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Journal of Drug Targeting Volume 19, 2011 - Issue 6
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Research Article

Development of a novel polyethylene glycol-corticosteroid-conjugate with an acid-cleavable linker

Dorothee FunkNational Center for Tumor Diseases (NCT) and German Cancer Research Center (DKFZ), Division of Preventive Oncology, Heidelberg, Germany
,
Hans-Hermann SchrenkGerman Cancer Research Center (DKFZ), Division of Functional Proteome Analysis, Heidelberg, Germany
&
Eva FreiNational Center for Tumor Diseases (NCT) and German Cancer Research Center (DKFZ), Division of Preventive Oncology, Heidelberg, GermanyCorrespondence[email protected]
Pages 434-445 | Received 18 Mar 2010, Accepted 11 Jun 2010, Published online: 02 Aug 2010

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Cody P Coyne & Lakshmi Narayanan. (2016) Dexamethasone-(C21-phosphoramide)-[anti-EGFR]: molecular design, synthetic organic chemistry reactions, and antineoplastic cytotoxic potency against pulmonary adenocarcinoma (A549). Drug Design, Development and Therapy 10, pages 2575-2597.
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Articles from other publishers (14)

Mujeeb Ur-Rehman, Franceline Reynaud, Sinda Lepetre, Sonia Abreu, Pierre Chaminade, Elias Fattal & Nicolas Tsapis. (2023) Modulation of release and pharmacokinetics from nanoscale lipid prodrugs of dexamethasone with variable linkage chemistry. Journal of Controlled Release 360, pages 293-303.
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Barbara Tessier, Nicolas Tsapis, Elias Fattal & Laurence Moine. (2023) Emerging nanoparticle platforms to improve the administration of glucocorticoids. Journal of Controlled Release 358, pages 273-292.
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Hong Guo, Jibin Guan, Xian Wu, Yushuang Wei, Jiaqi Zhao, Yan Zhou, Faqian Li & Hong-Bo Pang. (2023) Peptide-guided delivery improves the therapeutic efficacy and safety of glucocorticoid drugs for treating acute lung injury. Molecular Therapy 31:3, pages 875-889.
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Shuai Jiang, Domenik Prozeller, Jorge Pereira, Johanna Simon, Shen Han, Sebastian Wirsching, Michael Fichter, Milagro Mottola, Ingo Lieberwirth, Svenja Morsbach, Volker Mailänder, Stephan Gehring, Daniel Crespy & Katharina Landfester. (2020) Controlling protein interactions in blood for effective liver immunosuppressive therapy by silica nanocapsules. Nanoscale 12:4, pages 2626-2637.
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Cody P. Coyne & Lakshmi Narayanan. (2019) Carnosic Acid, Tangeretin, and Ginkgolide-B Anti-neoplastic Cytotoxicity in Dual Combination with Dexamethasone-[anti-EGFR] in Pulmonary Adenocarcinoma (A549). Anti-Cancer Agents in Medicinal Chemistry 19:6, pages 802-819.
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Cody P. Coyne & Lakshmi Narayanan. (2018) Anti-neoplastic cytotoxicity by complementary simultaneous selective “targeted” delivery for pulmonary adenocarcinoma: fludarabine-(5′-phosphoramidate)-[anti-IGF-1R] in dual-combination with dexamethasone-(C21-phosphoramidate)-[anti-EGFR]. Journal of Pharmaceutical Investigation 49:1, pages 173-193.
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Thanapha Numpilai, Thongthai Witoon, Metta Chareonpanich & Jumras Limtrakul. (2017) Impact of physicochemical properties of porous silica materials conjugated with dexamethasone via pH-responsive hydrazone bond on drug loading and release behavior. Applied Surface Science 396, pages 504-514.
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Ilknur Yildirim, Sarah Crotty, Claas H. Loh, Grit Festag, Christine Weber, Pier-Francesco Caponi, Michael Gottschaldt, Matthias Westerhausen & Ulrich S. Schubert. (2016) End-functionalized polylactides using a calcium-based precatalyst: Synthesis and insights by mass spectrometry. Journal of Polymer Science Part A: Polymer Chemistry 54:3, pages 437-448.
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Richard d'Arcy & Nicola Tirelli. (2014) Fishing for fire: strategies for biological targeting and criteria for material design in anti-inflammatory therapies. Polymers for Advanced Technologies 25:5, pages 478-498.
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Rajesh A. Shenoi, Fang Gao, Muhammad Imran Ul-Haq & Jayachandran N. Kizhakkedathu. 2014. Chemistry of Bioconjugates. Chemistry of Bioconjugates 77 103 .
Wenyu Li, Peng Zhang, Kun Zheng, Qiaoling Hu & Youxiang Wang. (2013) Redox-triggered intracellular dePEGylation based on diselenide-linked polycations for DNA delivery. Journal of Materials Chemistry B 1:46, pages 6418.
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Fumiyoshi Yamashita & Mitsuru Hashida. (2013) Pharmacokinetic considerations for targeted drug delivery. Advanced Drug Delivery Reviews 65:1, pages 139-147.
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Fang Yuan, Ling-dong Quan, Liao Cui, Steven R. Goldring & Dong Wang. (2012) Development of macromolecular prodrug for rheumatoid arthritis. Advanced Drug Delivery Reviews 64:12, pages 1205-1219.
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Bart J. Crielaard, Twan Lammers, Raymond M. Schiffelers & Gert Storm. (2012) Drug targeting systems for inflammatory disease: One for all, all for one. Journal of Controlled Release 161:2, pages 225-234.
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