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Original Article

Antioxidant Activity of Ebselen and Related Selenoorganic Compounds in Microsomal Lipid Peroxidation

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Pages 237-244 | Received 12 Mar 1990, Published online: 07 Jul 2009

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Michael Parnham & Helmut Sies. (2000) Ebselen: prospective therapy for cerebral ischaemia. Expert Opinion on Investigational Drugs 9:3, pages 607-619.
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S. X. Liu, Y. Chen, M. Zhou, W. Y. Wen & M. J. Sun. (1995) Inhibitory effect of ebselen on the oxidation of low density lipoprotein. Redox Report 1:5, pages 357-360.
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Yu Ri Kim, Nam Jin Lee, Jung Ok Ban, Hwan Soo Yoo, Yong Moon Lee, Yeo Pyo Yoon, So Young Eum, Heon Sang Jeong, Do-young Yoon, Sang Bae Han & Jin Tae Hong. (2013) Curative Effects of Thiacremonone against Acetaminophen-Induced Acute Hepatic Failure via Inhibition of Proinflammatory Cytokines Production and Infiltration of Cytotoxic Immune Cells and Kupffer Cells. Evidence-Based Complementary and Alternative Medicine 2013, pages 1-13.
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Mouslim Messali, Mostafa Abboudi, Mohamed R. Aouad, Nadjet Rezki & Léon E. Christiaens. (2011) Synthesis and Characterization of a New Five and Six Membered Selenoheterocyclic Compounds Homologues of Ebselen. Organic Chemistry International 2011, pages 1-7.
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R.F. Burk & K.E. Hill. 2010. Comprehensive Toxicology. Comprehensive Toxicology 229 242 .
Jung Ok Ban, Hee Soon Lee, Heon-Sang Jeong, Sugkil Song, Bang Yeon Hwang, Dong Cheul Moon, Do Young Yoon, Sang Bae Han & Jin Tae Hong. (2009) Thiacremonone Augments Chemotherapeutic Agent–Induced Growth Inhibition in Human Colon Cancer Cells through Inactivation of Nuclear Factor-κB. Molecular Cancer Research 7:6, pages 870-879.
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Mouslim Messali, Léon E. Christiaens, Solhe F. Alshahateet & Fethi Kooli. (2007) Synthesis of 4H-benzo[e]-1,2-selanazin-4-one derivatives: a new heterocyclic ring system. Tetrahedron Letters 48:42, pages 7448-7451.
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Jung Ok Ban, Dong Yeon Yuk, Koan Sik Woo, Tae Myoung Kim, Ung Soo Lee, Heon-Sang Jeong, Dae Joong Kim, Yeun Bok Chung, Bang Yeon Hwang, Ki Wan Oh & Jin Tae Hong. (2007) Inhibition of Cell Growth and Induction of Apoptosis via Inactivation of NF-κB by a Sulfurcompound Isolated From Garlic in Human Colon Cancer Cells. Journal of Pharmacological Sciences 104:4, pages 374-383.
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Masami Tanaka, Nahomi Takezawa, Toshio Kumai, Minoru Watanabe, Naoki Matsumoto, Sachiko Nakaya & Shinichi Kobayashi. (2002) Ebselen Protects against the Reduction in Levels of Drug-Metabolizing Enzymes in Livers of Rats with Deoxycholic Acid-Induced Liver Injury. Pharmacology & Toxicology 91:2, pages 64-70.
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Govindasamy Mugesh, Wolf-Walther du Mont & Helmut Sies. (2001) Chemistry of Biologically Important Synthetic Organoselenium Compounds. Chemical Reviews 101:7, pages 2125-2180.
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Karam El-Bayoumy. (2001) The protective role of selenium on genetic damage and on cancer. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 475:1-2, pages 123-139.
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Cheng-Feng Yang, Han-Ming Shen & Choon-Nam Ong. (2000) Ebselen Induces Apoptosis in HepG2 Cells through Rapid Depletion of Intracellular Thiols. Archives of Biochemistry and Biophysics 374:2, pages 142-152.
