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Journal of Drug Targeting Volume 4, 1996 - Issue 2
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Research Article

Osteotropic drug delivery system (ODDS) based on bisphosphonic prodrug. III: pharmacokinetics and targeting characteristics of osteotropic carboxyfluorescein

Jiro Fujisaki Pharmaceutical and Pharmacokinetic Research Laboratories, Fujisaiva Pharmaceutical Company Ltd., 1-6, Z-chome, Kashima
,
Yuji Tokunaga Pharmaceutical and Pharmacokinetic Research Laboratories, Fujisaiva Pharmaceutical Company Ltd., 1-6, Z-chome, Kashima
,
Taiji Sawamoto Pharmaceutical and Pharmacokinetic Research Laboratories, Fujisaiva Pharmaceutical Company Ltd., 1-6, Z-chome, Kashima
,
Toshiya Takahashi Pharmaceutical and Pharmacokinetic Research Laboratories, Fujisaiva Pharmaceutical Company Ltd., 1-6, Z-chome, Kashima
,
Sumihisa Kimura Pharmaceutical and Pharmacokinetic Research Laboratories, Fujisaiva Pharmaceutical Company Ltd., 1-6, Z-chome, Kashima
,
Fumio Shimojo Pharmaceutical and Pharmacokinetic Research Laboratories, Fujisaiva Pharmaceutical Company Ltd., 1-6, Z-chome, Kashima
&
Takehisa Hata Pharmaceutical and Pharmacokinetic Research Laboratories, Fujisaiva Pharmaceutical Company Ltd., 1-6, Z-chome, Kashima
 show all
Pages 117-123 | Received 28 Sep 1995, Accepted 05 Apr 1995, Published online: 20 Oct 2008

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Shuyun Liu, Wenzhu Bi, Xu Li, Xiaolan Chen, Lingbo Qu & Yufen Zhao. (2015) A Practical Method to Synthesize 1,2,3-Triazole-Amino-Bisphosphonate Derivatives. Phosphorus, Sulfur, and Silicon and the Related Elements 190:11, pages 1735-1742.
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Mohammad Fazil, Sanjula Baboota, Jasjeet K. Sahni, Ameeduzzafar & Javed Ali. (2015) Bisphosphonates: therapeutics potential and recent advances in drug delivery. Drug Delivery 22:1, pages 1-9.
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Jiro Fujisaki, Yuji Tokunaga, Toshiya Takahashi, Fumio Shimojo, Sumihisa Kimura & Takehisa Hata. (1998) Osteotropic Drug Delivery System (ODDS) Based on Bisphosphonic Prodrug. IV Effects of Osteotropic Estradiol on Bone Mineral Density and Uterine Weight in Ovariectomized Rats. Journal of Drug Targeting 5:2, pages 129-138.
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Articles from other publishers (13)

