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Original Article

An Aromatic Hydroxylation Assay for Hydroxyl Radicals Utilizing High-Performance Liquid Chromatography (HPLC). Use to Investigate the Effect of Edta on the Fenton Reaction

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Pages 243-250 | Received 26 Jul 1985, Published online: 07 Jul 2009

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M. J. Zhao, L. Jung, C. Tanielian & R. Mechin. (1994) Kinetics of the Competitive Degradation of Deoxyribose and other Biomolecules by Hydroxyl Radicals Produced by the Fenton Reaction. Free Radical Research 20:6, pages 345-363.
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Okezie I. Aruoma, Patricia J. Evans, Harparkash Kaur, Leslie Sutcliffe & Barry Halliwell. (1990) An Evaluation of the Antioxidant and Potential Pro-Oxidant Properties of Food Additives and the Trolox C., Vitamin E and Probucol. Free Radical Research Communications 10:3, pages 143-157.
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Barry Halliwell. (1990) How to Characterize a Biological Antioxidant. Free Radical Research Communications 9:1, pages 1-32.
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Martin Grootveld & Reetu Jain. (1989) Recent Advances in the Development of a Diagnostic Test for Irradiated Foodstuffs. Free Radical Research Communications 6:5, pages 271-292.
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Okezie I. Aruoma & Barry Halliwell. (1988) The iron-binding and hydroxyl radical scavenging action of anti-inflammatory drugs. Xenobiotica 18:4, pages 459-470.
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Martin Grootveld, Barry Halliwell & Christopher P. Moorhouse. (1987) Action of Uric Acid, Allopurinol and Oxypurinol on the Myeloperoxidase-Derived Oxidant Hypochlorous Acid. Free Radical Research Communications 4:2, pages 69-76.
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Horst Weber, Andreas Grzesiok, Hans‐Gert Korth & Reiner Sustmann. (2006) Zur Reaktion von 2,2‐Diphenyl‐1,2‐dihydrochinolin‐Nitroxid‐Radikalen mit dem NO‐Donator SIN‐1 (3‐Morpholinosydnonimin). Archiv der Pharmazie 327:12, pages 789-792.
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Martin Grootveld, Reetu Jain, Andrew W.D. Claxson, Declan Naughton & David R. Blake. (1990) The detection of irradiated foodstuffs. Trends in Food Science & Technology 1, pages 7-14.
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John M.C. Gutteridge, Imre Zs.-Nagy, Lindsay Maidt & Robert A. Floyd. (1990) ADP-iron as a fenton reactant: Radical reactions detected by spin trapping, hydrogen abstraction, and aromatic hydroxylation. Archives of Biochemistry and Biophysics 277:2, pages 422-428.
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. (1990) Review. Clinical Chemistry and Laboratory Medicine 28:9.
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PHILIP AISEN, GERALD COHEN & JAE O. KANG. 1990. Transition Metal Toxicity. Transition Metal Toxicity 1 46 .
Barry Halliwell & John M.C. Gutteridge. 1990. Oxygen Radicals in Biological Systems Part B: Oxygen Radicals and Antioxidants. Oxygen Radicals in Biological Systems Part B: Oxygen Radicals and Antioxidants 1 85 .
Miranda J. Laughton, Barry Halliwell, Patricia J. Evans, J. Robin & S. Hoult. (1989) Antioxidant and pro-oxidant actions of the plant phenolics quercetin, gossypol and myricetin. Biochemical Pharmacology 38:17, pages 2859-2865.
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John M.C. Gutteridge & Barry Halliwell. (1989) 1 Iron toxicity and oxygen radicals. Baillière's Clinical Haematology 2:2, pages 195-256.
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Martin Grootveld & Reetu Jain. (1989) Methods for the detection of irradiated foodstuffs: Aromatic hydroxylation and degradation of polyunsaturated fatty acids. International Journal of Radiation Applications and Instrumentation. Part C. Radiation Physics and Chemistry 34:6, pages 925-934.
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Harry C. Sutton & Christine C. Winterbourn. (1989) On the participation of higher oxidation states of iron and copper in fenton reactions. Free Radical Biology and Medicine 6:1, pages 53-60.
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William A. Pryor. (1989) On the detection of lipid hydroperoxides in biological samples. Free Radical Biology and Medicine 7:2, pages 177-178.
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Alain Puppo & Barry Halliwell. (1989) On the reaction of plant ferredoxins with hydrogen peroxide. What reactive oxidants are generated?. Phytochemistry 28:12, pages 3265-3270.
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Harparkash Kaur, Ingrid Fagerheim, Martin Grootveld, Alain Puppo & Barry Halliwell. (1988) Aromatic hydroxylation of phenylalanine as an assay for hydroxyl radicals: Application to activated human neutrophils and to the heme protein leghemoglobin. Analytical Biochemistry 172:2, pages 360-367.
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Barry Halliwell, Martin Grootveld & John M. C. Gutteridge. 1988. Methods of Biochemical Analysis. Methods of Biochemical Analysis 59 90 .
Benon H. J. Bielski. 1988. Oxygen Radicals in Biology and Medicine. Oxygen Radicals in Biology and Medicine 123 130 .
Arthur L. SagoneJr.Jr.. 1988. The Respiratory Burst and Its Physiological Significance. The Respiratory Burst and Its Physiological Significance 245 276 .
Okezie I. Aruoma, Martin Grootveld & Barry Halliwell. (1987) The role of iron in ascorbate-dependent deoxyribose degradation. Evidence consistent with a site-specific hydroxyl radical generation caused by iron ions bound to the deoxyribose molecule. Journal of Inorganic Biochemistry 29:4, pages 289-299.
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P.Christopher Moorhouse, Martin Grootveld, Barry Halliwell, J.Gregory Quinlan & John M.C. Gutteridge. (1987) Allopurinol and oxypurinol are hydroxyl radical scavengers. FEBS Letters 213:1, pages 23-28.
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Barry Halliwell, Mohammed Wasil & Martin Grootveld. (1987) Biologically significant scavenging of the myeloperoxidase-derived oxidant hypochlorous acid by ascorbic acid. FEBS Letters 213:1, pages 15-17.
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Barry Halliwell. (2007) Free radicals and metal ions in health and disease. Proceedings of the Nutrition Society 46:1, pages 13-26.
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Christine C. Winterbourn. (1987) The ability of scavengers to distinguish OH· production in the iron-catalyzed Haber-Weiss reaction: Comparison of four assays for OH·. Free Radical Biology and Medicine 3:1, pages 33-39.
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. (1997) Metal ions and oxygen radical reactions in human inflammatory joint disease. Philosophical Transactions of the Royal Society of London. B, Biological Sciences 311:1152, pages 659-671.
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