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Bijun Xia, Xi Liu, Qiong Zhou, Qian Feng, Ye Li, Wei Liu & Zhongqiu Liu. (2013) Disposition of orally administered a promising chemotherapeutic agent flavopiridol in the intestine. Drug Development and Industrial Pharmacy 39:6, pages 845-853.
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I. González-Alvarez, C. Fernández-Teruel, T. M. Garrigues, V. G. Casabo, A. Ruiz-García & M. Bermejo. (2005) Kinetic modelling of passive transport and active efflux of a fluoroquinolone across Caco-2 cells using a compartmental approach in NONMEM. Xenobiotica 35:12, pages 1067-1088.
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C. Fernandez-Teruel, I. Gonzalez-Alvarez, V. G. Casabó, A. Ruiz-Garcia & M. Bermejo. (2005) Kinetic modelling of the intestinal transport of sarafloxacin. Studies in situ in rat and in vitro in Caco-2 cells. Journal of Drug Targeting 13:3, pages 199-212.
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Ming Hu, Lixing Zheng, Jiyue Chen, Lijuan Liu, Yiqi Li, Anne H. Dantzig & Robert E. Stratford. (1995) Peptide Transporter Function and Prolidase Activities in Caco-2 Cells: A Lack of Coordinated Expression. Journal of Drug Targeting 3:4, pages 291-300.
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Articles from other publishers (34)
Xinyu Liu, Shengjie Dong, Yuru Ma, Hu Xu, Hongxia Zhao & Qingzhi Gao. (2019) N-(Sulfamoylbenzoyl)-L-proline Derivatives as Potential Non-β-lactam ESBL Inhibitors: Structure-Based Lead Identification, Medicinal Chemistry and Synergistic Antibacterial Activities. Medicinal Chemistry 15:2, pages 196-206.
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Ji Xia, Yong Fang, Yi Shi, Xinchun Shen, Jian Wu, Minhao Xie, Peng Li, Fei Pei & Qiuhui Hu. (2018) Effect of food matrices on the in vitro bioavailability and oxidative damage in PC12 cells of lead. Food Chemistry 266, pages 397-404.
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Marta González-Alvarez, Carmen Coll, Isabel Gonzalez-Alvarez, Cristina Giménez, Elena Aznar, M. Carmen Martínez-Bisbal, Isabel Lozoya-Agulló, Marival Bermejo, Ramón Martínez-Máñez & Félix Sancenón. (2017) Gated Mesoporous Silica Nanocarriers for a “Two-Step” Targeted System to Colonic Tissue. Molecular Pharmaceutics 14:12, pages 4442-4453.
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Jia Yu, Lijun Zhu, Haihui Zheng, Xia Gong, Huangyu Jiang, Jiamei Chen, Yuhuan Li, Hongming Zheng, Xiaoxiao Qi, Ying Wang, Ming Hu, Linlin Lu & Zhongqiu Liu. (2017)
Sulfotransferases and Breast Cancer Resistance Protein Determine the Disposition of Calycosin
in Vitro
and
in Vivo
. Molecular Pharmaceutics 14:9, pages 2917-2929.
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J. Shi, H. Zheng, J. Yu, L. Zhu, T. Yan, P. Wu, L. Lu, Y. Wang, M. Hu & Z. Liu. (2015) SGLT-1 Transport and Deglycosylation inside Intestinal Cells Are Key Steps in the Absorption and Disposition of Calycosin-7-O- -D-Glucoside in Rats. Drug Metabolism and Disposition 44:3, pages 283-296.
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Guangyi Yang, Song Gao, Rongjin Sun, Taijun Yin & Ming Hu. (2015) Development and validation of an UPLC-MS/MS method for the quantification of columbin in biological matrices: Applications to absorption, metabolism, and pharmacokinetic studies. Journal of Chromatography B 1002, pages 13-18.
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Shufan Ge, Song Gao, Taijun Yin & Ming Hu. (2015) Determination of Pharmacokinetics of Chrysin and Its Conjugates in Wild-Type FVB and Bcrp1 Knockout Mice Using a Validated LC-MS/MS Method. Journal of Agricultural and Food Chemistry 63:11, pages 2902-2910.
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Davinia Oltra-Noguera, Victor Mangas-Sanjuan, Amparo Centelles-Sangüesa, Ignacio Gonzalez-Garcia, Gloria Sanchez-Castaño, Marta Gonzalez-Alvarez, Vicente-German Casabo, Virginia Merino, Isabel Gonzalez-Alvarez & Marival Bermejo. (2015) Variability of permeability estimation from different protocols of subculture and transport experiments in cell monolayers. Journal of Pharmacological and Toxicological Methods 71, pages 21-32.
