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Free Radical Research Communications Volume 6, 1989 - Issue 1
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Original Article

Antioxidant Activity of 5-Hydroxytryptophan, 5-Hydroxyindole, and Dopa Against Microsomal Lipid Peroxidation and Its Dependence on Vitamin E

Enrique Cadenas Department of Pathology II, University of Linköping, S-581 85, Linköping, Sweden
,
Michael G. Simic Center for Radiation Research, National Bureau of Standards, Gaithersburg, MD, 20899, USA
&
Helmut Sies Institut für Physiologische Chemie I. Universität Düsseldorf, Moorenstrasse 5, D-4000, Düsseldorf I, FRG
Pages 11-17 | Received 30 Aug 1988, Published online: 07 Jul 2009

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Enrique Cadenas & Helmut Sies. (1998) The Lag Phase. Free Radical Research 28:6, pages 601-609.
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E. A. Lissi, M. Faure, N. Montoya & L. A. Videla. (1991) Reactivity of Indole Derivatives Towards Oxygenated Radicals. Free Radical Research Communications 15:4, pages 211-222.
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Yildirim Kayacan, Hayrullah Yazar, Günay Cerit & Babak Elmi Ghojebeigloo. (2019) A new oxidative stress indicator: Effect of 5-hydroxytryptophan on thiol-disulfide homeostasis in exercise. Nutrition 63-64, pages 114-119.
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Basel A. Abdel-Wahab & Ragaa H. Salama. (2011) Venlafaxine protects against stress-induced oxidative DNA damage in hippocampus during antidepressant testing in mice. Pharmacology Biochemistry and Behavior 100:1, pages 59-65.
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King-Thom Chung & Gopi S. Gadupudi. (2011) Possible roles of excess tryptophan metabolites in cancer. Environmental and Molecular Mutagenesis 52:2, pages 81-104.
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Sergio Millán-Plano, Eduardo Piedrafita, Francisco J. Miana-Mena, Lorena Fuentes-Broto, Enrique Martínez-Ballarín, Laura López-Pingarrón, María A. Sáenz & Joaquín J. García. (2010) Melatonin and Structurally-Related Compounds Protect Synaptosomal Membranes from Free Radical Damage. International Journal of Molecular Sciences 11:1, pages 312-328.
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Sung Jin Bae, Jun Sik Lee, Eun Kyeong Lee, Ji Min Kim, Jehun Choi, Hyoung-Sam Heo, Byung Pal Yu & Hae Young Chung. (2010) The Anti-apoptotic Action of 5-Hydroxyindole: Protection of Mitochondrial Integrity. Biological and Pharmaceutical Bulletin 33:4, pages 550-555.
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M. C. Reyes-Gonzales, L. Fuentes-Broto, E. Martínez-Ballarín, F. J. Miana-Mena, C. Berzosa, F. A. García-Gil, M. Aranda & J. J. García. (2009) Effects of Tryptophan and 5-Hydroxytryptophan on the Hepatic Cell Membrane Rigidity Due to Oxidative Stress. Journal of Membrane Biology 231:2-3, pages 93-99.
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Luciane Rosa Feksa, Alexandra Latini, Virgínia Cielo Rech, Patrícia Bartels Feksa, Gustavo Duarte Waltereith Koch, Maria Fernanda Arevalo Amaral, Guilhian Leipnitz, Carlos Severo Dutra-Filho, Moacir Wajner & Clóvis Milton Duval Wannmacher. (2008) Tryptophan administration induces oxidative stress in brain cortex of rats. Metabolic Brain Disease 23:2, pages 221-233.
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Vesna Petrović, Biljana Buzadžić, Aleksandra Korać, Ana Vasilijević, Aleksandra Janković, Ksenija Mićunović & Bato Korać. (2008) Antioxidative defence alterations in skeletal muscle during prolonged acclimation to cold: role of l -arginine/NO-producing pathway . Journal of Experimental Biology 211:1, pages 114-120.
