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Joseph Ciccolini, Cindy Serdjebi, Hau Le Thi Thu, Bruno Lacarelle, Gerard Milano & Raphaelle Fanciullino. (2016) Nucleoside analogs: ready to enter the era of precision medicine?. Expert Opinion on Drug Metabolism & Toxicology 12:8, pages 865-877.
Read now
Read now
Emeline Cros, Lars Jordheim, Charles Dumontet & Carlos M Galmarini. (2004) Problems Related to Resistance to Cytarabine in Acute Myeloid Leukemia. Leukemia & Lymphoma 45:6, pages 1123-1132.
Read now
Read now
Kourosh Lotfi, Gunnar Juliusson & Freidoun Albertioni. (2003) Pharmacological Basis for Cladribine Resistance. Leukemia & Lymphoma 44:10, pages 1705-1712.
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Articles from other publishers (38)
Biao Wu, Zhengwei Jenny Mao, Zhi Wang, Pin Wu, Hongyu Huang, Wenjun Zhao, Lei Zhang, Zhou Zhang, Hongchao Yin, Robert Peter Gale & Bin Yin. (2021) Deoxycytidine Kinase (DCK) Mutations in Human Acute Myeloid Leukemia Resistant to Cytarabine. Acta Haematologica 144:5, pages 534-541.
Crossref
Crossref
Werner J. Geldenhuys, Rajesh R. Nair, Debbie Piktel, Karen H. Martin & Laura F. Gibson. (2019) The MitoNEET Ligand NL-1 Mediates Antileukemic Activity in Drug-Resistant B-Cell Acute Lymphoblastic Leukemia. Journal of Pharmacology and Experimental Therapeutics 370:1, pages 25-34.
Crossref
Crossref
Svetlana V. Vasilyeva, Alexander A. Shtil, Albina S. Petrova, Sergei M. Balakhnin, Polina Y. Achigecheva, Dmitry A. Stetsenko & Vladimir N. Silnikov. (2017) Conjugates of phosphorylated zalcitabine and lamivudine with SiO2 nanoparticles: Synthesis by CuAAC click chemistry and preliminary assessment of anti-HIV and antiproliferative activity. Bioorganic & Medicinal Chemistry 25:5, pages 1696-1702.
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Crossref
Pornpun Sripornsawan, Yasuhiro Okamoto, Takuro Nishikawa, Yuichi Kodama, Yuni Yamaki, Koichiro Kurauchi, Takayuki Tanabe, Shunsuke Nakagawa, Yuichi Shinkoda, Naoko Imuta & Yoshifumi Kawano. (2017) Gene expression ratio as a predictive determinant of nelarabine chemosensitivity in T-lymphoblastic leukemia/lymphoma. Pediatric Blood & Cancer 64:2, pages 250-253.
Crossref
Crossref
Nico Lachmann, Sebastian Brennig & Thomas Moritz. 2014. Gene Therapy of Cancer. Gene Therapy of Cancer
423
440
.
Thulani H. Senanayake, Galya Warren, Xin Wei & Serguei V. Vinogradov. (2013) Application of activated nucleoside analogs for the treatment of drug-resistant tumors by oral delivery of nanogel-drug conjugates. Journal of Controlled Release 167:2, pages 200-209.
Crossref
Crossref
Ashkan Emadi & Judith E Karp. (2012) The clinically relevant pharmacogenomic changes in acute myelogenous leukemia. Pharmacogenomics 13:11, pages 1257-1269.
Crossref
Crossref
Steven W. Paugh, Mary V. Relling & William E. Evans. 2013. Childhood Leukemias. Childhood Leukemias
309
331
.
Yu Fukuda & John D. Schuetz. (2012) ABC transporters and their role in nucleoside and nucleotide drug resistance. Biochemical Pharmacology 83:8, pages 1073-1083.
Crossref
Crossref
Irene HommingaC. Michel ZwaanChantal Y. Manz, Cynthia Parker, Shanta Bantia, Willem Korstiaan SmitsFiona Higginbotham, Rob PietersJules P. P. Meijerink. (2011) In vitro efficacy of forodesine and nelarabine (ara-G) in pediatric leukemia. Blood 118:8, pages 2184-2190.
Crossref
Crossref
Noël J.-M. Raynal, Louise F. Momparler, Georges E. Rivard & Richard L. Momparler. (2011) 3-Deazauridine enhances the antileukemic action of 5-aza-2′-deoxycytidine and targets drug-resistance due to deficiency in deoxycytidine kinase. Leukemia Research 35:1, pages 110-118.