Konstantinos E. Papathanasiou, Maria Vassaki, Argyro Spinthaki, Argyri Moschona & Konstantinos D. Demadis. 2018. Polymer Gels. Polymer Gels 127 140 .
Satyawan B Jadhav & Girish Kumar Jain. (2006) Statins and osteoporosis: new role for old drugs. Journal of Pharmacy and Pharmacology 58:1, pages 3-18.
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Kelly S.E. Tanaka, Evelyne Dietrich, Stéphane Ciblat, Claude Métayer, Francis F. Arhin, Ingrid Sarmiento, Gregory Moeck, Thomas R. ParrJr.Jr. & Adel Rafai Far. (2010) Synthesis and in vitro evaluation of bisphosphonated glycopeptide prodrugs for the treatment of osteomyelitis. Bioorganic & Medicinal Chemistry Letters 20:4, pages 1355-1359.
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Ranga Reddy, Evelyne Dietrich, Yanick Lafontaine, Tom J. Houghton, Odette Belanger, Anik Dubois, Francis F. Arhin, Ingrid Sarmiento, Ibtihal Fadhil, Karine Laquerre, Valerie Ostiguy, Dario Lehoux, Gregory Moeck, Thomas R. ParrJr.Jr. & Adel Rafai Far. (2008) Bisphosphonated Benzoxazinorifamycin Prodrugs for the Prevention and Treatment of Osteomyelitis. ChemMedChem 3:12, pages 1863-1868.
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Tom J. Houghton, Kelly S. E. Tanaka, Ting Kang, Evelyne Dietrich, Yanick Lafontaine, Daniel Delorme, Sandra S. Ferreira, Frederic Viens, Francis F. Arhin, Ingrid Sarmiento, Dario Lehoux, Ibtihal Fadhil, Karine Laquerre, Jing Liu, Valérie Ostiguy, Hugo Poirier, Gregory Moeck, Thomas R. ParrJr.Jr. & Adel Rafai Far. (2008) Linking Bisphosphonates to the Free Amino Groups in Fluoroquinolones: Preparation of Osteotropic Prodrugs for the Prevention of Osteomyelitis. Journal of Medicinal Chemistry 51:21, pages 6955-6969.
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Kelly S.E. Tanaka, Tom J. Houghton, Ting Kang, Evelyne Dietrich, Daniel Delorme, Sandra S. Ferreira, Laurence Caron, Frederic Viens, Francis F. Arhin, Ingrid Sarmiento, Dario Lehoux, Ibtihal Fadhil, Karine Laquerre, Jing Liu, Valérie Ostiguy, Hugo Poirier, Gregory Moeck, Thomas R. ParrJr.Jr. & Adel Rafai Far. (2008) Bisphosphonated fluoroquinolone esters as osteotropic prodrugs for the prevention of osteomyelitis. Bioorganic & Medicinal Chemistry 16:20, pages 9217-9229.
Crossref
Hideki Hirabayashi & Jiro Fujisaki. (2003) Bone-Specific Drug Delivery Systems. Clinical Pharmacokinetics 42:15, pages 1319-1330.
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David Stepensky, Lilach Kleinberg & Amnon Hoffman. (2003) Bone as an Effect Compartment. Clinical Pharmacokinetics 42:10, pages 863-881.
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Hideki Hirabayashi, Taiji Sawamoto, Jiro Fujisaki, Yuji Tokunaga, Sumihisa Kimura & Takehisa Hata. (2002) Dose‐dependent pharmacokinetics and disposition of bisphosphonic prodrug of diclofenac based on osteotropic drug delivery system (ODDS). Biopharmaceutics & Drug Disposition 23:8, pages 307-315.
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Atif Zaheer, Robert E. Lenkinski, Ashfaq Mahmood, Alun G. Jones, Lewis C. Cantley & John V. Frangioni. (2001) In vivo near-infrared fluorescence imaging of osteoblastic activity. Nature Biotechnology 19:12, pages 1148-1154.
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Hideki Hirabayashi, Toshiya Takahashi, Jiro Fujisaki, Taro Masunaga, Sachio Sato, Jun Hiroi, Yuji Tokunaga, Sumihisa Kimura & Takehisa Hata. (2001) Bone-specific delivery and sustained release of diclofenac, a non-steroidal anti-inflammatory drug, via bisphosphonic prodrug based on the Osteotropic Drug Delivery System (ODDS). Journal of Controlled Release 70:1-2, pages 183-191.
Crossref
Aviva Ezra & Gershon Golomb. (2000) Administration routes and delivery systems of bisphosphonates for the treatment of bone resorption. Advanced Drug Delivery Reviews 42:3, pages 175-195.
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Shohei Kasugai, Ryuichi Fujisawa, Yoshihiro Waki, Ken‐Ichi Miyamoto & Keiichi Ohya. (2010) Selective Drug Delivery System to Bone: Small Peptide (Asp) 6 Conjugation . Journal of Bone and Mineral Research 15:5, pages 936-943.
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