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Research Article

Decreased expression of apelin in placentas from severe pre-eclampsia patients

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Pages 410-421 | Received 11 Jan 2013, Accepted 05 Jun 2013, Published online: 11 Jul 2013

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Read on this site (4)

Rajeev Gandham, C. D. Dayanand, S. R. Sheela & P. Kiranmayee. (2022) Maternal serum Apelin 13 and APLN gene promoter variant -1860T > C in preeclampsia. The Journal of Maternal-Fetal & Neonatal Medicine 35:25, pages 5008-5016.
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Marta Fuentes-Carrasco, Rebeca Ruíz-Román, Ricardo Savirón-Cornudella, Gonzalo Pérez-Roncero, María T. López-Baena & Faustino R. Pérez-López. (2022) Systematic review and meta-analysis regarding maternal apelin in pregnant women with and without preeclampsia. Gynecological Endocrinology 38:11, pages 918-927.
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Aamal Sattar Taha, Zohreh Zahraei & Hussein Kadhem Al-Hakeim. (2020) Serum apelin and galectin-3 in preeclampsia in Iraq. Hypertension in Pregnancy 39:4, pages 379-386.
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Rulin Deniz, Yakup Baykus, Sefer Ustebay, Kader Ugur, Şeyda Yavuzkir & Suleyman Aydin. (2019) Evaluation of elabela, apelin and nitric oxide findings in maternal blood of normal pregnant women, pregnant women with pre-eclampsia, severe pre-eclampsia and umbilical arteries and venules of newborns. Journal of Obstetrics and Gynaecology 39:7, pages 907-912.
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Articles from other publishers (39)

