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Leukemia & Lymphoma Volume 31, 1998 - Issue 5-6
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Original Article

Blocking Interleukin-6 Activity with Chimeric Anti-IL6 Monoclonal Antibodies in Multiple Myeloma: Effects on Soluble IL6 Receptor and Soluble gp130

H.C.T. Van Zaanen Department of Hematology, Academic Medical Center, Amsterdam, The Netherlands
,
H. M. Lokhorst Dep. of Hematology, The Netherlands
,
L. A. Aarden Academic Hospital Utrecht CLB, Amsterdam and Centocor, Leiden
,
H. J.A.M. Rensink Academic Hospital Utrecht CLB, Amsterdam and Centocor, Leiden
,
S. O. Warnaar Academic Hospital Utrecht CLB, Amsterdam and Centocor, Leiden
&
M. H.J. Van Oers Department of Hematology, Academic Medical Center, Amsterdam, The Netherlands
Pages 551-558 | Accepted 01 Mar 1998, Published online: 01 Jul 2009

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Flora Zagouri, Evangelos Terpos, Efstathios Kastritis & Meletios A. Dimopoulos. (2016) Emerging antibodies for the treatment of multiple myeloma. Expert Opinion on Emerging Drugs 21:2, pages 225-237.
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Takuya Ohtani, Katsuhiko Ishihara, Toru Atsumi, Yuichi Yoshida, Keigo Nishida, Masahiro Narimatsu, Takahiro Shirogane, Masahiko Hibi & Toshio Hirano. (2000) gp130-mediated signalling as a therapeutic target. Emerging Therapeutic Targets 4:4, pages 459-479.
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Articles from other publishers (18)

Hanley Abramson. (2018) Monoclonal Antibodies for the Treatment of Multiple Myeloma: An Update. International Journal of Molecular Sciences 19:12, pages 3924.
Crossref
Yu Zhou & James D. Marks. 2016. Biosimilars of Monoclonal Antibodies. Biosimilars of Monoclonal Antibodies 85 111 .
Eric Angevin, Josep Tabernero, Elena Elez, Steven J. Cohen, Rastilav Bahleda, Jean-Luc van Laethem, Christian Ottensmeier, Jose A. Lopez-Martin, Sally Clive, Florence Joly, Isabelle Ray-Coquard, Luc Dirix, Jean-Pascal Machiels, Neil Steven, Manjula Reddy, Brett Hall, Thomas A. Puchalski, Rajesh Bandekar, Helgi van de Velde, Brenda Tromp, Jessica Vermeulen & Razelle Kurzrock. (2014) A Phase I/II, Multiple-Dose, Dose-Escalation Study of Siltuximab, an Anti-Interleukin-6 Monoclonal Antibody, in Patients with Advanced Solid Tumors. Clinical Cancer Research 20:8, pages 2192-2204.
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Razelle Kurzrock, Peter M. Voorhees, Corey Casper, Richard R. Furman, Luis Fayad, Sagar Lonial, Hossein Borghaei, Sundar Jagannath, Lubomir Sokol, Saad Z. Usmani, Helgi van de Velde, Xiang Qin, Thomas A. Puchalski, Brett Hall, Manjula Reddy, Ming Qi & Frits van Rhee. (2013) A Phase I, Open-Label Study of Siltuximab, an Anti–IL-6 Monoclonal Antibody, in Patients with B-cell Non-Hodgkin Lymphoma, Multiple Myeloma, or Castleman Disease. Clinical Cancer Research 19:13, pages 3659-3670.
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Alessandro Allegra, Giuseppa Penna, Andrea Alonci, Sabina Russo, Bruna Greve, Vanessa Innao, Viviana Minardi & Caterina Musolino. (2013) Monoclonal antibodies: potential new therapeutic treatment against multiple myeloma. European Journal of Haematology 90:6, pages 441-468.
Crossref
Yu-Tzu Tai. 2013. Advances in Biology and Therapy of Multiple Myeloma. Advances in Biology and Therapy of Multiple Myeloma 43 71 .
Elisabeth Ersvær, Guro Kristin Melve & Øystein Bruserud. (2011) Future perspectives: should Th17 cells be considered as a possible therapeutic target in acute myeloid leukemia patients receiving allogeneic stem cell transplantation?. Cancer Immunology, Immunotherapy 60:12, pages 1669-1681.
Crossref
Yu-Tzu Tai & Kenneth C. Anderson. (2011) Antibody-Based Therapies in Multiple Myeloma. Bone Marrow Research 2011, pages 1-14.
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Frits van RheeLuis FayadPeter VoorheesRichard FurmanSagar LonialHossein BorghaeiLubomir SokolJulie CrawfordMark CornfeldMing QiXiang QinJennifer HerringCorey CasperRazelle Kurzrock. (2010) Siltuximab, a Novel Anti–Interleukin-6 Monoclonal Antibody, for Castleman's Disease. Journal of Clinical Oncology 28:23, pages 3701-3708.
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Anne Catherine SprynskiDirk HoseLaurent CaillotThierry RémeJohn D. ShaughnessyJrJrBart BarlogieAnja SeckingerJérôme MoreauxMichael HundemerMichel JourdanTobias MeißnerAnna Jauch, Karène MahtoukAlboukadel KassambaraUta BertschJean François Rossi, Hartmut GoldschmidtBernard Klein. (2009) The role of IGF-1 as a major growth factor for myeloma cell lines and the prognostic relevance of the expression of its receptor. Blood 113:19, pages 4614-4626.
Crossref
Walter M. Lewko & Robert K. Oldham. 2009. Principles of Cancer Biotherapy. Principles of Cancer Biotherapy 155 276 .
Nikhil C. Munshi & Yu-Tzu Tai. 2009. Myeloma Therapy. Myeloma Therapy 167 202 .
Suzanne Lentzsch. (2007) Death by rafting. Blood 110:8, pages 2791-2792.
Crossref
Mohamed H. Zaki, Jeffrey A. Nemeth & Mohit Trikha. (2004) CNTO 328, a monoclonal antibody to IL-6, inhibits human tumor-induced cachexia in nude mice. International Journal of Cancer 111:4, pages 592-595.
Crossref
Heinz Ludwig & Niklas Zojer. 2004. Biology and Management of Multiple Myeloma. Biology and Management of Multiple Myeloma 223 249 .
Walter M. Lewko & Robert K. Oldham. 2003. Principles of Cancer Biotherapy. Principles of Cancer Biotherapy 183 299 .
E Kovacs & J.J Kuehn. (2002) Measurements of IL-6, soluble IL-6 receptor and soluble gp130 in sera of B-cell lymphoma patients. Does Viscum album treatment affect these parameters?. Biomedicine & Pharmacotherapy 56:3, pages 152-158.
Crossref
E Kovacs. (2001) Investigation of interleukin-6 (IL-6), soluble IL-6 receptor (sIL-6R) and soluble gp130 (sgp130) in sera of cancer patients. Biomedicine & Pharmacotherapy 55:7, pages 391-396.
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