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Original Article

A Hydrogen-Donating Monohydroxamate Scavenges Ferryl Myoglobin Radicals

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Pages 219-227 | Received 11 Aug 1993, Published online: 07 Jul 2009

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Maiken V. Kröger-Ohlsen, Mogens L. Andersen & Leif H. Skibsted. (2000) Reduction of ferrylmyoglobin by the spin trap N-tert-butyl-α-phenylnitrone (PBN) in aqueous solution and during freezing. Free Radical Research 32:4, pages 313-325.
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Maiken V. Kröger-Ohlsen, Mogens L. Andersen & Leif H. Skibsted. (1999) Acid-catalysed autoreduction of ferrylmyoglobin in aqueous solution studied by freeze quenching and ESR spectroscopy. Free Radical Research 30:4, pages 305-314.
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Lars Viborg Jórgensen, Henrik J. Andersen & Leif H. Skibsted. (1997) Kinetics of Reduction of Hypervalent Iron in Myoglobin by Crocin in Aqueous Solution. Free Radical Research 27:1, pages 73-87.
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Rakesh P. Patel, Dimitri A. Svistunenko, Victor M. Darley-usmar, Martyn C.R. Symons & Michael T. Wilson. (1996) Redox Cycling of Human Methaemoglobin by H2O2 Yields Persistent Ferryl Iron and Protein Based Radicals. Free Radical Research 25:2, pages 117-123.
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Dimitri A. Svistunenko, Rakesh P. Patel & Michael T. Wilson. (1996) An EPR Investigation of Human Methaemoglobin Oxidation by Hydrogen Peroxide: Methods to Quantify all Paramagnetic Species Observed in the Reaction. Free Radical Research 24:4, pages 269-280.
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Maria Lehene, Eva Fischer-Fodor, Florina Scurtu, Niculina D. Hădade, Emese Gal, Augustin C. Mot, Alina Matei & Radu Silaghi-Dumitrescu. (2020) Excess Ascorbate is a Chemical Stress Agent against Proteins and Cells. Pharmaceuticals 13:6, pages 107.
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Michelle Simons, Svetlana Gretton, Gary G.A. Silkstone, Badri S. Rajagopal, Victoria Allen-Baume, Natalie Syrett, Thoufieq Shaik, Nelida Leiva-Eriksson, Luca Ronda, Andrea Mozzarelli, Michael B. StraderAbdu I. AlayashBrandon J. Reeder & Chris E. Cooper. (2018) Comparison of the oxidative reactivity of recombinant fetal and adult human hemoglobin: implications for the design of hemoglobin-based oxygen carriers. Bioscience Reports 38:4.
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Brandon J. Reeder. (2017) Redox and Peroxidase Activities of the Hemoglobin Superfamily: Relevance to Health and Disease. Antioxidants & Redox Signaling 26:14, pages 763-776.
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Brandon J. Reeder. (2010) The Redox Activity of Hemoglobins: From Physiologic Functions to Pathologic Mechanisms. Antioxidants & Redox Signaling 13:7, pages 1087-1123.
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Paul W. BuehlerFelice D'Agnillo. (2010) Toxicological Consequences of Extracellular Hemoglobin: Biochemical and Physiological Perspectives. Antioxidants & Redox Signaling 12:2, pages 275-291.
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Egor Y. Plotnikov, Anastasia A. Chupyrkina, Irina B. Pevzner, Nickolaj K. Isaev & Dmitry B. Zorov. (2009) Myoglobin causes oxidative stress, increase of NO production and dysfunction of kidney's mitochondria. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1792:8, pages 796-803.
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Brandon J. Reeder, Marie Grey, Radu-Lucian Silaghi-Dumitrescu, Dimitri A. Svistunenko, Leif Bülow, Chris E. Cooper & Michael T. Wilson. (2008) Tyrosine Residues as Redox Cofactors in Human Hemoglobin. Journal of Biological Chemistry 283:45, pages 30780-30787.
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Michael T. Wilson & Brandon J. Reeder. (2008) Oxygen-binding haem proteins. Experimental Physiology 93:1, pages 128-132.
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Niels B.J. Vollaard, Brandon J. Reeder, Jerry P. Shearman, Patrick Menu, Michael T. Wilson & Chris E. Cooper. (2005) A new sensitive assay reveals that hemoglobin is oxidatively modified in vivo. Free Radical Biology and Medicine 39:9, pages 1216-1228.
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Dimitri A. Svistunenko. (2005) Reaction of haem containing proteins and enzymes with hydroperoxides: The radical view. Biochimica et Biophysica Acta (BBA) - Bioenergetics 1707:1, pages 127-155.
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Brandon J. ReederDimitri A. SvistunenkoChristopher E. CooperMichael T. Wilson. (2004) The Radical and Redox Chemistry of Myoglobin and Hemoglobin: From In Vitro Studies to Human Pathology. Antioxidants & Redox Signaling 6:6, pages 954-966.
