333
Views
39
CrossRef citations to date
0
Altmetric
Research Article

Roles of mitochondria-generated reactive oxygen species on X-ray-induced apoptosis in a human hepatocellular carcinoma cell line, HLE

, , , , , , , , , , , , , , , & show all
Pages 1029-1043 | Received 24 May 2012, Accepted 24 May 2012, Published online: 25 Jun 2012

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (7)

Ying Jie Zhou, Yun Tang, Si Jian Liu, Peng Hui Zeng, Li Qu, Qian Cheng Jing & Wen Jun Yin. (2023) Radiation-induced liver disease: beyond DNA damage. Cell Cycle 22:5, pages 506-526.
Read now
Jen-Yang Tang, Chih-Wen Shu, Chun-Lin Wang, Sheng-Chieh Wang, Meng-Yang Chang, Li-Ching Lin & Hsueh-Wei Chang. (2019) Sulfonyl chromen-4-ones (CHW09) shows an additive effect to inhibit cell growth of X-ray irradiated oral cancer cells, involving apoptosis and ROS generation. International Journal of Radiation Biology 95:9, pages 1226-1235.
Read now
Qing-Li Zhao, Hiroko Ito, Takashi Kondo, Takashi Uehara, Masayuki Ikeda, Hitoshi Abe, Jun-Ichi Saitoh, Kyo Noguchi, Michio Suzuki & Masayoshi Kurachi. (2019) Antipsychotic drugs scavenge radiation-induced hydroxyl radicals and intracellular ROS formation, and protect apoptosis in human lymphoma U937 cells. Free Radical Research 53:3, pages 304-312.
Read now
Kumiko Yamamoto, Yoshinori Ikenaka, Takahiro Ichise, Tomoki Bo, Mayumi Ishizuka, Hironobu Yasui, Wakako Hiraoka, Tohru Yamamori & Osamu Inanami. (2018) Evaluation of mitochondrial redox status and energy metabolism of X-irradiated HeLa cells by LC/UV, LC/MS/MS and ESR. Free Radical Research 52:6, pages 648-660.
Read now
Shubhankar Suman, Santosh Kumar, Albert J. Fornace Jr & Kamal Datta. (2018) The effect of carbon irradiation is associated with greater oxidative stress in mouse intestine and colon relative to γ-rays. Free Radical Research 52:5, pages 556-567.
Read now
T. Nakanishi-Ueda, H. J. Majima, K. Watanabe, T. Ueda, H. P. Indo, S. Suenaga, T. Hisamitsu, T. Ozawa, H. Yasuhara & R. Koide. (2013) Blue LED light exposure develops intracellular reactive oxygen species, lipid peroxidation, and subsequent cellular injuries in cultured bovine retinal pigment epithelial cells. Free Radical Research 47:10, pages 774-780.
Read now
Hideyuki J. Majima & Shinya Toyokuni. (2012) Mitochondria and free radical studies on health, disease and pollution. Free Radical Research 46:8, pages 925-926.
Read now

Articles from other publishers (32)

Richard Cornette, Hiroko P. Indo, Ken-ichi Iwata, Yuka Hagiwara-Komoda, Yuichi Nakahara, Oleg Gusev, Takahiro Kikawada, Takashi Okuda & Hideyuki J. Majima. (2023) Oxidative stress is an essential factor for the induction of anhydrobiosis in the desiccation-tolerant midge, Polypedilum vanderplanki (Diptera, Chironomidae). Mitochondrion 73, pages 84-94.
Crossref
Qiyang Li, Shangzu Zhang, Gengqiang Yang, Xin Wang, Fuxian Liu, Yangyang Li, Yan Chen, Ting Zhou, Dingxiong Xie, Yongqi Liu & Liying Zhang. (2023) Energy metabolism: A critical target of cardiovascular injury. Biomedicine & Pharmacotherapy 165, pages 115271.
