385
Views
32
CrossRef citations to date
0
Altmetric
Research Article

Role of ROS in the protective effect of silibinin on sodium nitroprusside-induced apoptosis in rat pheochromocytoma PC12 cells

, , , , , , & show all
Pages 835-847 | Received 17 Jan 2011, Accepted 07 Apr 2011, Published online: 13 May 2011

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (8)

Özlem Öz Gergin, İsmail Şamil Gergin, Sibel Seckin Pehlivan, Ozge Cengiz Mat, Işıl Tuğçe Turan, Adnan Bayram, Zeynep Burçin Gönen, Şeyda Korkmaz, Cihangir Bıcer, Karamehmet Yildiz & Arzu Hanım Yay. (2023) The neuroprotective effect of mesenchymal stem cells in colistin-induced neurotoxicity. Toxicology Mechanisms and Methods 33:2, pages 95-103.
Read now
Yunxia Li, Xin Chen, Wei He, Shuyue Xia, Xiaochuan Jiang, Xiaoyang Li, Jiayu Bai, Nan Li, Lei Chen & Biao Yang. (2021) Apigenin Enhanced Antitumor Effect of Cisplatin in Lung Cancer via Inhibition of Cancer Stem Cells. Nutrition and Cancer 73:8, pages 1489-1497.
Read now
Erjie Tian, Wanjun Hu, Yusong Miao, Ishfaq Muhammad, Ling Zhang, Chunli Xia, Liangjun Ding, Qiaomei Zhang, Rui Li, Chunli Chen & Jichang Li. (2019) Preventive effects of nerve growth factor against colistin-induced autophagy and apoptosis in PC12 cells. Toxicology Mechanisms and Methods 29:3, pages 177-186.
Read now
Xiaoling Liu, Xinyu Long, Weiwei Liu, Guodong Yao, Yeli Zhao, Toshihiko Hayashi, Shunji Hattori, Hitomi Fujisaki, Takaaki Ogura, Shin-ichi Tashiro, Satoshi Onodera, Masayuki Yamato & Takashi Ikejima. (2018) Differential levels of reactive oxygen species in murine preadipocyte 3T3-L1 cells cultured on type I collagen molecule-coated and gel-covered dishes exert opposite effects on NF-κB-mediated proliferation and migration. Free Radical Research 52:9, pages 913-928.
Read now
Minxue Lian, Xiaodong Zhang, Hui Wang, Hao Liu, Wei Chen & Shiwen Guo. (2014) Increased 8-hydroxydeoxyguanosine in high-grade gliomas is associated with activation of autophagy. International Journal of Neuroscience 124:12, pages 926-934.
Read now
J. W. Li, N. Ning, Y. Z. Ma, R. Zhang, F. Tan & N. H. Chen. (2013) Claulansine F suppresses apoptosis induced by sodium nitroprusside in PC12 cells. Free Radical Research 47:6-7, pages 488-497.
Read now
Yang Yu, Si Miao Fan, Su Juan Yuan, Shin-Ichi Tashiro, Satoshi Onodera & Takashi Ikejima. (2012) Nitric oxide (•NO) generation but not ROS plays a major role in silibinin-induced autophagic and apoptotic death in human epidermoid carcinoma A431 cells. Free Radical Research 46:11, pages 1346-1360.
Read now
Simiao Fan, Yang Yu, Min Qi, Zhongdong Sun, Lihua Li, Guodong Yao, Shin-Ichi Tashiro, Satoshi Onodera & Takashi Ikejima. (2012) P53-mediated GSH depletion enhanced the cytotoxicity of NO in silibinin-treated human cervical carcinoma HeLa cells. Free Radical Research 46:9, pages 1082-1092.
Read now

Articles from other publishers (24)