Crossref
Crossref
Steven W Paugh, Gabriele Stocco & William E Evans. (2010) Pharmacogenomics in pediatric leukemia. Current Opinion in Pediatrics 22:6, pages 703-710.
Crossref
Crossref
Rodolphe Taby & Jean-Pierre J. Issa. (2010) Cancer Epigenetics. CA: A Cancer Journal for Clinicians 60:6, pages 376-392.
Crossref
Crossref
Robert F. Wynn. 2010. Pediatric Hematology and Oncology. Pediatric Hematology and Oncology
75
94
.
Jatinder K Lamba. (2009) Genetic factors influencing cytarabine therapy. Pharmacogenomics 10:10, pages 1657-1674.
Crossref
Crossref
Daniel J. DeAngelo. (2009) Nelarabine for the Treatment of Patients with Relapsed or Refractory T-cell Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma. Hematology/Oncology Clinics of North America 23:5, pages 1121-1135.
Crossref
Crossref
Taichun Qin, Jaroslav Jelinek, Jiali Si, Jingmin Shu & Jean-Pierre J. Issa. (2009) Mechanisms of resistance to 5-aza-2′-deoxycytidine in human cancer cell lines. Blood 113:3, pages 659-667.
Crossref
Crossref
Jatinder K. Lamba, Kristine Crews, Stanley Pounds, Erin G. Schuetz, Jessica Gresham, Varsha Gandhi, William Plunkett, Jeffrey Rubnitz & Raul Ribeiro. (2007) Pharmacogenetics of Deoxycytidine Kinase: Identification and Characterization of Novel Genetic Variants. Journal of Pharmacology and Experimental Therapeutics 323:3, pages 935-945.
Crossref
Crossref
Syu-ichi Kanno, Takako Hiura, Takaharu Ohtake, Kimiko Koiwai, Hiroyoshi Suzuki, Mayuko Ujibe & Masaaki Ishikawa. (2007) Characterization of resistance to cytosine arabinoside (Ara-C) in NALM-6 human B leukemia cells. Clinica Chimica Acta 377:1-2, pages 144-149.
Crossref
Crossref
Hitoshi Uga, Chikanori Kuramori, Akiko Ohta, Yasunori Tsuboi, Hiroshi Tanaka, Mamoru Hatakeyama, Yuki Yamaguchi, Takashi Takahashi, Masahiro Kizaki & Hiroshi Handa. (2006) A New Mechanism of Methotrexate Action Revealed by Target Screening with Affinity Beads. Molecular Pharmacology 70:5, pages 1832-1839.
Crossref
Crossref
Lars Petter Jordheim, Carlos M. Galmarini & Charles Dumontet. (2006) Gemcitabine resistance due to deoxycytidine kinase deficiency can be reverted by fruitfly deoxynucleoside kinase, DmdNK, in human uterine sarcoma cells. Cancer Chemotherapy and Pharmacology 58:4, pages 547-554.
Crossref
Crossref
Kourosh Lotfi, Karin Karlsson, Anna Fyrberg, Gunnar Juliusson, Viggo Jonsson, Curt Peterson, Staffan Eriksson & Freidoun Albertioni. (2006) The pattern of deoxycytidine- and deoxyguanosine kinase activity in relation to messenger RNA expression in blood cells from untreated patients with B-cell chronic lymphocytic leukemia. Biochemical Pharmacology 71:6, pages 882-890.
Crossref
Crossref
Shinji Kishi, William E. Evans & Mary V. Relling. 2010. Childhood Leukemias. Childhood Leukemias
391
413
.
I Hubeek, R W Stam, G J Peters, R Broekhuizen, J P P Meijerink, E R van Wering, B E S Gibson, U Creutzig, C M Zwaan, J Cloos, D J Kuik, R Pieters & G J L Kaspers. (2005) The human equilibrative nucleoside transporter 1 mediates in vitro cytarabine sensitivity in childhood acute myeloid leukaemia. British Journal of Cancer 93:12, pages 1388-1394.
Crossref
Crossref
Stacey L. BergSusan M. BlaneyMeenakshi DevidasTom A. LampkinAnthony MurgoMark BernsteinAmy BillettJoanne KurtzbergGreg ReamanPaul GaynonJames WhitlockMark KrailoMichael B. Harris. (2005) Phase II Study of Nelarabine (compound 506U78) in Children and Young Adults With Refractory T-Cell Malignancies: A Report From the Children’s Oncology Group. Journal of Clinical Oncology 23:15, pages 3376-3382.
