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Journal of Drug Targeting Volume 3, 1996 - Issue 5
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Research Article

Gamma Scintigraphy of the Biodistribution of 123I-Labelled N-(2-Hydroxypropyl)methacrylamide Copolymer-Doxorubicin Conjugates in Mice with Transplanted Melanoma and Mammary Carcinoma

Malcolm V. Pimm Cancer Research Laboratories, University of Nottingham, Nottingham, NC7 2RD, UK
,
Alan C. Perkins Department of Medical Physics, University Hospital, Nottingham, NC7 2UH, UK
,
Jiri Strohalm Institute of Macromolecular Chemistry, Academy of Sciences of the Czech Republic, 16206, Prague 6, Czech Republic
,
Karel Ulbrich Institute of Macromolecular Chemistry, Academy of Sciences of the Czech Republic, 16206, Prague 6, Czech Republic
&
Ruth Duncan Cancer Research Campaign's Polymer Controlled Drug Delivery Group, Keele University, Keele, Staffordshire, ST5 5BC, UK; Centre for Polymer Therapeutics, The School of Pharmacy, 29/39 Brunswick Square, London, WC1N 1AX, UK
Pages 375-383 | Received 30 Jun 1995, Published online: 28 Sep 2008

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Alan C. Perkins. (1998) Polymer Diagnostics: The Next Generation of Image Contrast Agents. Journal of Drug Targeting 6:2, pages 79-84.
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J W Hopewell, R Duncan, D Wilding & K Chakrabarti. (2016) Preclinical evaluation of the cardiotoxicity of PK2: A novel HPMA copolymer–doxorubicin–galactosamine conjugate antitumour agent. Human & Experimental Toxicology 20:9, pages 461-470.
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Ruth Duncan. (1999) Polymer conjugates for tumour targeting and intracytoplasmic delivery. The EPR effect as a common gateway?. Pharmaceutical Science & Technology Today 2:11, pages 441-449.
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Jane-Guo Shiah, Yongen Sun, C.Matthew Peterson & Jindřich Kopeček. (1999) Biodistribution of free and N -(2-hydroxypropyl)methacrylamide copolymer-bound mesochlorin e 6 and adriamycin in nude mice bearing human ovarian carcinoma OVCAR-3 xenografts. Journal of Controlled Release 61:1-2, pages 145-157.
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Alan C. Perkins, Malcolm Frier, Malcolm V. Pimm & Ferenc Hudecz. (1998) 99mTc-branched-chain-polypeptide (BCP): a potential synthetic radiopharmaceutical. Journal of Labelled Compounds and Radiopharmaceuticals 41:7, pages 631-638.
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Ijeoma F Uchegbu & Ruth Duncan. (1997) Niosomes containing N-(2-hydroxypropyl)methacrylamide copolymer-doxorubicin (PK1): effect of method of preparation and choice of surfactant on niosome characteristics and a preliminary study of body distribution. International Journal of Pharmaceutics 155:1, pages 7-17.
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Elisabetta Gianasi, Fausto Cociancich, Ijeoma F. Uchegbu, Alexander T. Florence & Ruth Duncan. (1997) Pharmaceutical and biological characterisation of a doxorubicin-polymer conjugate (PK1) entrapped in sorbitan monostearate Span 60 niosomes. International Journal of Pharmaceutics 148:2, pages 139-148.
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