Crossref
Megumi Ueno, Raj Kumar Parajuli, Hiromu Ito, Megumi Iiyama, Saaya Suzuki, Ken-ichiro Matsumoto, Ikuo Nakanishi, Ichio Aoki & Akira Sumiyoshi. (2023) Effects of X-ray irradiation on the redox status of mouse colorectal tissues. Advances in Redox Research 8, pages 100067.
Crossref
Kazuo Tomita, Hiroko P. Indo, Tomoaki Sato, Jitbanjong Tangpong & Hideyuki J. Majima. (2023) Development of a sensitive double TaqMan Probe-based qPCR Angle-Degree method to detect mutation frequencies. Mitochondrion 70, pages 1-7.
Crossref
Hiroko P. Indo, Daisuke Masuda, Sompong Sriburee, Hiromu Ito, Ikuo Nakanishi, Ken-ichiro Matsumoto, Samlee Mankhetkorn, Moragot Chatatikun, Sirirat Surinkaew, Lunla Udomwech, Fumitaka Kawakami, Takafumi Ichikawa, Hirofumi Matsui, Jitbanjong Tangpong & Hideyuki J. Majima. (2023) Evidence of Nrf2/Keap1 Signaling Regulation by Mitochodria-Generated Reactive Oxygen Species in RGK1 Cells. Biomolecules 13:3, pages 445.
Crossref
Megumi Ueno, Sayaka Shibata, Ikuo Nakanishi, Ichio Aoki, Ken-ichi Yamada & Ken-ichiro Matsumoto. (2023) Effects of selenium deficiency on biological results of X-ray and carbon-ion beam irradiation in mice. Journal of Clinical Biochemistry and Nutrition 72:2, pages 107-116.
Crossref
Keisuke S. Iwamoto, Robert E. Sandstrom, Mark Bryan, Yue Liu, S. Robin Elgart, Ke Sheng, Michael L. Steinberg, William H. McBride & Daniel A. Low. (2021) Weak Magnetic Fields Enhance the Efficacy of Radiation Therapy. Advances in Radiation Oncology 6:3, pages 100645.
Crossref
Hiroko P. Indo, Hiromu Ito, Keiichi Nakagawa, Luksana Chaiswing & Hideyuki J. Majima. (2021) Translocation of HSP47 and generation of mitochondrial reactive oxygen species in human neuroblastoma SK-N-SH cells following electron and X-ray irradiation. Archives of Biochemistry and Biophysics 703, pages 108853.
Crossref
Hiromu Ito. (2021) Peroxynitrite Production Induced by LPS and X-ray Treatment Enhances Cellular Incorporation of Porphyrin in Mouse RAW264 Macrophages. Applied Sciences 11:8, pages 3503.
Crossref
Megumi Ueno, Takashi Shimokawa, Emiko Sekine-Suzuki, Minako Nyui, Ikuo Nakanishi & Ken-ichiro Matsumoto. (2021) Preparation of an experimental mouse model lacking selenium-dependent glutathione peroxidase activities by feeding a selenium-deficient diet. Journal of Clinical Biochemistry and Nutrition 68:2, pages 123-130.
Crossref
Hiromu Ito, Hiromi Kurokawa & Hirofumi Matsui. (2021) Mitochondrial reactive oxygen species and heme, non-heme iron metabolism. Archives of Biochemistry and Biophysics 700, pages 108695.
Crossref
Hiroshi Maezawa, Hiroko P Indo, Noriko Usami, Hideyuki J Majima, Hiromu Ito, Ken Ohnishi & Katsumi Kobayashi. (2020) Enhancement of membrane lipid peroxidation in lung cancer cells irradiated with monoenergetic X-rays at the K-shell resonance absorption peak of phosphorus. Journal of Radiation Research 61:2, pages 237-242.
Crossref
Mizuki Nakamura, Toshihide Yamasaki, Megumi Ueno, Sayaka Shibata, Yoshikazu Ozawa, Tadashi Kamada, Ikuo Nakanishi, Ken-ichi Yamada, Ichio Aoki & Ken-ichiro Matsumoto. (2019) Radiation-induced redox alteration in the mouse brain. Free Radical Biology and Medicine 143, pages 412-421.
