667
Views
58
CrossRef citations to date
0
Altmetric
Review Article

Exercise-induced improvements in myocardial antioxidant capacity: the antioxidant players and cardioprotection

, , , &
Pages 43-51 | Received 17 May 2013, Accepted 11 Jul 2013, Published online: 07 Oct 2013

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (3)

Dawei Wang, Hongyan Cao, Xu Wang, Jinchun Wang, Manli Wang, Jian Zhang & Lin Wang. (2021) RETRACTED ARTICLE: SIRT1 is Required for Exercise-Induced Beneficial Effects on Myocardial Ischemia/Reperfusion Injury. Journal of Inflammation Research 14, pages 1283-1296.
Read now
W. Ziolkowski, D. J. Flis, M. Halon, D. M. S. Vadhana, R. A. Olek, M. Carloni, J. Antosiewicz, J. J. Kaczor & R. Gabbianelli. (2015) Prolonged swimming promotes cellular oxidative stress and p66Shc phosphorylation, but does not induce oxidative stress in mitochondria in the rat heart. Free Radical Research 49:1, pages 7-16.
Read now
J. Vina & M. C. Gomez-Cabrera. (2014) FORUM ISSUE: “Free Radicals and Physical Exercise”. Free Radical Research 48:1, pages 1-2.
Read now

Articles from other publishers (55)

Dae Yun Seo, Jun-Hyun Bae, Xinxing Li & Jin Han. (2023) Exercise Training and Cardiovascular Health: Mechanisms, Benefits, and Therapeutic Implications in Cardiovascular Disease. CardioMetabolic Syndrome Journal 3:2, pages 123.
Crossref
Bo Wang, Lin Gan, Yuzhi Deng, Shuoji Zhu, Ge Li, Moussa Ide Nasser, Nanbo Liu & Ping Zhu. (2022) Cardiovascular Disease and Exercise: From Molecular Mechanisms to Clinical Applications. Journal of Clinical Medicine 11:24, pages 7511.
Crossref
Chanisa Thonusin, Patcharapong Pantiya, Natticha Sumneang, Titikorn Chunchai, Wichwara Nawara, Busarin Arunsak, Natthaphat Siri-Angkul, Sirawit Sriwichaiin, Siriporn C. Chattipakorn & Nipon Chattipakorn. (2022) Effectiveness of high cardiorespiratory fitness in cardiometabolic protection in prediabetic rats. Molecular Medicine 28:1.
Crossref
Mary Audrey D. Viloria, Qing Li, Wang Lu, Nguyen Thanh Nhu, Yijie Liu, Zhen-Yang Cui, Yu-Jung Cheng & Shin-Da Lee. (2022) Effect of exercise training on cardiac mitochondrial respiration, biogenesis, dynamics, and mitophagy in ischemic heart disease. Frontiers in Cardiovascular Medicine 9.
Crossref
Huihua Chen, Chen Chen, Michail Spanos, Guoping Li, Rong Lu, Yihua Bei & Junjie Xiao. (2022) Exercise training maintains cardiovascular health: signaling pathways involved and potential therapeutics. Signal Transduction and Targeted Therapy 7:1.
Crossref
Leonardo Matta, Caroline Coelho de Faria, Dahienne F. De Oliveira, Iris Soares Andrade, Niedson Correia Lima-Junior, Bianca Martins Gregório, Cristina Maeda Takiya, Andrea Claudia Freitas Ferreira, José Hamilton M. Nascimento, Denise Pires de Carvalho, Alexander Bartelt, Leonardo Maciel & Rodrigo Soares Fortunato. (2022) Exercise Improves Redox Homeostasis and Mitochondrial Function in White Adipose Tissue. Antioxidants 11:9, pages 1689.
Crossref
H. MaheriniaM. PeeriM.A. AzarbayjaniM. Delfan. (2022) Aerobic exercise training combined with probiotic supplement improves antioxidant defence of cardiomyocytes by regulating Nrf2 and caspase3 gene expression in type 2 diabetic rats. Comparative Exercise Physiology 18:3, pages 255-263.
