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Journal of Drug Targeting Volume 18, 2010 - Issue 3
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Research Article

Roles of dextrans on improving lymphatic drainage for liposomal drug delivery system

Linglin Feng
,
Lei ZhangDepartment of Pharmaceutics, School of Pharmacy, Fudan University, Shanghai, P.R. China
,
Min LiuDepartment of Pharmaceutics, School of Pharmacy, Fudan University, Shanghai, P.R. China
,
Zhiqiang YanDepartment of Pharmaceutics, School of Pharmacy, Fudan University, Shanghai, P.R. China
,
Chenyu WangDepartment of Pharmaceutics, School of Pharmacy, Fudan University, Shanghai, P.R. China
,
Bing GuDepartment of Pharmaceutics, School of Pharmacy, Fudan University, Shanghai, P.R. China
,
Yu LiuDepartment of Pharmaceutics, School of Pharmacy, Fudan University, Shanghai, P.R. China
,
Gang WeiDepartment of Pharmaceutics, School of Pharmacy, Fudan University, Shanghai, P.R. China
,
Gaoren ZhongDepartment of Radio Pharmacy, School of Pharmacy, Fudan University, Shanghai, P.R. China
&
Weiyue LuDepartment of Pharmaceutics, School of Pharmacy, Fudan University, Shanghai, P.R. ChinaCorrespondence[email protected]
 show all
Pages 168-178 | Received 27 May 2009, Accepted 08 Sep 2009, Published online: 06 Oct 2009

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Nidhi Singh, Mayank Handa, Vanshikha Singh, Prashant Kesharwani & Rahul Shukla. (2022) Lymphatic targeting for therapeutic application using nanoparticulate systems. Journal of Drug Targeting 30:10, pages 1017-1033.
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Karthik Siram, Gregory Marslin, Chellan Vijaya Raghavan, Krishnamoorthy Balakumar, Habibur Rahman & Gregory Franklin. (2016) A brief perspective on the diverging theories of lymphatic targeting with colloids. International Journal of Nanomedicine 11, pages 2867-2872.
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Indu Singh, Rajan Swami, Wahid Khan & Ramakrishna Sistla. (2014) Lymphatic system: a prospective area for advanced targeting of particulate drug carriers. Expert Opinion on Drug Delivery 11:2, pages 211-229.
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Young-Il Jeong, Do Hyung Kim, Chung-Wook Chung, Jin-Ju Yoo, Kyung Ha Choi, Cy Hyun Kim, Seung Hee Ha & Dae Hwan Kang. (2011) Doxorubicin-incorporated polymeric micelles composed of dextran-b-poly(DL-lactide-co-glycolide) copolymer. International Journal of Nanomedicine 6, pages 1415-1427.
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Articles from other publishers (16)

Yiming Xia, Shunli Fu, Qingping Ma, Yongjun Liu & Na Zhang. (2023) Application of Nano-Delivery Systems in Lymph Nodes for Tumor Immunotherapy. Nano-Micro Letters 15:1.
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Lin Qin, Huilin Zhang, Yang Zhou, Channakeshava Sokke Umeshappa & Huile Gao. (2021) Nanovaccine‐Based Strategies to Overcome Challenges in the Whole Vaccination Cascade for Tumor Immunotherapy. Small 17:28, pages 2006000.
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Sejin Son, Jutaek Nam, Ilia Zenkov, Lukasz J. Ochyl, Yao Xu, Lindsay Scheetz, Jinjun Shi, Omid C. Farokhzad & James J. Moon. (2020) Sugar-Nanocapsules Imprinted with Microbial Molecular Patterns for mRNA Vaccination. Nano Letters 20:3, pages 1499-1509.
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Amira A. Boseila, Hassan M. Rashed, Tamer M. Sakr, Amal Y. Abdel-Reheem & Emad B. Basalious. (2019) Superiority of DEAE-Dx-Stabilized Cationic Bile-Based Vesicles over Conventional Vesicles for Enhanced Hepatic Delivery of Daclatasvir. Molecular Pharmaceutics 16:10, pages 4190-4199.
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Michal Kalina, Andrea Kargerová & Miloslav Pekař. (2019) DEAE-dextran hydrochloride behaviour in aqueous solution—The effect of ionic strength and concentration. Carbohydrate Polymers 220, pages 163-169.
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Brianna Cote, Deepa Rao, Raid G. Alany, Glen S. Kwon & Adam W.G. Alani. (2019) Lymphatic changes in cancer and drug delivery to the lymphatics in solid tumors. Advanced Drug Delivery Reviews 144, pages 16-34.
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Hao Jiang, Qin Wang & Xun Sun. (2017) Lymph node targeting strategies to improve vaccination efficacy. Journal of Controlled Release 267, pages 47-56.
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Gemma M. Ryan, Victoria M. McLeod, Dharmini Mehta, Brian D. Kelly, Pauline C. Stanislawski, David J. Owen, Lisa M. Kaminskas & Christopher J.H. Porter. (2017) Lymphatic transport and lymph node targeting of methotrexate-conjugated PEGylated dendrimers are enhanced by reducing the length of the drug linker or masking interactions with the injection site. Nanomedicine: Nanotechnology, Biology and Medicine 13:8, pages 2485-2494.
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Kritee Pant, Ondřej Sedláček, Robin A. Nadar, Martin Hrubý & Holger Stephan. (2017) Radiolabelled Polymeric Materials for Imaging and Treatment of Cancer: Quo Vadis?. Advanced Healthcare Materials 6:6, pages 1601115.
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Natalie L. Trevaskis, Lisa M. Kaminskas & Christopher J. H. Porter. (2015) From sewer to saviour — targeting the lymphatic system to promote drug exposure and activity. Nature Reviews Drug Discovery 14:11, pages 781-803.
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Premanarayani Menon, Teo Yin Yin & Misni Misran. (2015) Preparation and characterization of liposomes coated with DEAE-Dextran. Colloids and Surfaces A: Physicochemical and Engineering Aspects 481, pages 345-350.
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Gemma M. Ryan, Lisa M. Kaminskas & Christopher J.H. Porter. (2014) Nano-chemotherapeutics: Maximising lymphatic drug exposure to improve the treatment of lymph-metastatic cancers. Journal of Controlled Release 193, pages 241-256.
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Zhiqiang Yan, Fei Wang, Ziyi Wen, Changyou Zhan, Linglin Feng, Yu Liu, Xiaoli Wei, Cao Xie & Weiyue Lu. (2012) LyP-1-conjugated PEGylated liposomes: A carrier system for targeted therapy of lymphatic metastatic tumor. Journal of Controlled Release 157:1, pages 118-125.
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Shuang Cai, Taryn R Bagby & M Laird Forrest. (2011) Development of regional chemotherapies: feasibility, safety and efficacy in clinical use and preclinical studies. Therapeutic Delivery 2:11, pages 1467-1484.
Crossref
Shunhua Ning, Qiyu Huang, Xiaoyi Sun, Chunlei Li, Yi Zhang, Juan Li & You-Nian Liu. (2011) Carboxymethyl dextran-coated liposomes: Toward a robust drug delivery platform. Soft Matter 7:19, pages 9394.
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Ji-Hoon Choi & Yong-Bok Lee. (2010) Nano-sized Drug Carriers and Key Factors for Lymphatic Delivery. Journal of Pharmaceutical Investigation 40:spc, pages 75-82.
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