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Original Article

Esr Spin Trapping Studies Into of Nature of the Oxidizing Species Formed in the Fenton Reaction: Pitfalls Associated With of Use Of 5,5-Dimethyl-1-Pyrroline-n-Oxide in the Detection of the Hydroxyl Radical

Pages 43-57 | Received 15 Oct 1992, Published online: 07 Jul 2009

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Yasumasa Okazaki, Nanami Ito, Hiromasa Tanaka, Masaru Hori & Shinya Toyokuni. (2022) Non-thermal plasma elicits ferrous chloride-catalyzed DMPO-OH. Free Radical Research 56:9-10, pages 595-606.
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Jan Pláteník, Pavel Stopka, Martin Vejražka & Stanislav Štípek. (2001) Quinolinic acid — Iron(II) complexes: Slow autoxidation, but enhanced hydroxyl radical production in the Fenton reaction. Free Radical Research 34:5, pages 445-459.
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Angele Viola, Andre Jeunet, Richard Decreau, Michel Chanon & Michel Julliard. (1998) ESR Studies of a Series of Phthalocyanines. Mechanism of Phototoxicity. Comparative Quantitation of O2-using ESR Spin-Trapping and Cytochrome c Reduction Techniques. Free Radical Research 28:5, pages 517-532.
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G. D. Castro, A. M. A. Delgado de Layño & J. A. Castro. (1997) Hydroxyl and 1-hydroxyethyl free radical detection using spin traps followed by derivatization and gas chromatography—mass spectrometry. Redox Report 3:5-6, pages 343-347.
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Alexander V. Kachur, Yefim Manevich & John E. Biaglow. (1997) Effect of Purine Nucleoside Phosphates on OH-Radical Generation by Reaction of Fe2+ With Oxygen. Free Radical Research 26:5, pages 399-408.
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J. Gutierrez Correa & A. O. M. Stoppani. (1993) Inactivation of Lipoamide Dehydrogenase by Cobalt(II) and Iron(II) Fenton Systems: Effect of Metal Chelators, Thiol Compounds and Adenine Nucleotides. Free Radical Research Communications 19:5, pages 303-314.
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Shuzhao Pei, Shijie You, Jun Ma, Xiaodong Chen & Nanqi Ren. (2020) Electron Spin Resonance Evidence for Electro-generated Hydroxyl Radicals. Environmental Science & Technology 54:20, pages 13333-13343.
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Xingxing Zheng, Yanmei Chen, Jingwen Ran & Li Li. (2020) Synthesis, crystal structure, photoluminescence and catalytic properties of a novel cuprous complex with 2,3-pyrazinedicarboxylic acid ligands. Scientific Reports 10:1.
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Alexander V. Vorontsov. (2019) Advancing Fenton and photo-Fenton water treatment through the catalyst design. Journal of Hazardous Materials 372, pages 103-112.
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Juan Manuel Lázaro-Martínez, Lucía Victoria Lombardo Lupano, Lidia Leonor Piehl, Enrique Rodríguez-Castellón & Viviana Campo Dall’ Orto. (2016) New Insights about the Selectivity in the Activation of Hydrogen Peroxide by Cobalt or Copper Hydrogel Heterogeneous Catalysts in the Generation of Reactive Oxygen Species. The Journal of Physical Chemistry C 120:51, pages 29332-29347.
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Larissa C. Carvalho do Lago, Andreza C. Matias, Cassiana S. Nomura & Giselle Cerchiaro. (2011) Radical production by hydrogen peroxide/bicarbonate and copper uptake in mammalian cells: Modulation by Cu(II) complexes. Journal of Inorganic Biochemistry 105:2, pages 189-194.
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Jessica I. Nieto-JuarezKatarzyna PierzchłaAndrzej SienkiewiczTamar Kohn. (2010) Inactivation of MS2 coliphage in Fenton and Fenton-like systems: role of transition metals, hydrogen peroxide and sunlight. Environmental Science & Technology 44:9, pages 3351-3356.
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Derek F. Laine, Alexander Blumenfeld & I. Francis Cheng. (2008) Mechanistic Study of the ZEA Organic Pollutant Degradation System: Evidence for H 2 O 2 , HO•, and the Homogeneous Activation of O 2 by Fe II EDTA . Industrial & Engineering Chemistry Research 47:17, pages 6502-6508.
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Lisa K. Folkes, Martin Christlieb, Edyta Madej, Michael R. L. Stratford & Peter Wardman. (2007) Oxidative Metabolism of Combretastatin A-1 Produces Quinone Intermediates with the Potential To Bind to Nucleophiles and To Enhance Oxidative Stress via Free Radicals. Chemical Research in Toxicology 20:12, pages 1885-1894.
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Zhiyong Cheng & Yuanzong Li. (2007) What Is Responsible for the Initiating Chemistry of Iron-Mediated Lipid Peroxidation:  An Update. Chemical Reviews 107:3, pages 748-766.
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Vuk Maksimović, Miloš Mojović & Željko Vučinić. (2006) Monosaccharide–H2O2 reactions as a source of glycolate and their stimulation by hydroxyl radicals. Carbohydrate Research 341:14, pages 2360-2369.
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Sayuri Shirai, Masayuki Ominato, Takekazu Shimazu, Katuhide Toyama, Goichi Ogimoto, Tomoya Fujino, Takashi Yasuda, Takeo Sato, Teruhiko Maeba, Shigeru Owada & Kenjiro Kimura. (2005) Imbalance between production and scavenging of hydroxyl radicals in patients maintained on hemodialysis. Clinical and Experimental Nephrology 9:4, pages 310-314.