Crossref
Arash Heidari, Sara Momtazmanesh & Nima Rezaei. 2022.
David Weissman & Christoph Maack. (2021) Redox signaling in heart failure and therapeutic implications. Free Radical Biology and Medicine 171, pages 345-364.
Crossref
Alessandro Patti, Laura Merlo, Marco Ambrosetti & Patrizio Sarto. (2021) Exercise-Based Cardiac Rehabilitation Programs in Heart Failure Patients. Heart Failure Clinics 17:2, pages 263-271.
Crossref
Morteza Rouhani. (2021) Evaluation of structural properties and antioxidant capacity of Proxison: A DFT investigation. Computational and Theoretical Chemistry 1195, pages 113096.
Crossref
David E. Lee, Jacob L. Brown, Megan E. Rosa‐Caldwell, Richard A. Perry, Lemuel A. Brown, Wesley S. Haynie, Tyrone A. Washington, Michael P. Wiggs, Narasimhan Rajaram & Nicholas P. Greene. (2020) Cancer‐induced cardiac atrophy adversely affects myocardial redox state and mitochondrial oxidative characteristics. JCSM Rapid Communications 4:1, pages 3-15.
Crossref
Márton Richárd Szabó, Márton Pipicz, Tamás Csont & Csaba Csonka. (2020) Modulatory Effect of Myokines on Reactive Oxygen Species in Ischemia/Reperfusion. International Journal of Molecular Sciences 21:24, pages 9382.
Crossref
Andrés J. Medina, Alejandro M. Ibáñez, Leandro A. Diaz-Zegarra, Enrique L. Portiansky, Paula G. Blanco, Erica V. Pereyra, Verónica C. de Giusti, Ernesto A. Aiello, Alejandra M. Yeves & Irene L. Ennis. (2020) Cardiac up-regulation of NBCe1 emerges as a beneficial consequence of voluntary wheel running in mice. Archives of Biochemistry and Biophysics 694, pages 108600.
Crossref
Qiaoqin Liang, Mengxin Cai, Jiaqi Zhang, Wei Song, Wanyu Zhu, Lei Xi & Zhenjun Tian. (2020) Role of Muscle-Specific Histone Methyltransferase (Smyd1) in Exercise-Induced Cardioprotection against Pathological Remodeling after Myocardial Infarction. International Journal of Molecular Sciences 21:19, pages 7010.
Crossref
A. Calderón, O.F. Araneda, L. Terreros & G. Cavada. (2020) NADAR 2,5-KM INDOOR DISMINUYE EL NITRITO Y pH EN AIRE ESPIRADO CONDENSADO. Revista Internacional de Medicina y Ciencias de la Actividad Física y del Deporte 20:78, pages 197-210.
Crossref
David C. Poole, Steven W. Copp, Trenton D. Colburn, Jesse C. Craig, David L. Allen, Michael Sturek, Donal S. O’Leary, Irving H. Zucker & Timothy I. Musch. (2020) Guidelines for animal exercise and training protocols for cardiovascular studies. American Journal of Physiology-Heart and Circulatory Physiology 318:5, pages H1100-H1138.
Crossref
Doria Boulghobra, Florence Coste, Bernard Geny & Cyril Reboul. (2020) Exercise training protects the heart against ischemia-reperfusion injury: A central role for mitochondria?. Free Radical Biology and Medicine 152, pages 395-410.
Crossref
Najmeh Barghi, Effat Bambaeichi, Mostafa Rezaei-Tavirani & Neda Khaledi. (2020) Aerobic exercises induce antioxidant pathways activation in rats. International Journal of Preventive Medicine 11:1, pages 144.
Crossref
ChidiebereEmmanuel Okechukwu. (2020) Role of aerobic exercise in mitigating cancer treatment-induced cardiovascular toxicity. Cancer Research, Statistics, and Treatment 3:3, pages 636.
