Martinelli & Alberto M. Martelli. (2004) Detection of serine 473 phosphorylated Akt in acute myeloid leukaemia blasts by flow cytometry. British Journal of Haematology 126:5, pages 675-681.
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H.T Hassan. (2004) Ajoene (natural garlic compound): a new anti-leukaemia agent for AML therapy. Leukemia Research 28:7, pages 667-671.
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Theocharis Panaretakis, Katja Pokrovskaja, Maria C Shoshan & Dan Grandér. (2003) Interferon-α-induced apoptosis in U266 cells is associated with activation of the proapoptotic Bcl-2 family members Bak and Bax. Oncogene 22:29, pages 4543-4556.
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Delphine Boudard, Christian Vasselon, Marie‐Françoise Berthéas, Jérôme Jaubert, Christiane Mounier, Jacqueline Reynaud, Annie Viallet, Sylviane Chautard, Denis Guyotat & Lydia Campos. (2002) Expression and prognostic significance of Bcl‐2 family proteins in myelodysplastic syndromes. American Journal of Hematology 70:2, pages 115-125.
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Pier Luigi Tazzari, Alessandra Cappellini, Roberta Bortul, Francesca Ricci, Anna Maria Billi, Giovanna Tabellini, Roberto Conte & Alberto M. Martelli. (2002) Flow cytometric detection of total and serine 473 phosphorylated Akt. Journal of Cellular Biochemistry 86:4, pages 704-715.
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Myriam Alcalay, Annette Orleth, Carla Sebastiani, Natalia Meani, Ferdinando Chiaradonna, Cristina Casciari, Maria Teresa Sciurpi, Vania Gelmetti, Daniela Riganelli, Saverio Minucci, Marta Fagioli & Pier Giuseppe Pelicci. (2001) Common themes in the pathogenesis of acute myeloid leukemia. Oncogene 20:40, pages 5680-5694.
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Jane E. Parker & Ghulam J. Mufti. (2001) The Role of Apoptosis in the Pathogenesis of the Myelodysplastic Syndromes. International Journal of Hematology 73:4, pages 416-428.
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Øystein Bruserud, Bjørn Tore Gjertsen, Brynjar Foss & Tien‐Sheng Huang. (2009) New Strategies in the Treatment of Acute Myelogenous Leukemia (AML): In Vitro Culture of AML Cells—The Present Use in Experimental Studies and the Possible Importance for Future Therapeutic Approaches. STEM CELLS 19:1, pages 1-11.
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Nina Ruth Lewis, Monica Pallis & Nigel H Russell. (2000) Fas receptor-Fas ligand system is independent of both CD34 status and chemosensitivity in acute myeloid leukemia. Experimental Hematology 28:5, pages 535-542.
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N. Ahmed, L. Laverick, J. Sammons, K.R.N. Baumforth & H.T. Hassan. (1999) Effect of all-trans retinoic acid on chemotherapy induced apoptosis and down-regulation of Bc1-2 in human myeloid leukaemia CD34 positive cells. Leukemia Research 23:8, pages 741-749.
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Huei-Mei HuangJian-Chiuan LiYueh-Chun HsiehHsin-Fang Yang-YenJeffrey Jong-Young Yen. (1999) Optimal Proliferation of a Hematopoietic Progenitor Cell Line Requires Either Costimulation With Stem Cell Factor or Increase of Receptor Expression That Can Be Replaced by Overexpression of Bcl-2. Blood 93:8, pages 2569-2577.
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Claudia Bincolettu, Sara T. O. Saad, Elizabeth Soares da Silva & Mary L. S. Queiroz. (2009) Haematopoietic response and bcl ‐2 expression in patients with acute myeloid leukaemia . European Journal of Haematology 62:1, pages 38-42.
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Parker, Fishlock, Mijovic, Czepulkowski, Pagliuca & Mufti. (2002) ‘Low‐risk’ myelodysplastic syndrome is associated with excessive apoptosis and an increased ratio of pro‐ versus anti‐apoptotic bcl‐2‐related proteins. British Journal of Haematology 103:4, pages 1075-1082.
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Parker & Mufti. (2001) Ineffective haemopoiesis and apoptosis in myelodysplastic syndromes. British Journal of Haematology 101:2, pages 220-230.
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