Anns Mahboob, Degiri Kalana Lasanga Senevirathne, Pradipta Paul, Faisal Nabi, Rizwan Hasan Khan & Ali Chaari. (2023) An investigation into the potential action of polyphenols against human Islet Amyloid Polypeptide aggregation in type 2 diabetes. International Journal of Biological Macromolecules 225, pages 318-350.
Crossref
Carsten Esselun, Bastian Bruns, Stephanie Hagl, Rekha Grewal & Gunter P. Eckert. (2021) Impact of Silibinin A on Bioenergetics in PC12APPsw Cells and Mitochondrial Membrane Properties in Murine Brain Mitochondria. Antioxidants 10:10, pages 1520.
Crossref
Jinguo Shi, Yang Wang, Jianwen Chen, Yaoqiang Lao, Ping Huang, Liping Liao, Caibao Jiang, Xinhua Li, Jin Wen, Shujia Zhou & Jingxia Zhang. (2021) Synthesis and biological evaluation of 1,2,4-oxadiazole core derivatives as potential neuroprotectants against acute ischemic stroke. Neurochemistry International 148, pages 105103.
Crossref
Yan HU, Xu ZHANG, Fuzhi LIAN, Jun YANG & Xianrong XU. (2021) Combination of Lutein and DHA Alleviate H<sub>2</sub>O<sub>2</sub> Induced Cytotoxicity in PC12 Cells by Regulating the MAPK Pathway. Journal of Nutritional Science and Vitaminology 67:4, pages 234-242.
Crossref
Hardeep Singh Tuli, Sonam Mittal, Diwakar Aggarwal, Gaurav Parashar, Nidarshana Chaturvedi Parashar, Sushil Kumar Upadhyay, Tushar Singh Barwal, Aklank Jain, Ginpreet Kaur, Raj Savla, Katrin Sak, Manoj Kumar, Mehmet Varol, Ashif Iqubal & Anil Kumar Sharma. (2021) Path of Silibinin from diet to medicine: A dietary polyphenolic flavonoid having potential anti-cancer therapeutic significance. Seminars in Cancer Biology 73, pages 196-218.
Crossref
Lingling Si, Jianing Fu, Weiwei Liu, Toshihiko Hayashi, Yuheng Nie, Kazunori Mizuno, Shunji Hattori, Hitomi Fujisaki, Satoshi Onodera & Takashi Ikejima. (2019) Silibinin inhibits migration and invasion of breast cancer MDA-MB-231 cells through induction of mitochondrial fusion. Molecular and Cellular Biochemistry 463:1-2, pages 189-201.
Crossref
Carsten Esselun, Bastian Bruns, Stephanie Hagl, Rekha Grewal & Gunter P. Eckert. (2019) Differential Effects of Silibinin A on Mitochondrial Function in Neuronal PC12 and HepG2 Liver Cells. Oxidative Medicine and Cellular Longevity 2019, pages 1-10.
Crossref
Xia Zhao, Zhiwen Zeng, Uma Gaur, Jiankang Fang, Tangming Peng, Shuai Li & Wenhua Zheng. (2019) Metformin protects PC12 cells and hippocampal neurons from H 2 O 2 ‐induced oxidative damage through activation of AMPK pathway . Journal of Cellular Physiology 234:9, pages 16619-16629.
Crossref
Yunxia Li, Biao Yang, Jia-yu Bai, Shuyue Xia, Mingqing Mao, Xiaoyang Li, Nan Li & Lei Chen. (2019) The roles of synovial hyperplasia, angiogenesis and osteoclastogenesis in the protective effect of apigenin on collagen-induced arthritis. International Immunopharmacology 73, pages 362-369.
Crossref
Do Eun Rim, Hyung Jae Yoo, Jeong‐Hwa Lee, Oh‐Joo Kwon & Seong‐Whan Jeong. (2019) Role of GS28 in sodium nitroprusside‐induced cell death in cervical carcinoma cells. Journal of Biochemical and Molecular Toxicology 33:8.
Crossref
Bowen Wu, Miduo Tan, Weiliang Cai, Biao Wang, Peiheng He & Xiping Zhang. (2018) Arsenic trioxide induces autophagic cell death in osteosarcoma cells via the ROS-TFEB signaling pathway. Biochemical and Biophysical Research Communications 496:1, pages 167-175.
Crossref
Naying Chu, Guodong Yao, Yuan Liu, Maosheng Cheng & Takashi Ikejima. (2016) Newly synthesized bis-benzimidazole compound 8 induces apoptosis, autophagy and reactive oxygen species generation in HeLa cells. Bioorganic & Medicinal Chemistry Letters 26:17, pages 4367-4371.