Crossref
Nurul Paramita, Imma Fatayati, Syarifah Dewi, Dewi Irawati Soeria Santoso, Trinovita Andraini, Neng Tine Kartinah, Ermita Isfandiary Ibrahim Ilyas, Mariyal Qibtiyah & Sri Yunita. Effect of Hibiscus sabdariffa Linn. on oxidative stress in cardiac tissue of overtrained rat: Study on malonildialdehid (MDA), superoxide dismutase (SOD), glutathione (GSH), and NADPH oxidase (Nox2). Effect of Hibiscus sabdariffa Linn. on oxidative stress in cardiac tissue of overtrained rat: Study on malonildialdehid (MDA), superoxide dismutase (SOD), glutathione (GSH), and NADPH oxidase (Nox2).
Dandan Jia, Lu Hou, Yongzhi Lv, Lei Xi & Zhenjun Tian. (2019) Postinfarction exercise training alleviates cardiac dysfunction and adverse remodeling via mitochondrial biogenesis and SIRT1/PGC‐1α/PI3K/Akt signaling. Journal of Cellular Physiology 234:12, pages 23705-23718.
Crossref
Caroline D. Veloso, Getachew D. Belew, Luciana L. Ferreira, Luís F. Grilo, John G. Jones, Piero Portincasa, Vilma A. Sardão & Paulo J. Oliveira. (2019) A Mitochondrial Approach to Cardiovascular Risk and Disease. Current Pharmaceutical Design 25:29, pages 3175-3194.
Crossref
Alyson Sujkowski, Adam N. Spierer, Thiviya Rajagopalan, Brian Bazzell, Maryam Safdar, Dinko Imsirovic, Robert Arking, David M. Rand & Robert Wessells. (2019) Mito-nuclear interactions modify Drosophila exercise performance. Mitochondrion 47, pages 188-205.
Crossref
Vikram Shettigar & Mark T. Ziolo. 2019. Modulation of Oxidative Stress in Heart Disease. Modulation of Oxidative Stress in Heart Disease 533 553 .
Matthew Hancock, Anne D Hafstad, Adam A Nabeebaccus, Norman Catibog, Angela Logan, Ioannis Smyrnias, Synne S Hansen, Johanna Lanner, Katrin Schröder, Michael P Murphy, Ajay M Shah & Min Zhang. (2018) Myocardial NADPH oxidase-4 regulates the physiological response to acute exercise. eLife 7.
Crossref
Erin J. Howden, André La Gerche, Jane F. Arthur, Julie R. McMullen, Garry L. Jennings, David W. Dunstan, Neville Owen, Sharon Avery & Bronwyn A. Kingwell. (2018) Standing up to the cardiometabolic consequences of hematological cancers. Blood Reviews 32:5, pages 349-360.
Crossref
Dajun Zhao, Yang Sun, Yanzhen Tan, Zhengbin Zhang, Zuoxu Hou, Chao Gao, Pan Feng, Xing Zhang, Wei Yi & Feng Gao. (2018) Short-Duration Swimming Exercise after Myocardial Infarction Attenuates Cardiac Dysfunction and Regulates Mitochondrial Quality Control in Aged Mice. Oxidative Medicine and Cellular Longevity 2018, pages 1-16.
Crossref
Bianca C. Bernardo, Jenny Y. Y. Ooi, Kate L. Weeks, Natalie L. Patterson & Julie R. McMullen. (2018) Understanding Key Mechanisms of Exercise-Induced Cardiac Protection to Mitigate Disease: Current Knowledge and Emerging Concepts. Physiological Reviews 98:1, pages 419-475.
Crossref
Ehtramolsadat Sahafi, Maghsoud Peeri, Mir-Jamal Hosseini & Mohammad Ali Azarbyjani. (2018) Cardiac oxidative stress following maternal separation stress was mitigated following adolescent voluntary exercise in adult male rat. Physiology & Behavior 183, pages 39-45.
Crossref
Traci L. Parry, Joseph W. Starnes, Sara K. O’Neal, James R. Bain, Michael J. Muehlbauer, Aubree Honcoop, Amro Ilaiwy, Peter Christopher, Cam Patterson & Monte S. Willis. (2017) Untargeted metabolomics analysis of ischemia–reperfusion-injured hearts ex vivo from sedentary and exercise-trained rats. Metabolomics 14:1.
