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Original Article

Prophylactic Anticonvulsant Therapy in Hypertensive Crises of Pregnancy—The Need for a Large, Randomized Trial

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Pages 245-252 | Published online: 07 Jul 2009

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Ali Kolusari, Mertihan Kurdoglu, Guler Bugdayci, Ertan Adali, Recep Yildizhan, Ayşegul Cebi, Halit Demir, Guler Sahin & Mansur Kamaci. (2009) Relationship between erythrocyte catalase and serum adenosine deaminase activities in eclampsia. The Journal of Maternal-Fetal & Neonatal Medicine 22:4, pages 321-324.
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Vedat Dayicioglu, Zeki Sahinoglu, Emrah Kol & Mehmet Kucukbas. (2003) The Use of Standard Dose of Magnesium Sulphate in Prophylaxis of Eclamptic Seizures: Do Body Mass Index Alterations Have Any Effect on Success?. Hypertension in Pregnancy 22:3, pages 257-265.
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Rani Lewis & Baha Sibai. (1997) Recent Advances in the Management of Preeclampsia. Journal of Maternal-Fetal Medicine 6:1, pages 6-15.
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James J. Walker. (1996) Magnesium Sulfate is the Drug of Choice for the Treatment of Eclampsia. Hypertension in Pregnancy 15:1, pages 1-6.
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Articles from other publishers (45)