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Rafal A. Derlacz, Malgorzata Sliwinska, Anna Piekutowska, Katarzyna Winiarska, Jakub Drozak & Jadwiga Bryla. (2007) Melatonin is more effective than taurine and 5-hydroxytryptophan against hyperglycemia-induced kidney-cortex tubules injury. Journal of Pineal Research 42:2, pages 203-209.
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Antoaneta Zheleva, Anna Tolekova, Momchil Zhelev, Veselina Uzunova, Magdalena Platikanova & Vesselina Gadzheva. (2007) Free radical reactions might contribute to severe alpha amanitin hepatotoxicity – A hypothesis. Medical Hypotheses 69:2, pages 361-367.
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Luciane Rosa Feksa, Alexandra Latini, Virgínia Cielo Rech, Moacir Wajner, Carlos Severo Dutra-Filho, Angela Terezinha de Souza Wyse & Clovis Milton Duval Wannmacher. (2006) Promotion of oxidative stress by l-tryptophan in cerebral cortex of rats. Neurochemistry International 49:1, pages 87-93.
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Christian Keithahn & Alexander Lerchl. (2005) 5-Hydroxytryptophan is a more potent in vitro hydroxyl radical scavenger than melatonin or vitamin C. Journal of Pineal Research 38:1, pages 62-66.
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Antonio Rescigno & Enrico Sanjust. 2002. Bioactive Natural Products. Bioactive Natural Products 965 1028 .
Herschel Sidransky. 2001. Tryptophan. Tryptophan 189 207 .
Peter M. Abuja, Riccardo Albertini & Hermann Esterbauer. (1997) Simulation of the Induction of Oxidation of Low-Density Lipoprotein by High Copper Concentrations:  Evidence for a Nonconstant Rate of Initiation. Chemical Research in Toxicology 10:6, pages 644-651.
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L. H. Jones, D. S. P. Abdalla & J. C. Freitas. (1995) Effects of indole-3-acetic acid on croton oil- and arachidonic acid-induced mouse ear edema. Inflammation Research 44:9, pages 372-375.
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Misato Iwatsuki, Erika Komuro & Etsuo Niki. (1995) Antioxidant Activities of Aminophenols against Oxidation of Methyl Linoleate in Solution. Bulletin of the Chemical Society of Japan 68:2, pages 620-624.
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Richard A. Larson. 1995. Oxidative Stress and Antioxidant Defenses in Biology. Oxidative Stress and Antioxidant Defenses in Biology 210 237 .
Arthur I. Cederbaum, Ewa K Ukielka & Hernan Speiskyf. (1992) Inhibition of rat liver microsomal lipid peroxidation by boldine. Biochemical Pharmacology 44:9, pages 1765-1772.
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Milan Stefek, Maria Masarykova & Ludek Benes. (2009) Inhibition of Cumene Hydroperoxide‐Induced Lipid Peroxidation by a Novel Pyridoindole Antioxidant in Rat Liver Microsomes. Pharmacology & Toxicology 70:6, pages 407-411.
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Lubica Horakova, Karlis Briviba & Helmut Sies. (1992) Antioxidant activity of the pyridoindole stobadine in liposomal and microsomal lipid peroxidation. Chemico-Biological Interactions 83:1, pages 85-93.
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Vasanthy Narayanaswami & Helmut Sies. (1990) Oxidative damage to mitochondria and protection by ebselen and other antioxidants. Biochemical Pharmacology 40:7, pages 1623-1629.
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Heiner Scholich, Michael E. Murphy & Helmut Sies. (1989) Antioxidant activity of dihydrolipoate against microsomal lipid peroxidation and its dependence on α-tocopherol. Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism 1001:3, pages 256-261.
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H. Sies. 1989. Selenium in Biology and Medicine. Selenium in Biology and Medicine 153 162 .

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