Crossref
Crossref
Hiroyuki Achiwa, Tetsuya Oguri, Shigeki Sato, Hiroyoshi Maeda, Takashi Niimi & Ryuzo Ueda. (2005) Determinants of sensitivity and resistance to gemcitabine: The roles of human equilibrative nucleoside transporter 1 and deoxycytidine kinase in non‐small cell lung cancer. Cancer Science 95:9, pages 753-757.
Crossref
Crossref
Lars Petter Jordheim, Emeline Cros, Marie-Hélène Gouy, Carlos M. Galmarini, Suzanne Peyrottes, John Mackey, Christian Perigaud & Charles Dumontet. (2004) Characterization of a Gemcitabine-Resistant Murine Leukemic Cell Line. Clinical Cancer Research 10:16, pages 5614-5621.
Crossref
Crossref
Yubin Ge, Tanya L. Jensen, Larry H. Matherly & Jeffrey W. Taub. (2003) Physical and Functional Interactions between USF and Sp1 Proteins Regulate Human Deoxycytidine Kinase Promoter Activity. Journal of Biological Chemistry 278:50, pages 49901-49910.
Crossref
Crossref
C.L van der Wilt, J.R Kroep, W.J.P Loves, M.G Rots, C.J Van Groeningen, G.J Kaspers & G.J Peters. (2003) Expression of deoxycytidine kinase in leukaemic cells compared with solid tumour cell lines, liver metastases and normal liver. European Journal of Cancer 39:5, pages 691-697.
Crossref
Crossref
M. M. Van den Heuvel-Eibrink, E. A. C. Wiemer, M. Kuipers, R. Pieters & P. Sonneveld. 2003. Acute Leukemias IX. Acute Leukemias IX
232
238
.
Marjan J. T. Veuger, M. Willy Honders, Roel Willemze & Renée M. Y. Barge. (2002) Deoxycytidine kinase expression and activity in patients with resistant versus sensitive acute myeloid leukemia. European Journal of Haematology 69:3, pages 171-178.
Crossref
Crossref
E Månsson, E Liliemark, S Söderhäll, G Gustafsson, S Eriksson & F Albertioni. (2002) Real-time quantitative PCR assays for deoxycytidine kinase, deoxyguanosine kinase and 5’-nucleotidase mRNA measurement in cell lines and in patients with leukemia. Leukemia 16:3, pages 386-392.
Crossref
Crossref
Marjan J. T. Veuger, Mirjam H. M. Heemskerk, M. Willy Honders, Roel Willemze & Renée M. Y. Barge. (2002) Functional role of alternatively spliced deoxycytidine kinase in sensitivity to cytarabine of acute myeloid leukemic cells. Blood 99:4, pages 1373-1380.
Crossref
Crossref
Ming C. Cha & Kelly A. Meckling-Gill. (2002) Modifications of deoxycytidine kinase and deaminase activities by docosahexaenoic acid in normal and transformed rat fibroblasts. Biochemical Pharmacology 63:4, pages 717-723.
Crossref
Crossref
CM Galmarini, JR Mackey & C Dumontet. (2001) Nucleoside analogues: mechanisms of drug resistance and reversal strategies. Leukemia 15:6, pages 875-890.
Crossref
Crossref
MM van den Heuvel-Eibrink, EAC Wiemer, M Kuijpers, R Pieters & P Sonneveld. (2001) Absence of mutations in the deoxycytidine kinase (dCK) gene in patients with relapsed and/or refractory acute myeloid leukemia (AML). Leukemia 15:5, pages 855-856.
Crossref
Crossref
Zsolt Csapó, Mária Sasvári-Székely, Tatjana Spasokoukotskaja, Iannis Talianidis, Staffan Eriksson & Mária Staub. (2001) Activation of deoxycytidine kinase by inhibition of DNA synthesis in human lymphocytes11Abbreviations: dCK, deoxycytidine kinase; dTK, thymidine kinase; CdA, 2-chloro-2′-deoxyadenosine; araC, 1-β-D-arabinofuranosylcytosine; 3HdC, 2′-deoxy-[5-3H] cytidine; 3HdT, 2′-deoxy-[5-methyl-3H] thymidine; HL 60, human promyelocytic cell line; AML, acute myeloid leukaemia; PBMC, peripherial blood mononuclear cell; APC, aphidicolin; and DEAE, diethylaminoethyl.. Biochemical Pharmacology 61:2, pages 191-197.
Crossref
Crossref
Magnus Johansson, Ameli Norda & Anna Karlsson. (2000)
Conserved gene structure and transcription factor sites in the human and mouse deoxycytidine kinase genes
1
. FEBS Letters 487:2, pages 209-212.
Crossref
Crossref