Kristen Cagino, Malavika Prabhu & Baha Sibai. (2023) Is magnesium sulfate therapy warranted in all cases of late postpartum severe hypertension? A suggested approach to a clinical conundrum. American Journal of Obstetrics and Gynecology 229:6, pages 641-646.
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Marie-Pierre Bonnet, Marc Garnier, Hawa Keita, Vincent Compère, Chloé Arthuis, Tiphaine Raia-Barjat, Paul Berveiller, Julien Burey, Lionel Bouvet, Marie Bruyère, Adeline Castel, Elodie Clouqueur, Max Gonzalez Estevez, Valentina Faitot, Catherine Fischer, Florent Fuchs, Edouard Lecarpentier, Agnès Le Gouez, Agnès Rigouzzo, Mathias Rossignol, Emmanuel Simon, Florence Vial, Alexandre Vivanti, Laurent Zieleskewicz, Marie-Victoire Sénat, Thomas Schmitz & Loïc Sentilhes. (2023) Republication de : recommandations formalisées d’experts. Prise en charge de la patiente avec une pré-éclampsie sévère. Anesthésie & Réanimation 9:4, pages 336-365.
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Emily Shepherd, Rehana A. Salam, Deepak Manhas, Anne Synnes, Philippa Middleton, Maria Makrides & Caroline A. Crowther. (2019) Antenatal magnesium sulphate and adverse neonatal outcomes: A systematic review and meta-analysis. PLOS Medicine 16:12, pages e1002988.
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Anne Cathrine Staff, Baha M. Sibai & F.Gary Cunningham. 2015. Chesley's Hypertensive Disorders in Pregnancy. Chesley's Hypertensive Disorders in Pregnancy 253 267 .
Emily S Bain, Philippa F Middleton & Caroline A Crowther. (2013) Maternal adverse effects of different antenatal magnesium sulphate regimens for improving maternal and infant outcomes: a systematic review. BMC Pregnancy and Childbirth 13:1.
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Thuy-My N Nguyen, Caroline A Crowther, Dominic Wilkinson & Emily Bain. (2013) Magnesium sulphate for women at term for neuroprotection of the fetus. Cochrane Database of Systematic Reviews.
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C. Dean & J. Douglas. (2013) Magnesium and the obstetric anaesthetist. International Journal of Obstetric Anesthesia 22:1, pages 52-63.
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Susanne Herroeder, Marianne E. Schönherr, Stefan G. De Hert & Markus W. Hollmann. (2011) Magnesium—Essentials for Anesthesiologists. Anesthesiology 114:4, pages 971-993.
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Laura M. Héman & Paul J. Q. Van Der Linden. (2011) Does magnesium sulfate increase the incidence of postpartum hemorrhage? A systematic review. Open Journal of Obstetrics and Gynecology 01:04, pages 168-173.
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Lelia Duley, A Metin Gülmezoglu, David J Henderson-Smart & Doris Chou. (2010) Magnesium sulphate and other anticonvulsants for women with pre-eclampsia. Cochrane Database of Systematic Reviews.
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Lelia Duley, Hosam E Matar, Muhammad Qutayba Almerie & David R Hall. (2010) Alternative magnesium sulphate regimens for women with pre-eclampsia and eclampsia. Cochrane Database of Systematic Reviews 2011:4.
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Linda S. Polley. 2009. Chestnut's Obstetric Anesthesia: Principles and Practice. Chestnut's Obstetric Anesthesia: Principles and Practice 975 1007 .
Baha M. Sibai & F. Gary Cunningham. 2009. Chesley's Hypertensive Disorders in Pregnancy. Chesley's Hypertensive Disorders in Pregnancy 213 225 .
Baha M. Sibai. 2007. Obstetrics: Normal and Problem Pregnancies. Obstetrics: Normal and Problem Pregnancies 863 912 .
Frederick U. Eruo & Baha M. Sibai. 2007. Clinical Obstetrics. Clinical Obstetrics 683 699 .
Michael A. Belfort, Steven L. Clark & Baha Sibai. (2006) Cerebral Hemodynamics in Preeclampsia: Cerebral Perfusion and the Rationale for an Alternative to Magnesium Sulfate. Obstetrical & Gynecological Survey 61:10, pages 655-665.
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P. Rozenberg. (2006) Int?r?t du sulfate de magn?sium dans la prise en charge de la pr??clampsie. Gyn?cologie Obst?trique & Fertilit? 34:1, pages 54-59.
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B. Haddad, M. Beaufils & F. Bavoux. (2006) Tratamiento de la preeclampsia. EMC - Ginecolog?a-Obstetricia 42:4, pages 1-15.
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B. Haddad, M. Beaufils & F. Bavoux. (2006) Prise en charge de la pr??clampsie. EMC - Obst?trique 1:3, pages 1-14.
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Baha M Sibai. (2005) Magnesium Sulfate Prophylaxis in Preeclampsia: Evidence From Randomized Trials. Clinical Obstetrics and Gynecology 48:2, pages 478-488.
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Lelia Duley. (2005) Evidence and practice: the magnesium sulphate story. Best Practice & Research Clinical Obstetrics & Gynaecology 19:1, pages 57-74.
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Baha M Sibai. (2004) Magnesium sulfate prophylaxis in preeclampsia: lessons learned from recent trials. American Journal of Obstetrics and Gynecology 190:6, pages 1520-1526.
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Dominique ?douard. (2004) Pr??clampsie. ?clampsie. EMC - Anesth?sie-R?animation 1:1, pages 1-15.
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Lelia Duley, A Metin Gülmezoglu & David J Henderson-Smart. 1996. Cochrane Database of Systematic Reviews. Cochrane Database of Systematic Reviews.
D. ?douard. (2003) Preeclampsia. Eclampsia. EMC - Anestesia-Reanimaci?n 29:3, pages 1-15.
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Andrea Witlin. 2002. Hypertension in Pregnancy. Hypertension in Pregnancy 221 234 .
Gus Dekker & Baha Sibai. (2001) Primary, secondary, and tertiary prevention of pre-eclampsia. The Lancet 357:9251, pages 209-215.
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D. R. Hall, H. J. Odendaal & M. Smith. (2000) Is the prophylactic administration of magnesium sulphate in women with pre-eclampsia indicated prior to labour?. BJOG: An International Journal of Obstetrics and Gynaecology 107:7, pages 903-908.
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J. G. Thornton. (2000) Prophylactic anticonvulsants for pre-eclampsia?. BJOG: An International Journal of Obstetrics and Gynaecology 107:7, pages 839-840.
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D. R. Hall, H. J. Odendaal, D. W. Steyn & M. Smith. (2005) Nifedipine or prazosin as a second agent to control early severe hypertension in pregnancy: a randomised controlled trial. BJOG: An International Journal of Obstetrics & Gynaecology 107:6, pages 759-765.
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Vern L. Katz, Richard Farmer & Jeffery A. Kuller. (2000) Preeclampsia into eclampsia: Toward a new paradigm. American Journal of Obstetrics and Gynecology 182:6, pages 1389-1396.
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James J. Walker. (2000) Severe pre-eclampsia and eclampsia. Best Practice & Research Clinical Obstetrics & Gynaecology 14:1, pages 57-71.
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ANDREA G. WITLIN. (1999) Prevention and Treatment of Eclamptic Convulsions. Clinical Obstetrics and Gynecology 42:3, pages 507.
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Lelia Duley, Barbara Farrell & James P. Neilson. (2005) Magnesium sulphate: a review of clinical pharmacology applied to obstetrics. BJOG: An International Journal of Obstetrics & Gynaecology 106:2, pages 180-180.
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Michael A. Belfort, John Anthony & George R. Saade. (1999) Prevention of eclampsia. Seminars in Perinatology 23:1, pages 65-78.
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J. Moodley. (1998) Magnesium sulphate in clinical practice: an obstetrician's viewpoint. International Journal of Obstetric Anesthesia 7:2, pages 73-75.
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C. R. Leitch, A. D. Cameron & J. J. Walker. (2005) The changing pattern of eclampsia over a 60‐year period. BJOG: An International Journal of Obstetrics & Gynaecology 104:8, pages 917-922.
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Patrick F. W. Chien & Khalid S. Khan. (2005) A uthors' reply . BJOG: An International Journal of Obstetrics & Gynaecology 104:6, pages 757-758.
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Lelia Duley & Jim Neilson. (2005) Magnesium sulphate in the treatment of eclampsia and pre‐eclampsia: an overview of the evidence from randomised trials. BJOG: An International Journal of Obstetrics & Gynaecology 104:6, pages 756-757.
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Andrea G. Witlin, Steven A. Friedman & Baha M. Sibai. (1997) The effect of magnesium sulfate therapy on the duration of labor in women with mild preeclampsia at term: A randomized, double-blind, placebo-controlled trial. American Journal of Obstetrics and Gynecology 176:3, pages 623-627.
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S.M. Khedun, J. Moodley, T. Naicker & B. Maharaj. (1997) Drug management of hypertensive disorders of pregnancy. Pharmacology & Therapeutics 74:2, pages 221-258.
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Baha M. Sibai. (1996) Treatment of Hypertension in Pregnant Women. New England Journal of Medicine 335:4, pages 257-265.
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James J. Walker. (1996) Care of the patient with severe pregnancy induced hypertension. European Journal of Obstetrics & Gynecology and Reproductive Biology 65:1, pages 127-135.
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S. C. Robson. (1996) Magnesium sulphate: the time of reckoning. BJOG: An International Journal of Obstetrics and Gynaecology 103:2, pages 99-102.
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R.F. Burrows & E.A. Burrows. (1996) The need for seizure prophylaxis in preeclampsia is still unresolved. American Journal of Obstetrics and Gynecology 174:2, pages 800-801.
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