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Clinical and Experimental Hypertension Volume 33, 2011 - Issue 3
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Research Article

Efficacy and Tolerability of a Single-Pill Combination of Amlodipine/Valsartan in Asian Hypertensive Patients Not Adequately Controlled with Valsartan Monotherapy

Jun Huang The First Affiliated Hospital with Nanjing Medical University, Nanjing, China
,
Ning-Ling Sun Peking University People's Hospital, Beijing, China
,
Yu-Ming Hao The Second Hospital of Hebei Medical University, Shijiazhuang, China
,
Jun-Ren Zhu Zhongshan Hospital Fudan University, Shanghai, ChinaCorrespondence[email protected]
,
Yingmei Tu Beijing Novartis Pharma Co Ltd, Beijing, China
,
Valentin Curt Novartis Pharmaceuticals Corporation, East Hanover, New Jersey, USA
,
Ying Zhang Novartis Pharmaceuticals Corporation, East Hanover, New Jersey, USA
& on Behalf the Trial Investigators show all
Pages 179-186 | Received 28 Apr 2010, Accepted 24 Jun 2010, Published online: 05 Apr 2011

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Yong Huo, Ye Gu, Genshan Ma, Jincheng Guo, Longgen Xiong, Zhurong Luo, Jianhong Xie, Weimin Li, Jianrong Zhao, Xiaowei Yan, Wei Liu, Yawei Xu, Xiaomei Bao, Luosha Zhao, Ming Yang, Bei Wang & The China STATUS III Study Group. (2019) China STudy of valsartan/amlodipine fixed-dose combination-bAsed long-Term blood pressUre management in HypertenSive patients: a one-year registry (China STATUS III). Current Medical Research and Opinion 35:8, pages 1441-1449.
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Sverre E. Kjeldsen, Franz H. Messerli, Chern-En Chiang, Peter A. Meredith & Lisheng Liu. (2012) Are fixed-dose combination antihypertensives suitable as first-line therapy?. Current Medical Research and Opinion 28:10, pages 1685-1697.
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Articles from other publishers (15)

Mengxin Xie, Tianjiao Tang & Hongsheng Liang. (2023) Efficacy of single‐pill combination in uncontrolled essential hypertension: A systematic review and network meta‐analysis. Clinical Cardiology.
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Weiliang Zhang, Yongbin Song & Jiangtao Xu. (2017) Effectiveness and safety of valsartan/amlodipine in hypertensive patients with stroke. Medicine 96:26, pages e7172.
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Ningling Sun, Yingqing Feng, Pingjin Gao, Xiaoping Chen, Litong Qi, Shuyang Zhang, Yugang Dong, Xinchun Yang, Xinli Li, Yundai Chen & Lingli Liu. (2017) Efficacy and tolerability of once-daily 160 mg valsartan in Chinese patients with mild to moderate hypertension. Experimental and Therapeutic Medicine 13:3, pages 1109-1116.
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Muhammad Ali Sheraz, Syed Furqan Ahsan, Marium Fatima Khan, Sofia Ahmed & Iqbal Ahmad. (2016) Formulations of Amlodipine: A Review. Journal of Pharmaceutics 2016, pages 1-11.
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Beihai Ge, Wenzhong Peng, Yi Zhang, Yuxiang Wen, Cong Liu & Xiaomei Guo. (2015) Effectiveness of Valsartan/Amlodipine Single-pill Combination in Hypertensive Patients With Excess Body Weight. Journal of Cardiovascular Pharmacology 66:5, pages 497-503.
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Dayi Hu, Lisheng Liu & Weimin Li. (2014) Efficacy and Safety of Valsartan/Amlodipine Single-Pill Combination in 11,422 Chinese Patients with Hypertension: an Observational Study. Advances in Therapy 31:7, pages 762-775.
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Waheed Khan, Nasir Moin, Somia Iktidar, Javed Sakrani, Rizwan Abid, Javed Afzal, Neeta Maheshwary, Kishore Kumar, Ahson Siddiqi & Murad Qadir. (2014) Real-life effectiveness, safety, and tolerability of amlodipine/valsartan or amlodipine/valsartan/hydrochlorothiazide single-pill combination in patients with hypertension from Pakistan. Therapeutic Advances in Cardiovascular Disease 8:2, pages 45-55.
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Hee Youn Choi, Yo Han Kim, Mi Jo Kim, Yook-Hwan Noh, Shi Hyang Lee, Kyun-Seop Bae & Hyeong-Seok Lim. (2013) Pharmacokinetics, Tolerability, and Safety of the Single Oral Administration of AGSAV301 vs Exforge: A Randomized Crossover Study of Healthy Male Volunteers. American Journal of Cardiovascular Drugs 14:1, pages 63-72.
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Keith C. Ferdinand & Samar A. Nasser. (2013) A Review of the Efficacy and Tolerability of Combination Amlodipine/Valsartan in Non-White Patients with Hypertension. American Journal of Cardiovascular Drugs 13:5, pages 301-313.
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Dingliang Zhu, Kan Yang, Ningling Sun, Pingjin Gao, Ruonan Wang, Amie Grosso & Ying Zhang. (2013) Amlodipine/valsartan 5/160mg versus valsartan 160mg in Chinese hypertensives. International Journal of Cardiology 167:5, pages 2024-2030.
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Ji-Guang Wang, Wei-Fang Zeng, Yu-Song He, Liang-Long Chen, Meng Wei, Zhao-Ping Li, Bao-Wei Zhang & Yan Li. (2013) Valsartan/Amlodipine Compared to Nifedipine GITS in Patients with Hypertension Inadequately Controlled by Monotherapy. Advances in Therapy 30:8, pages 771-783.
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Yuan‐Nan Ke, Yu‐Gang Dong, Shu‐Ping Ma, Hong Yuan, Sang‐Hyun Ihm & Sang Hong Baek. (2012) Improved Blood Pressure Control with Nifedipine GITS /Valsartan Combination Versus High‐Dose Valsartan Monotherapy in Mild‐to‐Moderate Hypertensive Patients from Asia: Results from the ADVISE Study, a Randomized Trial . Cardiovascular Therapeutics 30:6, pages 326-332.
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. (2012) Current World Literature. Current Opinion in Nephrology & Hypertension 21:5, pages 557-566.
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Dingliang L. Zhu, Harold Bays, Pingjin Gao, Michaela Mattheus, Birgit Voelker & Luis M. Ruilope. (2012) Efficacy and Tolerability of Initial Therapy With Single-Pill Combination Telmisartan/Hydrochlorothiazide 80/25 mg in Patients With Grade 2 or 3 Hypertension: A Multinational, Randomized, Double-Blind, Active-Controlled Trial. Clinical Therapeutics 34:7, pages 1613-1624.
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Yuri Karpov, Neelesh Dongre, Alexey Vigdorchik & Krisada Sastravaha. (2012) Amlodipine/Valsartan Single-Pill Combination: A Prospective, Observational Evaluation of the Real-Life Safety and Effectiveness in the Routine Treatment of Hypertension. Advances in Therapy 29:2, pages 134-147.
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