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Review Article

High-Risk Myelodysplastic Syndromes and Hypermethylation of the p15Ink4B Gene

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Pages 9-18 | Received 10 Mar 1998, Published online: 01 Jul 2009

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Kavita Raj & Ghulam J Mufti. (2006) Azacytidine (Vidaza®) in the treatment of myelodysplastic syndromes. Therapeutics and Clinical Risk Management 2:4, pages 377-388.
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Tomoki Naoe, Yasuwki Nakano & Hitoshi Kiyoi. (2000) Leukemia Relapse Reconsidered from the Molecular Aspect. Leukemia & Lymphoma 37:5-6, pages 527-534.
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Sriram Sundaravel, Ulrich Steidl & Amittha Wickrema. (2021) Epigenetic modifiers in normal and aberrent erythropoeisis. Seminars in Hematology 58:1, pages 15-26.
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Zi-jun Xu, Chun-yan Tang, Jing-dong Zhou, Ji-chun Ma, Xiang-mei Wen, Zhao-qun Deng, Jia-yan Leng, Zhi-yuan Qiu, Jun Qian & Jiang Lin. (2019) SOX7 methylation is an independent prognostic factor in myelodysplastic syndromes. Pathology - Research and Practice 215:2, pages 322-328.
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Jixue Zou, Zhigang Zhou, Liping Wan, Yin Tong, Youwen Qin, Chun Wang & Kun Zhou. (2015) Targeting the Sonic Hedgehog-Gli1 Pathway as a Potential New Therapeutic Strategy for Myelodysplastic Syndromes. PLOS ONE 10:8, pages e0136843.
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Hsing-Chen Tsai & Stephen B Baylin. (2011) Cancer epigenetics: linking basic biology to clinical medicine. Cell Research 21:3, pages 502-517.
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Huong Thi Thanh TranHee Nam Kim, Il-Kwon LeeYeo-Kyeoung KimJae-Sook AhnDeok-Hwan YangJe-Jung LeeHyeoung-Joon Kim. (2011) DNA Methylation Changes Following 5-azacitidine Treatment in Patients with Myelodysplastic Syndrome. Journal of Korean Medical Science 26:2, pages 207.
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Lisa Pleyer, Daniel Neureiter, Victoria Faber & Richard Greil. 2010. Chronic Myeloid Neoplasias and Clonal Overlap Syndromes. Chronic Myeloid Neoplasias and Clonal Overlap Syndromes 153 222 .
Bruno Quesnel. (2009) Methyltransferases in myelodysplastic syndromes: Guilty or not guilty?. Leukemia Research 33:5, pages 601-602.
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Rebecca B. Klisovic, Wendy Stock, Spero Cataland, Marko I. Klisovic, Shujun Liu, William Blum, Margaret Green, Olatoyosi Odenike, Lucy Godley, Jennifer Vanden Burgt, Emily Van Laar, Michael Cullen, A. Robert Macleod, Jeffrey M. Besterman, Gregory K. Reid, John C. Byrd & Guido Marcucci. (2008) A Phase I Biological Study of MG98, an Oligodeoxynucleotide Antisense to DNA Methyltransferase 1, in Patients with High-Risk Myelodysplasia and Acute Myeloid Leukemia. Clinical Cancer Research 14:8, pages 2444-2449.
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K. Raj, A. Ho, J.D. Creamer, A.W.P. du Vivier, J.R. Salisbury & G.J. Mufti. (2007) Complete response of deep neutrophilic dermatosis associated with myelodysplastic syndrome to 5-azacytidine. British Journal of Dermatology 156:5, pages 1039-1041.
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Ha Thanh Nishino & Chung-Che Chang. (2005) Myelodysplastic Syndromes: Clinicopathologic Features, Pathobiology, and Molecular Pathogenesis. Archives of Pathology & Laboratory Medicine 129:10, pages 1299-1310.
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Peter A. Jones. (2005) Overview of Cancer Epigenetics. Seminars in Hematology 42, pages S3-S8.
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David P. Steensma & Alan F. List. (2005) Genetic Testing in the Myelodysplastic Syndromes: Molecular Insights Into Hematologic Diversity. Mayo Clinic Proceedings 80:5, pages 681-698.
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PETER A. JONES. (2003) Epigenetics in Carcinogenesis and Cancer Prevention. Annals of the New York Academy of Sciences 983:1, pages 213-219.
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Lewis R. SilvermanErin P. DemakosBercedis L. PetersonAlice B. KornblithJimmie C. HollandRosalie Odchimar-ReissigRichard M. StoneDouglas NelsonBayard L. PowellCarlos M. DeCastroJohn EllertonRichard A. LarsonCharles A. SchifferJames F. Holland. (2002) Randomized Controlled Trial of Azacitidine in Patients With the Myelodysplastic Syndrome: A Study of the Cancer and Leukemia Group B. Journal of Clinical Oncology 20:10, pages 2429-2440.
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David Mintzer & Adam Bagg. (2001) Clinical syndromes of transformation in clonal hematologic disorders. The American Journal of Medicine 111:6, pages 480-488.
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Rose Ann Padua, Angela McGlynn & Hugh McGlynn. 2001. Myelodysplastic Syndromes & Secondary Acute Myelogenous Leukemia. Myelodysplastic Syndromes & Secondary Acute Myelogenous Leukemia 111 157 .

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