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Journal of Drug Targeting Volume 21, 2013 - Issue 1
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Research Article

Formulation and evaluation of carnosic acid nanoparticulate system for upregulation of neurotrophins in the brain upon intranasal administration

Siva Ram Kiran VakaDepartment of Pharmaceutics, The University of Mississippi School of Pharmacy, University, MS, USA
,
H.N. ShivakumarDepartment of Pharmaceutics, KLE University’s College of Pharmacy, Bengaluru, Karnataka, India
,
Michael A. RepkaDepartment of Pharmaceutics, The University of Mississippi School of Pharmacy, University, MS, USA
&
S. Narasimha MurthyDepartment of Pharmaceutics, The University of Mississippi School of Pharmacy, University, MS, USACorrespondence[email protected]
Pages 44-53 | Received 29 Jun 2012, Accepted 27 Aug 2012, Published online: 01 Oct 2012

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Chenchen Bi, Aiping Wang, Yongchao Chu, Sha Liu, Hongjie Mu, Wanhui Liu, Zimei Wu, Kaoxiang Sun & Youxin Li. (2016) Intranasal delivery of rotigotine to the brain with lactoferrin-modified PEG-PLGA nanoparticles for Parkinson’s disease treatment. International Journal of Nanomedicine 11, pages 6547-6559.
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Bo Tang, Fang Tang, Zhenran Wang, Guangying Qi, Xingsi Liang, Bo Li, Shengguang Yuan, Jie Liu, Shuiping Yu & Songqing He. (2016) Upregulation of Akt/NF-κB-regulated inflammation and Akt/Bad-related apoptosis signaling pathway involved in hepatic carcinoma process: suppression by carnosic acid nanoparticle. International Journal of Nanomedicine 11, pages 6401-6420.
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Articles from other publishers (13)

Sumaia Abdulbari Ahmed Ali Hard, H.N. Shivakumar & Moqbel Ali Moqbel Redhwan. (2023) Development and optimization of in-situ gel containing chitosan nanoparticles for possible nose-to-brain delivery of vinpocetine. International Journal of Biological Macromolecules 253, pages 127217.
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Dhruti Avlani, Avichal Kumar & Shivakumar H.N. (2023) Development of Dispersible Vaginal Tablets of Tenofovir Loaded Mucoadhesive Chitosan Microparticles for Anti-HIV Pre-Exposure Prophylaxis. Molecular Pharmaceutics.
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Chhavi Bhalothia & Girima Nagda. (2022) Nanotherapeutics a promising approach for treatment of Parkinson’s disease. Materials Today: Proceedings 69, pages A1-A13.
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Jyotsna Shankar, Geetha K.M & Barnabas Wilson. (2021) Potential applications of nanomedicine for treating Parkinson's disease. Journal of Drug Delivery Science and Technology 66, pages 102793.
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Jheel Dholakia, Bala Prabhakar & Pravin Shende. (2021) Strategies for the delivery of antidiabetic drugs via intranasal route. International Journal of Pharmaceutics 608, pages 121068.
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Marcos Roberto de Oliveira. 2021. Mitochondrial Physiology and Vegetal Molecules. Mitochondrial Physiology and Vegetal Molecules 191 208 .
Magisetty Obulesu. 2020. Parkinson's Disease Therapeutics. Parkinson's Disease Therapeutics 89 101 .
Marcos Roberto de Oliveira. (2018) Carnosic Acid as a Promising Agent in Protecting Mitochondria of Brain Cells. Molecular Neurobiology 55:8, pages 6687-6699.
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Marcos Roberto de Oliveira, Gustavo da Costa Ferreira, Alessandra Peres & Simone Morelo Dal Bosco. (2017) Carnosic Acid Suppresses the H2O2-Induced Mitochondria-Related Bioenergetics Disturbances and Redox Impairment in SH-SY5Y Cells: Role for Nrf2. Molecular Neurobiology 55:2, pages 968-979.
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Hui Li, Jian-Jun Sun, Guo-Yong Chen, Wei-Wei Wang, Zhan-Tao Xie, Gao-Feng Tang & Si-Dong Wei. (2016) Carnosic acid nanoparticles suppress liver ischemia/reperfusion injury by inhibition of ROS, Caspases and NF-κB signaling pathway in mice. Biomedicine & Pharmacotherapy 82, pages 237-246.
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Yosra S.R. Elnaggar, Samar M. Etman, Doaa A. Abdelmonsif & Ossama Y. Abdallah. (2015) Intranasal Piperine-Loaded Chitosan Nanoparticles as Brain-Targeted Therapy in Alzheimer's Disease: Optimization, Biological Efficacy, and Potential Toxicity. Journal of Pharmaceutical Sciences 104:10, pages 3544-3556.
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Jayrajsinh Sarvaiya & Y.K. Agrawal. (2015) Chitosan as a suitable nanocarrier material for anti-Alzheimer drug delivery. International Journal of Biological Macromolecules 72, pages 454-465.
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Meenakshi Malhotra, Catherine Tomaro-Duchesneau, Shyamali Saha & Satya Prakash. 2014. Drug Delivery System. Drug Delivery System 233 247 .

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