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Guillermo Rodr?guez-Berna, V?ctor Mangas-Sanju?n, Marta Gonzalez-Alvarez, Isabel Gonzalez-Alvarez, Jos? Luis Garc?a-Gim?nez, Mar?a Jos? D?az Caba?as, Marival Bermejo & Avelino Corma. (2014) A promising camptothecin derivative: Semisynthesis, antitumor activity and intestinal permeability. European Journal of Medicinal Chemistry 83, pages 366-373.
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Song Gao, Taijun Yin, Beibei Xu, Yong Ma & Ming Hu. (2014) Amino acid facilitates absorption of copper in the Caco-2 cell culture model. Life Sciences 109:1, pages 50-56.
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Hai Pham-The, Isabel González-Álvarez, Marival Bermejo, Teresa Garrigues, Huong Le-Thi-Thu & Miguel Ángel Cabrera-Pérez. (2013) The Use of Rule-Based and QSPR Approaches in ADME Profiling: A Case Study on Caco-2 Permeability. Molecular Informatics 32:5-6, pages 459-479.
Crossref
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Ling Ye, Xiaoshan Yang, Zhen Yang, Song Gao, Taijun Yin, Wei Liu, Feng Wang, Ming Hu & Zhongqiu Liu. (2013) The role of efflux transporters on the transport of highly toxic aconitine, mesaconitine, hypaconitine, and their hydrolysates, as determined in cultured Caco-2 and transfected MDCKII cells. Toxicology Letters 216:2-3, pages 86-99.
Crossref
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Zhen Yang, Jing-Rong Wang, Tao Niu, Song Gao, Taijun Yin, Ming You, Zhi-Hong Jiang & Ming Hu. (2012) Inhibition of P-Glycoprotein Leads to Improved Oral Bioavailability of Compound K, an Anticancer Metabolite of Red Ginseng Extract Produced by Gut Microflora. Drug Metabolism and Disposition 40:8, pages 1538-1544.
Crossref
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Ling Ye, Tao Wang, Lan Tang, Wei Liu, Zhen Yang, Juan Zhou, Zhijie Zheng, Zheng Cai, Ming Hu & Zhongqiu Liu. (2011) Poor oral bioavailability of a promising anticancer agent andrographolide is due to extensive metabolism and efflux by P‐glycoprotein. Journal of Pharmaceutical Sciences 100:11, pages 5007-5017.
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Hai Pham The, Isabel González‐Álvarez, Marival Bermejo, Victor Mangas Sanjuan, Inmaculada Centelles, Teresa M. Garrigues & Miguel Ángel Cabrera‐Pérez. (2011) In Silico Prediction of Caco‐2 Cell Permeability by a Classification QSAR Approach. Molecular Informatics 30:4, pages 376-385.
Crossref
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Lan Tang, Ling Ye, Rashim Singh, Baojian Wu, Chang Lv, Jie Zhao, Zhongqiu Liu & Ming Hu. (2010) Use of Glucuronidation Fingerprinting To Describe and Predict Mono- and Dihydroxyflavone Metabolism by Recombinant UGT Isoforms and Human Intestinal and Liver Microsomes. Molecular Pharmaceutics 7:3, pages 664-679.
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Zhen Yang, Song Gao, Taijun Yin, Kaustubh H. Kulkarni, Yang Teng, Ming You & Ming Hu. (2010) Biopharmaceutical and pharmacokinetic characterization of matrine as determined by a sensitive and robust UPLC–MS/MS method. Journal of Pharmaceutical and Biomedical Analysis 51:5, pages 1120-1127.
Crossref
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Zhenting Yuan, Haiyan Xu, Ke Wang, Zhonghua Zhao & Ming Hu. (2009) Determination of osthol and its metabolites in a phase I reaction system and the Caco-2 cell model by HPLC-UV and LC–MS/MS. Journal of Pharmaceutical and Biomedical Analysis 49:5, pages 1226-1232.
Crossref
Crossref
Isabel Gonzalez-Alvarez, Marta Gonzalez-Alvarez, Davinia Oltra-Noguera, Virginia Merino, Nat?lia T?k?si, Judit Ov?di & Marival Bermejo. (2009) Unique pharmacology of KAR-2, a potential anti-cancer agent: Absorption modelling and selective mitotic spindle targeting. European Journal of Pharmaceutical Sciences 36:1, pages 11-19.
Crossref
Crossref
A Lehotzky, N Tőkési, I Gonzalez-Alvarez, V Merino, M Bermejo, F Orosz, P Lau, G.G Kovacs & J Ovádi. (2008) Progress in the development of early diagnosis and a drug with unique pharmacology to improve cancer therapy. Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences 366:1880, pages 3599-3617.
