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Original Article

Effects of Mutant c-Kit in Early Myeloid Cells

, , &
Pages 451-461 | Received 20 Nov 1998, Published online: 01 Jul 2009

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Read on this site (6)

Maryam Abbaspour Babaei, Behnam Kamalidehghan, Mohammad Saleem, Hasniza Zaman Huri & Fatemeh Ahmadipour. (2016) Receptor tyrosine kinase (c-Kit) inhibitors: a potential therapeutic target in cancer cells. Drug Design, Development and Therapy 10, pages 2443-2459.
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Muneera Al-Hussaini & John F DiPersio. (2014) Small molecule inhibitors in acute myeloid leukemia: from the bench to the clinic. Expert Review of Hematology 7:4, pages 439-464.
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Michel Arock & Peter Valent. (2010) Pathogenesis, classification and treatment of mastocytosis: state of the art in 2010 and future perspectives. Expert Review of Hematology 3:4, pages 497-516.
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Shinsuke Suzuki, Kimiharu Uozumi, Shuichi Hanada, Xiao-Yan Lin, Nobuhito Ohno, Yoshifusa Takatsuka, Syogo Takeuchi, Satsuki Owatari, Taketsugu Takeshita & Terukatsu Arima. (2003) A Novel c-kit Positive Biphenotypic Acute Leukemia Cell Line, TMBL-1, Carrying a p53 Point Mutation. Leukemia & Lymphoma 44:5, pages 849-857.
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Zhi-Qiang Ning, Jin Li & Robert J. Arceci. (2001) Activating Mutations of c-Kit at Codon 816 Confer Drug Resistance in Human Leukemia Cells. Leukemia & Lymphoma 41:5-6, pages 513-522.
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Sarah Moore & Louise A. McDiarmid. (2000) Stem Cell Factor and Chronic Myeloid Leukemia CD34+ Cells. Leukemia & Lymphoma 38:3-4, pages 211-220.
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Articles from other publishers (18)

Angélica Sandoval-Pérez, Beth Apsel Winger & Matthew P. Jacobson. (2022) Assessing the Activation of Tyrosine Kinase KIT through Free Energy Calculations. Journal of Chemical Theory and Computation 18:10, pages 6251-6258.
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Glenn Cruse, Dean D. Metcalfe & Ana Olivera. (2014) Functional Deregulation of KIT. Immunology and Allergy Clinics of North America 34:2, pages 219-237.
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Friedrich Stölzel, Christine Steudel, Uta Oelschlägel, Brigitte Mohr, Sina Koch, Gerhard Ehninger & Christian Thiede. (2010) Mechanisms of resistance against PKC412 in resistant FLT3-ITD positive human acute myeloid leukemia cells. Annals of Hematology 89:7, pages 653-662.
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Irene Ruano, Ricardo Gargini & Marta Izquierdo. (2010) Combination of KIT gene silencing and tocopherol succinate may offer improved therapeutic approaches for human mastocytosis. British Journal of Haematology 148:1, pages 59-68.
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Rob P. Coppes, Annemieke van der Goot & Isabelle M.A. Lombaert. (2009) Stem Cell Therapy to Reduce Radiation-Induced Normal Tissue Damage. Seminars in Radiation Oncology 19:2, pages 112-121.
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Yashoda Sharma, Clinton M. Astle & David E. Harrison. (2007) Heterozygous Kit Mutants with Little or No Apparent Anemia Exhibit Large Defects in Overall Hematopoietic Stem Cell Function. Experimental Hematology 35:2, pages 214.e1-214.e9.
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Tanya JelacicDiana Linnekin. (2005) PKCδ plays opposite roles in growth mediated by wild-type Kit and an oncogenic Kit mutant. Blood 105:5, pages 1923-1929.
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Johan Lennartsson, Tanya Jelacic, Diana Linnekin & R. Shivakrupa. (2009) Normal and Oncogenic Forms of the Receptor Tyrosine Kinase Kit. STEM CELLS 23:1, pages 16-43.
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Rowan Foster, Renate Griffith, Petranel Ferrao & Leonie Ashman. (2004) Molecular basis of the constitutive activity and STI571 resistance of Asp816Val mutant KIT receptor tyrosine kinase. Journal of Molecular Graphics and Modelling 23:2, pages 139-152.
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Ewa WandziochCharlotte E. EdlingRuth H. PalmerLeif CarlssonBengt Hallberg. (2004) Activation of the MAP kinase pathway by c-Kit is PI-3 kinase dependent in hematopoietic progenitor/stem cell lines. Blood 104:1, pages 51-57.
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Vinod A. Pullarkat, Carlos Bueso‐Ramos, Raymond Lai, Steven Kroft, Carla S. Wilson, Sheeja T. Pullarkat, Xiangdong Bu, Maung Thein, M. Lee & Russell K. Brynes. (2003) Systemic mastocytosis with associated clonal hematological non‐mast‐cell lineage disease: Analysis of clinicopathologic features and activating c‐kit mutations . American Journal of Hematology 73:1, pages 12-17.
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Jennifer Reed, Abderrahman Ouban, Frank K. Schickor, Patrick Muraca, Timothy Yeatman & Domenico Coppola. (2002) Immunohistochemical Staining for c-Kit (CD117) Is a Rare Event in Human Colorectal Carcinoma. Clinical Colorectal Cancer 2:2, pages 119-122.
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Naotomo Kambe & Yoshiki Miyachi. (2014) A Possible Mechanism of Mast Cell Proliferation in Mastocytosis. The Journal of Dermatology 29:1, pages 1-9.
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Zhi-Qiang Ning, Jin Li, Myc McGuinness & Robert J Arceci. (2001) STAT3 activation is required for Asp816 mutant c-Kit induced tumorigenicity. Oncogene 20:33, pages 4528-4536.
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Zhi-Qiang NingJin LiRobert J. Arceci. (2001) Signal transducer and activator of transcription 3 activation is required for Asp816 mutant c-Kit–mediated cytokine-independent survival and proliferation in human leukemia cells. Blood 97:11, pages 3559-3567.
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K. Hartmann & B.M. Henz. (2001) Mastocytosis: recent advances in defining the disease. British Journal of Dermatology 144:4, pages 682-695.
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Karin Hartmann & Dean D. Metcalfe. (2000) PEDIATRIC MASTOCYTOSIS. Hematology/Oncology Clinics of North America 14:3, pages 625-640.
Crossref
Leonie K Ashman. (1999) The biology of stem cell factor and its receptor C-kit. The International Journal of Biochemistry & Cell Biology 31:10, pages 1037-1051.
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