Crossref
Jorge Beleza, David Rizo-Roca, António Ascensão & José Magalhães. 2018. Mitochondrial Biology and Experimental Therapeutics. Mitochondrial Biology and Experimental Therapeutics 379 406 .
Scott K. Powers. (2017) Exercise: Teaching myocytes new tricks. Journal of Applied Physiology 123:2, pages 460-472.
Crossref
Petra Alánová, Anna Chytilová, Jan Neckář, Jaroslav Hrdlička, Petra Míčová, Kristýna Holzerová, Markéta Hlaváčková, Kristýna Macháčková, František Papoušek, Jana Vašinová, Daniel Benák, Olga Nováková & František Kolář. (2017) Myocardial ischemic tolerance in rats subjected to endurance exercise training during adaptation to chronic hypoxia. Journal of Applied Physiology 122:6, pages 1452-1461.
Crossref
Kathleen M. Sturgeon, Lorraine T. Dean, Mariane Heroux, Jessica Kane, Toni Bauer, Erica Palmer, Jin Long, Shannon Lynch, Linda Jacobs, David B. Sarwer, Mary B. Leonard & Kathryn Schmitz. (2016) Commercially available lifestyle modification program: randomized controlled trial addressing heart and bone health in BRCA1/2+ breast cancer survivors after risk-reducing salpingo-oophorectomy. Journal of Cancer Survivorship 11:2, pages 246-255.
Crossref
Cyril Reboul, Julien Boissière, Lucas André, Gregory Meyer, Patrice Bideaux, Gilles Fouret, Christine Feillet-Coudray, Philippe Obert, Alain Lacampagne, Jérôme Thireau, Olivier Cazorla & Sylvain Richard. (2017) Carbon monoxide pollution aggravates ischemic heart failure through oxidative stress pathway. Scientific Reports 7:1.
Crossref
Juliana Pereira Borges, Guilherme de Oliveira França, Mariana Delgado Cruz, Rômulo Lanza, Alessandro Rodrigues do Nascimento & Marcos Adriano Lessa. (2017) Aerobic exercise training induces superior cardioprotection following myocardial ischemia reperfusion injury than a single aerobic exercise session in rats. Motriz: Revista de Educação Física 23:spe.
Crossref
Bianca C. Bernardo & Julie R. McMullen. (2016) Molecular Aspects of Exercise-induced Cardiac Remodeling. Cardiology Clinics 34:4, pages 515-530.
Crossref
Sergej M. Ostojic. (2016) Exercise-induced mitochondrial dysfunction: a myth or reality?. Clinical Science 130:16, pages 1407-1416.
Crossref
Verônica B. Brito, Leopoldo V.M. Nascimento, Ramiro B. Nunes, Dinara J. Moura, Pedro Dal Lago & Jenifer Saffi. (2016) Exercise during pregnancy decreases doxorubicin-induced cardiotoxic effects on neonatal hearts. Toxicology 368-369, pages 46-57.
Crossref
D. STANOJEVIC, V. JAKOVLJEVIC, N. BARUDZIC, V. ZIVKOVIC, I. SREJOVIC, K. PAREZANOVIC ILIC, D. CUBRILO, Z. AHMETOVIC, D. PERIC, M. ROSIC, D. RADOVANOVIC & D. DJORDJEVIC. (2016) Overtraining Does Not Induce Oxidative Stress and Inflammation in Blood and Heart of Rats. Physiological Research, pages 81-90.
Crossref
Juan Wang, Lirong Teng, Yange Liu, Wenji Hu, Wenqi Chen, Xi Hu, Yingwu Wang & Di Wang. (2016) Studies on the Antidiabetic and Antinephritic Activities of Paecilomyces hepiali Water Extract in Diet-Streptozotocin-Induced Diabetic Sprague Dawley Rats . Journal of Diabetes Research 2016, pages 1-10.
Crossref
Jingjing Song, Yingwu Wang, Chungang Liu, Yan Huang, Liying He, Xueying Cai, Jiahui Lu, Yan Liu & Di Wang. (2016) Cordyceps militaris fruit body extract ameliorates membranous glomerulonephritis by attenuating oxidative stress and renal inflammation via the NF-κB pathway. Food & Function 7:4, pages 2006-2015.
