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Original Article

Iron Complexes and Their Reactivity in the Bleomycin Assay for Radical-Promoting Loosely-Bound Iron

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Pages 143-151 | Received 01 May 1986, Published online: 07 Jul 2009

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Hans Nohl, Katrin Staniek & Andrey V. Kozlov. (2005) The existence and significance of a mitochondrial nitrite reductase. Redox Report 10:6, pages 281-286.
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G. P. Biro, C. Ou, C. Ryan-MacFarlane & P. J. Anderson. (1995) Oxyradical Generation After Resuscitation of Hemorrhagic Shock with Blood or Stromafree Hemoglobin Solution. Artificial Cells, Blood Substitutes, and Biotechnology 23:6, pages 631-645.
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Howard M. Berger, Sharon Mumby & John M.C. Gutteridge. (1995) Ferrous Ions Detected in Iron-Overloaded Cord Blood Plasma From Preterm and Term Babies: Implications for Oxidative Stress. Free Radical Research 22:6, pages 555-559.
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John R. Pepper, Sharon Mumby & John M.C. Gutteridge. (1994) Transient Iron-Overload with Bleomycin-Detectable Iron Present During Cardiopulmonary Bypass Surgery. Free Radical Research 21:2, pages 53-58.
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John M C, Gutteridge Wu Cao & Mordechai Chevion. (1991) Bleomycin-Detectable Iron in Brain Tissue. Free Radical Research Communications 11:6, pages 317-320.
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Sandie Gerby, Mathias Simplicien, Pascale Duchez, Jean Chevaleyre, Zoran Ivanovic & Marija Vlaski-Lafarge. (2019) Hypoxia/hypercapnia prevents iron-dependent cold injuries in cord blood stem and progenitor cells. Cytotherapy 21:4, pages 460-467.
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John M.C. Gutteridge & Barry Halliwell. (2018) Mini-Review: Oxidative stress, redox stress or redox success?. Biochemical and Biophysical Research Communications 502:2, pages 183-186.
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Serdar Sivgin, Suleyman Baldane, Kemal Deniz, Gokmen Zararsiz, Leylagul Kaynar, Mustafa Cetin, Ali Unal & Bulent Eser. (2016) Increased Hepatic Iron Content Predicts Poor Survival in Patients With Iron Overload Who Underwent Allogeneic Hematopoietic Stem Cell Transplantation. Clinical Lymphoma Myeloma and Leukemia 16, pages S10-S18.
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Frieder Kröner & Jürgen Hubbuch. (2013) Systematic generation of buffer systems for pH gradient ion exchange chromatography and their application. Journal of Chromatography A 1285, pages 78-87.
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S. Mumby, K.F. Chung, J.E. McCreanor, E.D. Moloney, M.J.D. Griffiths & G.J. Quinlan. (2011) Pro-oxidant iron in exhaled breath condensate: A potential excretory mechanism. Respiratory Medicine 105:9, pages 1290-1295.
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Michael A.J. Zieger & Mahesh P. Gupta. (2009) Hypothermic preconditioning of endothelial cells attenuates cold-induced injury by a ferritin-dependent process. Free Radical Biology and Medicine 46:5, pages 680-691.
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Michael A. J. Zieger & Mahesh P. Gupta. (2017) Endothelial Cell Preservation at 10°C Minimizes Catalytic Iron, Oxidative Stress, and Cold-Induced Injury. Cell Transplantation 15:6, pages 499-510.
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J. Egberts, M.R. Hardeman & L.M. Luykx. (2004) Decreased deformability of donor red blood cells after intrauterine transfusion in the human fetus: possible reason for their reduced life span?. Transfusion 44:8, pages 1231-1237.
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Sharon Mumby, Rebecca L. Upton, Yan Chen, Salome J. Stanford, Gregory J. Quinlan, Andrew G. Nicholson, John M. C. Gutteridge, Nicholas J. Lamb & Timothy W. Evans. (2004) Lung heme oxygenase-1 is elevated in acute respiratory distress syndrome. Critical Care Medicine 32:5, pages 1130-1135.
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L.M. Luykx, H.M. Berger, J. Geerdink, H.H.H. Kanhai & J. Egberts. (2004) Non-protein-bound iron and free radical damage in fetuses with rhesus haemolytic disease: influence of intrauterine transfusions. BJOG: An International Journal of Obstetrics and Gynaecology 111:4, pages 303-310.
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Anjo M DraaismaJacek S Molicki, Nicole Verbeet, Rendel Munneke, Hans A Huysmans, Howard M Berger & Mark G Hazekamp. (2016) Increasing the antioxidative capacity of neonatal cardiopulmonary bypass prime solution: anin vitro study. Perfusion 18:6, pages 357-362.
