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Original Article

An Industrial Perspective on Utilizing Functional Ion Channel Assays for High Throughput Screening

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Pages 269-282 | Published online: 04 Dec 2011

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XiuJun Li & Paul CH Li. (2010) Strategies for the real-time detection of Ca2+ channel events of single cells: recent advances and new possibilities. Expert Review of Clinical Pharmacology 3:3, pages 267-280.
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Jennings Worley. (2003) Guest Editor's Introduction: An Evolution of Electrophysiology. Receptors and Channels 9:1, pages 1-2.
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Guohua Qi, Bo Wang, Ying Zhang, Haijuan Li, Chuanping Li, Weiqing Xu & Yongdong Jin. (2019) Living-Cell Imaging of Mitochondrial Membrane Potential Oscillation and Phenylalanine Metabolism Modulation during Periodic Electrostimulus. Analytical Chemistry 91:15, pages 9571-9579.
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Reka A. Otvos, Kristina B.M. Still, Govert W. Somsen, August B. Smit & Jeroen Kool. (2019) Drug Discovery on Natural Products: From Ion Channels to nAChRs, from Nature to Libraries, from Analytics to Assays. SLAS Discovery 24:3, pages 362-385.
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Michael E. Kort, Irene Drizin, Robert J. Gregg, Marc J. C. Scanio, Lei Shi, Michael F. Gross, Robert N. Atkinson, Matthew S. Johnson, Gregory J. Pacofsky, James B. Thomas, William A. Carroll, Michael J. Krambis, Dong Liu, Char-Chang Shieh, XuFeng Zhang, Gricelda Hernandez, Joseph P. Mikusa, Chengmin Zhong, Shailen Joshi, Prisca Honore, Rosemarie Roeloffs, Kennan C. Marsh, Bernard P. Murray, Jinrong Liu, Stephen Werness, Connie R. Faltynek, Douglas S. Krafte, Michael F. Jarvis, Mark L. Chapman & Brian E. Marron. (2008) Discovery and Biological Evaluation of 5-Aryl-2-furfuramides, Potent and Selective Blockers of the Na v 1.8 Sodium Channel with Efficacy in Models of Neuropathic and Inflammatory Pain . Journal of Medicinal Chemistry 51:3, pages 407-416.
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T. Lehnert, D. M. T. Nguyen, L. Baldi & M. A. M. Gijs. (2006) Glass reflow on 3-dimensional micro-apertures for electrophysiological measurements on-chip. Microfluidics and Nanofluidics 3:1, pages 109-117.
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Chien-Jung Huang, Alec Harootunian, Michael P Maher, Catherine Quan, Christopher D Raj, Ken McCormack, Randal Numann, Paul A Negulescu & Jesús E González. (2006) Characterization of voltage-gated sodium-channel blockers by electrical stimulation and fluorescence detection of membrane potential. Nature Biotechnology 24:4, pages 439-446.
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Jia Xu, Ying Chen & Min Li. (2004) High-throughput technologies for studying potassium channels – progresses and challenges. Drug Discovery Today: TARGETS 3:1, pages 32-38.
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