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Journal of Drug Targeting Volume 7, 1999 - Issue 5
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Original Article

Studies on Uptake, Sub-Cellular Trafficking and Efflux of Antisense Oligodeoxynucleotides in Glioma Cells using Self-Assembling Cationic Lipoplexes as Delivery Systems

Aminul Islam Department of Pharmaceutical and Biological Sciences, Pharmaceutical Sciences Institute, Aston University, Aston Triangle, Birmingham, B4 7ET, UKCorrespondence[email protected]
,
Sheila L. Handley Department of Pharmaceutical and Biological Sciences, Pharmaceutical Sciences Institute, Aston University, Aston Triangle, Birmingham, B4 7ET, UK
,
Kevin S.J. Thompson Knoll Pharmaceuticals, CNS Biology, R3 Pennyfoot Street, Nottingham, NG1 IGF, UK
&
Saghir Akhtar Department of Pharmaceutical and Biological Sciences, Pharmaceutical Sciences Institute, Aston University, Aston Triangle, Birmingham, B4 7ET, UK
Pages 373-382 | Received 14 Jan 1999, Accepted 21 Jul 1999, Published online: 26 Jun 2009

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Nicholas C Nicolaides, Philip M Sass & Luigi Grasso. (2010) Advances in targeted therapeutic agents. Expert Opinion on Drug Discovery 5:11, pages 1123-1140.
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Vladimir Khazak, Igor Astsaturov, Ilya G Serebriiskii & Erica A Golemis. (2007) Selective Raf inhibition in cancer therapy. Expert Opinion on Therapeutic Targets 11:12, pages 1587-1609.
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Victor M. Meidan, Judith Glezer, Sharona Salomon, Yechezkel Sidi, Yechezkel Barenholz, Jack S. Cohen & Gila Lilling. (2006) Specific Lipoplex-Mediated Antisense Against Bcl-2 in Breast Cancer Cells: A Comparison between Different Formulations. Journal of Liposome Research 16:1, pages 27-43.
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Z Zhang & HJ Schluesener. (2005) Pigpen is a cellular binding protein of therapeutic oligonucleotides. Cytotherapy 7:2, pages 186-194.
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Ian R. Gilmore, Stephen P. Fox, Andrew J. Hollins, Muhammad Sohail & Saghir Akhtar. (2004) The Design and Exogenous Delivery of siRNA for Post-transcriptional Gene Silencing. Journal of Drug Targeting 12:6, pages 315-340.
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Liam Good. (2002) Antisense antibacterials. Expert Opinion on Therapeutic Patents 12:8, pages 1173-1179.
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Articles from other publishers (12)

Epaminondas Doxakis. (2020) Therapeutic antisense oligonucleotides for movement disorders. Medicinal Research Reviews 41:5, pages 2656-2688.
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Sara Karaki, Clément Paris & Palma Rocchi. 2019. Antisense Therapy. Antisense Therapy.
Alexei A. Bogdanov, Valeriy Metelev, Toloo Taghian, Ilya D. Solovyev, Anand T. N. Kumar, Surong Zhang & Alexander Savitsky. (2019) Near-infrared oligonucleotide duplex sensors for imaging rapidly activated transcription factors in vitro and in situ. Near-infrared oligonucleotide duplex sensors for imaging rapidly activated transcription factors in vitro and in situ.
Shengqi Wang, Dandan Lu, Qingqing Wang, Haifeng Song, Chan Gao, Caihong Liu & Ying Wang. 2011. Medicinal Chemistry of Nucleic Acids. Medicinal Chemistry of Nucleic Acids 349 389 .
David A. Dean & Kerimi E. Gokay. 2005. Nuclear Import and Export in Plants and Animals. Nuclear Import and Export in Plants and Animals 187 205 .
Aminul Islam, Kevin S.J. Thompson, Saghir Akhtar & Sheila L. Handley. (2004) Increased 5-HT2A receptor expression and function following central glucocorticoid receptor knockdown in vivo. European Journal of Pharmacology 502:3, pages 213-220.
Crossref
Stephen Fox, Saghir Akhtar & Andrew Hollins. 2004. Gene Silencing by RNA Interference. Gene Silencing by RNA Interference.
Charles M. RothSumati Sundaram. (2004) Engineering Synthetic Vectors for Improved DNA Delivery: Insights from Intracellular Pathways. Annual Review of Biomedical Engineering 6:1, pages 397-426.
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Norbert Dinauer, Dirk Lochmann, Ilhan Demirhan, Abdellatif Bouazzaoui, Andreas Zimmer, Angelika Chandra, Jörg Kreuter & Hagen von Briesen. (2004) Intracellular tracking of protamine/antisense oligonucleotide nanoparticles and their inhibitory effect on HIV-1 transactivation. Journal of Controlled Release 96:3, pages 497-507.
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Amelia K Petch, Muhammad Sohail, Marcus D Hughes, Ibrahim Benter, John Darling, Edwin M Southern & Saghir Akhtar. (2003) Messenger RNA expression profiling of genes involved in epidermal growth factor receptor signalling in human cancer cells treated with scanning array-designed antisense oligonucleotides. Biochemical Pharmacology 66:5, pages 819-830.
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Marcus D Hughes, Majad Hussain, Qamar Nawaz, Pakeeza Sayyed & Saghir Akhtar. (2001) The cellular delivery of antisense oligonucleotides and ribozymes. Drug Discovery Today 6:6, pages 303-315.
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Saghir Akhtar, Marcus D. Hughes, Alim Khan, Mike Bibby, Majad Hussain, Qamar Nawaz, John Double & Pakeeza Sayyed. (2000) The delivery of antisense therapeutics. Advanced Drug Delivery Reviews 44:1, pages 3-21.
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