Crossref
Elke Decrock, Delphine Hoorelbeke, Raghda Ramadan, Tinneke Delvaeye, Marijke De Bock, Nan Wang, Dmitri V Krysko, Sarah Baatout, Geert Bultynck, An Aerts, Mathieu Vinken & Luc Leybaert. (2017) Calcium, oxidative stress and connexin channels, a harmonious orchestra directing the response to radiotherapy treatment?. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1864:6, pages 1099-1120.
Crossref
Hiromu Ito, Hiromi Kurokawa, Aki Hirayama, Hiroko P. Indo, Hideyuki J. Majima & Hirofumi Matsui. (2017) Cancer cell-specific mitochondrial reactive oxygen species promote non-heme iron uptake and enhance the proliferation of gastric epithelial cancer cell. Journal of Clinical Biochemistry and Nutrition 61:3, pages 183-188.
Crossref
Souparno Bhattacharya & Aroumougame Asaithamby. (2016) Ionizing radiation and heart risks. Seminars in Cell & Developmental Biology 58, pages 14-25.
Crossref
Hideyuki J. Majima, Hiroko P. Indo, Ikuo Nakanishi, Shigeaki Suenaga, Ken-ichiro Matsumoto, Hirofumi Matsui, Yukiko Minamiyama, Hiroshi Ichikawa, Hsiu-Chuan Yen, Clare L. Hawkins, Michael J. Davies, Toshihiko Ozawa & Daret K. St Clair. (2016) Chasing great paths of Helmut Sies “Oxidative Stress”. Archives of Biochemistry and Biophysics 595, pages 54-60.
Crossref
Rui Liu, Ming Fan, Demet Candas, Lili Qin, Xiaodi Zhang, Angela Eldridge, June X. Zou, Tieqiao Zhang, Shuaib Juma, Cuihong Jin, Robert F. Li, Julian Perks, Lun-Quan Sun, Andrew T.M. Vaughan, Chun-Xu Hai, David R. Gius & Jian Jian Li. (2015) CDK1-Mediated SIRT3 Activation Enhances Mitochondrial Function and Tumor Radioresistance. Molecular Cancer Therapeutics 14:9, pages 2090-2102.
Crossref
Chinami Matsumoto, Emiko Sekine-Suzuki, Minako Nyui, Megumi Ueno, Ikuo Nakanishi, Yuji Omiya, Masato Fukutake, Yoshio Kase & Ken-ichiro Matsumoto. (2015) Analysis of the antioxidative function of the radioprotective Japanese traditional (Kampo) medicine, hangeshashinto, in an aqueous phase. Journal of Radiation Research 56:4, pages 669-677.
Crossref
E. K. Fetisova, M. M. Antoschina, V. D. Cherepanynets, D. S. Izumov, I. I. Kireev, R. I. Kireev, K. G. Lyamzaev, N. I. Riabchenko, B. V. Chernyak & V. P. Skulachev. (2015) Mitochondria-targeted antioxidant SkQR1 selectively protects MDR-negative cells from ionizing radiation. Cell and Tissue Biology 9:2, pages 87-95.
Crossref
Hiroko P. Indo, Hsiu-Chuan Yen, Ikuo Nakanishi, Ken-ichiro Matsumoto, Masato Tamura, Yumiko Nagano, Hirofumi Matsui, Oleg Gusev, Richard Cornette, Takashi Okuda, Yukiko Minamiyama, Hiroshi Ichikawa, Shigeaki Suenaga, Misato Oki, Tsuyoshi Sato, Toshihiko Ozawa, Daret K. St. Clair & Hideyuki J. Majima. (2015) A mitochondrial superoxide theory for oxidative stress diseases and aging. Journal of Clinical Biochemistry and Nutrition 56:1, pages 1-7.
