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Journal of Drug Targeting Volume 6, 1998 - Issue 1
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Original Article

Production and Characterization of Fusion Proteins Containing Transferrin and Nerve Growth Factor

E. Park Alkermes, Inc., 64 Sidney Street, Cambridge, MA, 02139, USA; Massachusetts General Hospital, Boston, MA, 02114, USA
,
R. M. Starzyk Alkermes, Inc., 64 Sidney Street, Cambridge, MA, 02139, USA; Genetics Institute, Cambridge, MA, 02140, USA
,
J. P. McGrath Alkermes, Inc., 64 Sidney Street, Cambridge, MA, 02139, USA
,
T. Lee Alkermes, Inc., 64 Sidney Street, Cambridge, MA, 02139, USA; Department of Biology, MIT, Cambridge, MA, 02139, USA
,
J. George Alkermes, Inc., 64 Sidney Street, Cambridge, MA, 02139, USA; BASF Bioresearch Corporation, Worcester, MA, 01605, USA
,
A. J. Schutz Alkermes, Inc., 64 Sidney Street, Cambridge, MA, 02139, USA; Genzyme Corporation, Cambridge, MA, 02139, USA
,
P. Lynch Alkermes, Inc., 64 Sidney Street, Cambridge, MA, 02139, USA; PerSeptive Biosystems, Framingham, MA, 01701, USA
&
S. D. Putney Alkermes, Inc., 64 Sidney Street, Cambridge, MA, 02139, USACorrespondence[email protected]
 show all
Pages 53-64 | Received 01 Aug 1997, Accepted 22 Oct 1997, Published online: 26 Jun 2009

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Dennis Keefe, Chuenlei Parng, Dianna Lundberg, Satyajit Ray, Jennifer Martineau-Bosco, Charan Leng, Socrates Tzartos, Jan Powell, Michael Concino, Michael Heartlein, Justin Lamsa & Serene Josiah. (2010) In vitro characterization of an acetylcholine receptor–transferrin fusion protein for the treatment of myasthenia gravis. Autoimmunity 43:8, pages 628-639.
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Chien-Hsing Chang, Pankaj Gupta & David M Goldenberg. (2009) Advances and challenges in developing cytokine fusion proteins as improved therapeutics. Expert Opinion on Drug Discovery 4:2, pages 181-194.
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Jia Huang, C. Wong Po Foo & David L. Kaplan. (2007) Biosynthesis and Applications of Silk‐like and Collagen‐like Proteins. Polymer Reviews 47:1, pages 29-62.
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Articles from other publishers (11)

Abul Bashar Mohammad Giasuddin & David W. Britt. (2019) Microwave Assisted Sol-Gel Synthesis of Silica-Spider Silk Composites. Molecules 24:14, pages 2521.
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Tamina Johnson & Piyush Koria. (2016) Expression and Purification of Neurotrophin-Elastin-Like Peptide Fusion Proteins for Neural Regeneration. BioDrugs 30:2, pages 117-127.
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Stefan R. Schmidt. 2013. Fusion Protein Technologies for Biopharmaceuticals. Fusion Protein Technologies for Biopharmaceuticals 91 106 .
Stefan R. Schmidt. 2013. Fusion Protein Technologies for Biopharmaceuticals. Fusion Protein Technologies for Biopharmaceuticals 383 395 .
Kai Wei, Byoung-Suhk Kim, Koji Abe, Guo-Qiang Chen & Ick-Soo Kim. (2012) Fabrication and Fibroblast Attachment Property of Regenerated Silk Fibroin/Tetramethoxysilane Nanofibrous Biocomposites. Advanced Engineering Materials 14:5, pages B258-B265.
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Nurmamet Amet, Hsin-Fang Lee & Wei-Chiang Shen. (2008) Insertion of the Designed Helical Linker Led to Increased Expression of Tf-Based Fusion Proteins. Pharmaceutical Research 26:3, pages 523-528.
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Cheryl Wong Po FooSiddharth V. Patwardhan, David J. Belton, Brandon KitchelDaphne AnastasiadesJia HuangRajesh R. Naik, Carole C. Perry & David L. Kaplan. (2006) Novel nanocomposites from spider silk–silica fusion (chimeric) proteins. Proceedings of the National Academy of Sciences 103:25, pages 9428-9433.
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Eain M Cornford & Marcia E Cornford. (2002) New systems for delivery of drugs to the brain in neurological disease. The Lancet Neurology 1:5, pages 306-315.
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Hongyan Li & Zhong Ming Qian. (2002) Transferrin/transferrin receptor‐mediated drug delivery. Medicinal Research Reviews 22:3, pages 225-250.
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S.P Vyas & V Sihorkar. (2000) Endogenous carriers and ligands in non-immunogenic site-specific drug delivery. Advanced Drug Delivery Reviews 43:2-3, pages 101-164.
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Chris S. Russell & Lorne A. Clarke. (2001) Recombinant proteins for genetic disease. Clinical Genetics 55:6, pages 389-394.
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