Fiona A Chapman, Janet J Maguire, David E Newby, Anthony P Davenport & Neeraj Dhaun. (2023) Targeting the apelin system for the treatment of cardiovascular diseases. Cardiovascular Research.
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Lingyu Ye, Yujia Huang, Xueqing Liu, Xinyu Zhang, Yang Cao, Xiangju Kong, Xiaolei Yuan, Jie Xu & Hui Zhu. (2023) Apelin/APJ system protects placental trophoblasts from hypoxia-induced oxidative stress through activating PI3K/Akt signaling pathway in preeclampsia. Free Radical Biology and Medicine 208, pages 759-770.
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Rahim KOCABAŞ, Melike GEYİK BAYMAN, Fatih ZEYTİN, Ercan KARABULUT & Mehmet AKÖZ. (2023) PLAZMA APELİN DÜZEYİ VE PRE-EKLAMPSİ VAKALARI ARASINDAKİ BAĞLANTININ ARAŞTIRILMASIINVESTIGATION OF THE RELATIONSHIP BETWEEN PLASMA APELIN LEVEL AND PRE-ECLAMPSIA CASES. SDÜ Tıp Fakültesi Dergisi 30:2, pages 211-216.
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Ana Paula dos Santos Xavier Braga, Diana Matos Silva, Deborah de Farias Lelis, Rogério Estevam Farias, Alanna Fernandes Paraíso, Sérgio Henrique Sousa Santos, Andrea Maria Eleutério de Barros Lima Martins & João Marcus Oliveira Andrade. (2023) Apelin and Visfatin Expression in Placental Tissue in Women With Preeclampsia and Overweight/Obesity. Biological Research For Nursing, pages 109980042311788.
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Océane Pécheux, Ana Correia-Branco, Marie Cohen & Begoῆa Martinez de Tejada. (2023) The Apelinergic System in Pregnancy. International Journal of Molecular Sciences 24:9, pages 8014.
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Benedetta Fibbi, Giada Marroncini, Laura Naldi & Alessandro Peri. (2023) The Yin and Yang Effect of the Apelinergic System in Oxidative Stress. International Journal of Molecular Sciences 24:5, pages 4745.
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Cemre Nur Balci, Ezgi Golal, Ismail Ustunel & Nuray Acar. (2023) The investigation of apelin and apelin receptor expressions in mouse endometrium during peri-implantation period. Annals of Anatomy - Anatomischer Anzeiger 246, pages 152027.
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Luca Ferrari, Simona Iodice, Laura Cantone, Giulia Solazzo, Laura Dioni, Mirjam Hoxha, Marco Vicenzi, Paola Mozzoni, Enrico Bergamaschi, Nicola Persico & Valentina Bollati. (2022) Extracellular vesicles and their miRNA contents counterbalance the pro-inflammatory effect of air pollution during physiological pregnancy: A focus on Syncytin-1 positive vesicles. Environment International 169, pages 107502.
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Hamed Alizadeh Pahlavani. (2022) Possible roles of exercise and apelin against pregnancy complications. Frontiers in Endocrinology 13.
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Rafal Sibiak. (2022) ELABELA as a Marker of Gestational Complications – A Review. Medical Journal of Cell Biology 10:2, pages 43-48.
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Monika Dawid, Ewa Mlyczyńska, Małgorzata Jurek, Natalia Respekta, Karolina Pich, Patrycja Kurowska, Wiktoria Gieras, Tomasz Milewicz, Małgorzata Kotula-Balak & Agnieszka Rak. (2021) Apelin, APJ, and ELABELA: Role in Placental Function, Pregnancy, and Foetal Development—An Overview. Cells 11:1, pages 99.
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Reham Z. Hamza, Abdel Aziz A. Diab, Mansour H. Zahra, Ali K. Asalah, Suzan M. M. Moursi, Najah M. Al-Baqami, Fawziah A. Al-Salmi & Mai S. Attia. (2021) Correlation between Apelin and Some Angiogenic Factors in the Pathogenesis of Preeclampsia: Apelin-13 as Novel Drug for Treating Preeclampsia and Its Physiological Effects on Placenta. International Journal of Endocrinology 2021, pages 1-12.
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Aleksandra Stupak, Wojciech Kwaśniewski, Anna Goździcka-Józefiak & Anna Kwaśniewska. (2021) The Influence of Maternal Obesity on Cell-Free Fetal DNA and Blood Pressure Regulation in Pregnancies with Hypertensive Disorders. Medicina 57:9, pages 962.
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Nevin TÜTEN, Koray GÖK, Mine KUCUR, Abdullah AÇIKGÖZ, Abdullah TÜTEN & Mahmut ONCUL. (2021) Fetal Gelişim ve Büyümede Apelinin Rolü. Sakarya Medical Journal.
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Sahar Mazloomi, Iraj Khodadadi, Narges Alizadeh & Gholamreza Shafiee. (2021) Association of glutamate cystein ligase (GCL) activity Peroxiredoxin 4 (prxR4) and apelin levels in women with preeclampsia. Pregnancy Hypertension 23, pages 163-168.
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K.Y. Boyarsky, E.I. Kahiani, O.S. Arnt & A.A. Zhdanova. (2021) The role of the apelinergic system in human reproduction (literature review). Problemy reproduktsii 27:4, pages 50.
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Rajeev Gandham, C.D. Dayanand, S.R. SheelaKiranmayee Pamidimukkala. (2020) Impact of Oxidative Stress on Maternal Serum Apelin 13 and Endothelial Nitric Oxide Synthase in Preeclampsia. Biomedical and Pharmacology Journal 13:4, pages 2041-2048.
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Paweł Gutaj, Rafał Sibiak, Maurycy Jankowski, Karina Awdi, Rut Bryl, Paul Mozdziak, Bartosz Kempisty & Ewa Wender-Ozegowska. (2020) The Role of the Adipokines in the Most Common Gestational Complications. International Journal of Molecular Sciences 21:24, pages 9408.
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Xueying Wang, Xiaofei Liu, Zifan Song, Xin Shen, Siying Lu, Yan Ling & Haibin Kuang. (2020) Emerging roles of APLN and APELA in the physiology and pathology of the female reproductive system. PeerJ 8, pages e10245.
