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Original Article

Electrochemical Characteristics of Nitro-Heterocyclic Compounds of Biological Interest IV. Lifetime of the Metronidazole Radical Anion

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Pages 39-45 | Received 05 Oct 1988, Published online: 07 Jul 2009

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M. Rybczynska, C. Feo, M. Marden & C. Poyart. (1993) Abnormal rheological response of erythrocytes caused by nitroimidazoles and hyperthermia. International Journal of Hyperthermia 9:2, pages 313-323.
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Tanya Symons, Joanne H. Tocher, Derek A. Tocher & David I. Edwards. (1991) Electrochemical Studies of Nitroheterocyclic Compounds of Biological Interest. VII. Effect of Electrode Material. Free Radical Research Communications 14:1, pages 33-40.
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Joanne H. Tocher & David I. Edwards. (1990) Electrochemical Characteristics of Nitroheterocyclic Compounds of Biological Interest VI. The Misonidazole Radical Anion. Free Radical Research Communications 9:1, pages 49-54.
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M. Rybczynska. (1990) The Evaluation of Erythrocyte Membrane Response to Combined Treatment of Radiation and Nitroimidazoles. International Journal of Radiation Biology 58:2, pages 313-323.
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P.C Mandal. (2004) Reactions of the nitro radical anion of metronidazole in aqueous and mixed solvent: a cyclic voltammetric study. Journal of Electroanalytical Chemistry 570:1, pages 55-61.
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M. Castelli, M. Malagoli, L. Lupo, S. Roffia, F. Paolucci, C. Cermelli, A. Zanca & G. Baggio. (2000) Cytotoxicity and probable mechanism of action of sulphimidazole. Journal of Antimicrobial Chemotherapy 46:4, pages 541-550.
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Luis J. Núñez-Vergara, J. Aldunate, M.E. Letelier, S. Bollo, Y. Repetto, A. Morello, P.L. Spencer & J.A. Squella. (1995) Nitro radical anion formation from nifurtimox II: electrochemical evidence. Bioelectrochemistry and Bioenergetics 38:2, pages 355-358.
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P. Zuman & E. Rupp. (2005) Polarographic and electrochemical studies of some aromatic nitro compounds: Part VIII. Effects of solvents and surfactants on current–voltage curves obtained with DC and differential pulse polarography. Electroanalysis 7:2, pages 132-137.
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Luis J. Núñez-Vergara, F. García, M.M. Domínguez, J. de la Fuente & J.A. Squella. (1995) In situ reactivity of the electrochemically generated nitro radical anion from nitrendipine with glutathione, adenine and uracil. Journal of Electroanalytical Chemistry 381:1-2, pages 215-219.
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Joanne H. Tocher & David I. Edwards. (1994) Evidence for the direct interaction of reduced metronidazole derivatives with DNA bases. Biochemical Pharmacology 48:6, pages 1089-1094.
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J.A. Squella, C. Solabarrieta & L.J. Nuñez-Vergara. (1993) A nitro radical anion formation from nifedipine: an electrochemical approach. Chemico-Biological Interactions 89:2-3, pages 197-205.
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Agnieszka Kalandyk & Jadwiga Stroka. (1993) Electroreduction of nitrobenzene on the mercury electrode in water + HMPA solutions. Journal of Electroanalytical Chemistry 346:1-2, pages 323-338.
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Luis J. Nuñez-Vergara, S. Bollo, A.F. Alvarez, J.A. Squella & M. Blazquez. (1993) Nitro radical anion formation from nimodipine. Journal of Electroanalytical Chemistry 345:1-2, pages 121-133.
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D. Dumanović, J. Jovanović, D. Sužnjević, M. Erceg & P. Zuman. (2005) Polarographic and electrochemical studies of some aromatic and heterocyclic nitro compounds, part III: Electroreduction of mono‐ and dinitropyrazoles and ‐imidazoles. Electroanalysis 4:9, pages 871-887.
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Petr Zuman, Zbigniew Fijalek, Dragica Dumanovic & Desanka Sužnjević. (2005) Polarographic and electrochemical studies of some aromatic and heterocyclic nitro compounds, part I: General mechanistic aspects. Electroanalysis 4:8, pages 783-794.
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Joanne H Tocher & David I Edwards. (1992) The interaction of reduced metronidazole with DNA bases and nucleosides. International Journal of Radiation Oncology*Biology*Physics 22:4, pages 661-663.
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J.A. Squella, J. Mosre, M. Blázquez & Luis J. Nú≈nez-Vergara. (1991) Cyclic voltammetric study of the nitro radical anion from nitrendipine generated electrochemically. Journal of Electroanalytical Chemistry and Interfacial Electrochemistry 319:1-2, pages 177-184.
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Petr Zuman & Zbigniew Fijalek. (1990) Contribution to the understanding of the reduction mechanism of nitrobenzene. Journal of Electroanalytical Chemistry and Interfacial Electrochemistry 296:2, pages 583-588.
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