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Free Radical Research Communications Volume 10, 1990 - Issue 6
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Original Article

Generation of Radical Anions of Nifurtimox and Related Nitrofuran Compounds By Ascorbate

S. H. Fernandez Villamil Bioenergetics Research Centre, School of Medicine, University of Buenos Aires, Paraguay 2155, 1121, Buenos Aires, Argentina
,
M. Dubin Bioenergetics Research Centre, School of Medicine, University of Buenos Aires, Paraguay 2155, 1121, Buenos Aires, Argentina
,
M. A. Brusa Department of Chemistry, University of Mar del Plata, 7600, Mar del Plata, Argentina
,
R. P. Duran Department of Chemistry, University of Mar del Plata, 7600, Mar del Plata, Argentina
,
L. J. Perissinotti Department of Chemistry, University of Mar del Plata, 7600, Mar del Plata, Argentina
&
A. O. M. Stoppani Bioenergetics Research Centre, School of Medicine, University of Buenos Aires, Paraguay 2155, 1121, Buenos Aires, Argentina
Pages 351-360 | Received 09 Feb 1990, Accepted 20 Apr 1990, Published online: 07 Jul 2009

Citations (9)

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P. Aracena, C. Lazo-Hernández, A. Molina-Berríos, D. R. Sepúlveda, C. Reinoso, J. I. Larraín, J. Navarro & M. E. Letelier. (2014) Microsomal oxidative stress induced by NADPH is inhibited by nitrofurantoin redox biotranformation. Free Radical Research 48:2, pages 129-136.
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S. H. Fernández Villamil, M. Dubin, M. P. Molina Portela, L. J. Perissinotti, M. A. Brusa & A. O. M. Stoppani. (1997) Semiquinone production by lipophilic o-naphthoquinones. Redox Report 3:4, pages 245-252.
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M. Paulino-blumenfeld, M. Hansz, N. Hikichi & A. O. M. Stoppani. (1992) Electronic Properties and Free Radical Production by Nitrofuran Compounds. Free Radical Research Communications 16:4, pages 207-215.
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M. Dubin, S. H. Fernandez Villamil, M. Paulino De Blumenfeld & A. O. M. Stoppani. (1991) Inhibition of Microsomal Lipid Peroxidation and Cytochrome P-450-Catalyzed Reactions by Nitrofuran Compounds. Free Radical Research Communications 14:5-6, pages 419-431.
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Articles from other publishers (5)

Aldana B. Moroni, Natalia L. Calvo & Teodoro S. Kaufman. (2023) Selected Aspects of the Analytical and Pharmaceutical Profiles of Nifurtimox. Journal of Pharmaceutical Sciences.
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M.E. Letelier, F. Hidalgo-Castro, M. López-Valladares, N. Ibacache, C. Pérez, J. Brunner, J. González, R. Gutmann, C. Lazo-Henríquez, C. Gallardo-Garrido, A. Molina-Berríos & E. Ossandón. (2017) BG126 ® phytodrug improves urinary tract infection treatment with nitrofurantoin in adult women in a double-blind randomized clinical trial. Journal of Herbal Medicine 9, pages 60-67.
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M. Faúndez, M. Rojas, P. Bohle, C. Reyes, M.E. Letelier, M.E. Aliaga, H. Speisky, E. Lissi & C. López-Alarcón. (2011) Pyrogallol red oxidation induced by superoxide radicals: Application to evaluate redox cycling of nitro compounds. Analytical Biochemistry 419:2, pages 284-291.
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Igal Elingold, Melisa I. Taboas, Marta B. Casanova, Mónica Galleano, Raphael S.F. Silva, Rubem F.S. Menna-Barreto, Antonio Ventura Pinto, Solange L. de Castro, Lidia E. Costa & Marta Dubin. (2009) Mechanism of action of novel naphthofuranquinones on rat liver microsomal peroxidation. Chemico-Biological Interactions 182:2-3, pages 213-219.
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Marta Dubin, Patricia H. Carrizo, Ana M. Biscardi, Silvia H. Fernandez Villamil & Andrés O.M. Stoppani. (1994) Effect of 5-nitroindole on adenylate energy charge, oxidative phosphorylation, and lipid peroxidation in rat hepatocytes. Biochemical Pharmacology 48:7, pages 1483-1492.
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