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Zain Awamleh & Victor K. M. Han. (2020) Potential pathophysiological role of microRNA 193b-5p in human placentae from pregnancies complicated by preeclampsia and intrauterine growth restriction. Molecular Biology Reports 47:9, pages 6531-6544.
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A. Troisi, C. Dall’Aglio, M. Maranesi, R. Orlandi, R. Speranza, M. Zerani & A. Polisca. (2020) Presence and expression of apelin and apelin receptor in bitch placenta. Theriogenology 147, pages 192-196.
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Beril Gürlek, Adnan Yılmaz, Murtaza E. Durakoğlugil, Sibel Karakaş, İlknur M. Kazaz, Özgür Önal & Ömer Şatıroğlu. (2019) Evaluation of serum apelin‐13 and apelin‐36 concentrations in preeclamptic pregnancies. Journal of Obstetrics and Gynaecology Research 46:1, pages 58-65.
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Zain Awamleh, Gregory B. Gloor & Victor K. M. Han. (2019) Placental microRNAs in pregnancies with early onset intrauterine growth restriction and preeclampsia: potential impact on gene expression and pathophysiology. BMC Medical Genomics 12:1.
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Danai Georgiadou, Gijs B. Afink & Marie van Dijk. (2019) The apelinergic-axis in human preeclamptic pregnancies: A systematic review. Pregnancy Hypertension 17, pages 148-157.
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Liliya M. Yamaleyeva, K. Bridget Brosnihan, Ebrahim Elsangeedy, Carolynne McGee, Sara Shi, David Caudell, Cynthia Miller, Jasmina Varagic, Michael Bader, Ralf Dechend & Hossam A. Shaltout. (2019) Systemic Outcomes of (Pyr1)-Apelin-13 Infusion at Mid-Late Pregnancy in a Rat Model with Preeclamptic Features. Scientific Reports 9:1.
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O.R. Vaughan, T.L. Powell & T. Jansson. (2019) Apelin is a novel regulator of human trophoblast amino acid transport. American Journal of Physiology-Endocrinology and Metabolism 316:5, pages E810-E816.
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Delphine Eberlé, Lucie Marousez, Sandy Hanssens, Claude Knauf, Christophe Breton, Philippe Deruelle & Jean Lesage. (2019) Elabela and Apelin actions in healthy and pathological pregnancies. Cytokine & Growth Factor Reviews 46, pages 45-53.
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Madeline Rose Keleher, Rabab Zaidi, Shyam Shah, M. Elsa Oakley, Cassondra Pavlatos, Samir El Idrissi, Xiaoyun Xing, Daofeng Li, Ting Wang & James M. Cheverud. (2018) Maternal high-fat diet associated with altered gene expression, DNA methylation, and obesity risk in mouse offspring. PLOS ONE 13:2, pages e0192606.
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Katsuhiko Naruse. 2018. Preeclampsia. Preeclampsia 113 124 .
Chengshu Wang, Xiaoli Liu, Desheng Kong, Xijing Qin, Yanqing Li, Xu Teng & Xianghua Huang. (2017) Apelin as a novel drug for treating preeclampsia. Experimental and Therapeutic Medicine.
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Jeffrey S Gilbert. (2017) From apelin to exercise: emerging therapies for management of hypertension in pregnancy. Hypertension Research 40:6, pages 519-525.
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Kirk P. Conrad. (2016) G-Protein-coupled receptors as potential drug candidates in preeclampsia: targeting the relaxin/insulin-like family peptide receptor 1 for treatment and prevention. Human Reproduction Update 22:5, pages 647-664.
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Tim Van Mieghem, Anne Doherty, Dora Baczyk, Sascha Drewlo, David Baud, Jose Carvalho & John Kingdom. (2016) Apelin in Normal Pregnancy and Pregnancies Complicated by Placental Insufficiency. Reproductive Sciences 23:8, pages 1037-1043.
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Dennis K. Lee & Ori Nevo. (2016) Microvascular endothelial cells from preeclamptic women exhibit altered expression of angiogenic and vasopressor factors. American Journal of Physiology-Heart and Circulatory Physiology 310:11, pages H1834-H1841.
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Haley R. Eidem, David C. Rinker, William E. AckermanIVIV, Irina A. Buhimschi, Catalin S. Buhimschi, Caitlin Dunn-Fletcher, Suhas G. Kallapur, Mihaela Pavličev, Louis J. Muglia, Patrick Abbot & Antonis Rokas. (2016) Comparing human and macaque placental transcriptomes to disentangle preterm birth pathology from gestational age effects. Placenta 41, pages 74-82.
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Qun Zhou, Jiangang Cao & Linxi Chen. (2016) Apelin/APJ system: A novel therapeutic target for oxidative stress-related inflammatory diseases�(Review). International Journal of Molecular Medicine.
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Irina A. Polejaeva, Heloisa M. Rutigliano & Kevin D. Wells. (2016) Livestock in biomedical research: history, current status and future prospective. Reproduction, Fertility and Development 28:2, pages 112.
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Liliya M. YamaleyevaMark C. ChappellK. Bridget BrosnihanLauren AntonDavid L. Caudell, Sara ShiCarolynne McGeeNancy PirroPatricia E. GallagherRobert N. Taylor, David C. Merrill & Heather L. Mertz. (2015) Downregulation of apelin in the human placental chorionic villi from preeclamptic pregnancies. American Journal of Physiology-Endocrinology and Metabolism 309:10, pages E852-E860.
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Bálint Alasztics, Nóra Gullai, Attila Molvarec & János Rigó Jr.. (2014) The role of angiogenic factors in preeclampsia. Orvosi Hetilap 155:47, pages 1860-1866.
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