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Hong Huang & Abdulla K. Salahudeen. (2002) Cold Induces Catalytic Iron Release of Cytochrome P-450 Origin: A Critical Step in Cold Storage-Induced Renal Injury. American Journal of Transplantation 2:7, pages 631-639.
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John M. C. Gutteridge & Barry Halliwell. 2002. Reactive Oxygen Species in Biological Systems. Reactive Oxygen Species in Biological Systems 189 218 .
Ameen A. Salahudeen, John K. Jenkins, Hong Huang, Kenneth Ndebele & Abdulla K. Salahudeen. (2001) OVEREXPRESSION OF HEME OXYGENASE PROTECTS RENAL TUBULAR CELLS AGAINST COLD STORAGE INJURY. Transplantation 72:9, pages 1498-1504.
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Sharon Mumby, Tat W Koh, John R Pepper & John M.C Gutteridge. (2001) Risk of iron overload is decreased in beating heart coronary artery surgery compared to conventional bypass. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1537:3, pages 204-210.
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S. S. Marwah, D. Wheelwright, A. D. Blann, C. Rea, R. Beresford, J. D. Phillips, J. Wright & D. Bareford. (2001) Vitamin E correlates inversely with non‐transferrin‐bound iron in sickle cell disease. British Journal of Haematology 114:4, pages 917-919.
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Maria Kapsokefalou & Dennis D Miller. (2007) Iron loading and large doses of intravenous ascorbic acid promote lipid peroxidation in whole serum in guinea pigs. British Journal of Nutrition 85:6, pages 681-687.
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K Hirano, T Morinobu, H Kim, M Hiroi, R Ban, S Ogawa, H Ogihara, H Tamai & T Ogihara. (2001) Blood transfusion increases radical promoting non-transferrin bound iron in preterm infants. Archives of Disease in Childhood - Fetal and Neonatal Edition 84:3, pages F188-F193.
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Sharon Mumby, Rajiv R. Chaturvedi, Joe Brierley, Christopher Lincoln, Andy Petros, Andrew N. Redington & John M.C. Gutteridge. (2000) Iron overload in paediatrics undergoing cardiopulmonary bypass. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1500:3, pages 342-348.
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Peter B. Anning, Yan Chen, Nicholas J. Lamb, Sharon Mumby, Gregory J. Quinlan, Timothy W. Evans & John M.C. Gutteridge. (1999) Iron overload upregulates haem oxygenase 1 in the lung more rapidly than in other tissues. FEBS Letters 447:1, pages 111-114.
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Steven M. LeVine, Michael J. Wulser & Sharon G. Lynch. (1998) Iron Quantification in Cerebrospinal Fluid. Analytical Biochemistry 265:1, pages 74-78.
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Sharon Mumby, Masahiko Koizumi, Naoyuki Taniguchi & John M.C Gutteridge. (1998) Reactive iron species in biological fluids activate the iron–sulphur cluster of aconitase. Biochimica et Biophysica Acta (BBA) - General Subjects 1380:1, pages 102-108.
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Diane C. LipscombLinda G. GormanRichard J. TraystmanPatricia D. Hurn. (1998) Low Molecular Weight Iron in Cerebral Ischemic Acidosis In Vivo. Stroke 29:2, pages 487-493.
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John M. C. Gutteridge. 1998. Free Radicals, Oxidative Stress, and Antioxidants. Free Radicals, Oxidative Stress, and Antioxidants 1 14 .
Mark Messent, David G. Sinclair, Gregory J. Quinlan, Sharon E. Mumby, John M. C. Gutteridge & Timothy W. Evans. (1997) Pulmonary vascular permeability after cardiopulmonary bypass and its relationship to oxidative stress. Critical Care Medicine 25:3, pages 425-429.
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Radhakrishna Baliga, Zhiwei Zhang & Sudhir V. Shah. (1996) Role of cytochrome P-450 in hydrogen peroxide-induced cytotoxicity to LLC-PK1 cells. Kidney International 50:4, pages 1118-1124.
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J. Pincemail, J. O. Defraigne & R. Limet. (1996) Oxidative stress in clinical situations - fact or fiction?. European Journal of Anaesthesiology 13:3, pages 219-234.
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John M.C. Gutteridge & Barry Halliwell. 1996. Neurodegeneration and Neuroprotection in Parkinson's Disease. Neurodegeneration and Neuroprotection in Parkinson's Disease 1 21 .
John M. C. Gutteridge & Gregory J. Quinlan. 1996. ARDS Acute Respiratory Distress in Adults. ARDS Acute Respiratory Distress in Adults 167 195 .