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Andrew Lawrence, Clare M. Jones, Peter Wardman & Mark J. Burkitt. (2003) Evidence for the Role of a Peroxidase Compound I-type Intermediate in the Oxidation of Glutathione, NADH, Ascorbate, and Dichlorofluorescin by Cytochrome c/H2O2. Journal of Biological Chemistry 278:32, pages 29410-29419.
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Mark J. Burkitt. (2019) Chemical, Biological and Medical Controversies Surrounding the Fenton Reaction. Progress in Reaction Kinetics and Mechanism 28:1, pages 75-104.
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Clare M. Jones, Andrew Lawrence, Peter Wardman & Mark J. Burkitt. (2002) Electron paramagnetic resonance spin trapping investigation into the kinetics of glutathione oxidation by the superoxide radical: re-evaluation of the rate constant. Free Radical Biology and Medicine 32:10, pages 982-990.
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Shiho Ohnishi, Mariko Murata & Shosuke Kawanishi. (2002) DNA damage induced by hypochlorite and hypobromite with reference to inflammation-associated carcinogenesis. Cancer Letters 178:1, pages 37-42.
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Kevin D. Welch, T.Zane Davis & Steven D. Aust. (2002) Iron Autoxidation and Free Radical Generation: Effects of Buffers, Ligands, and Chelators. Archives of Biochemistry and Biophysics 397:2, pages 360-369.
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Marc E. Van Eden & Steven D. Aust. (2001) The consequences of hydroxyl radical formation on the stoichiometry and kinetics of ferrous iron oxidation by human apoferritin. Free Radical Biology and Medicine 31:8, pages 1007-1017.
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Mariko MurataYuriko BanshoSumiko InoueKimiko ItoShiho OhnishiKaoru MidorikawaShosuke Kawanishi. (2001) Requirement of Glutathione and Cysteine in Guanine-Specific Oxidation of DNA by Carcinogenic Potassium Bromate. Chemical Research in Toxicology 14:6, pages 678-685.
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Mark J Burkitt & Peter Wardman. (2001) Cytochrome c Is a Potent Catalyst of Dichlorofluorescin Oxidation: Implications for the Role of Reactive Oxygen Species in Apoptosis. Biochemical and Biophysical Research Communications 282:1, pages 329-333.
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Bartolomé Quintero, José Jorge Morales, Miguel Quirós, Marı́a Isabel Martı́nez-Puentedura & Marı́a del Carmen Cabeza. (2000) Dediazoniation of p-hydroxybenzenediazonium ion in a neutral aqueous medium. Free Radical Biology and Medicine 29:5, pages 464-479.
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Noppawan Phumala, Tatsuo Ide & Hideo Utsumi. (1999) Noninvasive evaluation of in vivo free radical reactions catalyzed by iron using in vivo ESR spectroscopy. Free Radical Biology and Medicine 26:9-10, pages 1209-1217.
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RICHARD DECRÉAU, ANGÈLE VIOLA, MARIE JEANNE RICHARD, ANDRÉ JEUNETAN & MICHEL JULLIARD. (2012) Photodynamic Therapy: In Vitro Photosensitizing Efficacy of Bis(tri- n -hexylsiloxy)silicon Phthalocyanine against Achromic M6 Melanocytes. ESR Study of Active Oxygen Intermediates . Journal of Porphyrins and Phthalocyanines 02:05, pages 405-414.
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B. Halliwell. 1998. Oxidative Stress in Skeletal Muscle. Oxidative Stress in Skeletal Muscle 1 27 .
Claudio NapoliRoberto PaternòFrank M. FaraciHisao TaguchiAlfredo PostiglioneDonald D. Heistad. (1997) Mildly Oxidized Low-Density Lipoprotein Impairs Responses of Carotid but Not Basilar Artery in Rabbits. Stroke 28:11, pages 2266-2272.
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Roger V. Lloyd, Phillip M. Hanna & Ronald P. Mason. (1997) The Origin of the Hydroxyl Radical Oxygen in the Fenton Reaction. Free Radical Biology and Medicine 22:5, pages 885-888.
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D Ramakrishna Rao. (1996) Generation of reactive oxygen species by the redox cycling of nitroprusside. Biochimica et Biophysica Acta (BBA) - General Subjects 1289:2, pages 195-202.
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Jean-Baptiste Galey. 1996. 167 203 .
Christine C. Winterbourn. (1995) Toxicity of iron and hydrogen peroxide: the Fenton reaction. Toxicology Letters 82-83, pages 969-974.
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B.C. Gilbert. (1995) ESR studies of the generation and reactions of free radicals in chemical and biochemical systems. Radiation Physics and Chemistry 45:6, pages 889-890.
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Barry Halliwell. 1995. Active Oxygen in Biochemistry. Active Oxygen in Biochemistry 313 335 .
Barry Halliwell. (2009) Free Radicals and Antioxidants: A Personal View. Nutrition Reviews 52:8, pages 253-265.
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Masafumi Tomita, Toshiko Okuyama, Satoru Watanabe & Hiroko Watanabe. (1994) Quantitation of the hydroxyl radical adducts of salicylic acid by micellar electrokinetic capillary chromatography: oxidizing species formed by a Fenton reaction. Archives of Toxicology 68:7, pages 428-433.
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