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Original Article

Preparation of budesonide–dextran conjugates using glutarate spacer as a colon-targeted drug delivery system: in vitro/in vivo evaluation in induced ulcerative colitis

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Pages 140-153 | Received 11 Nov 2009, Accepted 06 Mar 2010, Published online: 30 Apr 2010

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Catherine C. Applegate, Hongping Deng, Brittany L. Kleszynski, Tzu-Wen L. Cross, Christian J. Konopka, L. Wawrzyniec Dobrucki, Erik R. Nelson, Matthew A. Wallig, Andrew M. Smith & Kelly S. Swanson. (2022) Impact of administration route on nanocarrier biodistribution in a murine colitis model. Journal of Experimental Nanoscience 17:1, pages 599-616.
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Manoj Kumar Sarangi, M. E. Bhanoji Rao & Versha Parcha. (2021) Smart polymers for colon targeted drug delivery systems: a review. International Journal of Polymeric Materials and Polymeric Biomaterials 70:16, pages 1130-1166.
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Yan Yan, Pengchong Wang, Ruiying Li, Ying Sun, Rui Zhang, Chuanchuan Huo, Jianfeng Xing & Yalin Dong. (2019) Synthesis of budesonide conjugates and their anti-inflammatory effects: a preliminary study. Drug Design, Development and Therapy 13, pages 681-694.
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Paramjot, Nikhat Mansoor Khan, Himani Kapahi, Sahil Kumar, T. R. Bhardwaj, Saahil Arora & Neeraj Mishra. (2015) Role of polymer–drug conjugates in organ-specific delivery systems. Journal of Drug Targeting 23:5, pages 387-416.
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Jaleh Varshosaz. (2012) Dextran conjugates in drug delivery. Expert Opinion on Drug Delivery 9:5, pages 509-523.
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Jason Silverman & Anthony Otley. (2011) Budesonide in the treatment of inflammatory bowel disease. Expert Review of Clinical Immunology 7:4, pages 419-428.
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Yanzhen Sun, Xiaodong Jing, Xiaoli Ma, Yinglong Feng & Hao Hu. (2020) Versatile Types of Polysaccharide-Based Drug Delivery Systems: From Strategic Design to Cancer Therapy. International Journal of Molecular Sciences 21:23, pages 9159.
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Shiyu Huang & Gangliang Huang. (2019) The dextrans as vehicles for gene and drug delivery. Future Medicinal Chemistry 11:13, pages 1659-1667.
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Reza Baradaran Eftekhari, Niloufar Maghsoudnia, Shabnam Samimi, Ali Zamzami & Farid Abedin Dorkoosh. (2019) Co-Delivery Nanosystems for Cancer Treatment: A Review. Pharmaceutical Nanotechnology 7:2, pages 90-112.
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Filip Kunc, Colin J. Moore, Rachel E. SullyAndrew J. HallVladimir Gubala. (2019) Polycarboxylated Dextran as a Multivalent Linker: Synthesis and Target Recognition of the Antibody–Nanoparticle Bioconjugates in PBS and Serum. Langmuir 35:14, pages 4909-4917.
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Robert C. Waters & Günther Hochhaus. (2019) Characterization of a dextran-budesonide prodrug for inhalation therapy. European Journal of Pharmaceutical Sciences 129, pages 58-67.
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Elahehnaz Parhizkar, Saeid Daneshamouz, Soliman Mohammadi-Samani, Amirhossein Sakhteman, Golnaz Parhizkar, Mahmoud Omidi & Fatemeh Ahmadi. (2017) Synthesis and in vitro assessment of novel water-soluble dextran-docetaxel conjugates as potential pH sensitive system for tumor-targeted delivery . Journal of Applied Polymer Science 134:43, pages 45457.
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Blessing A. Aderibigbe & Hembe E. Mukaya. 2017. Nano- and Microscale Drug Delivery Systems. Nano- and Microscale Drug Delivery Systems 33 48 .
Zhe Wang, Gang Niu & Xiaoyuan Chen. (2013) Polymeric Materials for Theranostic Applications. Pharmaceutical Research 31:6, pages 1358-1376.
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Wahid Khan, Venu Gopala Swami Challa, Robert Langer & Abraham J. Domb. 2014. Focal Controlled Drug Delivery. Focal Controlled Drug Delivery 3 32 .
Raj Kumar Shukla & Akanksha Tiwari. (2012) Carbohydrate polymers: Applications and recent advances in delivering drugs to the colon. Carbohydrate Polymers 88:2, pages 399-416.
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