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Free Radical Research Volume 23, 1995 - Issue 6
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Original Article

Depletion of Alpha-Tocopherol in Human Atherosclerotic Lesions

K. L. H. Carpenter Division of Cellular Pathology, Department of Pathology, University of Cambridge, Cambridge, CB2 1QP, UK
,
K. H. Cheeseman Department of Biology and Biochemistry, Brunel University, Uxbridge, Middlesex, UB8 3PH, UK
,
C. Van Der Veen Division of Cellular Pathology, Department of Pathology, University of Cambridge, Cambridge, CB2 1QP, UK
,
S. E. Taylor Division of Cellular Pathology, Department of Pathology, University of Cambridge, Cambridge, CB2 1QP, UK
,
M. K. Walker Department of Biology and Biochemistry, Brunel University, Uxbridge, Middlesex, UB8 3PH, UK
&
M. J. Mitchinson Division of Cellular Pathology, Department of Pathology, University of Cambridge, Cambridge, CB2 1QP, UK
Pages 549-558 | Received 03 Apr 1995, Published online: 07 Jul 2009

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Keri L.H. Carpenter, Peter J. Kirkpatrick, Peter L. Weissberg, Iain R. Challis, Ian F. Dennis, Mark A. Freeman & Malcolm J. Mitchinson. (2003) Oral a-tocopherol Supplementation Inhibits Lipid Oxidation in Established Human Atherosclerotic Lesions. Free Radical Research 37:11, pages 1235-1244.
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Karin Müller, Keri L.H. Carpenter, Mark A. Freeman & Malcolm J. Mitchinson. (1999) Antioxidant BO-653 and human macrophage-mediated LDL oxidation. Free Radical Research 30:1, pages 59-71.
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Simon J. Hardwick, Kenl H. Carpenter, Nadine S. Law, Carina Van Der Veen, Christine E. Marchant, Rachel Hird & Malcolm J. Mitchinson. (1997) Toxicity of Polyunsaturated Fatty Acid Esters for Human Monocyte-Macrophages: The Anomalous Behaviour of Cholesteryl Linolenate. Free Radical Research 26:4, pages 351-362.
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Janelle Cleary, Detlef Mohr, Mark R. Adams, David S. Celermajer & Roland Stocker. (1997) Plasma and LDL Levels of Major Lipophilic Antioxidants are Similar in Patients with Advanced Atherosclerosis and Age-Matched Controls. Free Radical Research 26:2, pages 175-182.
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Articles from other publishers (18)

Francesc Guardiola, Alba Tres, Rafael Codony, Paul B. Addis, Scott D. Bergmann & James H. Zavoral. (2007) Lack of effect of oral supplementation with antioxidants on cholesterol oxidation product concentration of human plasma, as revealed by an improved gas chromatography method. Analytical and Bioanalytical Chemistry 389:1, pages 277-289.
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Roland Stocker & John F. KeaneyJr.Jr.. (2004) Role of Oxidative Modifications in Atherosclerosis. Physiological Reviews 84:4, pages 1381-1478.
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Joanne M. Upston, Leonard Kritharides & Roland Stocker. (2003) The role of vitamin E in atherosclerosis. Progress in Lipid Research 42:5, pages 405-422.
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Rafael Codony, Geoffrey Savage, Paresh Dutta & Francesc CuardiolaSandra "Garcia-Cruset a,b"Keri Carpenter b, Rafael Codony a & Francesc Guardiola a. 2002. Cholesterol and Phytosterol Oxidation Products. Cholesterol and Phytosterol Oxidation Products.
Joanne M. Upston, Xianwa Niu, Andrew J. Brown, Ryuichi Mashima, Hongjie Wang, Revathy Senthilmohan, Anthony J. Kettle, Roger T. Dean & Roland Stocker. (2002) Disease Stage-Dependent Accumulation of Lipid and Protein Oxidation Products in Human Atherosclerosis. The American Journal of Pathology 160:2, pages 701-710.
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Jiri Neuzil, Christian Weber & Anatol Kontush. (2001) The role of vitamin E in atherogenesis: linking the chemical, biological and clinical aspects of the disease. Atherosclerosis 157:2, pages 257-283.
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Reto Asmis & Jennifer Jelk. (2000) Vitamin E Supplementation of Human Macrophages Prevents Neither Foam Cell Formation Nor Increased Susceptibility of Foam Cells to Lysis by Oxidized LDL. Arteriosclerosis, Thrombosis, and Vascular Biology 20:9, pages 2078-2086.
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Shane R Thomas & Roland Stocker. (2000) Molecular action of vitamin E in lipoprotein oxidation:. Free Radical Biology and Medicine 28:12, pages 1795-1805.
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William A. Pryor, Wilhelm Stahl & Cheryl L. Rock. (2009) Beta Carotene: From Biochemistry to Clinical Trials. Nutrition Reviews 58:2, pages 39-53.
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Roland Stocker. 2000. Oxidative Stress and Vascular Disease. Oxidative Stress and Vascular Disease 27 47 .
John F. KeaneyJr.Jr.. 2000. Oxidative Stress and Vascular Disease. Oxidative Stress and Vascular Disease 195 211 .
Xianwa NiuVivienne ZammitJoanne M. UpstonRoger T. DeanRoland Stocker. (1999) Coexistence of Oxidized Lipids and α-Tocopherol in All Lipoprotein Density Fractions Isolated From Advanced Human Atherosclerotic Plaques. Arteriosclerosis, Thrombosis, and Vascular Biology 19:7, pages 1708-1718.
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Joanne M. Upston, Andrew C. Terentis & Roland Stocker. (1999) Tocopherol‐mediated peroxidation of lipoproteins: implications for vitamin E as a potential antiatherogenic supplement. The FASEB Journal 13:9, pages 977-994.
Crossref
P. K. Witting, J. M. Upston & R. Stocker. 1998. Fat-Soluble Vitamins. Fat-Soluble Vitamins 345 390 .
K. Fred Gey. (1998) Vitamins E plus C and interacting conutrients required for optimal health. BioFactors 7:1-2, pages 113-174.
Crossref
Reto Asmis. (2009) Physical Partitioning is the Main Mechanism of α‐Tocopherol and Cholesterol Transfer between Lipoproteins and P388D 1 Macrophage‐Like Cells . European Journal of Biochemistry 250:2, pages 600-607.
Crossref
Joëlle Goudable & Alain Favier. (1997) Radicaux libres oxygénés et antioxydants. Nutrition Clinique et Métabolisme 11:2, pages 115-120.
Crossref
Gerald Scott. 1997. Antioxidants in Science, Technology, Medicine and Nutrition. Antioxidants in Science, Technology, Medicine and Nutrition 262 308 .

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