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Original Article

Expression of Receptor Tyrosine Kinase HTK (Hepatoma Transmembrane Kinase) and HTK Ligand by Human Leukemia-Lymphoma Cell Lines

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Pages 371-376 | Accepted 30 Aug 1998, Published online: 01 Jul 2009

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Benjamin D. Ferguson, Maria S. Tretiakova, Mark W. Lingen, Parkash S. Gill & Ravi Salgia. (2014) Expression of the EPHB4 receptor tyrosine kinase in head and neck and renal malignancies – implications for solid tumors and potential for therapeutic inhibition. Growth Factors 32:6, pages 202-206.
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Mark G. Coulthard, Jason D. Lickliter, Nadesapillai Subanesan, Ke Chen, Graham C. Webb, Amanda J. Lowry, Simon Koblar, Cynthia D.K. Bottema & Andrew W. Boyd. (2001) Characterization of the EphA1 Receptor Tyrosine Kinase: Expression in Epithelial Tissues. Growth Factors 18:4, pages 303-317.
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Articles from other publishers (22)

Ioanna E. Stergiou, Stavros P. Papadakos, Anna Karyda, Ourania E. Tsitsilonis, Meletios-Athanasios Dimopoulos & Stamatios Theocharis. (2023) EPH/Ephrin Signaling in Normal Hematopoiesis and Hematologic Malignancies: Deciphering Their Intricate Role and Unraveling Possible New Therapeutic Targets. Cancers 15:15, pages 3963.
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Kalpana K. Bhanumathy, Amrutha Balagopal, Frederick S. Vizeacoumar, Franco J. Vizeacoumar, Andrew Freywald & Vincenzo Giambra. (2021) Protein Tyrosine Kinases: Their Roles and Their Targeting in Leukemia. Cancers 13:2, pages 184.
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Sara Charmsaz, Andrew M. Scott & Andrew W. Boyd. (2017) Targeted therapies in hematological malignancies using therapeutic monoclonal antibodies against Eph family receptors. Experimental Hematology 54, pages 31-39.
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Akil A. MerchantAparna JorapurAmy McManusRen LiuValery KrasnoperovParvesh ChaudhryMohan SinghLisa HartonMary AgajanianMiriam KimTimothy J. TricheJrJrBrian J. Druker, Jeffrey W. Tyner & Parkash S. Gill. (2017) EPHB4 is a therapeutic target in AML and promotes leukemia cell survival via AKT. Blood Advances 1:20, pages 1635-1644.
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S Charmsaz, F Al-Ejeh, T M Yeadon, K J Miller, F M Smith, B W Stringer, A S Moore, F-T Lee, L T Cooper, C Stylianou, G T Yarranton, J Woronicz, A M Scott, M Lackmann & A W Boyd. (2017) EphA3 as a target for antibody immunotherapy in acute lymphoblastic leukemia. Leukemia 31:8, pages 1779-1787.
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Sara Charmsaz, Kirrilee Beckett, Fiona M. Smith, Claudia Bruedigam, Andrew S. Moore, Fares Al-Ejeh, Steven W. Lane & Andrew W. Boyd. (2015) EphA2 Is a Therapy Target in EphA2-Positive Leukemias but Is Not Essential for Normal Hematopoiesis or Leukemia. PLOS ONE 10:6, pages e0130692.
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Alison Maddigan, Luke Truitt, Ryan Arsenault, Tanya Freywald, Odette Allonby, Jonathan Dean, Aru Narendran, Jim Xiang, Andrew Weng, Scott Napper & Andrew Freywald. (2011) EphB Receptors Trigger Akt Activation and Suppress Fas Receptor-Induced Apoptosis in Malignant T Lymphocytes. The Journal of Immunology 187:11, pages 5983-5994.
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Min-A Seol, In-Sun Chu, Mi-Jin Lee, Goung-Ran Yu, Xiang-Dan Cui, Baik-Hwan Cho, Eun-Kyung Ahn, Sun-Hee Leem, In-Hee Kim & Dae-Ghon Kim. (2011) Genome-wide expression patterns associated with oncogenesis and sarcomatous transdifferentation of cholangiocarcinoma. BMC Cancer 11:1.