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Darren J Malinoski, Matthew S Slater & Richard J Mullins. (2004) Crush injury and rhabdomyolysis. Critical Care Clinics 20:1, pages 171-192.
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Michael P. Murphy, Karim S. Echtay, Frances H. Blaikie, Jordi Asin-Cayuela, Helena M. Cochemé, Katherine Green, Julie A. Buckingham, Ellen R. Taylor, Fiona Hurrell, Gillian Hughes, Satomi Miwa, Christopher E. Cooper, Dimitri A. Svistunenko, Robin A.J. Smith & Martin D. Brand. (2003) Superoxide Activates Uncoupling Proteins by Generating Carbon-centered Radicals and Initiating Lipid Peroxidation. Journal of Biological Chemistry 278:49, pages 48534-48545.
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Dimitri A. Svistunenko, Brandon J. Reeder, Michael T. Wilson & Chris E. Cooper. (2019) Radical Formation and Migration in Myoglobins. Progress in Reaction Kinetics and Mechanism 28:1, pages 105-118.
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D. Garcı́a, R. Delgado, F.M. Ubeira & J. Leiro. (2002) Modulation of rat macrophage function by the Mangifera indica L. extracts Vimang and mangiferin. International Immunopharmacology 2:6, pages 797-806.
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M.C. Chang, Y.S. Ho, J.J. Lee, S.H. Kok, L.J. Hahn & J.H. Jeng. (2002) Prevention of the areca nut extract-induced unscheduled DNA synthesis of gingival keratinocytes by vitamin C and thiol compounds. Oral Oncology 38:3, pages 258-265.
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Barry Halliwell. 2001. Handbook of Antioxidants. Handbook of Antioxidants.
Valerian E. Kagan, Andrey V. Kozlov, Yulia Y. Tyurina, Anna A. Shvedova & Jack C. Yalowich. (2001) Antioxidant Mechanisms of Nitric Oxide Against Iron-Catalyzed Oxidative Stress in Cells. Antioxidants & Redox Signaling 3:2, pages 189-202.
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Dimitri A. Svistunenko. (2001) An EPR study of the peroxyl radicals induced by hydrogen peroxide in the haem proteins. Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology 1546:2, pages 365-378.
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Kevin P. Moore, Steve G. Holt, Rakesh P. Patel, Dimitri A. Svistunenko, William Zackert, David Goodier, Brandon. J. Reeder, Martine Clozel, Radhi Anand, Christopher E. Cooper, Jason D. Morrow, Michael T. Wilson, Victor Darley-Usmar & L. Jackson RobertsIIII. (1998) A Causative Role for Redox Cycling of Myoglobin and Its Inhibition by Alkalinization in the Pathogenesis and Treatment of Rhabdomyolysis-induced Renal Failure. Journal of Biological Chemistry 273:48, pages 31731-31737.
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Nikolai V. Gorbunov, Yulia Y. Tyurina, Guy Salama, Billy W. Day, H.Gregg Claycamp, Gregory Argyros, Nabil M. Elsayed & Valerian E. Kagan. (1998) Nitric Oxide Protects Cardiomyocytes againsttert-Butyl Hydroperoxide-Induced Formation of Alkoxyl and Peroxyl Radicals and Peroxidation of Phosphatidylserine. Biochemical and Biophysical Research Communications 244:3, pages 647-651.
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Ben-Zhan Zhu, Ronit Har-El, Nahum Kitrossky & Mordechai Chevion. (1998) New Modes of Action of Desferrioxamine. Free Radical Biology and Medicine 24:2, pages 360-369.
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Ben-Zhan Zhu, Ronit Har-El, Nahum Kitrossky & Mordechai Chevion. 1998. Free Radicals, Oxidative Stress, and Antioxidants. Free Radicals, Oxidative Stress, and Antioxidants 15 24 .
Dimitri A. Svistunenko, Rakesh P. Patel, Sergey V. Voloshchenko & Michael T. Wilson. (1997) The Globin-based Free Radical of Ferryl Hemoglobin Is Detected in Normal Human Blood. Journal of Biological Chemistry 272:11, pages 7114-7121.
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Maiken Kröger-Ohlsen & Leif H. Skibsted. (1997) Kinetics and Mechanism of Reduction of Ferrylmyoglobin by Ascorbate and d -Isoascorbate . Journal of Agricultural and Food Chemistry 45:3, pages 668-676.
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Dimitri A. Svistunenko, Nathan A. Davies, Michael T. Wilson, Ray P. Stidwill, Mervyn Singer & Chris E. Cooper. (1997) Free radical in blood: a measure of haemoglobin autoxidation in vivo? †. J. Chem. Soc., Perkin Trans. 2:12, pages 2539-2544.
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Vladimir B. Ritov, Sebastiano Banni, Jack C. Yalowich, Billy W. Day, H. Gregg Claycamp, Francesco P. Corongiu & Valerian E. Kagan. (1996) Non-random peroxidation of different classes of membrane phospholipids in live cells detected by metabolically integrated cis-parinaric acid. Biochimica et Biophysica Acta (BBA) - Biomembranes 1283:2, pages 127-140.
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