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Original Article

Diffusion loading and drug delivery characteristics of alginate gel microparticles produced by a novel impinging aerosols method

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Pages 831-841 | Received 21 Jul 2010, Accepted 17 Sep 2010, Published online: 19 Oct 2010

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Su Hung Ching, Nidhi Bansal & Bhesh Bhandari. (2017) Alginate gel particles–A review of production techniques and physical properties. Critical Reviews in Food Science and Nutrition 57:6, pages 1133-1152.
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Dewi Melani Hariyadi, Yiwei Wang, Sharon Chien-Yu Lin, Thor Bostrom, Bhesh Bhandari & Allan G. A. Coombes. (2012) Novel alginate gel microspheres produced by impinging aerosols for oral delivery of proteins. Journal of Microencapsulation 29:3, pages 250-261.
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Dewi Melani Hariyadi, Thor Bostrom, Bhesh Bhandari & Allan G. A. Coombes. (2012) A novel impinging aerosols method for production of propranolol hydrochloride-loaded alginate gel microspheres for oral delivery. Journal of Microencapsulation 29:1, pages 63-71.
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Mostafa Fytory, Amira Mansour, Waleed M. A. El Rouby, Ahmed A. Farghali, Xiaorong Zhang, Frank Bier, Mahmoud Abdel-Hafiez & Ibrahim M. El-Sherbiny. (2023) Core–Shell Nanostructured Drug Delivery Platform Based on Biocompatible Metal–Organic Framework-Ligated Polyethyleneimine for Targeted Hepatocellular Carcinoma Therapy. ACS Omega 8:23, pages 20779-20791.
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Beatriz Arauzo, Álvaro González-Garcinuño, Antonio Tabernero, Maria Pilar Lobera, Jesus Santamaria & Eva María Martín del Valle. (2021) Tuning Alginate Microparticle Size via Atomization of Non-Newtonian Fluids. Materials 14:24, pages 7601.
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Kelsey Willson, Anthony Atala & James J. Yoo. (2021) Bioprinting Au Natural: The Biologics of Bioinks. Biomolecules 11:11, pages 1593.
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Yiik Siang Hii, Ming Chiat Law & Yen San Chan. (2021) Experimental and numerical study of the impinging aerosols method for the micro-encapsulation of phosphate solubilising microorganisms (PSMs). Biochemical Engineering Journal 174, pages 108118.
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A. Sosnik. 2021. Soft Matter for Biomedical Applications. Soft Matter for Biomedical Applications 155 179 .
F. Smaniotto, I. Zafeiri, V. Prosapio & F. Spyropoulos. (2021) Understanding the encapsulation and release of small molecular weight model actives from alginate fluid gels. Food Structure 27, pages 100179.
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Dewi Melani Hariyadi & Nazrul Islam. (2020) Current Status of Alginate in Drug Delivery. Advances in Pharmacological and Pharmaceutical Sciences 2020, pages 1-16.
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Boon-Beng Lee, Bhesh R. Bhandari, Su Hung Ching & Tony Howes. (2019) Improving Hydrophilic Barriers of Encapsulated Compounds in Ca-Alginate Microgel Particles through a New Ionotropic Gelation Method for Double Emulsion Droplets. Food Biophysics 14:4, pages 365-382.
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Dewi Melani HariyadiNoorma RositaFitria Nugrahaeni. (2018) Formulation, Characteristic Evaluation, Stress Test and Effectiveness Study of Matrix Metalloproteinase-1 (MMP-1) Expression of Glutathione Loaded Alginate Microspheres and Gel. Pharmaceutical Sciences 24:4, pages 304-312.
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Yassmin O. Samak, Magda El Massik & Allan G.A. Coombes. (2017) A Comparison of Aerosolization and Homogenization Techniques for Production of Alginate Microparticles for Delivery of Corticosteroids to the Colon. Journal of Pharmaceutical Sciences 106:1, pages 208-216.
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Ramendra K. Pal, Nicholas E. Kurland, Chenyang Jiang, Subhas C. Kundu, Ning Zhang & Vamsi K. Yadavalli. (2016) Fabrication of precise shape-defined particles of silk proteins using photolithography. European Polymer Journal 85, pages 421-430.
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Boon-Beng Lee, Bhesh R. Bhandari & Tony Howes. (2016) Air Extrusion System for Ionotropic Alginate Microgel Particle Formation: A Review. Chemical Engineering & Technology 39:12, pages 2355-2369.
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Arundhati Maitra, Sadé Bates, Monisha Shaik, Dimitrios Evangelopoulos, Ibrahim Abubakar, Timothy D. McHugh, Marc Lipman & Sanjib Bhakta. (2016) Repurposing drugs for treatment of tuberculosis: a role for non-steroidal anti-inflammatory drugs. British Medical Bulletin 118:1, pages 138-148.
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Jun-Yee Leong, Weng-Hoong Lam, Kiang-Wei Ho, Wan-Ping Voo, Micky Fu-Xiang Lee, Hui-Peng Lim, Swee-Lu Lim, Beng-Ti Tey, Denis Poncelet & Eng-Seng Chan. (2016) Advances in fabricating spherical alginate hydrogels with controlled particle designs by ionotropic gelation as encapsulation systems. Particuology 24, pages 44-60.
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Fuguang Jiang, Chih-Ko Yeh, Jianchuan Wen & Yuyu Sun. (2015) N -trimethylchitosan/Alginate Layer-by-Layer Self Assembly Coatings Act as “Fungal Repellents” to Prevent Biofilm Formation on Healthcare Materials . Advanced Healthcare Materials 4:3, pages 469-475.
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Alejandro Sosnik. (2014) Alginate Particles as Platform for Drug Delivery by the Oral Route: State-of-the-Art. ISRN Pharmaceutics 2014, pages 1-17.
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Paul Zarogoulidis, Ioannis Kioumis, Christos Ritzoulis, Dimitris Petridis, Kaid Darwiche, Konstantinos Porpodis, Dionysis Spyratos, Scott Parrish, Robert Browning, Qiang Li, J. Francis Turner, Lutz Freitag & Konstantinos Zarogoulidis. (2013) New insights in the production of aerosol antibiotics. Evaluation of the optimal aerosol production system for ampicillin-sulbactam, meropenem, ceftazidime, cefepime and piperacillin-tazobactam. International Journal of Pharmaceutics 455:1-2, pages 182-188.
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Paul Zarogoulidis, Dimitris Petridis, Christos Ritzoulis, Kaid Darwiche, Dionysis Spyratos, Haidong Huang, Eugene P. Goldberg, Lonny Yarmus, Qiang Li, Lutz Freitag & Konstantinos Zarogoulidis. (2013) Establishing the optimal nebulization system for paclitaxel, docetaxel, cisplatin, carboplatin and gemcitabine: Back to drawing the residual cup. International Journal of Pharmaceutics 453:2, pages 480-487.
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Eng-Seng Chan, Tek-Kaun Lim, Pogaku Ravindra, Rachel Fran Mansa & Aminul Islam. (2012) The effect of low air-to-liquid mass flow rate ratios on the size, size distribution and shape of calcium alginate particles produced using the atomization method. Journal of Food Engineering 108:2, pages 297-303.
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A. Sohail, B. Bhandari, M.S. Turner & A.G.A. Coombes. (2012) Direct encapsulation of small molecule hydrophilic and hydrophobic actives in alginate microspheres using a novel impinging aerosols method. Journal of Drug Delivery Science and Technology 22:2, pages 139-143.
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