Crossref
Crossref
Stephen W.J. WangYan ChenTiby JosephMing Hu. (2008) Variable Isoflavone Content of Red Clover Products Affects Intestinal Disposition of Biochanin A, Formononetin, Genistein, and Daidzein. The Journal of Alternative and Complementary Medicine 14:3, pages 287-297.
Crossref
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Min-Hyo Ki, Mee-Hwa Choi, Kwang-Bok Ahn, Byoung-Su Kim, Dai Sig Im, Soon-Kil Ahn & Hee-Jong Shin. (2008) The efficacy and safety of clopidogrel resinate as a novel polymeric salt form of clopidogrel. Archives of Pharmacal Research 31:2, pages 250-258.
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Zhong Qiu Liu, Zhi Hong Jiang, Liang Liu & Ming Hu. (2006) Mechanisms Responsible for Poor Oral Bioavailability of Paeoniflorin: Role of Intestinal Disposition and Interactions with Sinomenine. Pharmaceutical Research 23:12, pages 2768-2780.
Crossref
Crossref
Eun Ju Jeong, Xiaobin Jia & Ming Hu. (2005) Disposition of Formononetin via Enteric Recycling: Metabolism and Excretion in Mouse Intestinal Perfusion and Caco-2 Cell Models. Molecular Pharmaceutics 2:4, pages 319-328.
Crossref
Crossref
Eun Ju Jeong, Yong Liu, Huimin Lin & Ming Hu. (2005) SPECIES- AND DISPOSITION MODEL-DEPENDENT METABOLISM OF RALOXIFENE IN GUT AND LIVER: ROLE OF UGT1A10. Drug Metabolism and Disposition 33:6, pages 785-794.
Crossref
Crossref
Jun Chen, Huimin Lin & Ming Hu. (2004) Absorption and metabolism of genistein and its five isoflavone analogs in the human intestinal Caco-2 model. Cancer Chemotherapy and Pharmacology 55:2, pages 159-169.
Crossref
Crossref
Xiaobin Jia, Jun Chen, Huimin Lin & Ming Hu. (2004) Disposition of Flavonoids via Enteric Recycling: Enzyme-Transporter Coupling Affects Metabolism of Biochanin A and Formononetin and Excretion of Their Phase II Conjugates. Journal of Pharmacology and Experimental Therapeutics 310:3, pages 1103-1113.
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Crossref
E. J. Jeong. (2004) Disposition Mechanisms of Raloxifene in the Human Intestinal Caco-2 Model. Journal of Pharmacology and Experimental Therapeutics 310:1, pages 376-385.
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Crossref
Marival Bermejo, Alex Avdeef, Ana Ruiz, Ricardo Nalda, Jeffrey A. Ruell, Oksana Tsinman, Isabel Gonz?lez, Carlos Fern?ndez, Gloria S?nchez, Teresa M. Garrigues & Virginia Merino. (2004) PAMPA?a drug absorption in vitro model. European Journal of Pharmaceutical Sciences 21:4, pages 429-441.
Crossref
Crossref
Ming Hu, June Chen & Huimin Lin. (2003) Metabolism of Flavonoids via Enteric Recycling: Mechanistic Studies of Disposition of Apigenin in the Caco-2 Cell Culture Model. Journal of Pharmacology and Experimental Therapeutics 307:1, pages 314-321.
Crossref
Crossref
Jun Chen, Huimin Lin & Ming Hu. (2003) Metabolism of Flavonoids via Enteric Recycling: Role of Intestinal Disposition. Journal of Pharmacology and Experimental Therapeutics 304:3, pages 1228-1235.
Crossref
Crossref
Ana Ruiz-GarcÍa, Huimin Lin, JosÉ M. PlÁ-Delfina & Ming Hu. (2002) Kinetic Characterization of Secretory Transport of a New Ciprofloxacin Derivative (CNV97100) across Caco-2 Cell Monolayers**This work has been submitted for the partial fulfillment of the requirement for a Ph.D. Degree in Pharmaceutics at the University of Valencia, Valencia, Spain. Journal of Pharmaceutical Sciences 91:12, pages 2511-2519.
Crossref
Crossref
Yan Liu & Ming Hu. (2002) Absorption and Metabolism of Flavonoids in the Caco-2 Cell Culture Model and a Perused Rat Intestinal Model. Drug Metabolism and Disposition 30:4, pages 370-377.
Crossref
Crossref
Michael T. Kuhfeld & Robert E. StratfordJr.Jr.. (1996) In vitro measurement of drug transport using a new diffusion chamber compatible with Millicell? culture supports: Performance with caco-2 monolayers. International Journal of Pharmaceutics 133:1-2, pages 47-58.
Crossref
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