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Francisco Bosch-Morell, Joaquı́n Romá, Francisco J Puertas, Nuria Marı́n, Manuel Dı́az-Llopis & Francisco J Romero. (1999) Efficacy of the antioxidant ebselen in experimental uveitis. Free Radical Biology and Medicine 27:3-4, pages 388-391.
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Cheng-Feng Yang, Han-Ming Shen & Choon-Nam Ong. (1999) Protective effect of ebselen against hydrogen peroxide-induced cytotoxicity and DNA damage in HepG2 cells. Biochemical Pharmacology 57:3, pages 273-279.
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Seiichi Matsugo, Liang-Jun Yan, Tetsuya Konishi, Hong-Duk Youn, John K. Lodge, Heinz Ulrich & Lester Packer. (1997) The Lipoic Acid Analogue 1,2-Diselenolane-3-pentanoic Acid Protects Human Low Density Lipoprotein against Oxidative Modification Mediated by Copper Ion. Biochemical and Biophysical Research Communications 240:3, pages 819-824.
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Michitaka Ozaki, Michio Nakamura, Satoshi Teraoka & Kazuo Ota. (1997) Ebselen, a novel anti-oxidant compound, protects the rat liver from ischemia-reperfusion injury. Transplant International 10:2, pages 96-102.
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Helmut Sies & Hiroshi Masumoto. 1996. 229 246 .
Shahab Uddin & Sarfraz Ahmad. (1995) Dietary antioxidants protection against oxidative stress. Biochemical Education 23:1, pages 2-7.
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Enrique Cadenas, Cecilia Giulivi, Fulvio Ursini & Alberto Boveris. 1994. In Vitro Toxicity Indicators. In Vitro Toxicity Indicators 384 399 .
Helmut Sies. 1994. Oxygen Radicals in Biological Systems Part D. Oxygen Radicals in Biological Systems Part D 476 482 .
Helmut Sies. (1993) Ebselen, a selenoorganic compound as glutathione peroxidase mimic. Free Radical Biology and Medicine 14:3, pages 313-323.
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Noriko Noguchi, Yasukazu Yoshida, Hajime Kaneda, Yorihiro Yamamoto & Etsuo Niki. (1992) Action of ebselen as an antioxidant against lipid peroxidation. Biochemical Pharmacology 44:1, pages 39-44.
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Pierre V. Jacquemin, Léon E. Christiaens, Marcel J. Renson, Michel J. Evers & Norbert Dereu. (1992) Synthesis of 2H,3-4-Dihydro-1,2-benzoselenazin-3-one and derivatives : A new heterocyclic ring system.. Tetrahedron Letters 33:27, pages 3863-3866.
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Lubica Horakova, Karlis Briviba & Helmut Sies. (1992) Antioxidant activity of the pyridoindole stobadine in liposomal and microsomal lipid peroxidation. Chemico-Biological Interactions 83:1, pages 85-93.
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Jon D. Gower, Nick J. Lane, J.Graham Goddard, Sanjev Manek, Ian J. Ambrose & Colin J. Green. (1992) Ebselen. Biochemical Pharmacology 43:11, pages 2341-2348.
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Ji-Feng Wang, Pavel Komarov, Helmut Sies & Herbert de Groot. (1992) Inhibition of superoxide and nitric oxide release and protection from reoxygenation injury by ebselen in rat kupffer cells. Hepatology 15:6, pages 1112-1116.
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Carlos Pascual & Cheyla Romay. (2005) Effect of antioxidants on chemiluminescence produced by reactive oxygen species. Journal of Bioluminescence and Chemiluminescence 7:2, pages 123-132.
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Vasanthy Narayanaswami & Helmut Sies. (1990) Oxidative damage to mitochondria and protection by ebselen and other antioxidants. Biochemical Pharmacology 40:7, pages 1623-1629.
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