Crossref
Wenhua Zheng, Cheong-Meng Chong, Haitao Wang, Xuanhe Zhou, Lang Zhang, Rikang Wang, Qian Meng, Philip Lazarovici & Jiankang Fang. (2016) Artemisinin conferred ERK mediated neuroprotection to PC12 cells and cortical neurons exposed to sodium nitroprusside-induced oxidative insult. Free Radical Biology and Medicine 97, pages 158-167.
Crossref
Sua In, Chang-Won Hong, Boyoung Choi, Bong-Geum Jang & Min-Ju Kim. (2015) Inhibition of Mitochondrial Clearance and Cu/Zn-SOD Activity Enhance 6-Hydroxydopamine-Induced Neuronal Apoptosis. Molecular Neurobiology 53:1, pages 777-791.
Crossref
Hai-Jian Wu, Jia-Li Pu, Paul. R. Krafft, Jian-Min Zhang & Sheng Chen. (2014) The Molecular Mechanisms Between Autophagy and Apoptosis: Potential Role in Central Nervous System Disorders. Cellular and Molecular Neurobiology 35:1, pages 85-99.
Crossref
Y. Hayashi, Y. Koga, X. Zhang, C. Peters, Y. Yanagawa, Z. Wu, T. Yokoyama & H. Nakanishi. (2014) Autophagy in superficial spinal dorsal horn accelerates the cathepsin B-dependent morphine antinociceptive tolerance. Neuroscience 275, pages 384-394.
Crossref
Taichi Kashiwagi, Hanxu Yan, Takeki Hamasaki, Tomoya Kinjo, Noboru Nakamichi, Kiichiro Teruya, Shigeru Kabayama & Sanetaka Shirahata. (2014) Electrochemically Reduced Water Protects Neural Cells from Oxidative Damage. Oxidative Medicine and Cellular Longevity 2014, pages 1-18.
Crossref
Xuanbin Wang, Yibin Feng, Ning Wang, Fan Cheung, Hor Yue Tan, Sen Zhong, Charlie Li & Seiichi Kobayashi. (2014) Chinese Medicines Induce Cell Death: The Molecular and Cellular Mechanisms for Cancer Therapy. BioMed Research International 2014, pages 1-14.
Crossref
Xinxin Yang, Xiaoyu Li, Liangxiang An, Bo Bai & Jing Chen. (2013) Silibinin induced the apoptosis of Hep-2 cells via oxidative stress and down-regulating survivin expression. European Archives of Oto-Rhino-Laryngology 270:8, pages 2289-2297.
Crossref
Linghe Zang, Hao He, Qian Xu, Yang Yu, Nan Zheng, Weiwei Liu, Toshihiko Hayashi, Shin-ichi Tashiro, Satoshi Onodera & Takashi Ikejima. (2013) Reactive oxygen species H2O2 and OH, but not O2− promote oridonin-induced phagocytosis of apoptotic cells by human histocytic lymphoma U937 cells. International Immunopharmacology 15:2, pages 414-423.
Crossref
Min Qi, Simiao Fan, Guodong Yao, Zhao Li, Haiyan Zhou, Shin-ichi Tashiro, Satoshi Onodera, Mingyu Xia & Takashi Ikejima. (2013) Pseudolaric Acid B^|^ndash;Induced Autophagy Contributes to Senescence via Enhancement of ROS Generation and Mitochondrial Dysfunction in Murine Fibrosarcoma L929 Cells. Journal of Pharmacological Sciences 121:3, pages 200-211.
Crossref
Svenja Nölting, Edwin Garcia, Ghassan Alusi, Alessio Giubellino, Karel Pacak, Márta Korbonits & Ashley B Grossman. (2012) Combined blockade of signalling pathways shows marked anti-tumour potential in phaeochromocytoma cell lines. Journal of Molecular Endocrinology 49:2, pages 79-96.
Crossref
Jia Wang, Guangyuan Chen, Hanlin Gong, Wei Huang, Dan Long & Wenfu Tang. (2012) Amelioration of Experimental Acute Pancreatitis with Dachengqi Decoction via Regulation of Necrosis-Apoptosis Switch in the Pancreatic Acinar Cell. PLoS ONE 7:7, pages e40160.
Crossref
Biao Cheng, Hao Gong, Xiaochao Li, Yue Sun, Xin Zhang, Hong Chen, Xinran Liu, Ling Zheng & Kun Huang. (2012) Silibinin inhibits the toxic aggregation of human islet amyloid polypeptide. Biochemical and Biophysical Research Communications 419:3, pages 495-499.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.