John R. Pepper, Sharon Mumby & John M.C. Gutteridge. (1995) Blood cardioplegia increases plasma iron overload and thiol levels during cardiopulmonary bypass. The Annals of Thoracic Surgery 60:6, pages 1735-1740.
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J. M. C. Gutteridge. 1995. Oxidative Stress and Aging. Oxidative Stress and Aging 287 302 .
JOHN M. C. GUTTERIDGE. (2006) Hydroxyl Radicals, Iron, Oxidative Stress, and Neurodegenerationa. Annals of the New York Academy of Sciences 738:1, pages 201-213.
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J M Gutteridge, G J Quinlan & T W Evans. (1994) Transient iron overload with bleomycin detectable iron in the plasma of patients with adult respiratory distress syndrome.. Thorax 49:7, pages 707-710.
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P Harrison, S S Marwah, R T Hughes & D Bareford. (1994) Non-transferrin bound iron and neutropenia after cytotoxic chemotherapy.. Journal of Clinical Pathology 47:4, pages 350-352.
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P.J. Evans & B. Halliwell. 1994. Oxygen Radicals in Biological Systems Part C. Oxygen Radicals in Biological Systems Part C 82 92 .
John M. C. Gutteridge. 1994. Metal Compounds in Cancer Therapy. Metal Compounds in Cancer Therapy 198 214 .
Moussa B. H. Youdim, Dorit Ben-Shachar & Peter Riederer. 1994. Etiopathogenesis. Etiopathogenesis 63 78 .
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Neil E. Moat, Timothy E. Evans, Gregory J. Quinlan & John M.C. Gutteridge. (1993) Chelatable iron and copper can be released from extracorporeally circulated blood during cardiopulmonary bypass. FEBS Letters 328:1-2, pages 103-106.
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JOHN M.C. GUTTERIDGE & BARRY HALLIWELL. 1993. Atmospheric Oxidation and Antioxidants. Atmospheric Oxidation and Antioxidants 71 99 .
R.J. Simpson, C.E. Cooper, K.B. Raja, B. Halliwell, P.J. Evans, O.I. Arouma, S. Singh & A.M. Konijn. (1992) Non-transferrin-bound iron species in the serum of hypotransferrinaemic mice. Biochimica et Biophysica Acta (BBA) - General Subjects 1156:1, pages 19-26.
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F. N. Al‐Refaie, D. G. Wickens, B. Wonke, G. J. Kontoghiorghes & A. V. Hoffbrand. (2008) Serum non‐transferrin‐bound iron in beta‐thalassaemia major patients treated with desferrioxamine and L1. British Journal of Haematology 82:2, pages 431-436.
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John M. C. Gutteridge. (1992) Iron and oxygen radicals in brain. Annals of Neurology 32:S1, pages S16-S21.
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D. J. Anderson, F. Van Lente, F. S. Apple, S. C. Kazmierczak, J. A. Lott, M. K. Gupta, N. McBride, W. E. Katzin, R. E. Scott & . et al.. (2002) Clinical chemistry. Analytical Chemistry 63:12, pages 165-270.
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Ewa Gajewski, Okezie I. Aruoma, Miral Dizdaroglu & Barry Halliwell. (2002) Bleomycin-dependent damage to the bases in DNA is a minor side reaction. Biochemistry 30:9, pages 2444-2448.
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John M C Gutteridge. 1991. Oxidative Damage & Repair. Oxidative Damage & Repair 355 363 .
Harold G. Parkes, Rosamund E. Allen, Alexandra Furst, David R. Blake & Martin C. Grootveld. (1991) Speciation of non-transferrin-bound iron ions in synovial fluid from patients with rheumatoid arthritis by proton nuclear magnetic resonance spectroscopy. Journal of Pharmaceutical and Biomedical Analysis 9:1, pages 29-32.
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Martin Grootveld, DavidR Blake & Peter Merry. (1990) Iron overload, free radical damage, and rhesus haemolytic disease. The Lancet 335:8704, pages 1530-1531.
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John M.C. Gutteridge & Barry Halliwell. (1989) 1 Iron toxicity and oxygen radicals. Baillière's Clinical Haematology 2:2, pages 195-256.
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M Grootveld, J D Bell, B Halliwell, O I Aruoma, A Bomford & P J Sadler. (1989) Non-transferrin-bound iron in plasma or serum from patients with idiopathic hemochromatosis. Journal of Biological Chemistry 264:8, pages 4417-4422.
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B. Halliwell, O.I. Aruoma, G. Mufti & A. Bomford. (1988) Bleomycin-detectable iron in serum from leukaemic patients before and after chemotherapy Therapeutic implications for treatment with oxidant-generating drugs. FEBS Letters 241:1-2, pages 202-204.
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