Crossref
Laura M. Reyes, Raven Kirschenman, Anita Quon, Jude S. Morton, Amin Shah & Sandra T. Davidge. (2015) Aerobic exercise training reduces cardiac function in adult male offspring exposed to prenatal hypoxia. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 309:5, pages R489-R498.
Crossref
Tiago FernandesValério G. BaraúnaCarlos E. Negrão, M. Ian Phillips & Edilamar M. Oliveira. (2015) Aerobic exercise training promotes physiological cardiac remodeling involving a set of microRNAs. American Journal of Physiology-Heart and Circulatory Physiology 309:4, pages H543-H552.
Crossref
Eun-Jung Kim & Sujin Hwang. (2015) Effects of aerobic exercise on antioxidants in rat models with cardiomyopathy. Physical Therapy Rehabilitation Science 4:1, pages 17-21.
Crossref
Graham Ripley McGinnisChristopher BallmannBridget PetersGayani Nanayakkara, Michael Roberts, Rajesh Amin & John C. Quindry. (2015) Interleukin-6 mediates exercise preconditioning against myocardial ischemia reperfusion injury. American Journal of Physiology-Heart and Circulatory Physiology 308:11, pages H1423-H1433.
Crossref
J. LundA. D. HafstadN. T. BoardmanL. RossvollN. P. Rolim, M. S. Ahmed, G. Florholmen, H. Attramadal, U. Wisløff, T. S. LarsenE. Aasum. (2015) Exercise training promotes cardioprotection through oxygen-sparing action in high fat-fed mice. American Journal of Physiology-Heart and Circulatory Physiology 308:8, pages H823-H829.
Crossref
Lindsey E. Miller, Graham R. McGinnis, Bridget A. Peters, Christopher G. Ballmann, Gayani Nanayakkara, Rajesh Amin & John C. Quindry. (2015) Involvement of the δ-opioid receptor in exercise-induced cardioprotection. Experimental Physiology 100:4, pages 410-421.
Crossref
Yi Ju Hsu, Chien Chao Chiu, Yen Peng Li, Wen Ching Huang, Yen Te Huang, Chi Chang Huang & Hsiao Li Chuang. (2015) Effect of Intestinal Microbiota on Exercise Performance in Mice. Journal of Strength and Conditioning Research 29:2, pages 552-558.
Crossref
Jingjing Song, Yingwu Wang, Meiyu Teng, Guangsheng Cai, Hongkai Xu, Hanxiao Guo, Yang Liu, Di Wang & Lesheng Teng. (2015) Studies on the Antifatigue Activities of Cordyceps militaris Fruit Body Extract in Mouse Model . Evidence-Based Complementary and Alternative Medicine 2015, pages 1-15.
Crossref
Rita Ferreira, Daniel Moreira-Gonçalves, Ana Lúcia Azevedo, José Alberto Duarte, Francisco Amado & Rui Vitorino. (2014) Unraveling the exercise-related proteome signature in heart. Basic Research in Cardiology 110:1.
Crossref
Chi-Ting Horng, Jon-Kway Huang, Hui-Yun Wang, Chi-Chang Huang & Fu-An Chen. (2014) Antioxidant and Antifatigue Activities of Polygonatum Alte-lobatum Hayata Rhizomes in Rats. Nutrients 6:11, pages 5327-5337.
Crossref
Juliana P. Borges, Karine S. Verdoorn, Anissa Daliry, Scott K. Powers, Victor H. Ortenzi, Rodrigo S. Fortunato, Eduardo Tibiriçá & Marcos Adriano Lessa. (2014) Delta Opioid Receptors: The Link between Exercise and Cardioprotection. PLoS ONE 9:11, pages e113541.
Crossref
Simao Xu, Weichun Liu & Minhua Li. (2014) Effects of mRNA, Protein Expression and Activity for Myocardial SOD2 by a Single Bout of or Long-Term Strenuous Endurance Exercise in Rats. Chinese Medicine 05:04, pages 251-258.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.