Crossref
Hirohito Tsubouchi, Akihiko Ohshige & Hirofumi Uto. (2015) Liver and oxidative stress. Kanzo 56:7, pages 313-323.
Crossref
Elena K. Fetisova, Margarita M. Antoschina, Varvara D. Cherepanynets, Denis S. Izumov, Igor I. Kireev, Roman I. Kireev, Konstantin G. Lyamzaev, Nikolay I. Riabchenko, Boris V. Chernyak & Vladimir P. Skulachev. (2015) Radioprotective Effects of Mitochondria-Targeted Antioxidant SkQR1. Radiation Research 183:1, pages 64-71.
Crossref
Masato Tamura & Hirofumi Matsui. 2015. Hyper Bio Assembler for 3D Cellular Systems. Hyper Bio Assembler for 3D Cellular Systems 305 315 .
Boxing Su, Bentao Shi, Yuan Tang, Zhongqiang Guo, Xi Yu, Xinyong He, Xuesong Li, Xianshu Gao & Liqun Zhou. (2015) HMGN5 knockdown sensitizes prostate cancer cells to ionizing radiation. The Prostate 75:1, pages 33-44.
Crossref
BI-YUN ZHENG, XUE-FEN FANG, LAI-YU ZOU, YUE-HONG HUANG, ZHI-XIN CHEN, DAN LI, LIN-YING ZHOU, HAO CHEN & XIAO-ZHONG WANG. (2014) The co-localization of HBx and COXIII upregulates COX-2 promoting HepG2 cell growth. International Journal of Oncology 45:3, pages 1143-1150.
Crossref
N. Nishida, H. Yasui, M. Nagane, T. Yamamori & O. Inanami. (2014) 3-Methyl pyruvate enhances radiosensitivity through increasing mitochondria-derived reactive oxygen species in tumor cell lines. Journal of Radiation Research 55:3, pages 455-463.
Crossref
Masato Tamura, Hirofumi Matsui, Tsutomu Tomita, Hisato Sadakata, Hiroko P. Indo, Hideyuki J. Majima, Tsuyoshi Kaneko & Ichinosuke Hyodo. (2014) Mitochondrial reactive oxygen species accelerate gastric cancer cell invasion. Journal of Clinical Biochemistry and Nutrition 54:1, pages 12-17.
Crossref
Winnie Wai-Ying Kam & Richard B. Banati. (2013) Effects of ionizing radiation on mitochondria. Free Radical Biology and Medicine 65, pages 607-619.
Crossref
Winnie Wai-Ying Kam, Aimee L. McNamara, Vanessa Lake, Connie Banos, Justin B. Davies, Zdenka Kuncic & Richard B. Banati. (2013) Predicted ionisation in mitochondria and observed acute changes in the mitochondrial transcriptome after gamma irradiation: A Monte Carlo simulation and quantitative PCR study. Mitochondrion 13:6, pages 736-742.
Crossref
Winnie Kam, Vanessa Lake, Connie Banos, Justin Davies & Richard Banati. (2013) Apparent Polyploidization after Gamma Irradiation: Pitfalls in the Use of Quantitative Polymerase Chain Reaction (qPCR) for the Estimation of Mitochondrial and Nuclear DNA Gene Copy Numbers. International Journal of Molecular Sciences 14:6, pages 11544-11559.
Crossref
Hiroko P. Indo, Ikuo Nakanishi, Kei Ohkubo, Hsiu-Chuan Yen, Minako Nyui, Sushma Manda, Ken-ichiro Matsumoto, Kiyoshi Fukuhara, Kazunori Anzai, Nobuo Ikota, Hirofumi Matsui, Yukiko Minamiyama, Akira Nakajima, Hiroshi Ichikawa, Shunichi Fukuzumi, Toshihiko Ozawa, Chiaki Mukai & Hideyuki J. Majima. (2013) Comparison of in vivo and in vitro antioxidative parameters for eleven food factors. RSC Advances 3:14, pages 4535.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.