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Mario Mancino, Elisabet Ametller, Pedro Gascón & Vanessa Almendro. (2011) The neuronal influence on tumor progression. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 1816:2, pages 105-118.
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Michael J. Ting, Bryan W. Day, Mark D. Spanevello & Andrew W. Boyd. (2010) Activation of ephrin A proteins influences hematopoietic stem cell adhesion and trafficking patterns. Experimental Hematology 38:11, pages 1087-1098.
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Luis M. Alonso-C, Eva Ma. Trinidad, Beatriz de Garcillan, Monica Ballesteros, Milagros Castellanos, Ignacio Cotillo, Juan J. Muñoz & Agustin G. Zapata. (2009) Expression profile of Eph receptors and ephrin ligands in healthy human B lymphocytes and chronic lymphocytic leukemia B-cells. Leukemia Research 33:3, pages 395-406.
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M. Tachibana, Y. Tonomoto, R. Hyakudomi, M. Hyakudomi, S. Hattori, S. Ueda, S. Kinugasa & H. Yoshimura. (2007) Expression and prognostic significance of EFNB2 and EphB4 genes in patients with oesophageal squamous cell carcinoma. Digestive and Liver Disease 39:8, pages 725-732.
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Rizwan Masood, S. Ram Kumar, Uttam K. Sinha, David L. Crowe, Valery Krasnoperov, Ramachandra K. Reddy, Sergey Zozulya, Jasbir Singh, Guangbin Xia, Daniel Broek, Axel H. Schönthal & Parkash S. Gill. (2006) EphB4 provides survival advantage to squamous cell carcinoma of the head and neck. International Journal of Cancer 119:6, pages 1236-1248.
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Qi‐Xiang Li, Philip Tan, Ning Ke & Flossie Wong‐Staal. 2006. Genomics in Cancer Drug Discovery and Development. Genomics in Cancer Drug Discovery and Development 103 143 .
Hongyu Luo, Guang Yu, Johanne Tremblay & Jiangping Wu. (2004) EphB6-null mutation results in compromised T cell function. Journal of Clinical Investigation 114:12, pages 1762-1773.
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Hanna Surawska, Patrick C. Ma & Ravi Salgia. (2004) The role of ephrins and Eph receptors in cancer. Cytokine & Growth Factor Reviews 15:6, pages 419-433.
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Guang Yu, Hongyu Luo, Yulian Wu & Jiangping Wu. (2003) Mouse EphrinB3 Augments T-cell Signaling and Responses to T-cell Receptor Ligation. Journal of Biological Chemistry 278:47, pages 47209-47216.
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Guang Yu, Hongyu Luo, Yulian Wu & Jiangping Wu. (2003) Ephrin B2 Induces T Cell Costimulation. The Journal of Immunology 171:1, pages 106-114.
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Masaru Nakamoto & Andrew D. Bergemann. (2002) Diverse roles for the Eph family of receptor tyrosine kinases in carcinogenesis. Microscopy Research and Technique 59:1, pages 58-67.
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Xianyong MaTupur HusainHui PengSharon LinOlga MironenkoNoel MaunSteven JohnsonDavid TuckNancy BerlinerDiane S. KrauseArchibald S. Perkins. (2002) Development of a murine hematopoietic progenitor complementary DNA microarray using a subtracted complementary DNA library. Blood 100:3, pages 833-844.
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Juan J. Muñoz, Luis M. Alonso-C.Rosa Sacedón, Tessa Crompton, Angeles Vicente, Eva Jiménez, Alberto Varas & Agustín G. Zapata. (2002) Expression and Function of the Eph A Receptors and Their Ligands Ephrins A in the Rat Thymus. The Journal of Immunology 169:1, pages 177-184.
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Zhengyu WangNobuyuki MiuraAndres BonelliPamela MoleNadia CarlessoDouglas P. OlsonDavid T. Scadden. (2002) Receptor tyrosine kinase, EphB4 (HTK), accelerates differentiation of select human hematopoietic cells. Blood 99:8, pages 2740-2747.
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